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| 1 | Clinical expression of insulin resistance in hepatitis C and B virus-related chronic hepatitis:Differences and similarities显示文摘AIM:To investigate the prevalence of the clinical parameters of insulin resistance and diabetes in patients affected by chronic hepatitis C(CHC) or chronic hepatitis B(CHB) . METHODS:We retrospectively evaluated 852 consecutive patients(726 CHC and 126 CHB) who had undergone liver biopsy.We recorded age,sex,ALT,type 2 diabetes and/or metabolic syndrome(MS) ,body mass index(BMI) ,and apparent disease duration(ADD) . RESULTS:Age,ADD,BMI,prevalence of MS and diabetes in patients with mild/moderate liver fibrosis were significantly higher in CHC.However,the degree of steatosis and liver fibrosis evaluated in liver biopsies did not differ between CHC and CHB patients.At multivariate analysis,age,sex,BMI,ALT and diabetes were independent risk factors for liver fibrosis in CHC,whereas only age was related to liver fibrosis in CHB. We also evaluated the association between significant steatosis(>30%) and age,sex,BMI,diabetes,MS and liver fibrosis.Diabetes,BMI and liver fibrosis were associated with steatosis>30%in CHC,whereas only age and BMI were related to steatosis in CHB. CONCLUSION:These data may indicate that hepatitis C virus infection is a risk factor for insulin resistance. | Marcello Persico Mario Masarone Vincenzo La Mura Eliana Persico Francesco Moschella Monica Svelto Savino Bruno Roberto Torella | 2009 | World Journal of Gastroenterology2009,15,4: | 8 |
| 2 | Clinical neurophysiology and imaging of nerve injuries:preoperative diagnostic work-up and postoperative monitoring显示文摘Peripheral nerve injuries are a heterogeneous group of lesions that may occurs secondary to various causes.Several different classifications have been used to describe the pathophysiological mechanisms leading to the clinical deficit,from simple and reversible compression-induced demyelination,to complete transection of nerve axons.Neurophysiological data localize,quantify,and qualify(demyelination vs.axonal loss)the clinical and subclinical deficits.High-resolution ultrasound can demonstrate the morphological extent of nerve damage,fascicular echotexture(epineurium vs.perineurium,focal alteration of the cross-section of the nerve,any neuromas,etc.),and the surrounding tissues.High field magnetic resonance imaging provides high contrast neurography by fat suppression sequences and shows structural connectivity through the use of diffusion-weighted sequences.The aim of this review is to provide clinical guidelines for the diagnosis of nerve injuries,and the rationale for instrumental evaluation in the preoperative and postoperative periods.While history and clinical approach guide neurophysiological examination,nerve conduction and electromyography studies provide functional information on conduction slowing and denervation to assist in monitoring the onset of re-innervation.High-resolution nerve imaging complements neurophysiological data and allows direct visualization of the nerve injury while providing insight into its cause and facilitating surgical treatment planning.Indications and limits of each instrumental examination are discussed. | Andrea Gagliardo Francesca Toia Francesco Maggì Alessio Vincenzo Mariolo Michele Cillino Francesco Moschella | 2015 | Plastic and Aesthetic Research2015,2,1: | 1 |
| 3 | 重新讨论锁骨上区的血管解剖学:游离锁骨上穿支皮瓣的可行性显示文摘背景锁骨上皮肤已被广泛的研究,并在面部和颈部再造术中作为带蒂皮瓣使用。锁骨上皮肤作为游离皮瓣的使用不像带蒂皮瓣那么广泛。作者对锁骨上区实施了解剖研究,目的是评估获得供区瘢痕位于锁骨上折痕处的游离锁骨上皮瓣的可行性。本文描述了作者的解剖研究和初步的临床应用结果。方法对25例(巴黎笛卡尔大学15例新鲜尸体,利用彩色乳胶注射;因斯布鲁克医科大学10例甲醛溶液固定,不注射)尸体进行解剖研究,分析游离锁骨上穿支皮瓣的血管化和可行性。皮瓣用于巴勒莫大学整形外科的2例患者,1例面部修复术,1例癌症切除后口内修复术。结果在锁骨上区域平均发现4个来自颈横动脉的穿支。静脉穿支流人表浅静脉丛,而非颈横动脉的并行静脉。2例皮瓣均成功移植。结论锁骨上皮肤的血管化依赖来自颈横动脉的皮肤穿支,并流人表浅静脉丛。以这些血管为基础,游离的锁骨上皮瓣可安全获取,瘢痕隐藏在锁骨上折痕处。此皮瓣的初步临床应用取得满意效果,提示临床应用的可能性。 | Adriana Cordova Roberto Pirrello Salvatore D'Arpa Johannes Jeschke Erich Brenner Francesco Moschella 朱利娜 魏峰(译) 高景恒(译) | 2013 | 中国美容整形外科杂志2013,24,5: | 0 |
| 4 | 面部提升SMAS折叠瓣修复颞部巨大缺损:再造外科与美容外科的交汇显示文摘背景颞区巨大缺损可以采用皮片、带蒂或游离瓣修复重建。但由于皮片移植形似补丁、局部可用的组织瓣缺乏以及游离瓣与周围皮肤色差较大的原因,致使这些方法的效果不尽人意。本文应用浅表肌肉腱膜系统(SMAS)折叠术以局部皮瓣修复颞区巨大缺损,拓展了面颈部皮瓣的应用范围。方法颞区缺损手术切口采用面部提升术手术切口,以便组织瓣的提升。荷包缝合使SMAS瓣折叠, | Salvatore D'Arpa Adriana Cordova Roberto Pirrello Giovanni Zabbia Daniel Kalbermatten Francesco Moschella 石杰(译) 袁继龙 魏峰(译) 高景恒(译) | 2011 | 中国美容整形外科杂志2011,22,9: | 0 |