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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Physical characterization of hydroxyapatite porous scaffolds for tissue engineering 显示文摘 | Teixeira S Rodriguez M A Pena P De Aza A H De Aza S Ferraz M P Monteiro F J | 2009 | Materials Science & Engineering C-Biomimetic and Supramolecular Systems2009，29，5： | 1 |
| 3 | Quercetin in- duces structural chromosomal aberrations and uncom- mon rearrangements in bovine cells transformed by the E7 protein of bovine papillomavirus type 4显示文摘 | Leal A M Ferraz O P Carvalho C | 2003 | Vet Comp Onco12003，1，1： | 1 |
| 4 | The azo dyes DisperseRed 1 and Disperse Orange 1 increase the micronuclei frequenciesin human lymphocytes and in HepG2 cells 显示文摘 | Chequer F M Angeli J P Ferraz E R | 2009 | Mutation Research2009，676，12： | 1 |
| 5 | CaO-P2O5 glass hydroxyapatite double-layer plasma-sprayed coating:in vitro bioactivity evaluation显示文摘 | Ferraz M P Monteiro F J Santos J D | 1999 | J Biomed Mater Res1999，45，： | 1 |
| 6 | Effect of chemical composition on hydrophobicity and zeta potential of plasma sprayed HA/CaO-P2O5 glass coatings显示文摘 | Ferraz M P Monteiro F J Serro A P | 2001 | Biomaterials2001，22，： | 1 |
| 7 | Enzyme production and chemical alterations of Eucalyptus grandis wood during biodegradation by Ceriporiopsis subvermispora in cultures supplemented with Mn^2+, corn steep liquor and glucose 显示文摘 | Vicentim M P Ferraz A | 2007 | Enzyme and Microbial Technology2007，40，4： | 1 |
| 8 | Nanohydroxyapatite Microspheres as Delivery System for Antibiotics:Release Kinetics,Antimicrobial Activity,and Interaction with Osteoblasts显示文摘 | Ferraz M P Mateus A Y Sousa J C | 2007 | Wiley InterScience2007，81，4： | 1 |
| 9 | Modulation for three-phase transformer-less z-source inverter to reduce leakage currents in photovohaic sys- tems 显示文摘 | F Bradaschia M C Cavalcanti P E P Ferraz | 2011 | IEEE Transactions on Industrial Electronics2011，58，12： | 1 |
| 10 | A conservation GAP analysis of Brazil Amazonian vegetation显示文摘 | Fearnside P M J Ferraz | 1995 | Conservation Biology1995，9，： | 1 |
| 11 | CaO-P205 Glass- Hydroxyapatite Thin films Obtained by Laser Ablation: Characterization and in Vitro Bioactivity 显示文摘 | Ferraz M P Monteiro F J Giao D | 2004 | Key Eng Mater2004，，： | 1 |
| 12 | The azo dyes disperse red 1 ant disperse orange increase the micronuclei frequen cies in human lymphocytes and in HepG2 cells显示文摘 | CHEQUER F M D ANGELI J P F FERRAZ E R A | 2009 | Mutation ResearchGenetic Toxicology and Environmental Mutagenesis2009，676，1： | 1 |
| 13 | Improved high-permethod for GABA and glutamate determination in regions of the rodent brain 显示文摘 | de Freitas silva D M Ferraz V P formance liquid chromatographic Ribeiro A M | 2009 | J Neurosci Methods2009，177，2： | 1 |
| 14 | Coupling ofan electrodialysis unit to a hollow fiber bioreactor for separationof gluconic acid from sorbitol produced by Zymomonas mobilispermeabilized cells显示文摘 | FERRAZ H C ALVES L M BORGES C P | 2001 | Membrane Sci2001，，191： | 1 |
| 15 | Improved high performance liquid Chromatographic method for GABA and glutamate determination in regions of the rodent brain显示文摘 | Silva D M F Ferraz V P Ribeiro A M | 2009 | Journal of Neuroscience Methods2009，177，： | 1 |
| 16 | Lack of Evidence of Upper Gastrointestinal Endoscopy as a Risk Factor for Transmission of Hepatitis B Virus 「letter」显示文摘 | Ferrari A P Geocze S Ferraz M L G | 1991 | Endoscopy1991，23，： | 1 |
| 17 | Infection ,f or- thopedic implants with emphasis on bacterial adhesion process and techniques used in studying bacterial-mate- rial interactions 显示文摘 | Ribeiro M Monteiro F J Ferraz M P | 2012 | Biomatter2012，2，4： | 1 |
| 18 | Meta-analysis of sulphasalazine in ankylosing spondylitis显示文摘 | Tugwell P Goldsmith C | 1990 | J Rheumatol1990，17，11： | 1 |
| 19 | CaO-P2O5 Glass-Hydroxyapatite Thin films obtained by laser ablation:characterization and in vitro bioactivity evaluation显示文摘 | Ferraz M P Monteiro F J Giao D | 2004 | Key Engineering Materials2004，，： | 1 |
| 20 | Flow cytometry analysis of effects of glass on response of osteosarcoma cells to plasma-sprayed hydroxyapatite/CaO-P2O5 coatings显示文摘 | KNOWLES J C OLSEN I | 1999 | J Biomed Mater Res1999，47，： | 1 |
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