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| 1 | Pharmaceutical applications of AC Biosusceptometry显示文摘 | Luciana A. Corá Madileine F. Américo Fernando G. Romeiro Ricardo B. Oliveira José Ricardo A. Miranda | 2009 | European Journal of Pharmaceutics and Biopharmaceutics2009，，1： | 1 |
| 2 | Effects of meal size and proximal-distal segmentation on gastric activity显示文摘AIM:To evaluate the effects of meal size and three segmentations on intragastric distribution of the meal and gastric motility,by scintigraphy.METHODS:Twelve healthy volunteers were randomly assessed,twice,by scintigraphy.The test meal consisted of 60 or 180 mL of yogurt labeled with 64 MBq 99m Tc-tin colloid.Anterior and posterior dynamic frames were simultaneously acquired for 18 min and all data were analyzed in MatLab.Three proximal-distal segmentations using regions of interest were adopted for both meals.RESULTS:Intragastric distribution of the meal between the proximal and distal compartments was strongly influenced by the way in which the stomach was divided,showing greater proximal retention after the 180 mL.An important finding was that both dominant frequencies (1 and 3 cpm) were simultaneously recorded in the proximal and distal stomach;however,the power ratio of those dominant frequencies varied in agreement with the segmentation adopted and was independent of the meal size.CONCLUSION:It was possible to simultaneously evaluate the static intragastric distribution and phasic contractility from the same recording using our scintigraphic approach. | Madileine F Américo Marjorie V Ietsugu Fernando G Romeiro Luciana A Corá Ricardo B Oliveira José Ricardo A Miranda | 2010 | World Journal of Gastroenterology2010，16，46： | 1 |
| 3 | Gastroesophageal reflux disease and non-esophageal cancer显示文摘The association of gastroesophageal reflux disease(GERD) and esophageal cancer is well known.The carcinogenic properties of the gastroduodenal contents may also lead to cancer in target organs for GERD especially considering that they do not have intrinsic protective mechanisms as found in the esophagus.This review focuses on the putative relation between GERD and non-esophageal cancer.Most of the papers reviewed are far from ideal to prove the relationship of extraesophageal cancer and GERD since a small number ofpatients is presented,most do not control cases based on tobacco usage and obesity,and the diagnosis of GERD is variable,not always from an objective measurement such as p H monitoring but relying on symptoms in most reports.Nevertheless,head and neck and lung cancer have a growing incidence parallel to GERD and a shift towards non-smoking,female gender and adenocarcinoma(compared to squamous cell carcinoma) is arising,similar to the example of esophageal cancer with the exception of the female gender. | Fernando AM Herbella Sebastiao Pannocchia Neto Ilka Lopes Santoro Licia Caldas Figueiredo | 2015 | World Journal of Gastroenterology2015，21，3： | 1 |
| 4 | Measurement accuracy in congenital scoliosis显示文摘 | Fernando AM Robert BW John EL | 2001 | Bone Joint Surg2001，83，1： | 1 |
| 5 | Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharide 显示文摘 | Felts PA Woolston AM Fernando HB | 2005 | Brain2005，128，7： | 1 |
| 6 | Wireless laser-assisted angioplasty of the superficial femoral artery in patients with critical limb ischemia who have failed conventional percutaneous revascularization显示文摘 | Fernando Boccalandro AM Sdringola S Rosales OR | 2004 | Catheter Cardjovasc Interv2004，63，： | 1 |
| 7 | Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharide显示文摘 | Felts PA Woolston AM Fernando HB | 2005 | Brain2005，128，7： | 1 |
| 8 | Preterm birth, ovarian endometriomata, and assisted reproduction technol- ogies显示文摘 | Fernando S Breheny S Jaques AM | 2009 | Ferfil Steril2009，91，2： | 1 |
| 9 | High resolution manometric findings in patients with Chagas' disease esophagopathy显示文摘Objective:To describe high resolution manometry features of a population of symptomatic- patients with Chagas’ disease esophagopathy(CDE).Methods:Sixteen symptomatic dysphagic patients with CDE[mean age(54.81±13.43) years,10 women]were included in this study.All patients underwent a high resolution manometry.Results:Mean lower esophageal sphincter(LES) extension was(3.02±1.17) cm with a mean basal pressure of(15.25±7.00) mmHg.Residual pressure was(14.31±9.19) mmHg.Aperistalsis was found in all 16 patients.Achalasia with minimal esophageal pressurization(type I) was present in 25%of patients and achalasia with esophageal compression(type 2) in 75%,according to the Chicago Classification.Upper esophageal sphincter(UES) mean basal pressure was(97.96±54.22) mmHg with a residual pressure of(12.95±6.42) mmHg.Conclusions:Our results show that LES was hypotensive or normotensive in the majority of the patients.Impaired relaxation was found in a minority of our patients.Aperistalsis was seen in 100%of patients.UES had impaired relaxation in a significant number of patients. Further clinical study is needed to investigate whether manometric features can predict outcomes following the studies of idiopathic achalasia.. | Luciana C Silva Fernando PP Vicentine Fernando AM Herbella | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，2： | 0 |
| 10 | Can high resolution manometry parameters for achalasia be obtained by conventional manometry?显示文摘High resolution manometry(HRM) is a new technology that made important contributions to the field of gastrointestinal physiology. HRM showed clear advan-tages over conventional manometry and it allowed the creation of different manometric parameters. On the other side, conventional manometry is still wild available. It must be better studied if the new technology made possible the creation and study of these parameters or if they were always there but the colorful intuitive panoramic view of the peristalsis from the pharynx to the stomach HRM allowed the human eyes to distinguish subtle parameters unknown or uncomprehend so far and if HRM parameters can be reliably obtained by conventional manometry and data from conventional manometry still can be accepted in achalasia studies. Conventional manometry relied solely on the residual pressure to evaluate lower esophageal sphincter(LES) relaxation while HRM can obtain the Integrated Relaxation Pressure. Esophageal body HRM parameters defines achalasia subtypes, the Chicago classification, based on esophageal pressurization after swallows. The characterization of each subtype is very intuitive by HRM but also easy by conventional manometry since only wave amplitudes need to be measured. In conclusion, conventional manometry is still valuable to classify achalasia according to the Chicago classification. HRM permits a better study of the LES. | Fernando AM Herbella Marco G Patti | 2015 | World Journal of Gastrointestinal Pathophysiology2015，6，3： | 0 |
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