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| 1 | Adhesive small bowel adhesions obstruction: Evolutions in diagnosis, management and prevention显示文摘Intra-abdominal adhesions following abdominal surgery represent a major unsolved problem. They are the first cause of small bowel obstruction. Diagnosis is based on clinical evaluation, water-soluble contrast followthrough and computed tomography scan. For patients presenting no signs of strangulation, peritonitis or severe intestinal impairment there is good evidence to support non-operative management. Open surgery is the preferred method for the surgical treatment of adhesive small bowel obstruction, in case of suspected strangulation or after failed conservative management, but laparoscopy is gaining widespread acceptance especially in selected group of patients. 'Good' surgical technique and anti-adhesive barriers are the main current concepts of adhesion prevention. We discuss current knowledge in modern diagnosis and evolving strategies for management and prevention that are leading to stratified care for patients. | Fausto Catena Salomone Di Saverio Federico Coccolini Luca Ansaloni Belinda De Simone Massimo Sartelli Harry Van Goor | 2016 | World Journal of Gastrointestinal Surgery2016，8，3： | 28 |
| 2 | Systematic mechanism-orientated approach to chronic pancreatitis pain显示文摘Pain in chronic pancreatitis(CP) shows similarities with other visceral pain syndromes(i.e.,inflammatory bowel disease and esophagitis),which should thus be managed in a similar fashion.Typical causes of CP pain include increased intrapancreatic pressure,pancreatic inflammation and pancreatic/extrapancreatic complications.Unfortunately,CP pain continues to be a major clinical challenge.It is recognized that ongoing pain may induce altered central pain processing,e.g.,central sensitization or pro-nociceptive pain modulation.When this is present conventional pain treatment targeting the nociceptive focus,e.g.,opioid analgesia or surgical/endoscopic intervention,often fails even if technically successful.If central nervous system pain processing is altered,specific treatment targeting these changes should be instituted(e.g.,gabapentinoids,ketamine or tricyclic antidepressants).Suitable tools are now available to make altered central processing visible,including quantitative sensory testing,electroencephalograpy and(functional) magnetic resonance imaging.These techniques are potentially clinically useful diagnostic tools to analyze central pain processing and thus define optimum management approaches for pain in CP and other visceral pain syndromes.The present review proposes a systematic mechanism-orientated approach to pain management in CP based on a holistic view of the mechanisms involved.Future research should address the circumstances under which central nervous system pain processing changes in CP,and how this is influenced by ongoing nociceptive input and therapies.Thus we hope to predict which patients are at risk for developing chronic pain or not responding to therapy,leading to improved treatment of chronic pain in CP and other visceral pain disorders. | Stefan AW Bouwense Marjan de Vries Luuk TW Schreuder Soren S Olesen Jens B Frokjær Asbjorn M Drewes Harry van Goor Oliver HG Wilder-Smith | 2015 | World Journal of Gastroenterology2015，21，1： | 6 |
| 3 | Altered central pain processing after pancreatic surgery for chronic pancreatitis显示文摘 | S. A. Bouwense U. Ahmed Ali R. P. ten Broek Y. Issa C. H. van Eijck O. H. Wilder‐Smith H. van Goor | 2013 | Br J Surg2013，，13： | 3 |
| 4 | Early Endoscopic Retrograde Cholangiopancreatography in Predicted Severe Acute Biliary Pancreatitis: A Prospective Multicenter Study显示文摘 | Hjalmar C. van Santvoort Marc G. Besselink Annemarie C. de Vries Marja A. Boermeester Kathelijn Fischer Thomas L. Bollen Geert A. Cirkel Alexander F. Schaapherder Vincent B. Nieuwenhuijs Harry van Goor Cees H. Dejong Casper H. van Eijck Ben J. Witteman Ba | 2009 | Annals of Surgery2009，，1： | 2 |
| 5 | Pathophysiology of intraabdominal adhesion and abscess formation, and the effect of hyalumnan显示文摘 | Reijnen MM Bleichrodt RP van Goor H | 2003 | BrJ Surg2003，90，5： | 1 |
| 6 | Correction of the F508del- CFTR protein processing defectin vitro by the investigational drug VX-809 显示文摘 | Van Goor F Hadida S Grootenhuis P D | 2011 | Proc Natl Acad Sci U S A2011，108，18： | 1 |
| 7 | Interactions between signaling pathways in mediating GnRH-stimulated GTH release from goldfish pituitary cells:protein kinase C,but not cyclic AMP is an important mediator of GnRH-stimulated gonadotropin secretion in goldfish显示文摘 | Jobin R M Van Goor F Neumann C M | | 0，，： | 1 |
| 8 | PET-CT of extranodallymphoma显示文摘 | Metser U Goor O Lerman H | 2004 | AJR Am J Roentgenol2004，182，6： | 1 |
| 9 | Macrophage diversity in renalinjury and repaii显示文摘 | RicardoSD van Goor H Eddy AA | 2008 | J Clin Invest2008，118，11： | 1 |
| 10 | High functional levels of thrombin-activatable fibrinolysis inhibitor are associated with an increased risk of first ischemic stroke显示文摘 | GOOR MP GUIMARAES AH | 2005 | J Thromb Haemost2005，3，10： | 1 |
| 11 | A mutation in human keratin K6b produces a phenocopy of the K17 disorder pachyonychia congenita type 2显示文摘 | Smith FJ Jonkman MF van Goor H | 1998 | Hum Mol Genet1998，7，7： | 1 |
| 12 | The association of isolated mild fetal hydronephrosis with postnatal vesicourteral reflus显示文摘 | Goor JM Ramsey PS Oyburn PL Jr | 2002 | J Matern Fetal Neonatal2002，12，： | 1 |
| 13 | A new gene for pachyonychia congenitatype 2-Keratin K6B is the expression partner of K17 in epidermal appendages显示文摘 | McLean WHI Smith FJD van Goor H | 1998 | J Invest Dermatol1998，110，4： | 1 |
| 14 | The-148C/T fibrinogen gene polymorphism and fibrinogen oevels in ischaemic stroke:a case-control study显示文摘 | van Goor MP Gomez-Garcia EB Leebeek FW | 2004 | J Neurosurg Psychiatry2004，76，1： | 1 |
| 15 | Plasma homoeysteine is a risk faeor for recurrent vascular events in young patients with an ischacmic stroke or TIA显示文摘 | Bos MJ van Goor ML Koudstaal PJ | 2005 | J Neural2005，252，3： | 1 |
| 16 | ACE inhibitor use and the increased long - term risk of renal failure in diabetes显示文摘 | Hamming I Goor H Navis GJ | 2006 | Kidney Int2006，70，13： | 1 |
| 17 | γ-glutamyl transpeptidase from kidney bean fruit Ⅰ , Purification and Mechanism of action 显示文摘 | Moshe Y Goore John F Thompson | 1967 | Biochimica et Biophysica Acta1967，132，： | 1 |
| 18 | Patterns of axillary lymph node metastasis in breast cancer 显示文摘 | Van Lancker M Goor C Sacre R | 1995 | Am J Clin Oncol1995，18，3： | 1 |
| 19 | Myofibroblasts in experimental hydronephrosis 显示文摘 | Diamond JR van Goor H Ding G | 1995 | Am J Pathol1995，146，1： | 1 |
| 20 | Plasma homocysteine is a risk factor for recurrent vascular events in young patients with an ischemic stroke or TIA显示文摘 | Bos MJ van Goor ML Koudstal PJ | 2005 | J Neurol2005，252，： | 1 |
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