5篇
您的检索式：作者名="Gary Frost"
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| 1 | Effect of nutritional counselling on hepatic,muscle and adipose tissue fat content and distribution in non-alcoholic fatty liver disease显示文摘AIM: To assess the effectiveness of the current UK clinical practice in reducing hepatic fat (IHCL). METHODS: Whole body MRI and 1H MRS were obtained, before and after 6 mo nutritional counselling, from liver, soleus and tibialis muscles in 10 subjects with non-alcoholic fatty liver disease (NAFLD). RESULTS: A 500 Kcal-restricted diet resulted in an average weight loss of 4% (-3.4 kg,) accompanied by significant reductions in most adipose tissue (AT) depots, including subcutaneous (-9.9%), abdominal subcutaneous (-10.2%) and intra-abdominal-AT (-11.4%). Intramyocellular lipids (IMCL) were significantly reduced in the tibialis muscle (-28.2%). Decreases in both IHCL (-39.9%) and soleus IMCL (-12.2%) content were also observed, although these were not significant. Several individuals showed dramatic decreases in IHCL, while others paradoxically showed increases in IHCL content. Changes in body composition were accompanied by improvements in certain liver function tests: serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT). Significant correlations were found between decreases in IHCL and reductions in both intra-abdominal and abdominal subcutaneous AT. Improvements in liver function tests were associated with reductions in intra-abdominal AT, but not with changes in IHCL. CONCLUSION: This study shows that even a very modest reduction in body weight achieved through lifestyle modification can result in changes in body fat depots and improvements in LFTs. | E Louise Thomas Audrey E Brynes Gavin Hamilton Nayna Patel Adam Spong Robert D Goldin Gary Frost Jimmy D Bell Simon D Taylor-Robinson | 2006 | World Journal of Gastroenterology2006，12，36： | 13 |
| 2 | Oxyntomodulin Suppresses Appetite and Reduces Food Intake in Humans显示文摘 | Mark A. Cohen Sandra M. Ellis Carel W. Le Roux Rachel L. Batterham Adrian Park Michael Patterson Gary S. Frost Mohammad A. Ghatei Stephen R. Bloom | 2003 | The Journal of Clinical Endocrinology & Metabolism2003，，10： | 1 |
| 3 | Neural adaptation to resistive exercise-mechanism and recom- mendations for training practices显示文摘 | David A Gabriel Gary Kamen Gail Frost | 2006 | Sports Med2006，36，2： | 1 |
| 4 | Ghrelin Increases Energy Intake in Cancer Patients with Impaired Appetite: Acute, Randomized, Placebo-Controlled Trial显示文摘 | Nicola M. Neary Caroline J. Small Alison M. Wren Jennifer L. Lee Maralyn R. Druce Carlo Palmieri Gary S. Frost Mohammad A. Ghatei R Charles Coombes Stephen R. Bloom | 2004 | The Journal of Clinical Endocrinology & Metabolism2004，，6： | 1 |
| 5 | Relation of plasma leptin concentrations to sex, body fat, dietary intake, and peak oxygen uptake in young adult women and men显示文摘 | Gary D Miller PhD Rebecca Frost BS | 2001 | Nutrition2001，17，： | 1 |
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