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| 1 | Neuroimaging the brain-gut axis in patients with irritable bowel syndrome显示文摘AIM:To summarize and synthesize current literature on neuroimaging the brain-gut axis in patients with irritable bowel syndrome(IBS).METHODS:A database search for relevant literature was conducted using Pub Med,Scopus and Embase in February 2015.Date filters were applied from the year2009 and onward,and studies were limited to those written in the English language and those performed upon human subjects.The initial search yielded 797articles,out of which 38 were pulled for full text review and 27 were included for study analysis.Investigations were reviewed to determine study design,methodology and results,and data points were placed in tabular format to facilitate analysis of study findings across disparate investigations.RESULTS:Analysis of study data resulted in the abstraction of four key themes:Neurohormonal differences,anatomic measurements of brain structure and connectivity,differences in functional responsiveness of the brain during rectal distention,and confounding/correlating patient factors.Studies in this review noted alterations of glutamate in the left hippocampus(HIPP),commonalities across IBS subjects in terms of brain oscillation patterns,cortical thickness/gray matter volume differences,and neuroanatomical regions withincreased activation in patients with IBS:Anterio cingulate cortex,mid cingulate cortex,amygdala anterior insula,posterior insula and prefrontal cortex.A striking finding among interventions was the substantia influence that patient variables(e.g.,sex,psychologica and disease related factors)had upon the identification of neuroanatomical differences in structure and con nectivity.CONCLUSION:The field of neuroimaging can provide insight into underlying physiological differences that distinguish patients with IBS from a healthy population. | Kristen R Weaver Lee Anne B Sherwin Brian Walitt Gail D'Eramo Melkus Wendy A Henderson | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，2： | 8 |
| 2 | Late relapses in patients successfully treated for thrombotic thrembocytopenic purpura显示文摘 | Kenneth H S Gail A R Rama C | 1995 | Ann Intern Med1995，122，8： | 1 |
| 3 | Analysis of a model of the nutrient driven self-cycling fermentation process显示文摘 | Smith R J Wolkowicz Gail S K | 2004 | Dynamics of Continuous Discrete and Impulsive Systems Series B2004，11，2： | 1 |
| 4 | Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement显示文摘 | Evanthia Diamanti-Kandarakis Jean-Pierre Bourguignon Linda C. Giudice Russ Hauser Gail S. Prins Ana M. Soto R Thomas Zoeller Andrea C. Gore | 2009 | Endocrine Reviews2009，，4： | 1 |
| 5 | Haplotype analysis in population genetics and association studies显示文摘 | ZHAO Hongyu PFEIFFER R GAIL M H | 2003 | Pharmacogenomics2003，4，2： | 1 |
| 6 | Isolation of a pluripotential cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells显示文摘 | Gail R M | 1981 | Proc Natl Acad Sci USA1981，78，12： | 1 |
| 7 | Molecular genetic tools to infer the origin of forest plants and wood显示文摘 | Finkeldey R Leinemann L Gailing O | 2010 | Appl Microbiol Biotechnol2010，85，5： | 1 |
| 8 | Reproducibility studies and interlaboratory concordance for assays of serum hormone levels: estrone, estradiol, estrone sulfate, and progesterone 显示文摘 | Gail M H Fears T R Hoover R N | 1996 | Cancer Epidemical Biomarkers Prev1996，5，： | 1 |
| 9 | Genetic structure of plantations and the conservation of genetic resources of Brazilian pine(Araucaria angustifolia)显示文摘 | Stefenon VM Gailing O Finkeldey R | | 0，，： | 1 |
| 10 | Increasing breast cancer incidence in China: the numbers add up显示文摘 | Ziegler R G Anderson W F Gail M H | 2008 | J Natl Cancer Inst2008，100，19： | 1 |
| 11 | A Longitudinal study of psychological adjustment to familial genetic risk assessment for ovarian cancer显示文摘 | Paul R Gail R Jane I | 1999 | Gynecol Oncol1999，74，3： | 1 |
| 12 | Reproducibility studies and interlaboratory concordance for assays of serum hormone levels: estrone, estradiol, estrone sulfate, and progesterone 显示文摘 | Gail M H Fears T R Hoover R N | 1996 | Cancer Epidemical Biomarkers Prev1996，5，： | 1 |
| 13 | Sinus tympani : anatomic considerations, computed tomography, and a discussion of the retrofacial approach for removal of disease 显示文摘 | PICKETT B P GAIL W S LAMBERT P R | 1995 | Am J Otol1995，16，6： | 1 |
| 14 | Genomic pro?filing of myeloid sarcoma by array comparative ge?nomic hybridization显示文摘 | DEEB G BAER M R GAILE D P | 2005 | Genes Chromosomes Cancer2005，44，： | 1 |
| 15 | Neural mechanisms of visual associative processing显示文摘 | Eckhorn R Gail A Bruns A | 2004 | Acta Neurobiol Exp2004，64，2： | 1 |
| 16 | Unsedated ultrathin EGD is well accepted when compared with conventional sedated EGD: a multicenter randomized trial显示文摘 | Ruel T Garcia John P Cello Mindie H Nguyen Stanley J Rogers Alex Rodas Huy N Trinh Neil H Stollman Gail Schlueck Kenneth R McQuaid | 2003 | Gastroenterology2003，，6： | 1 |
| 17 | Patterns of contempora-ry hybridization inferred from paternity analysis in a four-oak-species forest显示文摘 | Curtu A Gailing O Finkeldey R | 2009 | BMC Evolutionary Biology2009，9，1： | 1 |
| 18 | Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial显示文摘 | Kathy S Albain R Suzanne Swann Valerie W Rusch Andrew T Turrisi Frances A Shepherd Colum Smith Yuhchyau Chen Robert B Livingston Richard H Feins David R Gandara Willard A Fry Gail Darling David H Johnson Mark R Green Robert C Miller Joanne Ley Willliam T | 2009 | The Lancet . 2009 (9687)2009，，9687： | 1 |
| 19 | Increasing breast cancer incidence in China:The numbers add up显示文摘 | Ziegler R G Anderson W F Gail M H | 2008 | Journal of the National Cancer Institute2008，100，19： | 1 |
| 20 | Molecular genetic tools to infer the origin of forest plants and wood显示文摘 | Finkeldey R Leinemann L Gailing O | 2010 | Ap- plied Microbiology and Biotechnology2010，85，5： | 1 |
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