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56篇 您的检索式：作者名="Guedj"

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	题名	作者	年代	出处	被引量
1	Disease control with sunitinib in advanced intrahepatic cholangiocarcinoma resistant to gemcitabine-oxaliplatin chemotherapy显示文摘Advanced cholangiocarcinoma is associated with poor prognostic survival and has limited therapeutic options available at present. The importance of angiogenesis and expression of pro-angiogenic factors in intrahepatic forms of cholangiocarcinoma suggest that therapies targeting angiogenesis might be useful for the treatment of this disease. Here we report three cases of patients with advanced intrahepatic cholangiocarcinoma progressive after standard chemotherapy and treated with sunitinib 50 mg/d in 6-wk cycles of 4 wk on treatment followed by 2 wk off treatment(Schedule 4/2). In all three patients, sunitinib treatment was associated with a sustained disease control superior to 4 mo, patients achieving either a partial response or stable disease. A reduction in tumor size and density was observed in all cases, suggesting tumor necrosis as a result of sunitinib treatment in these patients. In addition, sunitinib was generally well tolerated and the occurrence of side effects was managed with standard medical interventions, as required. Our results suggest that sunitinib therapy maybe associated with favorable outcomes and tolerability in patients with advanced cholangiocarcinoma. Those observations contributed to launch a prospective phase Ⅱ multicenter trial investigating sunitinib in advanced intrahepatic cholangiocarcinoma(SUN-CK study; NCT01718327).	Chantal Dreyer Marie-Paule Sablin Mohamed Bouattour Cindy Neuzillet Maxime Ronot Safi Dokmak Jacques Belghiti Nathalie Guedj Valérie Paradis Eric Raymond Sandrine Faivre	2015	World Journal of Hepatology2015，7，6：	4
2	Innate Immune Tolerance and the Role of Kupffer Cells in Differential Responses to Interferon Therapy Among Patients with HCV Genotype 1 Infection显示文摘	Daryl T.-Y. Lau Amina Negash Jie Chen Nanette Crochet Mala Sinha Yuhong Zhang Jeremie Guedj Sharon Holder Takeshi Saito Stanley M. Lemon Bruce A. Luxon Alan S. Perelson Michael Gale	2012	Gastroenterology2012，，：	2
3	Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A 显示文摘	Guedj F Sebrie C Rivals I	2009	PLoS One2009，4，2：	1
4	Is it acceptable for a psychiatrist to break confidentiality to prevent spousal violence显示文摘	Guedj M Sastre MT Mullet E		0，，2：	1
5	Patients' motives for consenting or refusing to participate in a clinical trial in organ transplantation 显示文摘	Guedj M Ballester S Kamar N	2013	Clin Transplant2013，27，5：	1
6	Usefulness of 2‐[<sup>18</sup>F]‐fluoro‐2‐deoxy‐ d ‐glucose–Positron Emission Tomography/Computed Tomography for Staging and Evaluation of Treatment Response in IgG4‐Related Disease: A Retrospective Multicenter Study显示文摘	Mikael Ebbo Aurélie Grados Eric Guedj Delphine Gobert Cécile Colavolpe Mohamad Zaidan Agathe Masseau Fanny Bernard Jean‐Marie Berthelot Nathalie Morel Fran?ois Lifermann Sylvain Palat Julien Haroche Xavier Mariette Bertrand Godeau Emmanuelle Bernit Nathal	2014	Arthritis Care & Research2014，，1：	1
7	Striatal hypermetabolismin limbic encephalitis 显示文摘	Rey C Koric L Guedj E	2012	J Neurol2012，259，6：	1
8	Association of the TNFAIP3 rs5029939 variant with systemic sclerosis in the European Caucasian population显示文摘	Dieudé P Guedj M Wipff J	2010	Ann Rheum Dis2010，69，11：	1
9	Angiogenesis and extracellular matrix remodelling in bronchioloalveolar carcinomas:distinctive patterns in mucinous and non-mucinous tumours显示文摘	Guedj N Couvelard A Arcangeli G	2004	Histopathology2004，44，3：	1
10	Partially reversible cortical metabolic dysfunction in familial hemiplegic migraine with prolonged aura显示文摘	Guedj E Belenotti P Serratrice J	2010	Headache2010，50，5：	1
11	Angiogenesis and extracellular matrix remodeling in brochioloalveolar carcinomas: distinctive patterns in mucinous and non-mucinous tumors 显示文摘	Guedj N Couvelard A Arcangeli G	2004	Histopathol2004，44，3：	1
12	Utility of FDG PET/CT in the follow up of neuroblastoma which became MIBG-negative显示文摘	Colavolpe C Guedj E Cammilleri S	2008	Pediatr Blood Cancer2008，51，6：	1
13	Childhood beh(c)et'e disease:Clinical features and comparison with adult-onset disease显示文摘	Krause I Uziel Y Guedj D		0，，：	1
14	Resting metabolic connectivity in prodromal Alzheimer’s disease. A European Alzheimer Disease Consortium (EADC) project显示文摘	Silvia Morbelli Alex Drzezga Robert Perneczky Giovanni B. Frisoni Anna Caroli Bart N.M. van Berckel Rik Ossenkoppele Eric Guedj Mira Didic Andrea Brugnolo Gianmario Sambuceti Marco Pagani Eric Salmon Flavio Nobili	2012	Neurobiology of Aging2012，，：	1
15	Angiogenesis and extracellular matrix remodelling in bronchioloalveolar carcino- mas: distinctive patterns inmucinous and non-mutinous tumours显示文摘	Guedj N Couvelard A Areangeli G	2004	Histopathology2004，44，3：	1
16	Association of the CD226 Ser(307) variant with systemic sclerosis: evidence of a contribution of costimulation pathways in systemic sclerosis pathogenesis 显示文摘	Dieud6 P Guedj M Truchetet ME	2011	Arthritis Rheum2011，63，4：	1
17	Decreased basal fMRI functional connectivity in epileptogenic networks and contralateral compensatory mechanisms显示文摘	Bettus G Guedj E Joyeux F	2009	Hum Brain Mapp2009，30，5：	1
18	A refined molecular taxonomy of breast cancer显示文摘	Guedj M Marisa L de Reynies A	2012	Oncogene2012，31，9：	1
19	Association of a KCNA5 gene polymorphism with systemic sclerosis-associated pulmonary arterial hypertension in the European Caucasian population 显示文摘	Wipff J Dieude P Guedj M	2010	Arthritis Rheum2010，62，10：	1
20	A refined molecular taxonomy of breast cancer显示文摘	Guedj M Marisa L de Reynies A	2012	Oncogene2012，31，9：	1

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