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| 1 | Prognostic factors in patients with advanced cholangiocarcinoma: Role of surgery, chemotherapy and body mass index显示文摘AIM: To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS: A retrospective review of the medical records of 55 patients diagnosed with cholangio- carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to determine the impact of surgery, chemotherapy, body mass index, bilirubin level and other factors on survival. RESULTS: The median survival of all patients was 8.57 mo (0.03-105.2). Univariate analysis showed that low bilirubin level (< 10 mg/dL), radical surgery and chemotherapy administration were significantly associated with better survival (P = 0.012, 0.038 and 0.038, respectively). In subgroup analysis on patients who had no surgery, chemotherapy administration prolonged median survival significantly (17.0 mo vs 3.5 mo, P = 0.001). Multivariate analysis identifiedonly low bilirubin level < 10 mg/dL and chemotherapy administration as independent predictors associated with better survival (P < 0.05). CONCLUSION: Our data show that palliative and postoperative chemotherapy as well as a bilirubin level < 10 mg/dL are independent predictors of a significant increase in survival in patients with cholangiocarcinoma. | Mirna H Farhat Ali I Shamseddine Ayman N Tawil Ghina Berjawi Charif Sidani Wael Shamseddeen Kassem A Barada | 2008 | World Journal of Gastroenterology2008，14，20： | 9 |
| 2 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 3 | Left‐sided hepatic resection for hepatolithiasis: a longitudinal study of 110 patients显示文摘 | Omar Javed Shah Irfan Robbani Parveen Shah Showkat Ali Zargar Gul Javaid Ghulam N Yattoo Altaf Shah Farhat Mustafa | 2012 | HPB2012，，11： | 2 |
| 4 | Comparison of dot-ELISA and standard ELISA for detection of Neisseria meningitides outer membrane complex-specific antibodies 显示文摘 | Belo E F Farhat C K Gaspari E N | 2010 | Braz J Infect Dis2010，14，1： | 1 |
| 5 | The synergistic effect between erosion and corrosion of API pipeline in CO2 and saline medium显示文摘 | Aminul Islam M Farhat Zoheir N | 2013 | Tribology International2013，68，： | 1 |
| 6 | The association of bone mineral density measures with incident cardiovascular disease in older adults 显示文摘 | FARHAT G N NEWMAN A B SUTTON T K | 2007 | Osteoporosis Int2007，18，： | 1 |
| 7 | Stress-induced senescence predominates in endothelial cells i-solated from atherosclerotic chronic smokers 显示文摘 | Farhat N Thorin - Trescases N Voghel G | 2008 | Can JPhysiol Pharmacol2008，86，11： | 1 |
| 8 | Stress-induced senescence predominates in endothelial cells isolated from atherosclerotic chronic smokers显示文摘 | Farhat N Thorin-Trescases N Voghel G | | 0，，11： | 1 |
| 9 | Effect of grain size on friction and wear of nanoerystalline aluminum显示文摘 | FARHAT Z N DING Y NORTHWOOD D O | 1996 | Material Science and Engineer1996，206，： | 1 |
| 10 | Expression,prognostic and predictive impact of VEGF and bFGF in nonsmall cell lung cancer显示文摘 | Farhat F S Tfayli A Fakhruddin N | | 0，，02： | 1 |
| 11 | Functional IL- 18 promoter gene polymorphisms in Tunisian nasopharyngeal carcinoma patients显示文摘 | Farhat K Hassen E Bouzgarrou N | 2008 | Cytokine2008，43，2： | 1 |
| 12 | Functional IL-18 promoter gene polymorphisms in Tunisian nasopharyngeal carcinoma patients显示文摘 | Farhat K Hassen E Bouzgarrou N | 2008 | Cytokine2008，43，2： | 1 |
| 13 | Expression,prognostic and predictive impact of VEGF and bFGF in non-small cell lung cancer显示文摘 | Farhat FS Tfayli A Fakhruddin N | | 0，，02： | 1 |
| 14 | Microstructural characterization of WC-TiC-Co cutting tools during high-speed machining of P20 mould steel显示文摘 | Farhat Z N | 2003 | Materials Characterization2003，51，23： | 1 |
| 15 | In vitro micropropagation of peanut (Arachis hypogaea) through direct somatic embryogenesis and callus culture显示文摘 | Muhammad M I Farhat N Javaid I | 2011 | Intemational Journal of Agriculture and Biology2011，13，5： | 1 |
| 16 | 显示文摘 | Farhat Z N | 2003 | Mater Sci Engin A2003，361，： | 1 |
| 17 | Cellular senescence in endothelial cells from atherosclerotic patients is accelerated by oxidative stress associated with cardiovascular risk factors显示文摘 | Voghel G Thorin-Trescases N Farhat N | 2007 | Mech Ageing Dev2007，128，1112： | 1 |
| 18 | Background calibration with piecewise linearized error model for CMOS pipeline A/D converter显示文摘 | Yuan Jie Farhat N H van der Spiegel J | 2008 | IEEE Transactions on Circuits and Systems I: Regular Papers2008，55，1： | 1 |
| 19 | A new iterative algorithm for extrapolation of data available in multiple restricted regions with applications to radar imaging显示文摘 | H J Li N H Farhat Y S Shen | 1987 | IEEE Trans on AP1987，35，5： | 1 |
| 20 | Boron removal in new generation reverse osmosis(RO)membranes using two-pass RO without p H adjustment显示文摘 | Farhat A Ahmad F Hilal N | 2013 | Desalination2013，310，： | 1 |
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