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| 1 | Sex differences in cognitive impairment in Alzheimer's disease显示文摘Sex differences in neurocognitive abilities have been extensively explored both in the healthy population andin many disorders. Until recently, however, little work has examined such differences in people with Alzheimer's disease(AD). This is despite clear evidence that AD is more prevalent in women, and converging lines of evidence from brain imaging, post-mortem analyses, hormone therapy and genetics suggesting that AD affects men and women differently. We provide an overview of evidence attesting to the poorer cognitive profiles in women than in men at the same stage of AD. Indeed, men significantly outperform women in several cognitive domains, including: Language and semantic abilities, visuospatial abilities and episodic memory. These differences do not appear to be attributable to any differences in age, education, or dementia severity. Reasons posited for this female disadvantage include a reduction of estrogen in postmenopausal women, greater cognitive reserve in men, and the influence of the apolipoprotein E ε4 allele. Assessment of cognitive abilities contributes to the diagnosis of the condition and thus, it is crucial to identify the role of sex differences if potentially more accurate diagnoses and treatments are to emerge. | Keith R Laws Karen Irvine Tim M Gale | 2016 | World Journal of Psychiatry2016，6，1： | 18 |
| 2 | The impact of FLT3 intenaal tandem duplication mutant level, number, size,and interaction with NPM1 mutations in a large co- hort of young adult patients with acute myeloid leukemia 显示文摘 | GALE R E GREEN C ALLEN C | 2008 | Blood2008，111，： | 1 |
| 3 | Missed opportunities for sexually transmitted disease, human immunodeficiency virus, and pregnancy prevention services during adolescent health supervision visits 显示文摘 | Gale R B Richard L Richard L | 2003 | Pediatric2003，111，： | 1 |
| 4 | Simple sequence repeat(SSR)marker survey of the cassava(Manihot esculenta Crantz)genome:toward a SSR-based molecular genetic map of cassava显示文摘 | Mba R E C Stephenson P Edwards K Mezer S Nkumbira J Gulberg U Apel K Gale M Tohme J Fregene M A | | 0，，： | 1 |
| 5 | Klebsiella pneumoniae Carbapenemase-Producing Klebsiella Pneumoniae in the Intensive Care Unit: A Real Challenge to Physicians, Scientific Community, and Society显示文摘 | Carvalhaes CG Cay R Gales AC | 2013 | Shock2013，39，71： | 1 |
| 6 | 'Perfect' markers for the Rht-Blb and Rht-Dlb dwarfing genes in wheat 显示文摘 | Ellis H Spielmeyer W Gale R | 2002 | Theoretical and Applied Genetics2002，105，67： | 1 |
| 7 | Sandy fields tradilional farming for water conservation in China 显示文摘 | WILLIAM J GALE R W MCCOLL | 1993 | Journal of Soil and Water Conservalion1993，48，： | 1 |
| 8 | Survival of the fittest? Natural selection in islet transplantation显示文摘 | SMITH R M GALE E A M | 2005 | Transplantation2005，79，10： | 1 |
| 9 | Chemical and thermal expansion of calcium-doped lanthanum chromite 显示文摘 | Williford R E Armstfong T R Gale J D | 2000 | Journal of Snlid State Chemistry2000，149，2： | 1 |
| 10 | Natural fractures in the Barnett shale and their importance for hydraulic fracture treatments显示文摘 | Gale J F W Reed R M Holder J | 2007 | AAPG Bulletin2007，91，4： | 1 |
| 11 | Some pitfalls in wood identification,with reference to Nothofagus显示文摘 | GALE R | 1982 | IAWA Bulletin1982，3，： | 1 |
| 12 | An investigation of oxidative stress and antioxidant biomarkers during greenshell mussel (Perna canaliculus) oocyte cryopreservation显示文摘 | Gale S L Burritt D J Tervit H R | 2014 | The- riogenology2014，82，6： | 1 |
| 13 | Phosphorus retention by wetland soils used for treated wastewater disposal显示文摘 | Gale P M Reddy K R Graetz D A 1994 | 1994 | J Environ Qual1994，23，： | 1 |
| 14 | Phosphorus sorption capacities of wetland soils and stream sediments impacted by dairy effluent显示文摘 | Reddy K R O'Connor G A Gale P M | 1998 | J Environ Qual1998，27，： | 1 |
| 15 | Acute myeloid leukae- mia blast cells with a tyrosine kinase domain mutation of FLT3 are less sensitive to lestaurtinib than those with a FLT3 internal tan- dem duplication显示文摘 | Mead A J Gale R E Kottaridis P D etal | 2008 | Br J Haematol2008，141，14： | 1 |
| 16 | Use of the semipermeable membrane device as an in situ sampler of waterborne bioavailable PCDD and PCDF residues at sub-parts-per-quadrillion concentrations显示文摘 | Lebo J A Gale R W Petty J D | 1995 | Environ Sci Teehnol1995，29，11： | 1 |
| 17 | Perfect markers for the Rht-B1b and Rht-D1b dwarfing genes in wheat显示文摘 | Ellis M H Spielmeyer W Gale R | | 0，，： | 1 |
| 18 | Theoretical and experimental investigations on the morphology of pharmaceutical crystals显示文摘 | Coombes D S Catlow C R A Gale J D | 2002 | J Pharm Sci2002，91，： | 1 |
| 19 | Environmental management accounting as a re- flexive modernization strategy in cleaner production显示文摘 | Gale R | 2006 | Journal of Cleaner Production2006，14，14： | 1 |
| 20 | An interatomic potential study of the properties of gallium nitride 显示文摘 | ZAPOL P PANDEY R GALE J D | 1997 | J Phys Condens Matter1997，9，： | 1 |
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