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| 1 | 关于云南省瑞丽、畹町边境旅游情况的考察报告显示文摘关于云南省瑞丽、畹町边境旅游情况的考察报告AnInvestigationReportonBorderTravelinRuiliandHuantinofYunnanProvince￥byZhangGuangruiAbstract:China'spoli... | Zhang Guangrui | 1994 | 旅游学刊1994，9，4： | 11 |
| 2 | Application of Cellulose Nanofibril as a Wet-end Additive in Papermaking:A Brief Review显示文摘Recently,cellulose nanofibril(CNF)has emerged as a promising,sustainable reinforcement with outstanding potential in material science.Owing to the properties of CNF,it has been explored in food,cosmetic,and pharmaceutical applications,as well as in industrial applications such as paints,drill muds,packaging,and papermaking.The application of CNF in papermaking is expected to be implemented in the near future to broaden the commercial market of cellulose.Numerous studies and patents have reported on the manufacturing,properties,and applications of nanocellulose.This present paper focuses on the recent progresses in the application of CNF as a wet-end additive in papermaking. | Guihua Yang Guangrui Ma Ming He Xinxiang Ji Hye Jung Youn Hak Lae Lee Jiachuan Chen | 2020 | Paper And Biomaterials2020，5，2： | 9 |
| 3 | Effects of grain boundary ternary alloy doping on corrosion resistance of(Ce,Pr,Nd)-Fe-B permanent magnets显示文摘To satisfy the application of different environments,grain boundary doping is commonly used in the preparation of sintered magnets to improve the coercivity and the corrosion resistance.In this paper,the alloys were prepared by mixing different ratios of the master alloy(Ce,Pr,Nd)-Fe-B and the sintering aid(Pr,Nd)-Al.The coercivity of sintered(Ce,Pr,Nd)-Fe-B magnet is substantially enhanced by doping 2 wt%of(Pr,Nd)-Al,while the maximum energy product decreases slightly.We systematically investigated the corrosion behavior and micro structure of the sintered magnets in order to determine the mechanism of the degradation.The sintered(Ce,Pr,Nd)-Fe-B magnets with 2 wt% of(Pr,Nd)-Al addition exhibit the decreasing corrosion rate compared with others,due to the distribution of intergranular phases.The electrode potential difference between the main phase and the RE-rich phase is reduced by the addition of Al,improving the potential and stability of RE-rich phase due to the higher electrode potential of Al than that of Nd,Pr or Ce.In addition,the element distribution of the magnets doped by(Pr,Nd)-Al indicates that the Al-rich shell formed at the marginal area of the Ce-rich phase improves its stability.Therefo re,intergranular adding te rnary(Pr,Nd)-Al alloy powders results in both high coe rcivity and good corrosion resistance synchronously. | Xin Wang Minggang Zhu Feng Xi Meiling Zhang Fei Liu Yingjian Guo Lele Zhang Guangrui Zhang Wei Li | 2021 | Journal of Rare Earths2021，39，8： | 6 |
| 4 | Polyethyleneimine modified AuPd@PdAu alloy nanocrystals as advanced electrocatalysts towards the oxygen reduction reaction显示文摘Designing the low cost, active, durable, and alcohol-tolerant cathode catalysts towards the oxygen reduction reaction(ORR) is significant for the large-scale commercialization of direct alcohol fuel cells.Recently, Pd-based nanocrystals have attracted attention as Pt-alternative cathode catalysts towards the ORR in the alkaline electrolyte. Unfortunately, the pristine Pd-based nanocrystals lack the selectivity towards the ORR due to their inherent activity for the alcohol molecule oxidation reaction in the alkaline electrolyte. In this work, polyethyleneimine(PEI) modified Au Pd alloy nanocrystals with Au-rich Au Pd alloy cores and Pd-rich Pd Au alloy shells(AuPd@PdAu-PEI) are successfully synthesized using a traditional chemical reduction method in presence of PEI. The rotating disk electrode(RDE) technique is applied to evaluate the ORR performance of AuPd@PdAu-PEI nanocrystals. Compared with commercial Pd black,AuPd@PdAu-PEI nanocrystals show significantly enhanced activity and durability towards the ORR, and simultaneously exhibit particular alcohol tolerance towards the ORR in the alkaline electrolyte. | Qi Xue Guangrui Xu Rundong Mao Huimin Liu Jinghui Zeng Jiaxing Jiang Yu Chen | 2017 | Journal of Energy Chemistry2017，26，6： | 5 |
| 5 | Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB显示文摘Recent studies have suggested that transplant of hiPS-CMs is a promising approach for treating heart failure.However,the optimally clinical benefits have been hampered by the immature nature of the hiPS-CMs,and the hiPS-CMs-secreted proteins contributing to the repair of cardiomyocytes remain largely unidentified.Here,we established a saponin+compound optimally induced system to generate hiPS-CMs with stable functional attributes in vitro and transplanted in heart failure mice.Our study showed enhanced therapeutic effects of optimally induced hiPS-CMs by attenuating cardiac remodeling and dysfunction,these beneficial effects were concomitant with reduced cardiomyocytes death and increased angiogenesis.Moreover,the optimally induced hiPS-CMs could gathering to the injured heart and secret an abundant PDGF-BB.The reparative effect of the optimally induced hiPS-CMs in the hypoxia-injured HCMs was mimicked by PDGF-BB but inhibited by PDGF-BB neutralizing antibody,which was accompanied by the changed expression of p-PI3K and p-Akt proteins.It is highly possible that the PI3K/Akt pathway is regulated by the PDGF-BB secreted from the compound induced hiPS-CMs to achieve a longer lasting myocardial repair effect compared with the standard induced hiPS-CMs.Taken together,our data strongly implicate that the compound induced hiPS-CMs promote the recovery of injured hearts via paracrine action.In this process,the paracrine factor PDGF-BB derived from the compound induced hiPS-CMs reduces isoproterenol-induced adverse cardiac remodeling,which is associated with improved cardiac function,and these effects are mediated by the PI3K/Akt pathway,suggesting that the optimally induced hiPS-CMs may serve as a new promising cell therapy for clinical applications. | Hongmei Li Fenfang Wu Guangrui Huang Di Wu Ting Wang Xiashuang Wang Kai Wang Yuyin Feng Anlong Xu | 2022 | Signal Transduction and Targeted Therapy2022，7，8： | 2 |
| 6 | Influence of tanshinone on N-methyl-D-aspartate receptor 1 protein expression in a rat model of spinal cord ischemia/reperfusion injury显示文摘BACKGROUND: Tanshinone has been previously shown to be involved in the prevention and treatment of cerebral ischemia/reperfusion injury. In addition, excitatory amino acid-mediated neu- rotoxicity may induce neuronal damage following spinal cord ischemia/reperfusion injury. OBJECTIVE: To explore the interventional effect of tanshinone on N-methyl-D-aspartate receptor 1 (NMDAR1) protein expression in a rat model of spinal cord ischemia/reperfusion injury. DESIGN, TIME AND SETTING: A randomized molecular biology experiment was conducted at the Traumatology & Orthopedics Laboratory of Fujian Hospital of Traditional Chinese Medicine (Key Laboratory of State Administration of Traditional Chinese Medicine) between September 2007 and May 2008. MATERIALS: A total of 88 Sprague Dawley rats were randomly divided into a sham operation (n = 8), model (n = 40), and tanshinone (n = 40) groups. Thirty minutes after ischemia, rats in the model and tanshinone groups were observed at hour 0.5, 1, 4, 8, and 12 following perfusion, with eight rats for each time point. METHODS: Abdominal aorta occlusion was performed along the right renal arterial root using a Scoville-Lewis clamp to induce spinal cord ischemia. Blood flow was recovered 30 minutes following occlusion to establish models of spinal cord ischemia/reperfusion injury. Abdominal aorta occlusion was not performed in the sham operation group. An intraperitoneal injection of tanshinone ⅡA sul- fonic sodium solution (0.2 L/g) was administered to rats in the tanshinone group, preoperatively. In addition, rats in the sham operation and model groups were treated with an intraperitoneal injection of the same concentration of saline, preoperatively. MAIN OUTCOME MEASURES: NMDAR1 protein expression in the anterior horn of the spinal cord, accumulative absorbance, average absorbance, and area of positive cells were detected in the three groups through immunohistochemistry. RESULTS: All 88 rats were included in the final analysis. (1) NMDAR1 protein expression increased following 30-minute ischemia/1-hour reperfusion injury to the spinal cord, and reached a peak 4 hours after reperfusion. (2) Accumulative absorbance and average absorbance of NMDAR1, as well as area of positive cells in the model group, were significantly greater than the sham operation group at each time point (P < 0.05). However, values in the tanshinone group were significantly less than the model group (P < 0.05). CONCLUSION: NMDAR1 protein expression was rapidly increased following spinal cord ische- mia/reperfusion injury and reached a peak 4 hours following reperfusion. In addition, tanshinone downregulated NMDAR1 protein expression in the anterior horn of the spinal cord. | Li Zhang Xiang Lin Yong Fu Guangrui Nie Qiqing Zeng | 2009 | Neural Regeneration Research2009，4，1： | 2 |
| 7 | High-throughput RNA sequencing reveals the anti-inflammatory mechanism of baicalin on Propionibacterium acnes-induced acne in rabbits显示文摘Objective:Propionibacterium acnes(P.acnes)plays an important role in the development of acne,an inflammatory skin disease with a high-incidence.In this study,we used high-throughput RNA sequencing(RNA-seq)to reveal the anti-inflammatory mechanism of baicalin on P.acnes-induced acne in rabbits.Methods:The Kligman method was used to induce acne in the ears of New Zealand rabbits.The effect of baicalin on the acne model was evaluated by the number of acne lesions and hematoxylin and eosin(H&E)staining of acne tissues.Enzyme-linked immunoabsorbent assay was used to measure the protein expression levels of tumor necrosis factor a(TNFA),interleukin-1 b(IL1B),IL6,and IL8 in the serum of rabbits.RNA-seq was performed to investigate the mechanism of anti-inflammatory activities of baicalin on acne.Immunohistochemical analysis and Western blot were used to validate the expression levels of related proteins in acne tissues.Results:Baicalin treatment significantly reduced the number of acne lesions and lesions of the ear as well as levels of serum inflammatory cytokines.RNA-seq data showed that baicalin treatment globally suppressed inflammation,especially the TNF signaling pathway and Staphylococcus aureus infection pathway,in the rabbit acne model.Conclusion: Baicalin effectively ameliorates P. acnes-induced acne in rabbits by suppressingthe inflammatory response in rabbits. | Xingzhe Yang Guangrui Huang Leiming You Honghao Sheng Yuxiu Sun Yuyin Feng Qingyi Lu Anlong Xu | 2019 | Journal of Traditional Chinese Medical Sciences2019，6，3： | 2 |
| 8 | Measure Synchronization of High-cycle Islets in Couple Hamiltonian Sys- tems 显示文摘 | CHEN Shaoying WANG Guangrui CHEN Shigang | 2004 | Chin Phys Leu2004，21，11： | 1 |
| 9 | Increased calcium deposits and decreased Ca 2+ -ATPase in erythrocytes of ascitic broiler chickens显示文摘 | Kai Li Lihong Zhao Guangrui Geng Liqin Ma Shishan Dong Tong Xu Jianlin Wang Huiyu Wang Yong Tian Jian Qiao | 2010 | Research in Veterinary Science2010，，3： | 1 |
| 10 | Fecal-associated microbiome differences between traditional Chinese medicine qi-deficiency and balanced constitutions显示文摘Objective:To explore the structural and functional characteristics of the fecal-associated microbiome(FAM)in a traditional Chinese medicine(TCM)qi-deficiency constitution(QDC)by comparing with balanced constitution(BC)and screen the related biomarkers.Methods:In this cross-sectional study,the TCM constitutions of subjects were determined based on published the Classification and Determination of constitution in TCM and further confirmed by a TCM clinician.Clinical characteristics were recorded,and fecal samples were collected for 16S rDNA sequencing using the Illumina Miseq platform.The FAM structure was described using alpha-diversity indexes,beta-diversity indexes,and the relative abundances of the dominant taxa.Differences in the FAM distribution and function were analyzed with a Wilcoxon rank-sum test,MetagenomeSeq,and LEfSe analysis,after which a receiver operating characteristic curve based on the specific operational taxonomic units(OTUs)was constructed to calculate the area under the curve.Results:Our study population was composed of 22 BCs and 9 QDCs.There were no significant differences between the two groups in the distribution of clinical characteristics or alpha-diversity indexes,except for the sweets preference and blood glucose level.In principal coordinate analysis and partial least squares discriminant analysis,the bacterial communities in the BC group samples and QDC group samples clustered separately.Notably,there were 214 OTUs significantly distributed between groups in the MetagenomeSeq analysis,200 OTUs identified by the Wilcoxon rank-sum test,and 6 OTUs found by the LEfSe analysis.Predicted function analysis revealed that six metabolic pathways were distinctly distributed between the two groups.The area under the curve for the receiver operating characteristic curve based on the four specific OTUs was 0.88.Conclusion:Unique FAM structural and related functional characteristics are displayed in individuals with a QDC,and four specific OTUs could be used as QDC biomarkers to assist in clinical diagnosis. | Jianhua Zhen Pengfei Zhao Guangrui Huang Yini Li Lu Zhao Yuhang Zhang Anlong Xu | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，2： | 1 |
| 11 | Re- search on microstructure and magnetostriction of Fesa GalT- Dy~ alloys显示文摘 | Jiang Liping Zhang Guangrui Yang Jiandong | 2010 | J Rare Earth2010，28，： | 1 |
| 12 | IMMUNE RBF NETWORK AND ITS APPLICATION IN THE MODULATION-STYLE RECOGNITION OF RADAR SIGNALS显示文摘Based on Immune Programming(IP), a novel Radial Basis Function (RBF) networkdesigning method is proposed. Through extracting the preliminary knowledge about the widthof the basis function as the vaccine to form the immune operator, the algorithm reduces thesearching space of canonical algorithm and improves the convergence speed. The application ofthe RBF network trained with the algorithm in the modulation-style recognition of radar signalsdemonstrates that the network has a fast convergence speed with good performances. | Gong Xinbao Zang Xiaogang Zhou Xilang Hu Guangrui (Dept. of Electronic Eng., Shanghai Jiaotong Univ., Shanghai 200030) | 2003 | Journal of Electronics(China)2003，20，5： | 1 |
| 13 | An investigation on microwave transmissivity at frequencies of 18.7 and 36.5 GHz for diverse forest types during snow season显示文摘Forests have invariably been considered as an obstacle in retrieving land surface parameters from spaceborne passive microwave brightness temperature(T_(B))observations.For quantifying the effect of forests on microwave signals,several models have been developed.However,these models rarely reveal the dependence of microwave radiation on forest types,which can hardly meet the needs of high-accuracy retrieval of terrestrial parameters in forested regions.A ground-based microwave radiometric observation experiment was designed to investigate the dependence of microwave radiation on frequency,polarization,and forest type.Downward TB at 18.7-and 36.5-GHz for horizontal-and vertical-polarization from the forest canopy was measured at 14 sample plots in Northeast China,along with snowpack and forest structural parameters.By providing fits to experimental data,new empirical transmissivity models for three forest types were developed,as a function of woody stem volume and depending on the frequency/polarization.The proposed models give diverse asymptotic transmissivity saturation levels and the corresponding saturation point of woody stem volume for different forest types.Root-mean-square error results between T_(B) simulations and Advanced Microwave Scanning Radiometer-2 observations are approximately 3-6 K.This study provides an experimental and theoretical reference for further development of inversion models for snow parameters in forested areas. | Wang Guangrui Li Xiaofeng Chen Xiuxue Jiang Tao Zheng Xingming Wei Yanlin Wan Xiangkun Wang Jian | 2021 | International Journal of Digital Earth2021，14，10： | 1 |
| 14 | CT angiography and MRI in patients withpopliteal artery entrapment syndrome显示文摘 | Hai Z Guangrui S Yuan Z | | 0，，： | 1 |
| 15 | China ready for new prospect for tourism development显示文摘 | Zhang Guangrui | 1985 | Tourism Management1985，2，： | 1 |
| 16 | PPARG in Human Adipogenesis: Differential Contribution of Canonical Transcripts and Dominant Negative Isoforms显示文摘 | M. Aprile M. R. Ambrosio V. D’Esposito F. Beguinot P. Formisano V. Costa A. Ciccodicola Guangrui Yang | 2014 | PPAR Research2014，，： | 1 |
| 17 | CT angiography and MRI in patients with popliteal artery entrapment syndrome显示文摘 | Hai Z Guangrui S Yuan Z | 2008 | AJR Am J Roentgenol2008，191，6： | 1 |
| 18 | Technical Review on Jet Fuel Production显示文摘 | LIU Guangrui YAN Beibei CHEN Guanyi | 2013 | Renewable and Sustainable Energy Reviews2013，25，： | 1 |
| 19 | Controlling chaos by a modified straight-line stabilization method 显示文摘 | Wang Guangrui Chen Shigang | 2001 | Eur Phys J B2001，22，： | 1 |
| 20 | 20-HETE Induces Hyperglycemia through the cA MP/PKA-Ph K-GP Pathway显示文摘 | Guangrui Lai Jingjing Wu Xiaoliang Liu | 2012 | Mol Endocrinol2012，26，11： | 1 |
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