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3篇 您的检索式:作者名="Hanjing Peng"
    题名 作者 年代 出处 被引量
1Increased FoxM1 expression is a target for metformin in the suppressionof EMT in prostate cancer显示文摘Yiru Wang Binwei Yao Yu Wang Mingbo Zhang Shuai Fu Hanjing Gao Ruiyun Peng Lingqiang Zhang Jie Tang 2014International Journal of Molecular Medicine2014,,6:1
2Dynamic modeling of ultra-precision fly cutting machine tool and the effect of ambient vibration on its tool tip response显示文摘The dynamic performances of an ultra-precision fly cutting machine tool(UFCMT)has a dramatic impact on the quality of ultra-precision machining.In this study,the dynamic model of an UFCMT was established based on the transfer matrix method for multibody systems.In particular,the large-span scale flow field mesh model was created;and the variation in linear and angular stiffness of journal and thrust bearings with respect to film thickness was investigated by adopting the dynamic mesh technique.The dynamic model was proven to be valid by comparing the dynamic characteristics of the machine tool obtained by numerical simulation with the experimental results.In addition,the power spectrum density estimation method was adopted to simulate the statistical ambient vibration excitation by processing the ambient vibration signal measured over a long period of time.Applying it to the dynamic model,the dynamic response of the tool tip under ambient vibration was investigated.The results elucidated that the tool tip response was significantly affected by ambient vibration,and the isolation foundation had a good effect on vibration isolation.Jianguo Ding Yu Chang Peng Chen Hui Zhuang Yuanyuan Ding Hanjing Lu Yiheng Chen 2020International Journal of Extreme Manufacturing2020,2,2:0
3BET family protein degraders poised to join the senolytic arsenal显示文摘In a recent study published in Nature Communications,Wakita et al.identified BET family protein degrader(BETd)as a novel senolytic drug through high-throughput screening and biofunctional assays.1 BETd preferentially eliminated senescent cells by targeting nonhomologus end joining(NHEJ)and autophagy and significantly reduced tumor growth in vivo,suggesting that BETd could be used as a new therapy against cancer and agerelated disease(Fig.1).Zufeng Guo Hanjing Peng Yongmei Xie 2020Signal Transduction and Targeted Therapy2020,5,1:0
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