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| 1 | Post-endoscopic retrograde cholangiopancreatography pancreatitis: Risk factors and predictors of severity显示文摘AIM To detect risk factors for post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis(PEP) and investigate the predictors of its severity.METHODS This is a prospective cohort study of all patients who underwent ERCP.Pre-ERCP data,intraoperative data,and post-ERCP data were collected.RESULTS The study population consisted of 996 patients.Their mean age at presentation was 58.42(± 14.72) years,and there were 454 male and 442 female patients.Overall,PEP occurred in 102(10.2%) patients of the study population; eighty(78.4%) cases were of mild to moderate degree,while severe pancreatitis occurred in 22(21.6%) patients.No hospital mortality was reported for any of PEP patients during the study duration.Age less than 35 years(P = 0.001,OR = 0.035),narrower common bile duct(CBD) diameter(P = 0.0001) and increased number of pancreatic cannulations(P = 0.0001) were independent risk factors for the occurrence of PEP.CONCLUSION PEP is the most frequent and devastating complication after ERCP.Age less than 35 years,narrower median CBD diameter and increased number of pancreaticcannulations are independent risk factors for the occurrence of PEP.Patients with these risk factors are candidates for prophylactic and preventive measures against PEP. | Ayman El Nakeeb Ehab El Hanafy Tarek Salah Ehab Atef Hosam Hamed Ahmad M Sultan Emad Hamdy Mohamed Said Ahmed A El Geidie Tharwat Kandil Mohamed El Shobari Gamal El Ebidy | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，19： | 10 |
| 2 | Immunity Genes and Susceptibility to Otitis Media:A Comprehensive Review显示文摘Otitis media(OM) is a middle ear infection associated with inflammation and pain.This disease frequently afflicts humans and is the major cause of hearing loss worldwide.OM continues to be one of the most challenging diseases in the medical field due to its diverse host targets and wide range of clinical manifestations.Substantial morbidity associated with OM is further exacerbated by high frequency of recurrent infections leading to chronic suppurative otitis media(CSOM).Children have greater susceptibility to,and thus,suffer most frequently from OM,which can cause significant deterioration in quality of life.Genetic factors have been demonstrated,in large part by twin and family studies,to be key determinants of OM susceptibility.In this review,we summarize the current knowledge on immunity genes and selected variants that have been associated with predisposition to OM.In particular,polymorphisms in innate immunity and cytokine genes have been strongly linked with the risk of developing OM.Future studies employing state-of-the-art technologies,including next-generation sequencing(NGS),will aid in the identification of novel genes associated with susceptibility to OM.This,in turn,will open up avenues for identifying high-risk individuals and designing novel therapeutic strategies based on precise targeting of these genes. | Rahul Mittal Giannina Robalino Robert Gerring Brandon Chan Denise Yan M'hamed Grati Xue-Zhong Liu | 2014 | Journal of Genetics and Genomics2014，41，11： | 5 |
| 3 | SMILE intraoperative complications: incidence and management显示文摘AIM: To report the intraoperative complications associated with small incision lenticule extraction(SMILE) and their management. METHODS: This was a retrospective consecutive interventional clinical study, carried out on patients with myopia and myopic astigmatism, who underwent SMILE procedure. Type of intraoperative complications and their management were recorded. RESULTS: Our study comprised 282 eyes of 141 patients who were enrolled for SMILE surgeries. The intraoperative complications included lost vacuum(18 eyes, 6.38%), treatment decentration(6 eyes, 2.12%), wound bleeding(21 eyes, 7.45%), incomplete bubble separation(black islands)(3 eyes, 1.06%), the epithelial defects(15 eyes, 5.32%). Incision tear(27 eyes, 9.57%), lenticule adherence to the cap(6 eyes, 2.12%), and cap perforation occurred in 2 eyes(0.7%). CONCLUSION: Although SMILE is a promising technique for the correction of myopia and myopic astigmatism with predictable, efficient, safe refractive and visual outcomes, complications can occur. However, most of them are related to inexperience and are included in the learning curve of the technique. More studies with a bigger number of eyes are required to efficiently evaluate the intraoperative complications and standardize their management strategies. | Abdelmonem M Hamed Mohamed Amin Heikal Tarek T.Soliman Ahmed Daifalla Khaled E Said-Ahmed | 2019 | International Journal of Ophthalmology(English edition)2019，12，2： | 4 |
| 4 | Biliary leakage following pancreaticoduodenectomy:Prevalence,risk factors and management显示文摘Background: Few studies investigated biliary leakage after pancreaticoduodenectomy(PD) especially when compared to postoperative pancreatic fistula(POPF). This study was to determine the incidence of biliary leakage after PD, predisposing factors of biliary leakage, and its management. Methods: We retrospectively studied all patients who underwent PD from January 2008 to December 2017 at Gastrointestinal Surgery Center, Mansoura University, Egypt. According to occurrence of postoperative biliary leakage, patients were divided into two groups. Group(1) included patients who developed biliary leakage and group(2) included patients without identified biliary leakage. The preoperative data, operative details, and postoperative morbidity and mortality were analyzed. Results: The study included 555 patients. Forty-four patients(7.9%) developed biliary leakage. Ten patients(1.8%) had concomitant POPF. Multivariate analysis identified obesity and time needed for hepaticojejunostomy reconstruction as independent risk factors of biliary leakage, and no history of preoperative endoscopic retrograde cholangiopancreatiography(ERCP) as protective factor. Biliary leakage from hepaticojejunostomy after PD leads to a significant increase in development of delayed gastric emptying, and wound infection. The median hospital stay and time to resume oral intake were significantly greater in the biliary leakage group. Non-surgical management was needed in 40 patients(90.9%). Only 4 patients(9.1%) required re-exploration due to biliary peritonitis and associated POPF. The mortality rate in the biliary leakage group was significantly higher than that of the non-biliary leakage group(6.8% vs 3.9%, P = 0.05). Conclusions: Obesity and time needed for hepaticojejunostomy reconstruction are independent risk factors of biliary leakage, and no history of preoperative ERCP is protective factor. Biliary leakage increases the risk of morbidity and mortality especially if concomitant with POPF. However, biliary leakage can be conservatively managed in majority of cases. | Ayman El Nakeeb Mohamed El Sorogy Hosam Hamed Rami Said Mohamad Elrefai Helmy Ezzat Waleed Askar Ahmed M Elsabbagh | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 4 |
| 5 | A chemical method to graft carbon nanotubes onto a carbon fiber显示文摘 | Abdelghani Laachachi Alexandre Vivet Gérard Nouet Bessem Ben Doudou Christophe Poilane Jun Chen Jin Bo bai M’Hamed Ayachi | 2007 | Materials Letters2007，，3： | 3 |
| 6 | Meniere’s disease显示文摘 | Hamed Sajjadi Michael M Paparella | 2008 | The Lancet2008，，9636： | 3 |
| 7 | INTESTINAL CYTOSKELETON DEGRADATION PRECEDES TIGHT JUNCTION LOSS FOLLOWING HEMORRHAGIC SHOCK显示文摘 | Geertje Thuijls Jacco-Juri de Haan Joep P. M. Derikx Isabelle Daissormont M’hamed Hadfoune Erik Heineman Wim A. Buurman | 2009 | SHOCK2009，，2： | 2 |
| 8 | Melatonin and/or rowatinex attenuate streptozotocin-induced diabetic renal injury in rats显示文摘The study aimed to explore the prophylactic effect of melatonin, rowatinex; a naturally occurring renal drug, and its combination on diabetic nephropathy in type 2 diabetic rats. Diabetes was induced by intraperitoneal injection of a single dose of streptozotocin(50 mg/g body weight). Three days before diabetes induction, rats were daily treated with melatonin, rowatinex and their combination continuously for 8 weeks. Evaluation was done through measuring blood urea nitrogen(BUN), serum uric acid, serum creatinine, urine creatinine, creatinine clearance, nitric oxide(NO), malondialdehyde(MDA), superoxide dismutase(SOD), glutathione(GSH), total antioxidant capacity(TAC),kidney injury molecule-1(KIM-1), heat shock protein-70(HSP-70), caspase-3, transforming growth factor β1(TGFβ1), DNA degradation by the comet assay and total protein contents. Histopathologic study was also done for the kidney and the pancreas. Drastic changes in all measured parameters of the diabetic rats were observed. Treatment with melatonin and rowatinex showed amelioration to variable degrees. In conclusion, melatonin showed the most potent effect on protecting rats from deleterious action of diabetic nephropathy followed by its combination with rowatinex. | Tarek K Motawi Samia A Ahmed Manal A Hamed Shohda A El-Maraghy Wessam M Aziz | 2019 | The Journal of Biomedical Research2019，33，2： | 2 |
| 9 | 显示文摘 | Hamed A M El-Sharkawy I I | 2001 | Rene wable Energy2001，22，4： | 1 |
| 10 | Modeling Travelers' Postwork Activity Involvement: Toward a New Methodology显示文摘 | HAMED M M MANNERING F L | 1993 | Transportation Science1993，27，4： | 1 |
| 11 | Condition monitoring and fault detection of wind turbines and related,algorithms:A review显示文摘 | HAMEED Z HONG Y S CHOY M | 2009 | Renewable and Sustainable Energy Reviews2009，，13： | 1 |
| 12 | Bamboo: An overlooked biomass resources 显示文摘 | SCURLOCK J M O DAYTON D C HAMES B | 2000 | Biomass and Bioenergy2000，19，4： | 1 |
| 13 | Theoretical and experimental study on the transient adsorption characteristics of a vertical packed porous bed显示文摘 | Hamed Ahmed M | 2002 | Renewable Energy2002，27，： | 1 |
| 14 | Primary malignant bone tumors-recent de-velopments 显示文摘 | Hameed M Dorfman H | 2011 | Semin Diagn Pathol2011，28，1： | 1 |
| 15 | Robust control with unknown dynamic estimation for multi-axial piezoelectric actuators with coupled dynamics显示文摘 | Hamed G Rezaei S M Zareinejad M | 2012 | Comptes Rendus Mecanique2012，340，9： | 1 |
| 16 | Short communication expansion of cavities in layered elastic system显示文摘 | Sayed S M Hamed M A | 1987 | Intenational Journal for Numerical and Analytical Methods in Geomechanics1987，，1： | 1 |
| 17 | Semi-automatic liver tumor segmentation with hidden markov measure field model and non-parametric distribution estimation显示文摘 | HAME Y POLLARI M | | 0，，01： | 1 |
| 18 | Effect of preparation conditions of oil palm fronds activated carbon on adsorption of bentazon from aqueous soIutions显示文摘 | Salman J M Hameed B H | 2010 | Journal of Hazardous Materials2010，3，1： | 1 |
| 19 | 显示文摘 | Auta M Ern L M Hameed B H | 2014 | Journal of Analytical and Applied Pyrolysis2014，107，： | 1 |
| 20 | Condition monitoring and fault detection of wind turbines and related algorithms:A review显示文摘 | Hameed Z Hong Y S Cho Y M | 2009 | Renewable and Sustainable Energy Reviews2009，13，1： | 1 |
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