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1篇 您的检索式:作者名="Gregory L.Challis"
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1Synthesis of the C50 diastereomers of the C33–C51 fragment of stambomycin D显示文摘As products of genome mining,the stereochemical assignment of the macrolide antibiotics stambomycins A-D has been made on the basis of sequence analysis of the associated polyketide synthase,aside from two stereocentres at C28 and C50.Here we describe syntheses of the two C50 diastereomers of the C33-C51 region of the stambomycins,which support the PKS-based configurational assignment,and establish a strategy suitable for access to the extended stambomycin framework.Yongchen Wang Venkaiah Chintalapudi Haraldur G.Gudmundsson Gregory L.Challis Edward A.Anderson 2022Organic Chemistry Frontiers2022,9,2:0
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