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| 1 | 基于小尺度五普数据的南京旧城区社会空间分异研究显示文摘尽管第五次人口普查所反映的社会空间结构特征已经是12 a前的事实,国内外学者也针对2000年的中国第五次人口普查数据做了一定的研究,但是,此类研究要么局限于全域性社会空间统计分析;要么限于县区、街道尺度展开的局域性地理空间分析研究。居委会(社区)这一核心统计尺度的普查数据一直没有被有效地挖掘利用。以南京旧城区为研究案例,首次通过匹配内城区居委会地图和第五次人口普查长短表数据,深度挖掘、揭示居委会尺度下的南京旧城区社会空间隔离特征,并指出:①新世纪南京市城市社会空间转型与分异是计划体制时期社会空间建构力量与市场分化力量混合的结果,相对于上海、北京和广州而言,南京城市制度性力量显示了强劲的路径依赖特征、学习性与适应性;②小尺度社会空间分析挖掘出大尺度无法辨析的学区中产阶层化(jiaoyufication)区域和转型期崛起的新城市精英社区。 | 吴启焰 吴小慧 Chen Guo Hammel J D 刘咏梅 刘丹 | 2013 | 地理科学2013，33，10： | 30 |
| 2 | Stromal expression of SPARC in pancreatic adenocarcinoma显示文摘 | Cindy Neuzillet Annemila? Tijeras-Raballand Jér?me Cros Sandrine Faivre Pascal Hammel Eric Raymond | 2013 | Cancer and Metastasis Reviews (-)2013，，3： | 4 |
| 3 | Socio-spatial differentiation and residential segregation in the Chinese city based on the 2000 community-level census data: A case study of the inner city of Nanjing显示文摘 | Qiyan Wu Jianquan Cheng Guo Chen Denial J. Hammel Xiaohui Wu | 2014 | Cities2014，，： | 3 |
| 4 | FOLFIRI regimen in metastatic pancreatic adenocarcinoma resistant to gemcitabine and platinum-salts显示文摘AIM: To evaluate the efficacy and safety of the FOLFIRI regimen in patients with metastatic pancreatic adenocarcinoma (PAC) after the failure of gemcitabine and platinum salts. METHODS: All consecutive patients with histologically confirmed, metastatic PAC and World Health Organiza-tion performance status (PS) ≤ 2 received FOLFIRI-1 [irinotecan 180 mg/m2 on day 1 and leucovorin 400 mg/m2 followed by 5-fluorouracil (5-FU) 400 mg/m2 bolus, then 5-FU 2400 mg/m2 as a 46-h infusion, biweekly] or FOLFIRI-3 (irinotecan 100 mg/m2 on day 1 and leucovorin 400 mg/m2, then 5-FU 2400 mg/m2 as a 46-h infusion and irinotecan 100 mg/m2 repeated on day 3, biweekly) after failure of gemcitabine and platinum-based chemotherapies as a systematic policy in two institutions between January 2005 and May 2010. Tumor response, time to progression (TTP), overall survival rate (OS) and grade 3-4 toxicities were retrospectively studied. Subgroup analyses were performed to search for prognostic factors. RESULTS: Sixty-three patients (52.4% male, median age 59 years) were analyzed. Among them, 42.9% were PS 0, 38.1% were PS 1 and 19.0% were PS 2. Fifty one patients (81.0%) had liver metastases. Before the FOLFIRI regimen, patients had received 1 line (n = 19), 2 lines (n = 39) or 3 lines (n = 5) of chemotherapy. Median TTP obtained with the line before FOLFIRI was 3.9 mo (95% CI: 3.4-5.3 mo). A total of 480 cycles was completed (median: 6 cycles, range: 1-51 cycles). The main reason for discontinuing FOLFIRI was tumor progression (90.3%). Tumor control was achieved in 25 patients (39.7%) (partial response: n = 5, stable disease: n = 20) with FOLFIRI. Median TTP was 3.0 mo (95% CI: 2.1-3.9 mo) and median OS was 6.6 mo (95% CI: 5.3-8.1 mo). Dose adaptation was required in 36 patients (57.1%). Fifteen patients (23.8%) had grade 3-4 toxicities, mainly hematological (n = 11) or digestive (n = 4). Febrile neutropenia occurred in 3 patients. There was no toxic death. PS 2 was significantly associated with poor TTP [hazard ratio (HR): 16.036, P < 0.0001] and OS (HR: 4.003, P = 0.004). CONCLUSION: The FOLFIRI regimen had an acceptable toxicity and an interesting efficacy in our study, limited to patients in good condition (PS 0-1). | Cindy Neuzillet Olivia Hentic Benot Rousseau Vinciane Rebours Léla Bengrine-Lefèvre Franck Bonnetain Philippe Lévy Eric Raymond Philippe Ruszniewski Christophe Louvet Pascal Hammel | 2012 | World Journal of Gastroenterology2012，18，33： | 3 |
| 5 | Endoscopic ultrasound-guided fine-needle aspiration biopsy coupled with KRAS mutation assay to distinguish pancreatic cancer from pseudotumoral chronic pancreatitis显示文摘 | B. Bournet A. Souque P. Senesse E. Assenat M. Barthet N. Lesavre A. Aubert D. O’Toole P. Hammel P. Levy P. Ruszniewski M. Bouisson J. Escourrou P. Cordelier L. Buscail | 2009 | Endoscopy2009，，06： | 2 |
| 6 | Natural History of Intraductal Papillary Mucinous Tumors of the Pancreas: Actuarial Risk of Malignancy显示文摘 | Philippe Lévy Vincent Jouannaud Dermot O’Toole Anne Couvelard Marie Pierre Vullierme Laurent Palazzo Alain Aubert Philippe Ponsot Alain Sauvanet Frédérique Maire Olivia Hentic Pascal Hammel Philippe Ruszniewski | 2006 | Clinical Gastroenterology and Hepatology2006，，4： | 2 |
| 7 | Role of endoscopic ultrasound in the screening and follow-up of high-risk individuals for familial pancreatic cancer显示文摘Managing familial pancreatic cancer(FPC)is challenging for gastroenterologists,surgeons and oncologists.High-risk individuals(HRI)for pancreatic cancer(PC)(FPC or with germline mutations)are a heterogeneous group of subjects with a theoretical lifetime cumulative risk of PC over 5%.Screening is mainly based on annual magnetic resonance imaging(MRI)and endoscopic ultrasound(EUS).The goal of screening is to identify early-stage operable cancers or high-risk precancerous lesions(pancreatic intraepithelial neoplasia or intraductal papillary mucinous neoplasms with high-grade dysplasia).In the literature,target lesions are identified in 2%-5%of HRI who undergo screening.EUS appears to provide better identification of small solid lesions(0%-46%of HRI)and chronicpancreatitis-like parenchymal changes(14%-77%of HRI),while MRI is probably the best modality to identify small cystic lesions(13%-49%of HRI).There are no specific studies in HRI on the use of contrast-enhanced harmonic EUS.EUS can also be used to obtain tissue samples.Nevertheless,there is still limited evidence on the accuracy of imaging procedures used for screening or agreement on which patients to treat.The cost-effectiveness of screening is also unclear.Certain new EUS-related techniques,such as searching for DNA abnormalities or protein markers in pancreatic fluid,appear to be promising. | Diane Lorenzo Vinciane Rebours Frédérique Maire Maxime Palazzo Jean-Michel Gonzalez Marie-Pierre Vullierme Alain Aubert Pascal Hammel Philippe Lévy Louis de Mestier | 2019 | World Journal of Gastroenterology2019，25，34： | 2 |
| 8 | Risk and Location of Cancer in Patients With Preoperative Colitis-Associated Dysplasia Undergoing Proctocolectomy显示文摘 | Ravi P. Kiran Usama Ahmed Ali Pasha J. Nisar Wisam Khoury Jinyu Gu Bo Shen Feza H. Remzi Jeffrey P. Hammel Ian C. Lavery Victor W. Fazio John R. Goldblum | 2014 | Annals of Surgery2014，，2： | 2 |
| 9 | Multi-screening approach to monitor and quantify 42 antibiotic residues in honey by liquid chromatography–tandem mass spectrometry显示文摘 | Yves-Alexis Hammel Rayane Mohamed Eric Gremaud Marie-Hélène LeBreton Philippe A. Guy | 2007 | Journal of Chromatography A2007，，1： | 2 |
| 10 | Do numerieal orbits of chaotic dynamical proeess represent true orbits显示文摘 | Grebogi C Hammel S M Yorke J A | 1987 | J Complexity1987，3，2： | 1 |
| 11 | Evolutionary computation: Comments on history and currentstate显示文摘 | H-P Schwefel | 1997 | IEEE Transactions on Evolutionary Computation1997，1，1： | 1 |
| 12 | Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex显示文摘 | HAMMEL M YU Y MAHANEY B L | 2010 | J Biol Chem2010，285，2： | 1 |
| 13 | Observability requirements for three-mention tracking via angle measurements显示文摘 | HAMMEL S E AIDALA V J | 1985 | IEEE Transaction On Aerospace and Electronic Systems1985，21，2： | 1 |
| 14 | Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: results of a GERCOR and GISCAD phase Ⅲ trial显示文摘 | Louvet C Labianca R Hammel P | 2005 | J Clin Oncol2005，23，15： | 1 |
| 15 | Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer:results of a GERCOR and GISCAD phase Ⅲ trial显示文摘 | Louvet C Labianca R Hammel P | 2005 | Clin Oncol2005，23，15： | 1 |
| 16 | Glandular tuberculosis as the cause of dysphagia显示文摘 | WestergaardNielsenM Hammel svangPedersen B | 2012 | Ugeskrift for Laeger2012，174，44： | 1 |
| 17 | Evolutionary Computation:Comments on the History and Current state显示文摘 | T Back U Hammel H-P Schwefel | 1997 | IEEE Trans on Neural Networks1997，1，1： | 1 |
| 18 | The localizing value of ictal EEG in focal epilepsy显示文摘 | Foldvary N Klem G Hammel J | 2001 | Neurology2001，57，11： | 1 |
| 19 | Comparison between different strategies of covalent attachment of DNA to glass surfaces to build DNA microarrays显示文摘 | Zammatteo N Jeanmart L Hammels S | 2000 | Analytical Biochemistry2000，280，： | 1 |
| 20 | Evolutionary Computation: Comments on the History and Current State 显示文摘 | Back T Hammel U Schwefel H P | 1997 | IEEE Transactions on Evolutionary Computation1997，1，1： | 1 |
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