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254篇 您的检索式：作者名="Hamilton W J"

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	题名	作者	年代	出处	被引量
1	Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.	Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele	2009	World Journal of Gastroenterology2009，15，10：	20
2	Antisense gene that inhibits synthesis of the hormone ethylene in transgenic plant 显示文摘	Hamilton A J Yycett G W Grierson D	1990	Nature1990，346，：	2
3	Maglignancy and deep vein thrombosis 显示文摘	Barett J Hamilton W	2006	Br J Gen Pract2006，56，530：	1
4	Antisense gene that inhibit synthesis of hormone ethylene in transgenic plants 显示文摘	Hamilton A J Lyett G W Grierson D	1990	Nature1990，346，6281：	1
5	Simulation of flexible-link manipulators applying sequential integration method 显示文摘	Chang L W Hamilton J F	1991	Journal of dynamic systems measurement and control1991，113，：	1
6	Evidence for a male-produced sex pheromone in the western flower thrips Frankliniella occidentals显示文摘	Kirk W D J Hamilton J G C		0，，01：	1
7	Mierofibrillated cellulose : morphology and accessibility 显示文摘	Herrick F W Casebier R L Hamilton J K	1983	Journal of Applied Poly- mer Science1983，37，2：	1
8	Natural occurrences of ochratoxicosis in poultry显示文摘	Hamilton P A T B Huff W E Harris J R A Y	1982	Poultry Science1982，61，9：	1
9	Optical propertiesof cubic SiC:luminescence of nitrogen-exciton complexes,and interband absorption显示文摘	Choyke W J Hamilton D R Patrick L	1964	Physical Review1964，133，4：	1
10	Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘	Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R	2009	Journal of Bacteriology2009，191，16：	1
11	Acousticand other physical properties of shallow-water sediments offSan Diego显示文摘	HAMILTON E L MENARD H W SHIPEX C J 1956	1956	The Journal of the Acoustical Society ofAmerica1956，28，：	1
12	Excess of nonparental bands in offspring from known pedigrees assayed using RAPD PCR显示文摘	Reidy M F Hamilton W J Aquadro C F	1992	Nucleic Acids Res1992，20，：	1
13	Antisense gene that inhibits synthesis of the hormone ethylene in transgenic plant 显示文摘	Hamilton A J Lycett G W Grierson D	1990	Nature1990，346，：	1
14	Commercial Application of Continuous Oxygen in Iron Cupolas显示文摘	Carlson R Hamilton J A and Koepplin W J	1966	AFS Transactions1966，74，：	1
15	Antibiotic Activity of Natural Product:Propolis显示文摘	Brumfitt W Hamilton M J Franklin I	1990	Microbios1990，62，：	1
16	Maglignancy and deep vein thrombosis显示文摘	Barett J Hamilton W	2006	Br J Gen Pract2006，56，530：	1
17	Nitrogen fixation in Canadian precarnbrian shield lakes显示文摘	FLETT R J SCHINDER D W HAMILTON R D	1980	Canadian Journal of Fisheries and Aquatic Sciences1980，37，3：	1
18	Microfibrillated cellulose: morphology and accessibility显示文摘	Herrick F W Casebier R L Hamilton J K	1983	Journal of Applied Polymer Science: Applied Polymer Symposium1983，37，9：	1
19	显示文摘	Raich W J Hamilton C S	1957	J Am Chem Soc1957，79，：	1
20	Free rotation of methyl groups in dimethyltin difluoride显示文摘	RUSH J J HAMILTON W C	1966	Inorg Chem1966，5，12：	1

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