|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A deep learning-enabled portable imaging flow cytometer for cost-effective, highthroughput, and label-free analysis of natural water samples显示文摘We report a deep learning-enabled field-portable and cost-effective imaging flow cytometer that automatically captures phase-contrast color images of the contents of a continuously flowing water sample at a throughput of 100 mL/h.The device is based on partially coherent lens-free holographic microscopy and acquires the diffraction patterns of flowing micro-objects inside a microfluidic channel.These holographic diffraction patterns are reconstructed in real time using a deep learning-based phase-recovery and image-reconstruction method to produce a color image of each micro-object without the use of external labeling.Motion blur is eliminated by simultaneously illuminating the sample with red,green,and blue light-emitting diodes that are pulsed.Operated by a laptop computer,this portable device measures 15.5 cm×15 cm×12.5 cm,weighs 1 kg,and compared to standard imaging flow cytometers,it provides extreme reductions of cost,size and weight while also providing a high volumetric throughput over a large object size range.We demonstrated the capabilities of this device by measuring ocean samples at the Los Angeles coastline and obtaining images of its micro-and nanoplankton composition.Furthermore,we measured the concentration of a potentially toxic alga(Pseudo-nitzschia)in six public beaches in Los Angeles and achieved good agreement with measurements conducted by the California Department of Public Health.The cost-effectiveness,compactness,and simplicity of this computational platform might lead to the creation of a network of imaging flow cytometers for largescale and continuous monitoring of the ocean microbiome,including its plankton composition. | Zoltán Gӧrӧcs Miu Tamamitsu Vittorio Bianco Patrick Wolf Shounak Roy Koyoshi Shindo Kyrollos Yanny Yichen Wu Hatice Ceylan Koydemir Yair Rivenson Aydogan Ozcan | 2018 | Light(Science & Applications)2018，7，1： | 14 |
| 2 | Primary and secondary hyperoxaluria: Understanding the enigma显示文摘Hyperoxaluria is characterized by an increased urinary excretion of oxalate. Primary and secondary hyperoxaluria are two distinct clinical expressions of hyperoxaluria. Primary hyperoxaluria is an inherited error of metabolism due to defective enzyme activity. In contrast, secondary hyperoxaluria is caused by increased dietary ingestion of oxalate, precursors of oxalate or alteration in intestinal microflora. The disease spectrum extends from recurrent kidney stones, nephrocalcinosis and urinary tract infections to chronic kidney disease and end stage renal disease. When calcium oxalate burden exceeds the renal excretory ability, calcium oxalate starts to deposit in various organ systems in a process called systemic oxalosis. Increased urinary oxalate levels help to make the diagnosis while plasma oxalate levels are likely to be more accurate when patients develop chronic kidney disease. Definitive diagnosis of primary hyperoxaluria is achieved by genetic studies and if genetic studies prove inconclusive, liver biopsy is undertaken to establish diagnosis. Diagnostic clues pointing towards secondary hyperoxaluria are a supportive dietary history and tests to detect increased intestinal absorption of oxalate. Conservative treatment for both types of hyperoxaluria includes vigorous hydration and crystallization inhibitors to decrease calcium oxalate precipitation. Pyridoxine is also found to be helpful in approximately 30% patients with primary hyperoxaluria type 1. Liver-kidney and isolated kidney transplantation are the treatment of choice in primary hyperoxaluria type 1 and type 2 respectively. Data is scarce on role of transplantation in primary hyperoxaluria type 3 where there are no reports of end stage renal disease so far. There are ongoing investigations into newer modalities of diagnosis and treatment of hyperoxaluria. Clinical differentiation between primary and secondary hyperoxaluria and further between the types of primary hyperoxaluria is very important because of implications in treatment and diagnosis. Hyperoxaluria continues to be a challenging disease and a high index of clinical suspicion is often the first step on the path to accurate diagnosis and management. | Bhavna Bhasin Hatice Melda ürekli Mohamed G Atta | 2015 | World Journal of Nephrology2015，4，2： | 13 |
| 3 | The effect of co-occurring inorganic solutes on the removal of arsenic(V)from water using cationic surfactant micelles and an ultrafihration membrane显示文摘 | ERDOGAN E HATICE G ALAN F | 2005 | Desalination2005，181，13： | 1 |
| 4 | Use of surfactants to remove water-based inks from plastic film:effect of calcium ion concentration and length of surfactant hydrophobe显示文摘 | Hatice G John F S Sherril D C | 2004 | Colloid Polymer Science2004，283，： | 1 |
| 5 | Use ol surlactants to removewater-based inks from plastic film: effect of calcium ionconcentration and length of surfactant hydrophobe 显示文摘 | Hatice G John F S Sherril D C | 2004 | ColloidPolymer Science2004，283，： | 1 |
| 6 | Development of EST ‐ SSR markers for diversity and breeding studies in opium poppy显示文摘 | Hatice ?elale Ibrahim ?elik Visam Gültekin Jens Allmer Sami Do?anlar Anne Frary | 2013 | Plant Breed2013，，3： | 1 |
| 7 | Changes in microbiological and chemical characteristics of an artisanal Turkish white cheese during ripening显示文摘 | ZUBEYDE O AYNUR G K HATICE A | 2006 | Swiss Society of Food Science and Technology2006，39，： | 1 |
| 8 | Diameters of the common bile duct in adults and postcholecystectomy patients: A study with 64-slice CT显示文摘 | Senem Senturk Tugba Cezlan Miroglu Aslan Bilici Hatice Gumus Rojbin Ceylan Tekin Faysal Ekici Güven Tekbas | 2010 | European Journal of Radiology2010，，： | 1 |
| 9 | Goblet cell carcinoid of the appendix and mixed adenoneuroendocrine carcinoma: Report of three cases显示文摘Neuroendocrine neoplasms are the most common epithelial tumors among appendix tumors. Appendix tumors that are completely or partially composed of neuroendocrine cells are divided into two categories: Classic carcinoid tumors and goblet cell carcinoid tumors(GCCT). They are known to progress more aggressively than classic(neuro) endocrine tumors. In this study, three cases with acute appendicitis symptoms are presented, including their clinical and histopathological findings. Microscopic examination detected GCCT in two cases and mixed adenoneuroendocrine carcinoma in one case, in addition to acute appendicitis. | Hatice Karaman Fatma Senel Mustafa Güreli Turan Ekinci Omer Topuz | 2017 | World Journal of Gastrointestinal Oncology2017，9，7： | 1 |
| 10 | 3-T MRI of the biliary tract variations显示文摘 | Hakan ?nder Muhammed S?dd?k ?zdemir Güven Tekba? Faysal Ekici Hatice Gümü? Aslan Bilici | 2013 | Surgical and Radiologic Anatomy2013，，2： | 1 |
| 11 | Particulated juvenile articular cartilage graft(DeNovo NT Graft) for treatment of osteochondral lesions of the talus显示文摘 | Hatic S O 2nd Berlet G C | 2010 | Foot Ankle Spe2010，3，6： | 1 |
| 12 | Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic an- hydrase isozymes 显示文摘 | Rahmi K Metin B Hatice G | 2009 | Bioorg Med Chem2009，17，9： | 1 |
| 13 | Concha bullosa types: their rela- tionship with sinusitis, ostiomeatal and frontal recess disease显示文摘 | Hatioglu Hatice G Cetin | 2005 | Diagn Interv Radiol2005，11，3： | 1 |
| 14 | Self-consolidating characteristics of concrete composites including rounded fine and coarse fly ash lightweight aggregates显示文摘 | Mehmet Geso?lu Erhan Güneyisi Turan ?zturan Hatice ?znur ?z Diler Sabah Asaad | 2014 | Composites Part B2014，，： | 1 |
| 15 | The Efficacy of Octreotide in Pancreatic and Intestinal Changes: Radiation-Induced Enteritis in Animals显示文摘 | Vakur Olga? PhD Ye?im Erbil Umut Barbaros MD Serdar ?ztezcan Murat Giri? MSc Hakan Kaya MD Hatice Bilge Semra Güler PhD Gül?in Toker | 2006 | Digestive Diseases and Sciences2006，，1： | 1 |
| 16 | Magnetic resonance imaging of the condylar growth pattern and disk position after chin cup therapy:a preliminary study显示文摘 | Hatice G Gokmen K | 2005 | Angle Orthod2005，75，4： | 1 |
| 17 | Magnetic resonace imaging assessment of positional relationship between the disk and condyle in asymptomatic young adult mandibular prognathism 显示文摘 | Hatice G | 2003 | Angle Orthod2003，73，5： | 1 |
| 18 | Output- associative RVM regression for dimensional and continuous emotion prediction显示文摘 | MIHALIS A N HATICE G and MAJA P | 2012 | Image and Vision Computing2012，30，3： | 1 |
| 19 | Identification and bioactivity of native strains of Bacillus thuringiensis from grain-related habitats in Turkey显示文摘 | ?zgür Apaydin ?elenk ??nar Ferit Turanli ?ebnem Harsa Hatice Güne? | 2008 | Biological Control2008，，1： | 1 |
| 20 | Evaluation of a card test for procaleitonin in continuous ambulatory peritoneal dialysis peritoni-tis显示文摘 | Fatma MY G(u)lsen Y Hatice A | 2007 | Ann Clinic Biochem2007，44，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员