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258篇 您的检索式:作者名="Foo J"
    题名 作者 年代 出处 被引量
1Claudin-11 and occludin are major contributors to Sertoli cell tight junction function, in vitro显示文摘Sertoli 房间紧密的连接(TJ ) 是血睾丸障碍的关键部件,在它扣押开发在生精的小管以内经历精子发生的细菌房间的地方。神经质地调整的 claudin-11 是在不孕涉及障碍功能和它的鼠科的猛烈结果的批评 transmembrane 蛋白质。我们试图估计份量上到 TJ 功能的 claudin-11 的贡献的意义在 vitro,使用调停 siRNA 的基因 silencing。我们也进行了 occludin 的贡献的分析, TJ 的另一内在的 transmembrane 蛋白质。claudin-11 或 occludin 的 Silencing 在一个不成熟的老鼠 Sertoli 房间文化模型用 siRNA 被进行。Transepithelial 电的抵抗被用来在整个文化估计份量上 TJ 功能。在 siRNA 处理以后的二天,房间为对 mRNA 的 RT-PCR 评价为连接蛋白质或 lyzed 的 immunocytochemical 本地化被修理表示。claudin-11, occludin,或两个的 Silencing 在 55% 的 TJ 功能导致了重要减少(P <0.01 ) , 51%(P <0.01 ) ,并且 62%(P <0.01 ) 分别地。数据在到 Sertoli 房间 TJ 的指向的蛋白质的本地化是有在 mRNA 表示和显著减小的重要减少的伴随物。我们提供 claudin-11 显著地贡献的量的证据(P <0.01 ) 到 Sertoli 房间 TJ 在 vitro 工作。有趣地, occludin,神经质地在不孕被调整然而并非含有直到迟了的成人生活,也是一重要(P <0.01 ) 贡献者到障碍功能。我们的数据与一致在清楚地为这些表明一个角色的 vivo 研究,在维持正常 TJ 障碍的蛋白质组织并且工作。Mark J McCabe Caroline FH Foo Marcel E Dinger Peter M Smooker Peter G Stanton 2016Asian Journal of Andrology2016,18,4:7
2Vaccinia vi- rus exhibits cell-type-dependent entry characteristics显示文摘Whitbeck J C Foo C H Ponce D E 2009Virology2009,385,2:1
3Characteristics of pyogenic liver abscess patients with and without diabetes mellitus 显示文摘Foo NP Chen KT Lin H J 2010Am J Gastroenterol2010,105,2:1
4Antibiotic Resistance and Plasmid Profiles of Vibrio Isolates from Cultured Silver Sea Bream,Sparus sarba显示文摘Li J Yie J Foo R W T 1999Marine Pollution Bulletin1999,39,112:1
5Better characterization of arsenic and chromium in soils :A field-scale example显示文摘Hale J R Foos A Zubrow J S 1997Journal of Soil Con- tamination1997,6,:1
6A single serum glucose measurement predicts adverse outcomes across the whole range of acute coronary syndromes 显示文摘Foo K Cooper J Deaner A 2003Heart2003,89,:1
7Path planning of unmanned aerial vehicles using B-splines and particle swarm optimization显示文摘FOO J L KNUTZON J KALIVARAPU V 2009Journal of Aerospace Computing Information and Communication2009,6,4:1
8Procyanidin dimers and trimers from Douglas firinner Bark 显示文摘Foo L Y Karchesy J J 1989Phytochemistry1989,28,6:1
9Effects of occupational exposure to toluene: a neurepsychological study on works in Singapore 显示文摘Beoy KM Foo SC Jeyardtnam J 1997Ann Acad Med Singapore1997,26,2:1
10Path planning of unmanned aerial vehicles using B-Splines and particle swarm optimization显示文摘Foo J L Knutzon J Kalivarapu V 2009Journal of Aerospace Computing Information and Communication2009,6,4:1
11Acoustic radiation force im- pulse imaging of human prostates ex vivo显示文摘Zhai L Madden J Foo WC 2010Ultrasound Med Bi- ol2010,36,4:1
12The clinical utility of brain natriuretic peptide in paediatric left ventrieular failure 显示文摘Mangat J Carter C Riley G Foo Y Burch M 2009Eur J Heart Fail2009,11,1:1
13Thermal comfort in the humid tropics:Field experiments in air conditioned and naturally ventilated buildings in Singapore显示文摘DE DEAR R J LEOW K G FOO S C 1991International Journal of Biometeorology1991,34,4:1
14An experimental and numerical study of the compaction of alumina agglomerates显示文摘Foo Y Y Sheng Y Brisco B J 2004Int J Solids Structures2004,41,21:1
15Flavonoids from the leaves of Kalmia latifolia显示文摘El-Naggar S F El-Feraly F S Foos J S 1980J Nat Prod1980,43,6:1
16Stretchable transparent Ionic conductors显示文摘Keplinger C Sun J Y Foo C C Rothemund P Whi- resides G M Suo Z 2013Science2013,341,:1
17Adjuvant therapy for rectal cancer显示文摘FOO K F MICHEAL M ZALCBERG J 2002Sem in Colon Rectum Surg2002,13,4:1
18Geraniin and amariin, ellagitannins from Phyllanthus amarus, protect liver cells against ethanol induced cytotoxicity 显示文摘Londhe J S Devasagayam T P A Foo L Y 2012Fitoterapia2012,83,8:1
19Single-incision laparoscopic appendectomy:prospective case series at a single centre in Singapore显示文摘Goel R Buhari SA Foo J 2011Surg Laparosc Endosc Percutan Tech2011,21,5:1
20Single-incision laparoscopic appendectomy:prospective case series at a single centre in Singapore显示文摘Goel R Buhari SA Foo J 0,,05:1
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