|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | In-phase thermal–mechanical fatigue investigation on hollow single crystal turbine blades显示文摘Thermal–mechanical fatigue(TMF)is the primary cause of failure of nickel-based single crystal turbine blades.TMF experiments have been performed on the critical section which is subjected to the most serious damage and determined by numerical calculation combined with service failure experience.An experimental system including the loading,heating,air cooling,water cooling,and control subsystems,is constructed to satisfy the TMF experimental requirements.This experimental system can simulate the stress feld,temperature feld,air cooling process,and TMF spectrum on the critical section under service conditions in a laboratory environment.A metal loading device and a new induction coil are developed to achieve the required stress and temperature distributions on the critical section,respectively.TMF experimental results have indicated that cracks initiated at the trailing edge of the suction surface on the critical section.Based on these experiments,life prediction and failure analysis of hollow single crystal turbine blades can be investigated. | Wang Rongqiao Jing Fulei Hu Dianyin | 2013 | Chinese Journal of Aeronautics2013，26，6： | 7 |
| 2 | Intestinal dysbiosis exacerbates the pathogenesis of psoriasis-like phenotype through changes in fatty acid metabolism显示文摘The intestinal microbiota has been associated with host immunity as well as psoriasis;however,the mechanism of intestinal microbiota regulating psoriasis needs to be demonstrated systematically.Here,we sought to examine its role and mechanism of action in the pathogenesis of psoriasis.We found that the severity of psoriasis-like skin phenotype was accompanied by changes in the composition of the intestinal microbiota.We performed co-housing and fecal microbial transplantation(FMT)experiments using the K14-VEGF transgenic mouse model of psoriasis and demonstrated that the transfer of intestinal microbiota from mice with severe psoriasis-like skin phenotype exacerbated psoriasiform skin inflammation in mice with mild symptoms,including increasing the infiltration and differentiation of Th17,and increased the abundance of Prevotella,while decreasing that of Parabacteroides distasonis,in the colon.These alterations affected fatty acid metabolism,increasing the abundance of oleic and stearic acids.Meanwhile,gentamicin treatment significantly reduced the abundance of Prevotella and alleviated the psoriasis-like symptoms in both K14-VEGF mice and imiquimod(IMQ)-induced psoriasis-like mice.Indeed,administration of oleic and stearic acids exacerbated psoriasis-like symptoms and increased Th17 and monocyte-derived dendritic cell infiltration in the skin lesion areas in vivo,as well as increased the secretion of IL-23 by stimulating DCs in vitro.At last,we found that,treatment of PDE-4 inhibitor alleviated psoriasis-like phenotype of K14-VEGF mice accompanied by the recovery of intestinal microbiota,including the decrease of Prevotella and increase of Parabacteroides distasonis.Overall,our findings reveal that the intestinal microbiota modulates host metabolism and psoriasis-like skin inflammation in mice,suggesting a new target for the clinical diagnosis and treatment of psoriasis. | Qixiang Zhao Jiadong Yu Hong Zhou Xiaoyan Wang Chen Zhang Jing Hu Yawen Hu Huaping Zheng Fanlian Zeng Chengcheng Yue Linna Gu Zhen Wang Fulei Zhao Pei Zhou Haozhou Zhang Nongyu Huang Wenling Wu Yifan Zhou Jiong Li | 2023 | Signal Transduction and Targeted Therapy2023，8，2： | 2 |
| 3 | Stress-controlled LCF experiments and ratcheting behaviour simulation of a nickel-based single crystal superalloy with [001] orientation显示文摘Uniaxial ratcheting behaviour and low cycle fatigue(LCF)failure mechanism of nickel-based single crystal superalloy DD6 with[001]orientation are investigated through the stresscontrolled LCF tests with stress ratio of-1.Then the deformation behaviour during the wholelifetime from the beginning of the experiment to the fracture of the specimen,as well as the fractographic/metallographic morphology,are compared with the strain-controlled LCF experimental results.Through the scanning electron microscope(SEM)observations,it is shown that the failure characteristics under stress-controlled LCF loading are similar with those under strain-controlled loading.Nevertheless,unlike strain-controlled LCF loading,even under fully reversed cycle loading for stress-controlled LCF,DD6 shows significant ratcheting behaviour due to the tensioncompression asymmetry.In addition,the LCF lifetimes under stress control are significantly shorter than the LCF lifetimes under strain control,and the culprit might be the detrimental effect of ratcheting strain on LCF lifetime.Based on these phenomena,an improved crystal plasticity constitutive model on the basis of slip-based Walker constitutive model is developed through modifying the kinematic hardening rule in order to overcome the inaccurate prediction of decelerating stageand stable stage of ratcheting behaviour.Furthermore,combining the continuum damage mechanics,a damage-coupled crystal plasticity constitutive model is proposed to reflect the damage behaviour of DD6 and the accelerating stage of ratcheting behaviour.The simulation results for the stress-controlled LCF deformation behaviour including the whole-lifetime ratcheting behaviour show good agreement with the experimental data. | Bin ZHANG Rongqiao WANG Dianyin HU Kanghe JIANG Jianxing MAO Fulei JING Xinyi HAO | 2021 | Chinese Journal of Aeronautics2021，34，8： | 2 |
| 4 | Review of Numerical Simulation of TGO Growth in Thermal Barrier Coatings显示文摘Thermally grown oxide(TGO)is a critical factor for the service life of thermal barrier coatings(TBC).Numerical simulations of the growth process of TGO have become an effective means of comprehensively understanding the progressive damage of the TBC system.At present,technologies of numerical simulation to TGO growth include two categories:coupled chemical-mechanical methods and mechanical equivalent methods.The former is based on the diffusion analysis of oxidizing elements,which can describe the influence of bond coat(BC)consumption and phase transformation in the growth process of TGO on the mechanical behavior of each layer of TBC,and has high accuracy for the thickness evolution of TGO,but they cannot describe the lateral growth of TGO and the rumpling phenomenon induced.The latter focuses on describing the final stress and strain state after the growth of a specific TGO rather than the complete growth processes of TGO.Based on the measured TGO thickness growth curve,simulations of thickening and lateral growth can be achieved by directly applying anisotropic volumetric strain to oxidized elements and switching elements properties from the BC to the TGO. | Quan Wen Fulei Jing Changxian Zhang Shibai Tang Junjie Yang | 2022 | Computer Modeling in Engineering & Sciences2022，，8： | 1 |
| 5 | Macro-phenomenological high-strain-rate elastic fracture model for ice-impact simulations显示文摘The ice impact can cause a severe damage to an aircraft’s exposed structure,thus,requiring its prevention.The numerical simulation represents an effective method to overcome this challenge.The establishment of the ice material model is critical.However,ice is not a common structural material and exhibits an extremely complex material behavior.The material models of ice reported so far are not able to accurately simulate the ice behavior at high strain rates.This study proposes a novel high-precision macro-phenomenological elastic fracture model based on the brittle behavior of ice at high strain rates.The developed model has been compared with five reported models by using the smoothed particle hydrodynamics method so as to simulate the ice-impact process with respect to the impact speeds and ice shapes.The important metrics and phenomena(impact force history,deformation and fragmentation of the ice projectile and deflection of the target)were compared with the experimental data reported in the literature.The findings obtained from the developed model are observed to be most consistent with the experimental data,which demonstrates that the model represents the basic physics and phenomena governing the ice impact at high strain rates.The developed model includes a relatively fewer number of material parameters.Further,the used parameters have a clear physical meaning and can be directly obtained through experiments.Moreover,no adjustment of any material parameter is needed,and the consumption duration is also acceptable.These advantages indicate that the developed model is suitable for simulating the iceimpact process and can be applied for the anti-ice impact design in aviation. | Jiang FAN Qinghao YUAN Fulei JING Guangchen BAI Xiuli SHEN | 2023 | Chinese Journal of Aeronautics2023，36，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员