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| 1 | Spatial-temporal patterns of vegetation dynamics and their relationships to climate variations in Qinghai Lake Basin using MODIS time-series data显示文摘全球温暖在最近的年里导致了重要植被变化。为环境适应的更好的理解在植被变化上调查气候的变化(温度和降水) 的效果到气候的变化是必要的。在这份报纸,我们在 GIS 集中了于多方法和空间分析技术的集成和申请学习植被动力学的时间空间的变化并且探索植被变化机制。在在不同时间规模的 EVI 和气候因素之间的关联在从 2001 ~ 2012 的一年的金海·莱克盆分别地为包括每月、季节、年度的规模的每个象素是计算的。这研究的主要目的是揭示什么时候,植被变化在哪儿并且为什么练习以便为明智的地区性的生态系统管理支持对全球变化以及有用信息和技术的陆上的反应的更好的理解。主要结论如下:(1 ) 在这个区域的全面植被 EVI 增加了 6% 在期间最近 12 年。在种季节的 EVI 价值(即春天和夏天) 展出了很重要的改善趋势,分别地占了 12.8% 和 9.3% 。EVI 的空间模式看明显的空间异质哪个与热水的状况一致。一般来说,自从将近 78% 象素整个盆显示出增加的趋势,植被范围在区域的大多数部分改善了,当仅仅在区域的小部分稍微降级了时。(2 ) EVI 变化断然与平均温度和降水被相关。一般来说在金海·莱克盆,降水是为植被生长的主导的开车因素;然而,在不同时间规模,它到植被的重量有差别。(3 ) 基于 geo 统计的分析,秋天降水在整个区域与下一春天 EVI 价值有强壮的关联。这调查结果探索秋天降水是重要指示物,然后,限制下个弹簧的植物生长。 | GUO Weit NI Xiangnan JING Duanyang LI Shuheng | 2014 | Journal of Geographical Sciences2014，24，6： | 6 |
| 2 | Research Progress of Bioactive Substances and Processing of Abelmoschus esculentus L.显示文摘Okra( Abelmoschus esculentus L.) is a novel healthcare vegetable that has been developed rapidly in recent years in China.It contains abundant bioactive substances with significant healthcare functions.So far,many domestic research institutions have carried out researches about the extraction technology of bioactive substances and their healthcare functions.At present,tender pods and other organs of A.esculentus are mainly used freshly and directly,but rare products have been processed and developed.In this paper,the research progress of bioactive substances and processing of A.esculentus was summarized,aiming at providing reference for the deep processing and comprehensive utilization of A.esculentus in the future in China. | Weiting WANG Xu GUO Chao LIU Jinyue SUN | 2016 | Agricultural Biotechnology2016，5，5： | 1 |
| 3 | Toughening Effects through Optimizing Cell Structure and Deformation Behaviors of Al–Mg Foams显示文摘As widely used protective materials,the application of Al foams is still limited by their low intrinsic mechanical properties caused by the brittleness of struts.The introduction of Mg is recently demonstrated effective to improve the mechanical performance of Al foams;however,the mechanism of Mg modification is still not clear.In this work,Al-Mg foams are developed through a powder metallurgy process with excellent compression performance and high energy absorption capacity.The effects of Mg modification on the cell structure,toughness,and deformation behavior are investigated systematically.As a result,the small cell size of~1.8 mm and the high sphericity of 0.92 are achieved with 5% of Mg addition,delivering high compression stress of 8.5±0.43 MPa and energy absorption capacity of 6.9±0.36 MJ/m^(3),simultaneously.The synergistic mechanism for the improved mechanical performance is also demonstrated to be the combination of stress transfer and plastic deformation behavior of cells.The results provide a new strategy to develop high-performance foam materials by improving toughness and further promote the practical application. | Hao Yu Xudong Yang Weiting Li Xudong Rong Siyuan Guo Lishi Ma Lizhuang Yang Junwei Sha Naiqin Zhao | 2022 | Acta Metallurgica Sinica(English Letters)2022，35，12： | 1 |
| 4 | Preparation of Ionic Liquids Immobilized on FMIL-101 Catalysts for Conversion of CO_(2)to Propylene Carbonate显示文摘Metal-organic frameworks(MOFs)have attracted considerable research attention as a new type of porous material for catalytic applications.Herein,2,5-dihydroxyterephthalic acid was proposed to replace conventional terephthalic acid and reacted with chromic nitrate nonahydrate to synthesize a functional metal–organic framework(FMIL-101).This was then used to immobilize various compound ionic liquids to prepare three ionic liquids immobilized on FMIL-101 catalysts,namely,FMIL-101-[HeMIM]Cl/(ZnBr_(2))_(2),FMIL-101-[CeMIM]Cl/(ZnBr_(2))_(2),and FMIL-101-[AeMIM]Br/(ZnBr_(2))_(2).After characterization by Fourier-transform infrared spectroscopy,X-ray diffraction,ultraviolet spectroscopy,thermogravimetry,specific surface area analysis,and scanning electron microscopy,the catalysts were used to mediate cycloaddition reactions between carbon dioxide(CO_(2))and propylene oxide.The effects of reaction temperature,reaction pressure,reaction time,and catalyst dosage on the catalytic performance were investigated.The results revealed that the FMIL-101-supported CIL catalysts afforded the target product propylene carbonate with good catalytic performance and thermal stability.The optimal catalyst,FMIL-101-[CeMIM]Cl/(ZnBr_(2))_(2),displayed a propylene oxide conversion of 98.64%and a propylene carbonate selectivity of 96.63%at a reaction temperature of 110℃,a reaction pressure of 2.0 MPa,a catalyst dosage of 2.0%relative to propylene oxide,and a reaction time of 2.5 h.In addition,the conversion and selectivity of the catalyst decreased slightly after four cycles.Additionally,the catalyst decreased slightly in catalytic performance after being recycled four times. | Sun Wenjie Ran Weiting Guo Liying Song Xiaohui LüDonghao | 2023 | China Petroleum Processing & Petrochemical Technology2023，25，1： | 0 |
| 5 | A PD-L1-targeting chimeric switch receptor enhances efficacy of CAR-T cell for pleural and peritoneal metastasis显示文摘Pleural and peritoneal metastasis accompanied by malignant pleural effusion(MPE)or malignant ascites(MA)is frequent in patients with advanced solid tumors that originate from the lung,breast,gastrointestinal tract and ovary.Regional delivery of CAR-T cells represents a new strategy to control tumor dissemination in serous cavities.However,malignant effusions constitute an immune-suppressive environment that potentially induces CAR-T cell dysfunction.Here,we demonstrated that the anti-tumor cytotoxicity of conventional 2nd-generation CAR-T cells was significantly inhibited by both the cellular and non-cellular components of MPE/MA,which was primarily attributed to impaired CAR-T cell proliferation and cytokine production in MPE/MA environment.Interestingly,we found that PD-L1 was widely expressed on freshly-isolated MPE/MA cells.Based on this feature,a novel PD-L1-targeting chimeric switch receptor(PD-L1.BB CSR)was designed,which can bind to PD-L1,switching the inhibitory signal into an additional 4-1BB signal.When co-expressed with a 2nd-generation CAR,PD-L1.BB CSR-modified CAR-T cells displayed superior fitness and enhanced functions in both culture medium and MPE/MA environment,causing rapid and durable eradication of pleural and peritoneal metastatic tumors in xenograft models.Further investigations revealed elevated expressions of T-cell activation,proliferation,and cytotoxicity-related genes,and we confirmed that PD-L1 scFv and 4-1BB intracellular domain,the two important components of PD-L1.BB CSR,were both necessary for the functional improvements of CAR-T cells.Overall,our study shed light on the clinical application of PD-L1.BB CSR-modified dual-targeting CAR-T cells.Based on this study,a phase I clinical trial was initiated in patients with pleural or peritoneal metastasis(NCT04684459). | Qizhi Ma Xia He Benxia Zhang Fuchun Guo Xuejin Ou Qiyu Yang Pei Shu Yue Chen Kai Li Ge Gao Yajuan Zhu Diyuan Qin Jie Tang Xiaoyu Li Meng Jing Jian Zhao Zeming Mo Ning Liu Yao Zeng Kexun Zhou Mingyang Feng Weiting Liao Wanting Lei Qiu Li Dan Li Yongsheng Wang | 2022 | Signal Transduction and Targeted Therapy2022，7，12： | 0 |
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