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| 1 | Secreted protein acidic and rich in cysteine(SPARC)induces epithelial-mesenchymal transition,enhancing migration and invasion,and is associated with high Gleason score in prostate cancer显示文摘Secreted protein acidic and rich in cysteine(SPARC)is a matricellular protein highly expressed in bone tissue that acts as achemoattractant factor promoting the arrival of prostate cancer(PCa)cells to the bone marrow.However,the contribution of SPARCduring the early stages of tumor progression remains unclear.In this study,we show that SPARC is highly expressed in PCa tissueswith a higher Gleason score.Through stable knockdown and overexpression of SPARC in PC3 and LNCaP cells,respectively,here wedem on strate that en doge nous SPARC induces the epithelial-mesenchymal tran sition(EMT),decreasing E-cadheri n and cytokeratin18 and increasing N-cadheri n and vime ntin.Moreover,SPARC in duces the expression of EMT regulatory tran scription factors Snailfamily transcriptional repressor 1(Snail),Snail family transcriptional repressor 2(Slug),and zinc finger E-box binding homeobox 1(Zeb1).In addition,SPARC knockdown in PC3 cells decreases migration and invasion in vitro,without modifying cell proliferation.Our results indicate that SPARC might facilitate tumor progression by modifying the cellular phenotype in cancer cells. | Fernanda Lopez-Moncada Maria Jose Torres Enrique A Castellon Hector R Contreras | 2019 | Asian Journal of Andrology2019，21，6： | 5 |
| 2 | Modeling respiration rate of fresh fruits and vegetable for modified atmosphere packages: a review显示文摘 | Susana C F Fernanda A R Jeffrey K B | 2002 | Journal of Food Engineering2002，52，6： | 1 |
| 3 | Observing the performance of distribution systems with embeded generators显示文摘 | CIRIC R M PADILHA-FELTRIN A IARA FERNANDA EDD | 2004 | European Trans on Electrical Power2004，14，6： | 1 |
| 4 | Additional 3- nitropropanoyl esters of glucose from lndigoferasuffruticosa (Leguminosae) 显示文摘 | Wahnir S G Fernanda R Barison A | 2003 | Biochem Syst Ecol2003，31，2： | 1 |
| 5 | Modeling res- piration rate of shredded Galena kale for development of modi- fied atmosphere packaging 显示文摘 | Susana C F Fernanda A R O Jesus M F | 2002 | Journal of Food Engineering2002，54，4： | 1 |
| 6 | Electromagnetic Stimulation Combined with Aloe vera Increases Collagen Reorganization in Burn Repair显示文摘 | Sofia Poletti Leticia D. Lucke Fernanda O Bortolazzo Renata M. Acunha Marcos G. Mattos Femanda OG. Gaspi Thiago A. M. Andrade Maria Esmeria C. Amaral Andrea A .Aro Edson R Pimentel Marcelo AM. Esquisatto Fernanda A. S. Mendonga Glaucia M. T. Santos | 2018 | Journal of Pharmacy and Pharmacology2018，6，7： | 1 |
| 7 | Mathematical modeling of the kinetic of quality deterioration of intermediate moisture content banana during storage显示文摘 | Yan Zheng - yong Sousa - Gallagher Maria J Fernanda A R Oliveira | 2008 | Journal of Food Engineering2008，84，3： | 1 |
| 8 | Modelling 02 and CO2 Exchange for Development of Perforation-medi- ated Atmosphere Packaging显示文摘 | SUSANA C F FERNANDA A R ISABEL B M | 2000 | Journal of Food Engineer- ing2000，43，： | 1 |
| 9 | Modelling respiration rate of shredded Galega kale for development of modified atmosphere packaging 显示文摘 | Susana C F Fernanda A R O Jesus M F | 2002 | Journal of Food Engineering2002，54，4： | 1 |
| 10 | Extending shelf life of shredded Galega kale using a modified atmosphere package显示文摘 | Susana C F Fernanda A R O Jesus M F | 2004 | Electronic Journal of Environmental Agricultural and Food Chemistry2004，3，5： | 1 |
| 11 | Free radical scavenging of grape pomace extracts from cabernet sauvingnon (Vitis vinifera)显示文摘 | LUANDA M A S FERNANDA V PEDROSA R | 2008 | Bioresource Technology2008，99，17： | 1 |
| 12 | Shrinkage and porosity of banana, pineapple and mango slices during air-drying显示文摘 | Zhengyong Yan Maria J Sousa-Gallaghter Fernanda A R Oliveira | 2008 | Journal of Food Engineering2008，84，3： | 1 |
| 13 | Synthesis,characterization and evaluation of sulfonic resins as catalysts显示文摘 | M B Fernanda A B Coutinho R Rosane | 2004 | European Polymer Journal2004，40，： | 1 |
| 14 | Modelling ascorbic acid thermal degradation and browning in orange juice under aerobic conditions显示文摘 | Maria C M Fernanda A R O | 2001 | Int J Food Sci Technol2001，36，4： | 1 |
| 15 | Shrinkage and porosity of banana, pineapple and mango slices during air- drying 显示文摘 | Zhengyong Yan Maria J Sousa-Gallagher Fernanda A R Oliverira | 2008 | Journal of Food Engineering2008，84，： | 1 |
| 16 | Modelling respiration rate of shredded Galega kale for development of modified atmosphere packaging显示文摘 | Susana C F Fernanda A R O Jesus M F | 2002 | Journal of Food Engineering2002，54，4： | 1 |
| 17 | Free radical scavenging of grape pomace extracts from Cabernet sauvingnon (Vitis vinifera)显示文摘 | LUANDA M A S FERNANDA V PEDROSA R | 2008 | Bioresource Technology2008，99，17： | 1 |
| 18 | Extending shelf life of shredded Galega kale using a modified atmosphere package显示文摘 | Susana C F Fernanda A R O Jesus M F | 2004 | Electronic Journal of Environ mental Agricultural and Food Chemistry2004，3，5： | 1 |
| 19 | Modeling Respiration Rate of Fresh Fruits and Vegetable for Modified Armosphere Packages a Review显示文摘 | SUSANA C F FERNANDA A R JEFFREY K B | 2002 | Journal of Food Engi- neering2002，52，6： | 1 |
| 20 | Aerobic exercise reduces oxidative stress and improves vascular changes of small mesenteric and coronary arteries in hypertension显示文摘 | Fernanda R Roque Ana M Briones Ana B García‐Redondo María Galán Sonia Martínez‐Revelles Maria S Avenda?o Victoria Cachofeiro Tiago Fernandes Dalton V Vassallo Edilamar M Oliveira Mercedes Salaices | 2013 | Br J Pharmacol2013，，3： | 1 |
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