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| 1 | A review on completing arsenic biogeochemical cycle: Microbial volatilization of arsines in environment显示文摘Arsenic(As) is ubiquitous in the environment in the carcinogenic inorganic forms, posing risks to human health in many parts of the world. Many microorganisms have evolved a series of mechanisms to cope with inorganic arsenic in their growth media such as transforming As compounds into volatile derivatives. Bio-volatilization of As has been suggested to play an important role in global As biogeochemical cycling, and can also be explored as a potential method for arsenic bioremediation. This review aims to provide an overview of the quality and quantity of As volatilization by fungi, bacteria, microalga and protozoans. Arsenic bio-volatilization is influenced by both biotic and abiotic factors that can be manipulated/elucidated for the purpose of As bioremediation. Since As biovolatilization is a resurgent topic for both biogeochemistry and environmental health, our review serves as a concept paper for future research directions. | Peipei Wang Guoxin Sun Yan Jia Andrew A Meharg Yongguan Zhu | 2014 | Journal of Environmental Sciences2014，26，2： | 22 |
| 2 | Black phosphorus as a new lubricant显示文摘In recent years, a new 2D-layered material—black phosphorus(BP)—has been a rising star after the era of graphene owing to its high charge carrier mobility, tunable direct bandgap and unique in-plane anisotropic structure. With the development of the synthesis and modification methods of BP, its extensive applications, e.g., transistors, batteries and optoelectronics have emerged. In order to explore its full potential, research into the tribological properties of BP 2D-layered materials such as lubrication additives and fillers in self-lubricating composite materials would be not only of high scientific value but also of practical significance. In this work, recent advances on the friction and lubrication properties of BP nanosheets made by our group, including the micro-friction properties, the lubrication properties of BP nanosheets as water-based and oil-based lubrication additives, and the friction and wear of BP/PVDF composites will be presented. Finally, the future challenges and opportunities in the use of BP materials as lubricants will be discussed. | Wei WANG Guoxin XIE Jianbin LUO | 2018 | Friction2018，6，1： | 23 |
| 3 | Rolling texture and its effect on tensile property of a near-α titanium alloy Ti60 plate显示文摘Rolling texture and its effect on tensile properties of Ti60 alloy plates were investigated in the present study. The plates were β-rolled at 1070℃ and(α+β)-rolled at 980℃, using uni-directionally rolling(UDR) and cross-directionally rolling(CDR) processes, respectively.β-rolled plates exhibited weak textures, which were attributed to the dispersive orientations of secondary α during the β→α phase transformation. Strong deformation textures formed in(α+β)-rolled plates as a result of slipping mechanisms: the strong T-type texture in UDR plate was related to {10 1 0}[11 2 0] slipping, while the B-type texture in CDR plate was relevant with {0001}[11 2 0] slip. Strong T-type textures led to anisotropic tensile properties. B-type textures would decrease such an anisotropy. The(α+β)-CDR process was found to be a candidate process for reducing anisotropy of Ti60 alloy plates. | Wenyuan Li Zhiyong Chen Jianrong Liu Shaoxiang Zhu Guoxin Sui Qingjiang Wang | 2019 | Journal of Materials Science & Technology2019，35，5： | 11 |
| 4 | Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration显示文摘The host immune response effecting on biomaterials is critical to determine implant fates and bone regeneration property.Bone marrow stem cells(BMSCs)derived exosomes(Exos)contain multiple biosignal molecules and have been demonstrated to exhibit immunomodulatory functions.Herein,we develop a BMSC-derived Exos-functionalized implant to accelerate bone integration by immunoregulation.BMSC-derived Exos were reversibly incorporated on tannic acid(TA)modified sulfonated polyetheretherketone(SPEEK)via the strong interaction of TA with biomacromolecules.The slowly released Exos from SPEEK can be phagocytosed by co-cultured cells,which could efficiently improve the biocompatibilities of SPEEK.In vitro results showed the Exos loaded SPEEK promoted macrophage M2 polarization via the NF-κB pathway to enhance BMSCs osteogenic differentiation.Further in vivo rat air-pouch model and rat femoral drilling model assessment of Exos loaded SPEEK revealed efficient macrophage M2 polarization,desirable new bone formation,and satisfactory osseointegration.Thus,BMSC-derived Exos-functionalized implant exerted osteoimmunomodulation effect to promote osteogenesis. | Lei Fan Pengfei Guan Cairong Xiao Huiquan Wen Qiyou Wang Can Liu Yian Luo Limin Ma Guoxin Tan Peng Yu Lei Zhou Chengyun Ning | 2021 | Bioactive Materials2021，6，9： | 11 |
| 5 | Effect of microbial mediated iron plaque reduction on arsenic mobility in paddy soil显示文摘The potential of microbial mediated iron plaque reduction, and associated arsenic (As) mobility were examined by iron reducing bacteria enriched from As contaminated paddy soil. To our knowledge, this is the first time to report the impact of microbial iron plaque reduction on As mobility. Iron reduction occurred during the inoculation of iron reducing enrichment culture in the treatments with iron plaque and ferrihydrite as the electron acceptors, respectively. The Fe(II) concentration with the treatment of anthraquinone-2, 6-disulfonic acid (AQDS) and iron reducing bacteria increased much faster than the control. Arsenic released from iron plaque with the iron reduction, and a significant correlation between Fe(II) and total As in culture was observed. However, compared with control, the increasing rate of As was inhibited by iron reducing bacteria especially in the presence of AQDS. In addition, the concentrations of As(III) and As(V) in abiotic treatments were higher than those in the biotic treatments at day 30. These results indicated that both microbial and chemical reductions of iron plaque caused As release from iron plaque to aqueous phase, however, microbial iron reduction induced the formation of more crystalline iron minerals, leading to As sequestration. In addition, the presence of AQDS in solution can accelerate the iron reduction, the As release from iron plaque and subsequently the As retention in the crystalline iron mineral. Thus, our results suggested that it is possible to remediate As contaminated soils by utilizing iron reducing bacteria and AQDS. | WANG Xinjun CHEN Xueping YANG Jing WANG Zhaosu SUN Guoxin | 2009 | Journal of Environmental Sciences2009，21，11： | 11 |
| 6 | Growth and characterization of 0.8-μm gate length AlGaN/GaN HEMTs on sapphire substrates显示文摘AlGaN/GaN high electron mobility transistor (HEMT) structures were grown on 2 inch sapphire substrates by MOCVD, and 0.8-μm gate length devices were fabricated and measured. It is shown by resistance mapping that the HEMT structures have an average sheet resistance of approximately 380 ?/sq with a uniformity of more than 96%. The 1-mm gate width devices using the materials yielded a pulsed drain current of 784 mA/mm at Vgs=0.5 V and Vds=7 V with an extrinsic transconductance of 200 mS/mm. A 20-GHz unity current gain cutoff frequency (?T ) and a 28-GHz maximum oscillation frequency (?max) were obtained. The device with a 0.6-mm gate width yielded a total output power of 2.0 W/mm (power density of 3.33 W/mm) with 41% power added efficiency (PAE) at 4 GHz. | WANG Xiaoliang WANG Cuimei HU Guoxin WANG Junxi RAN Junxue FANG Cebao LI Jianping ZENG Yiping LI Jinmin LIU Xinyu LIU Jian QIAN He | 2005 | Science in China(Series F)2005，48，6： | 7 |
| 7 | Silencing RhoA inhibits migration and invasion through Wnt/β-catenin pathway and growth through cell cycle regulation in human tongue cancer显示文摘地岬相当或相同的事物基因家庭成员 A (RhoA ) 作为肿瘤的一个批评管理者被识别了好攻击的行为。在 thisstudy,我们在位于有鳞的细胞 carcinomaof 舌头(TSCC ) 的生长,移植,和侵略下面的机制估计了 RhoA 的角色。TSCC 房间线 SCC-4 和 CAL27 击倒的稳定的 RhoA 用 Lentiviral transfection 被完成。房间移植,侵略,和房间增长上的 RhoA 弄空的 Theeffects 是坚定的。TSCC 房间线上的可能的位于决定 Galectin-3 (Gal-3 ) 的表示下面 mechanismof RhoA 弄空被也评估,在 vivo 的 -catenin, andmatrix metalloproteinase-9 (MMP-9 ) 。同时, TSCC 生长的内在的机制被 cyclin D1/2 的分析学习, p21 CIP1/WAF1 , 和 p27 Kip1 蛋白质层次。Immunohistochemical 评价被执行进一步证明 Gal-3 和 -catenin expression.We 的改变发现了那,在与在舌头的人的 TSCC 房间注射的老鼠, RhoA 层次与在正常纸巾的那些相比在主要肿瘤和 metastasizedlymph 节点是更高的。RhoA 的 Silencing 显著地减少了肿瘤生长, Gal-3 的 decreasedthe 层次, -catenin, MMP-9,和 cyclin D1/2,并且增加了 p21 CIP1/WAF1 和 p27 Kip1 。在 vitro, RhoA 击倒也导致了房间移植,侵略,和增长的抑制。我们的数据建议 RhoA 由通过分别地通过房间周期规定表明小径 andcell 增长的 Wnt/-catenin 调整房间移植和侵略在 TSCC 前进起 asignificant 作用。RhoA 可能是 TSCC 的一个新奇治疗学的目标。 | Guoxin Yan Ronghai Zou Zhenggang Chen Bing Fan Zhaoyan Wang Ying Wang Xiaonan Yin Dong Zhang Lei Tong Fang Yang Weina Jiang Wensheng Fu Jiwei Zheng Martin O. Bergo Martin Dalin Jiawei Zheng Shulan Chen Jianhua Zhou | 2014 | Acta Biochimica et Biophysica Sinica2014，46，8： | 7 |
| 8 | Photodegradation of 2-(2-hydroxy-5-methylphenyl) benzotriazole(UV-P) in coastal seawaters: Important role of DOM显示文摘Benzotriazole UV stabilizers (BT-UVs) have attracted concems due to their ubiquitous occurrence in the aquatic environment,and their bioaccumulative and toxic properties.However,little is known about their aquatic environmental degradation behavior.In this study,photodegradation of a representative of BT-UVs,2-(2-hydroxy-5-methylphenyl) benzotriazole (UV-P),was investigated under simulated sunlight irradiation.Results show that UV-P photodegrades slower under neutral conditions (neutral form) than under acidic or alkaline conditions (cationic and anionic forms).Indirect photodegradation is a dominant elimination pathway of UV-P in coastal seawaters.Dissolved organic matter (DOM) from seawaters accelerate the photodegradation rates mainly through excited triplet DOM (3DOM*),and the roles of singlet oxygen and hydroxyl radical are negligible in the matrixes.DOM from seawaters impacted by mariculture exhibits higher steady-state concentration of 3DOM*([3DOM*]) relative to those from pristine seawaters,leading to higher photosensitizing effects on the photodegradation.Halide ions inhibit the DOM-sensitized photodegradation of UV-P by decreasing [3DOM*].Photodegradation half-lives of UV-P are estimated to range from 24.38 to 49.66 hr in field water bodies of the Yellow River estuary.These results are of importance for assessing environmental fate and risk UV-P in coastal water bodies. | Xi Chen Jieqiong Wang Jingwen Chen Chengzhi Zhou Feifei Cui Guoxin Sun | 2019 | Journal of Environmental Sciences2019，31，11： | 6 |
| 9 | Characterization of arsenate transformation and identification of arsenate reductase in a green alga Chlamydomonas reinhardtii显示文摘Arsenic (As) is a pervasive and ubiquitous environmental toxin that has created catastrophic human health problems world-wide. Chlamydomonas reinhardtii is a unicellular green alga, which exists ubiquitously in freshwater aquatic systems. Arsenic metabolism processes of this alga through arsenate reduction and sequent store and efflux were investigated. When supplied with 10 μmol/L arsenate, arsenic speciation analysis showed that arsenite concentration increased from 5.7 to 15.7 mg/kg dry weight during a 7-day period, accounting for 18%–24% of the total As in alga. When treated with different levels of arsenate (10, 20, 30, 40, 50 μmol/L) for 7 days, the arsenite concentration increased with increasing external arsenate concentrations, the proportion of arsenite was up to 23%–28% of the total As in alga. In efflux experiments, both arsenate and arsenite could be found in the efflux solutions. Additionally, the efflux of arsenate was more than that of arsenite. Furthermore, two arsenate reductase genes of C. reinhardtii (CrACR2s) were cloned and expressed in Escherichia coli strain WC3110 (?arsC) for the first time. The abilities of both CrACR2s genes to complement the arsenate- sensitive strain were examined. CrACR2.1 restored arsenate resistance at 0.8 mmol/L. However, CrACR2.2 showed much less ability to complement. The gene products were demonstrated to reduce arsenate to arsenite in vivo. In agreement with the complementation results, CrACR2.1 showed higher reduction ability than CrACR2.2, when treated with 0.4 mmol/L arsenate for 16 hr incubation. | Xixiang Yin Lihong Wang Guilan Duan Guoxin Sun | 2011 | Journal of Environmental Sciences2011，23，7： | 6 |
| 10 | Properties of Xanthoceras sorbifolia Husk Fibers With Chemical Treatment for Applications in Polymer Composites显示文摘Surface science of natural fibers plays an important role in polymer/natural fiber composites. The Xanthoceras sorbifolia husk fibers were selected and chemically treated by sodium hydroxide(Na OH) solution,coupling agents,their combination,and the mixtures of acetic acid with hydrogen peroxide,respectively. 3-aminopropyltriethoxysilane(KH550),γ-methacryloxypropyltrimethoxylsilane(KH570) and organic titanate(JN-9A) were used as coupling agents in this work. Cellulose content was found to be increased after alkalization due to the removal of the non-cellulose substances,which was evidenced by attenuated total reflectance-Fourier transform infrared(ATR e FTIR) spectroscopy spectrum analysis and thermogravimetric analysis(TGA) measurements. The highest cellulose content was obtained in the bleached fibers. TGA analysis revealed an improvement in thermal stability of the treated fibers,especially for alkali-KH570 treated fibers. The tensile strength of the alkali-KH570 treated fiber and the alkali-bleached fiber were higher than that of other fibers due to high cellulose content and high crystallinity. | Hongyu Wang Xudan Yao Guoxin Sui Liming Yin Lihua Wang | 2015 | Journal of Materials Science & Technology2015，31，2： | 6 |
| 11 | Hierarchical peony-like FeCo-NC with conductive network and highly active sites as efficient electrocatalyst for rechargeable Zn-air battery显示文摘Carbon materials featuring hierarchical pores and atomically dispersed metal sites are promising catalysts for energy storage and conversion applications.Herein,we developed a facile strategy to construct functional carbon materials with a fluffy peony-like structure and dense binary FeCo-Nx active sites(termed as f-FeCo-CNT).By regulating the metal content in precursors,a three-dimensional(3D)interconnected conductive carbon nanotubes network was in-situ formed throughout the atomically dispersed FeCo-NC matrix during pyrolysis.Taking advantage of rich pore hierarchy and co-existence of highly active FeCo-Nx sites and beneficial FeCo alloy nanoparticles,the f-FeCo-CNT material exhibited excellent bifunctional performance towards oxygen reduction reaction/oxygen evolution reactions(ORR/OER)with respect to the atomically dispersed FeCo-NC(SA-f-FeCo-NC)and commercial Pt/C+Ru02 mixture,surpassing the SA-f-FeCo-NC with a 20 mV higher ORR half-wave potential and a 100 mV lower OER overpotential(at 10.0 mA/cm^2).Remarkably,the f-FeCo-CNT-assembled Zn-air battery(ZAB)possessed a maximum specific power of 195.8 mW/cm^2,excellent rate capability,and very good cycling stability at large current density of 20.0 mA/cm^2.This work provides a facile and feasible synthetic strategy of constructing low-cost cathode materials with excellent comprehensive ZAB performance. | Yiyan Wang Anuj Kumar Mang Ma Yin Jia Yu Wang Ying Zhang Guoxin Zhang Xiaoming Sun Zifeng Yan | 2020 | Nano Research2020，13，4： | 5 |
| 12 | β-Glucosidase treatment and infestation by the rice brown planthopper Nilaparvata lugens elicit similar signaling pathways in rice plants显示文摘β-Glucosidase has been reported to induce the production of herbivore-induced plant volatiles. How-ever, how it works remains unclear. Here, we investigated the levels of salicylic acid (SA), jasmonic acid (JA), ethylene, and H2O2, all of which are known signaling molecules that play important roles in in-duced plant defense in rice plants treated with β-glucosidase, and compared these to levels in plants infested by the rice brown planthopper Nilaparvata lugens (Stl). Results showed that wounding and treatment by β-glucosidase increased the levels of SA, ethylene, and H2O2, but not JA, in all plants compared to control plants. The signaling pathways activated by β-glucosidase treatment are similar to those activated by an infestation by N. lugens, although the magnitude and timing of the signals elicited by the two treatments are different. This may explain why both treatments have similar volatile profiles and are equally attractive to the parasitoid Anagrus nilaparvatae Pang et Wang. | WANG Xia ZHOU GuoXin XIANG CaiYu DU MengHao CHENG JiaAn LIU ShuSheng LOU YongGen | 2008 | Chinese Science Bulletin2008，53，1： | 5 |
| 13 | Salicylic acid and ethylene signaling pathways are involved in production of rice trypsin proteinase inhibitors induced by the leaf folder Cnaphalocrocis medinalis(Guenée)显示文摘The roles of signaling pathways in the production of trypsin proteinase inhibitors(TrypPIs)in rice infested by the leaf folder(LF) Cnaphalocrocis medinalis were studied.Infestation by LF increased TrypPI levels in the leaves of rice plants at the tillering,booting and flowering stages but decreased TrypPI levels at the ripening stage;TrypPI levels in rice stems did not increase at any developmental stage.Infestation by LF at the tillering stage systemically increased TrypPI levels in leaves but not in stems;it also enhanced salicylic acid(SA)levels in leaves and stems,and the ethylene level released from plants.However,LF infestation did not increase JA concentrations.Exogenous application of SA or ethylene enhanced TrypPI levels in the leaves and stems of plants at the tillering stage,whereas treatment with both SA and ethylene induced lower levels of TrypPIs than treatment with SA or ethylene alone,suggesting an antagonistic effect of SA and ethylene on TrypPIs induction.The results suggest that both SA and ethylene signaling pathways are involved in the production of TrypPIs in rice induced by LF;moreover,the antagonistic effect of SA and ethylene may explain the changes in TrypPI levels seen at different plant developmental stages and in different organs. | WANG Xia HU LiuCheng ZHOU GuoXin CHENG JiaAn LOU YongGen | 2011 | Chinese Science Bulletin2011，56，22： | 5 |
| 14 | SNHG1 functions as an oncogenic lncRNA and promotes osteosarcoma progression by up-regulating S100A6 viamiR-493-5p显示文摘The mechanism behind the aberrant expression of S100A6 in osteosarcoma is seldom reported so far.This study sought to explore the regulatory axis targeting S100A6 involved in osteosarcoma progression.Clinical samples collected from osteosarcoma patients were used to detect the expressions of SNHG1,miR-493-5p,and S100A6 by western bolt analysis and reverse transcription-quantitative polymerase chain reaction(RT-qPCR).The effects of S100A6 on proliferation and osteogenic differentiation were investigated by the CCK-8 assay,colony formation assay,Ethynyl deoxyuridine staining,matrix mineralization assay,and alkaline phosphatase assay.The potential of lncRNAs/miRNAs targeting S100A6 was identified by the bioinformatics approach,and the results were verified by the dual luciferase assay and RNA immunoprecipitation assay.Both in vitro and in vivo rescue experiments were performed to investigate the regulatory relationship between the identified lncRNAs and S100A6.The results showed that S100A6 is highly expressed in osteosarcoma.S100A6 overexpression not only increases the proliferation but also reduces the osteogenic differentiation of osteosarcoma cells,while S1006A silence exerts the opposite effects.Then,SNHG1 is identified to directly interact with miR-493-5p to attenuate miR-493-5p binding to the 3′-untranslated region of S100A6.Notably,S100A6 silence partially rescues the effect of SNHG1 overexpression on proliferation and osteogenic differentiation of osteosarcoma cells.Furthermore,the suppressive role of SNHG1 silence in the growth of osteosarcoma xenograft tumors is countered by S100A6 overexpression.Collectively,this study reveals that S100A6 plays an important role in osteosarcoma progression,and SNHG1 promotes S100A6 expression by competitively sponging miR-493-5p. | Qi Liu Jiaying Luo Huan Wang Lei Zhang Guoxin Jin | 2022 | Acta Biochimica et Biophysica Sinica2022，54，1： | 5 |
| 15 | A multi-axis robot-based bioprinting system supporting natural cell function preservation and cardiac tissue fabrication显示文摘Despite the recent advances in artificial tissue and organ engineering,how to generate large size viable and functional complex organs still remains as a grand challenge for regenerative medicine.Three-dimensional bioprinting has demonstrated its advantages as one of the major methods in fabricating simple tissues,yet it still faces difficulties to generate vasculatures and preserve cell functions in complex organ production.Here,we overcome the limitations of conventional bioprinting systems by converting a six degree-of-freedom robotic arm into a bioprinter,therefore enables cell printing on 3D complex-shaped vascular scaffolds from all directions.We also developed an oil bath-based cell printing method to better preserve cell natural functions after printing.Together with a self-designed bioreactor and a repeated print-and-culture strategy,our bioprinting system is capable to generate vascularized,contractible,and long-term survived cardiac tissues.Such bioprinting strategy mimics the in vivo organ development process and presents a promising solution for in vitro fabrication of complex organs. | Zeyu Zhang Chenming Wu Chengkai Dai Qingqing Shi Guoxin Fang Dongfang Xie Xiangjie Zhao Yong-Jin Liu Charlie CLWang Xiu-Jie Wang | 2022 | Bioactive Materials2022，7，12： | 4 |
| 16 | Steganalytic method based on short and repeated sequence distance statistics显示文摘According to the distribution characteristics of short and repeated sequence (SRS),a steganalytic method based on the correlation of image bit planes is proposed. Firstly,we provide the conception of SRS distance statistics and deduce its statis-tical distribution. Because the SRS distance statistics can effectively reflect the correlation of the sequence,SRS has statistical features when the image bit plane sequence equals the image width. Using this characteristic,the steganalytic method is fulfilled by the distinct test of Poisson distribution. Experimental results show a good performance for detecting LSB matching steganographic method in still images. By the way,the proposed method is not designed for specific steg-anographic algorithms and has good generality. | WANG GuoXin PING XiJian XU ManKun ZHANG Tao BAO XiRui | 2008 | Science in China(Series F)2008，51，10： | 4 |
| 17 | Ordered mesoporous NiFe_2O_4 with ultrathin framework for low-ppb toluene sensing显示文摘Highly sensitive and selective detection against specific target gases,especially at low-ppb(part per billion)level,remain a great number of challenges in gas sensor applications.In this paper,we first present an ordered mesoporous NiFe_2O_4 for highly sensitive and selective detection against low-ppb toluene.A series of mesoporous NiFe_2O_4 materials were synthesized by templating from mesoporous silica KIT-6 and its framework thickness was reduced from 8.5 to 5 nm by varying the pore size of KIT-6 from 9.4 to 5.6 nm,accompanied with the increase of the specific surface area from 134 to 216 m^2g^(-1).The ordered mesoporous NiFe_2O_4 with both ultrathin framework of 5 nm and large specific surface area of up to 216 m^2g^(-1)exhibits a highest response(R_(gas)/R_(air)-1=77.3)toward 1,000 ppb toluene at 230℃ and is nearly 7.3 and 76.7 times higher than those for the NiFe_2O_4 replica with thick framework and its bulk counterpart respectively,which also possesses a quite low limit of detection(<2 ppb),and good selectivity. | Xiaoyong Lai Kun Cao Guoxin Shen Ping Xue Dan Wang Fang Hu Jianli Zhang Qingfeng Yang Xiaozhong Wang | 2018 | Science Bulletin2018，63，3： | 3 |
| 18 | A hybrid genipin-crosslinked dual-sensitive hydrogel/nanostructured lipid carrier ocular drug delivery platform显示文摘The objective of this study was to develop a novel hybrid genipin-crosslinked dual-sensitive hydrogel/nanostructured lipid carrier(NLC) drug delivery platform. An ophthalmic antiinflammatory drug, baicalin(BN) was chosen as the model drug. BN –NLC was prepared using melt-emulsification combined with ultra-sonication technique. Additionally, a dual pH-and thermo-sensitive hydrogel composed of carboxymethyl chitosan(CMCS) and poloxamer 407(F127) was fabricated by a cross-linking reaction with a nontoxic crosslinker genipin(GP). GP-CMCS/F127 hydrogel was characterized by FTIR, NMR, XRD and SEM. The swelling studies showed GP-CMCS/F127 hydrogel was both pH-and thermo-sensitive. The results of in vitro release suggested BN –NLC gel can prolong the release of baicalin comparing with BN eye drops and BN –NLC. Ex vivo cornea permeation study was evaluated using Franz diffusion cells. The apparent permeability coefficient(Papp) of BN –NLC gel was much higher(4.46-fold) than that of BN eye drops. Through the determination of corneal hydration levels, BN –NLC gel was confirmed that had no significant irritation to cornea. Ex vivo precorneal retention experiments were carried out by a flow-through approach. The results indicated that the NLC-based hydrogel can prolong precorneal residence time. In conclusion, the hybrid NLCbased hydrogel has a promising potential for application in ocular drug delivery. | Yibin Yu Ruoxi Feng Jinyu Li Yuanyuan Wang Yiming Song Guoxin Tan Dandan Liu Wei Liu Xinggang Yang Hao Pan Sanming Li | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，4： | 3 |
| 19 | Low temperature catalytic oxidation of NO over different-shaped CeO2显示文摘To investigate the effect of CeO_2 nanomaterial morphology on its performance for NO catalytic oxidation.Three kinds of CeO_2 nanomaterials including CeO_2 nanorods,nanospheres and nanoparticles were prepared by hydrothermal method and used for catalytic oxidation of NO at low temperature. The experimental results show that CeO_2 nanorods are of the best catalytic performance. Characterization techniques including TEM, XRD, H_2-TPR, NO-TPD and XPS were used to determine the relationship between the morphology of CeO_2 nanomaterial and its catalytic performance. TEM images show that CeO_2 nanorods predominantly exposed(110) and(10 0) planes, while CeO_2 nanospheres and CeO_2 nanoparticles predominantly exposed(111) plane. The excellent catalytic performance of CeO_2 nanorods could be ascribed to the low crystallinity, high reducibility, strong NO adsorption ability and the presence of more surface chemisorbed oxygen. | Wenhuan Wang Ruitang Guo Weiguo Pan Guoxin Hu | 2018 | Journal of Rare Earths2018，36，6： | 3 |
| 20 | Dynamic corner frequency in source spectral model for stochastic synthesis of ground motion显示文摘The static corner frequency and dynamic corner frequency in stochastic synthesis of ground motion from finite-fault modeling are introduced, and conceptual disadvantages of the two are discussed in this paper. Furthermore, the non-uniform radiation of seismic wave on the fault plane, as well as the trend of the larger rupture area, the lower corner frequency, can be described by the source spectral model developed by the authors. A new dynamic corner frequency can be developed directly from the model. The dependence of ground motion on the size of subfault can be eliminated if this source spectral model is adopted in the synthesis. Finally, the approach presented is validated from the comparison between the synthesized and observed ground motions at six rock stations during the Northridge earthquake in 1994. | Xiaodan Sun Xiaxin Tao Guoxin Wang Taojun Liu | 2009 | Earthquake Science2009，22，3： | 3 |
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