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| 1 | Nat Biotechnol:将人星形胶质细胞重编程为多巴胺能神经元,有助治疗帕金森病显示文摘帕金森病是一种主要影响运动系统的神经退行性疾病。它的特征在于大脑中的多巴胺能神经元(dopaminergic neuron)渐进性丧失。尽管当前的疗法旨在补充多巴胺水平,但是没有一种疗法能够恢复这些丢失的细胞。如今。在一项新的研究中,来自瑞典、奥地利、西班牙和美国的研究人员开发出一种方法:将神经胶质细胞(glialcell)转化为活性的多巴胺能神经元,并且所产生的多巴胺能神经元能够部分恢复帕金森病模式小鼠的运动功能。这项概念验证研究可能为开发出一种治疗这种疾病的新方法铺平道路。 | Pia Rivetti di Val Cervo, Elisa Martín-Montañez, Enrique M Toledo, Gioele La Manno, Sara Padrell Sánchez, Sten Linnarsson Ernest Arenas Roman A Romanov, Christian Pifl Tibor Harkany Roman A Romanov, Giada Spigolon, Débora Masini, Michael Feyder, Tibor Harkany Gilberto Fisone Elisa Martín-Montañez Yi-Han Ng Marius Wernig | 2017 | 现代生物医学进展2017，17，17： | 11 |
| 2 | Signaling in the basal ganglia: postsynaptic and presynaptic mechanisms显示文摘 | Fisone G Hakansson K Borgkvist A | 2007 | Physiol Be- hav2007，92，2： | 1 |
| 3 | Well-Being显示文摘 | CLARKE S R HAWORTH B K FISONE G | 2011 | Psychological Bulletin2011，98，16： | 1 |
| 4 | DARPP-32: an integra- tor of neurotransmission显示文摘 | Svenningson P Nishi A Fisone G | 2004 | Annu Rev Pharmacol Toxico|2004，44，： | 1 |
| 5 | Parkinson's disease: Levodopa-induced dyskinesia and signal transduction~显示文摘 | Santini E Valjent E Fisone G | 2008 | FEBS J2008，275，7： | 1 |
| 6 | Diplopia after retinal detachment surgery 显示文摘 | Fison PN Chignell AH | 1987 | Br J Ophthalmol1987，71，7： | 1 |
| 7 | False position of the posterior pole as a fundus landmark显示文摘 | Fison J | 1956 | Br J Ophthalmol1956，40，4： | 1 |
| 8 | mGlu5R promotes glutamate AMPA receptor phosphorylation via activation of PKA/DARPP-32 signaling in striatopallidal medium spiny neurons显示文摘 | Dell'anno MT Pallottino S Fisone G | 2013 | Neuropharmacology2013，66，： | 1 |
| 9 | Parkinson's disease:levodopa-induced dyskinesia and signal transduction显示文摘 | Santini E Valjent E Fisone G | | 0，，07： | 1 |
| 10 | Adenosine A2A receptors and basal ganglia physiology显示文摘 | Schiffmann SN Fisone G Moresco R | 2007 | Prog Neurobiol2007，83，： | 1 |
| 11 | DARPP-32 : an integrator of 显示文摘 | Svenningsson P Nishi A Fisone G | 2004 | Annu Rev Pharmacol Toxicol2004，44，： | 1 |
| 12 | DARPP-32, an inte?grator of neurotransmission显示文摘 | Svenningsson P Nishi A Fisone G et at | 2004 | Annu Rev Pharmacol Toxicol2004，44，： | 1 |
| 13 | DARPP-32: an in- tegrator of neurotransmission显示文摘 | SVENNINGSSON P NISHI A FISONE G | 2004 | Annu Rev Pharmacol Toxicol2004，44，： | 1 |
| 14 | Signaling in the basal ganglia:Postsynaptic and presynaptic mechanisms显示文摘 | Fisone G Hakansson K Borgkvist A | 2007 | Physiol Behav2007，1092，12： | 1 |
| 15 | DARPP-32 : An inlegrator of meurotransmission 显示文摘 | Svenningsson P Nishi A Fisone G | 2004 | Annu Rev Pharmacol Toxicol2004，44，3： | 1 |
| 16 | Identification of the phosphorylation site for cAMP-dependent protein kinase on Na-K-ATPase and effects of site-directed mutagenesis显示文摘 | Fisone G Cheng S X Nairn A C | 1994 | J Biol Chem1994，269，： | 1 |
| 17 | Understanding cognitive deficits in Parkinsong disease:lessons from preelinical animal models显示文摘 | Solari N Bonito-Oliva A Fisone G | 2013 | Learn Mem2013，20，10： | 1 |
| 18 | DARPP-32: an integrator of neurotransmission显示文摘 | Svenningsson P Nishi A Fisone G | 2004 | Annu Rev Pharmacol Toxicol2004，44，： | 1 |
| 19 | Adenosine A2A receptors and basal ganglia physiology显示文摘 | Schiffmann S N Fisone G Moresco R | 2007 | Prog Neuro- bio12007，83，5： | 1 |
| 20 | DARPP-32:an integrator of neurotransmission显示文摘 | Svenningsson P Nishi A Fisone G | 2004 | Annual Review of Pharmacology&Toxicology2004，44，1： | 1 |
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