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| 1 | Imaging of bone metastasis: An update显示文摘Early detection of skeletal metastasis is critical for accurate staging and optimal treatment. This paper briefly reviews our current understanding of the biological mechanisms through which tumours metastasise to bone and describes the available imaging methods to diagnose bone metastasis and monitor response to treatment. Among the various imaging modalities currently available for imaging skeletal metastasis, hybrid techniques whichfuse morphological and functional data are the most sensitive and specific, and positron emission tomography(PET)/computed tomography and PET/magnetic resonance imaging will almost certainly continue to evolve and become increasingly important in this regard. | Gerard J O'Sullivan Fiona L Carty Carmel G Cronin | 2015 | World Journal of Radiology2015，7，8： | 10 |
| 2 | Re-challenge chemotherapy with gemcitabine plus carboplatin in patients with non-small cell lung cancer显示文摘Despite recent improvements to current therapies and the emergence of novel agents to manage advanced non-small cell lung cancer(NSCLC),the patients′overall survival remains poor.Re-challenging with first-line chemotherapy upon relapse is common in the management of small cell lung cancer but is not well reported for advanced NSCLC.NSCLC relapse has been attributed to acquired drug resistance,but the repopulation of sensitive clones may also play a role,in which case re-challenge may be appropriate.Here,we report the results of re-challenge with gemcitabine plus carboplatin in 22 patients from a single institution who had previously received gemcitabine plus platinum in the first-line setting and had either partial response or a progression-free interval of longer than 6 months.In this retrospective study,the charts of patients who underwent second-line chemotherapy for NSCLC in our cancer center between January 2005 and April 2010 were reviewed.All the patients who received a combination of gemcitabine and carboplatin for re-challenge were included in the study.These patients were offered second-line treatment on confirmation of clear radiological disease progression.The overall response rate was 15%and disease control rate was 75%.The median survival time was 10.4 months,with 46%of patients alive at 1 year.These results suggest that re-challenge chemotherapy should be considered in selected patients with radiological partial response or a progression-free survival of longer than 6 months to the initial therapy. | Khurum Khan Gerard G Hanna Lynn Campbell Paula Scullin Adnan Hussain Ruth L Eakin Jonathan McAleese | 2013 | Chinese Journal of Cancer2013，32，10： | 3 |
| 3 | Performance, structure, and mechanism of CeO 2 in HCl oxidation to Cl 2显示文摘 | Amol P. Amrute Cecilia Mondelli Maximilian Moser Gerard Novell-Leruth Núria López Dirk Rosenthal Ramzi Farra Manfred E. Schuster Detre Teschner Timm Schmidt Javier Pérez-Ramírez | 2011 | Journal of Catalysis2011，，： | 2 |
| 4 | Symptomatic hyperlaetataemia: an emerging complication of antiretroviral therapy 显示文摘 | Gerard Y Maulin L Yazdanpanah Y | 2000 | AIDS2000，14，17： | 1 |
| 5 | Seismic waves in stratified anisotropic media显示文摘 | Gerard J F Frazer L N | 1984 | Geophysical Journal of the Royal Astronomical Society1984，78，： | 1 |
| 6 | Sleep apnea in patientsreceiving growth hormone显示文摘 | Gerard JM Garibaldi L Myers SE | 1997 | Clin Pediatr Phila1997，36，6： | 1 |
| 7 | Nonlinear acoustic echo cancellation based on volterra filters 显示文摘 | G Alexandre F Gerard L B J Regine | 2003 | IEEE Transactions on Speech and Audio Processing2003，11，6： | 1 |
| 8 | A Randomized Controlled Trial in Second-Generation Zotarolimus-Eluting Resolute Stents Versus Everolimus-Eluting Xience V Stents in Real-World Patients显示文摘 | Clemens von Birgelen Mounir W.Z. Basalus Kenneth Tandjung K. Gert van Houwelingen Martin G. Stoel J.(Hans) W. Louwerenburg Gerard C.M. Linssen Salah A.M. Sa?d Miep A.W.J. Kleijne Hanim Sen Marije M. L?wik Job van der Palen Patrick M.J. Verhorst Frits H.A. | 2012 | Journal of the American College of Cardiology2012，，15： | 1 |
| 9 | Seismic waves in stratified anisotropic media显示文摘 | Gerard J F Frazer L N | 1987 | Geophysical Journal of the Royal Astronomieal Society1987，91，： | 1 |
| 10 | AAISafeR limits ventricular pacing in unselected patients 显示文摘 | Guy P Gerard L Remi N | 2007 | PACE2007，30，： | 1 |
| 11 | Mechanisms of reduced and compensatory growth 显示文摘 | HORNICK J L VAN EENAEME C GERARD O | 2000 | Domestic Animal Endocrinology2000，19，： | 1 |
| 12 | Prospectivestudy of rituximab in chemotherapy-dependent humanimmunodeficiency virus associated multicentric Castle-man's disease: ANRS 117 CastlemaB Trial显示文摘 | Gerard L Berezne A Galicier L | 2007 | J ClinOncol2007，25，： | 1 |
| 13 | Adenovirus-mediated expression of tissue factor pathway inhibitor-2 inhibits endothelial cell migration and angiogenesis显示文摘 | Ivanciu L Gerard RD Tang H | 2007 | Arterioscler Thromb Vasc Biol2007，27，2： | 1 |
| 14 | Variable selection in multivariate calibration of a spectroscopic glucose sensor显示文摘 | Mcshane Michael J Cote Gerard L Spiegelman Clifford | 1997 | Applied Spectroscopy1997，51，10： | 1 |
| 15 | Nocturnal 02 onrichment of room air at high altitude increases daytime 02 Saturation without changing control of ventilation显示文摘 | Gerard A Powell F L | 2000 | High Alt Med Biol2000，1，3： | 1 |
| 16 | Structure analysis of PVA nanocomposites 显示文摘 | Kovarova L Kalendova A Gerard J F | 2005 | Macromolecular Symposium2005，221，： | 1 |
| 17 | Substrate and enzyme distribution in cells and eell fractions of the nervous system显示文摘 | Abood L G Gerard R W Tschirgi R D | 1952 | Am J Physiol1952，168，： | 1 |
| 18 | Guidance Algorithms Design: A Nonlinear Inverse Approach显示文摘 | | 1998 | Journal of Guidance Control and Dynamics1998，21，5： | 1 |
| 19 | Electrochemical and electrical properties of copper organic complexing films deposited on a platinum electrode显示文摘 | Minh C P Gerard T Pierre C L | 1980 | Electroanal Chem1980，111，： | 1 |
| 20 | Mutants of Eacherichia coli with high minimal temperatures of growth显示文摘 | Gerard A O'Donovan Catherine L | 1965 | Journal of Bacteriology1965，90，3： | 1 |
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