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| 1 | GIS在环保型养猪业区域规划中的应用显示文摘快速发展的养猪业在带来巨大社会效益和经济效益的同时也带来了许多环境问题,FAO从1998年开始启动了养殖业环境与发展项目,目的是为了在促进养殖业发展、增加经济效益的同时大幅度减少养殖业对环境的不利影响。该文是FAO项目中的一部分,主要是应用G IS技术工具,通过建立养猪业选址的指标体系,发展了可持续的畜牧业生产建设区域规划的决策辅助工具,以减少养猪业发展对环境带来的负面影响;并且将该技术在江西省的养猪大县万年县进行了具体的应用。 | 赵小敏 Gerrit J Carsjens Pierre Gerber | 2006 | 农业工程学报2006，22，9： | 12 |
| 2 | Role of E3 ubiquitin ligases in lung cancer显示文摘E3 ubiquitin ligases are a large family of proteins that catalyze the ubiquitination of many protein substrates for targeted degradation by the 26S proteasome.Therefore,E3 ubiquitin ligases play an essential role in a variety of biological processes including cell cycle regulation,proliferation and apoptosis.E3 ubiquitin ligases are often found overexpressed in human cancers,including lung cancer,and their deregulation has been shown to contribute to cancer development.However,the lack of specific inhibitors in clinical trials is a major issue in targeting E3 ubiquitin ligases with currently only one E3 ubiquitin ligase inhibitor being tested in the clinical setting.In this review,we focus on E3 ubiquitin ligases that have been found deregulated in lung cancer.Furthermore,we discuss the processes in which they are involved and evaluate them as potential anti-cancer targets.By better understanding the mechanisms by which E3 ubiquitin ligases regulate biological processes and their exact role in carcinogenesis,we can improve the development of specific E3 ubiquitin ligase inhibitors and pave the way for novel treatment strategies for cancer patients. | Barbara C Snoek Leonie HAM de Wilt Gerrit Jansen Godefridus J Peters | 2013 | World Journal of Clinical Oncology2013，4，3： | 5 |
| 3 | Definition of colorectal anastomotic leakage: A consensus survey among Dutch and Chinese colorectal surgeons显示文摘AIM To determine the level of consensus on the definition of colorectal anastomotic leakage(CAL) among Dutch and Chinese colorectal surgeons.METHODS Dutch and Chinese colorectal surgeons were asked to partake in an online questionnaire. Consensus in the online questionnaire was defined as > 80% agreement between respondents on various statements regarding a general definition of CAL,and regarding clinical and radiological diagnosis of the complication.RESULTS Fifty-nine Dutch and 202 Chinese dedicated colorectal surgeons participated in the online survey. Consensus was found on only one of the proposed elements of a general definition of CAL in both countries: ‘extravasation of contrast medium after rectal enema on a CT scan'. Another two were found relevant according to Dutch surgeons: ‘necrosis of the anastomosis found during reoperation',and ‘a radiological collection treated with percutaneous drainage'. No consensus was found for all other proposed elements that may be included in a general definition.CONCLUSION There is no universally accepted definition of CAL in the Netherlands and China. Diagnosis of CAL based on clinical manifestations remains a point of discussion in both countries. Dutch surgeons are more likely to report ‘subclinical' leaks as CAL,which partly explains the higher reported Dutch CAL rates. | Stefanus J van Rooijen Audrey CHM Jongen Zhou-qiao Wu Jia-fu Ji Gerrit D Slooter Rudi MH Roumen Nicole D Bouvy | 2017 | World Journal of Gastroenterology2017，23，33： | 4 |
| 4 | Retrospective analysis of old-age colitis in the Dutch inflammatory bowel disease population显示文摘AIM: To describe the characteristics of Dutch patients with chronic inflammatory bowel disease (IBD) first diagnosed above 60 years of age-a disease also known as old-age colitis (OAC) and to highlight a condition that has a similar appearance to IBD, namely segmen- tal colitis associated with diverticular disease (SCAD). METHODS: A retrospective longitudinal survey of patient demographic and clinical characteristics, disease characteristics, diagnostic methods, management and course of disease was performed. The median follow-up period was 10 years. RESULTS: Of a total of 1100 IBD patients attending the Department of Gastroenterology, 59 (5%) [median age 82 years (range 64-101); 25 male (42%)] were identified. These patients were diagnosed with ulcerative colitis (n = 37, 61%), Crohn’s disease (n = 14, 24%), and indeterminate colitis (n = 8, 15%). Remission was induced in 40 (68%) patients within a median interval of 6 mo (range 1-21) and immunosuppressive therapy was well tolerated. Histological evaluation based on many biopsy samples and the course of the disease led to other diagnosis, namely SCAD instead of IBD in five (8%) patients. CONCLUSION: OAC is not an infrequent problem for the gastroenterologist, and should be considered in the evaluation of older patients with clinical featuressuggestive of IBD. Extra awareness and extensive biopsy sampling are required in order to avoid an erroneous diagnosis purely based on histological mimicry of changes seen in SCAD, when diagnosing IBD in the presence of diverticulosis coli. | Muhammed Hadithi Marcel Cazemier Gerrit A Meijer Elisabeth Bloemena Richel J Felt-Bersma Chris J Mulder Stephan GM Meuwissen Amado Salvador Pea Adriaan A van Bodegraven | 2008 | World Journal of Gastroenterology2008，14，20： | 3 |
| 5 | Postprandial blood hormone and metabolite concentrations influenced by feeding frequency and feeding level in veal calves显示文摘 | VICARI T VAN DEN BORNE J J G C GERRITS W J J | 2008 | Domestic Animal Endocrinology2008，34，： | 1 |
| 6 | A High-Tc 4-bit periodic threshold analog-to-digital converter显示文摘 | Gerrit J Gerritsma Martin A J | 1997 | IEEE Transaction on Applied Superconductivity1997，7，2： | 1 |
| 7 | Accuracy and reliability of facial soft tissue depth measurements using cone beam computer tomography显示文摘 | Fourie Z Damstra J Gerrits PO | | 0，，1： | 1 |
| 8 | Ultrasound ex- amination of pathological cervical lymph nodes in patients with non-Hodgkin' s lymphoma and Hodgkin' s disease 显示文摘 | Gerrits C J van Overhagen H van Lore K | 1994 | Br J Haematol1994，88，3： | 1 |
| 9 | Ovarian response of the hypophysectomized pig to pregnant mare' s serum gonadotropin 显示文摘 | Kraeling RR Davis B J Gerrits RJ | 1974 | Biol Reprod1974，10，1： | 1 |
| 10 | Effect of protein and protein-free energy intake on protein and fat deposition rates in preruminant calves of 80 to 240 kg live weight显示文摘 | Gerrits W J Tolman G H Schrama J W | 1996 | Journal of Animal Scienc1996，74，： | 1 |
| 11 | Sucrose Metabolism in Plastids 显示文摘 | Nathalie Gerrits Stefan C H J Turk Kees P M van Dun | 2001 | Plant Physiology2001，125，2： | 1 |
| 12 | Principles and limitations of ultrmwideband FM communications systems显示文摘 | GERRITS J F M KOUWENHOVEN M H L VAN DER MEER P R | 2005 | EURASIP J Appl Sign Process2005，3，： | 1 |
| 13 | Perspectives for Artificial Insemination and Genomics to Improve Global Swine Populations显示文摘 | Gerrits R J Lunney J K~lohnson L A | 2005 | Theriogenology2005，63，2： | 1 |
| 14 | Inoculation of Scytalidium thermophilum in button mushroom compost and its effect on yield 显示文摘 | Straatsma G Olijnsma T W Gerrits J P G | 1994 | Applied and Environmental Microbiology1994，60，： | 1 |
| 15 | Effect of intake of linoleic acid and a - linolenic acid levels on con- version into long - chain polyunsaturated fatty acids in backfat and in intramuscular fat of growing pigs 显示文摘 | SMINK W VERSTEGEN M W GERRITS W J | 2013 | J Anim Physiol Anim Nutr2013，97，3： | 1 |
| 16 | Trends in composting 显示文摘 | Gerrits J P G | 1992 | Mushroom1992，508，： | 1 |
| 17 | Physio-logical increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells显示文摘 | MacLellan J D Gerrits M F Gowing A | 2005 | Diabetes2005，54，8： | 1 |
| 18 | New developments in indoor composting (tunnel process) 显示文摘 | Gerrits J P G | 1990 | Mushroom1990，205，： | 1 |
| 19 | A randomized comparison of sirolimus-eluting stent implantation with zotarolimus-eluting stent implantation for the treatment of total coronary occlusions: Rationale and design of the primary stenting of occluded native coronary arteries Ⅲ( PRISON Ⅲ) study 显示文摘 | Maarten J Suttorp Gerrit J Laarman | 2007 | American Heart Journal2007，154，3： | 1 |
| 20 | A GIS-based support tool for sustain- able spatial planning in metropolitan areas显示文摘 | Gerrit J C Arend L | 2007 | Landscape and Urban Planning2007，80，2： | 1 |
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