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| 1 | 203例农村有偿献血感染HIV患者抑郁障碍及生活质量调查显示文摘目的:调查通过献血途径感染人类免疫缺陷病毒(HIV)的203例患者的情绪状况及生活质量。方法:采用贝克抑郁问卷、复合性国际诊断用检查提纲和SF-36对203例通过献血途径感染HIV的患者(HIV阳性组)及年龄、性别和受教育年限相匹配的198例HIV阴性献血者进行调查。结果:①HIV阳性组献血次数多于HIV阴性组(52.2±95.4/13.2±23.9,P<0.001),已婚者少于HIV阴性组(88.6%/ 95.5%,P=0.020),丧偶者多于HIV阴性组(10.9%/4.5%,P=0.020),失业率高于HIV阴性组(21.7%/4.0%,P<0.001),前一年全年工作时间少于HIV阴性组(5.0±3.5/7.5±3.0,P<0.001),家庭月收入低于HIV阴性组(476.3±412.7/709.9±513.7,P<0.001)。②HIV阳性组被诊断为获得性免疫缺陷综合征(AIDS)者占56.6%。HIV阳性组抑郁症的终生患病率为13.8%,HIV阴性组的终生患病率为5.1%。HIV阳性组的抑郁总分(11.3±11.3/6.6±9.6)、躯体(3.3±2.9/2.0±2.6)和非躯体因子分(8.0±8.8/4.6±7.4)均高于HIV阴性组(P<0.001)。HIV阳性组达轻度抑郁以上者占40.4%。HIV阳性组已制定自杀计划者高于HIV阴性组(8.4%/3.0%,P<0.05)。HIV阳性组总体生理健康(48.3±9.7/ 55.5±7.0)和心理健康(48.8±8.9/55.1±7.8)得分均低于HIV阴性组(P<0.001)。③HIV阳性组的贝克抑郁问卷总分与T细胞亚群CD4细胞计数无显著相关,与总体生理健康及心理健康呈显著负相关(r=- 0.46~0.68,P<0.001)。结论:HIV阳性患者生存状况较差。对HIV阳性感染者而言,抑郁给患者生活质量造成全面的影响,抑郁和自杀风险仍然是需要干预和处理的问题。 | 宁南义 石川 于欣 陈玉芳 吴尊友 Jin Hua Vigil O Cysique LA Franklin DR Grant I Heaton RK | 2008 | 中国心理卫生杂志2008，22，7： | 14 |
| 2 | HIV-associatedneurocognitive disorders before and during the era ofcombination antiretroviral therapy: differences in rates,nature, and predictors 显示文摘 | Heaton RK Franklin DR Ellis RJ | 2011 | J Neurovirol2011，17，1： | 1 |
| 3 | Wisconsin card sorting test manual显示文摘 | Heaton RK | 1981 | Psychologial Assessment Resources1981，，： | 1 |
| 4 | Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders显示文摘 | Masliah E Heaton RK Marcotte TD | 1997 | Ann Neurol1997，42，6： | 1 |
| 5 | Stability and course of neuropsychological deficits in schizophrenia 显示文摘 | Heaton RK Gladsio JA Palmer BW | 2001 | Arch Gen Psychiatry2001，58，1： | 1 |
| 6 | Psychologic effects of continuous and nocturnal oxygen therapy in hypoxemic chronic obstructive pulmonary disease显示文摘 | Heaton RK Grant I McSweeny AJ | 1983 | Arch Intern Med1983，143，： | 1 |
| 7 | HIV associated neuro- ' cognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature and predic tors显示文摘 | Heaton RK Fanklin DR Ellis RJ | 2011 | J Neurovirol2011，17，1： | 1 |
| 8 | Stability and course of neuropsychological deficits in schizophrenia 显示文摘 | Heaton RK Gladsjo JA Palmer BW | 2001 | Arch Gen Psychiatry2001，58，： | 1 |
| 9 | Relationship of neuropsychological status to everyday functioning in healthy and chronically ill persons显示文摘 | McSweeny A J Grant I Heaton RK | 1985 | J Clin Exp Neuropsychol1985，7，： | 1 |
| 10 | Stability and course of neuropsychological deficits in schizophrenia显示文摘 | Heaton RK Gladsjo TA Palmer BW | 2001 | Arch Gen Psychiatry2001，58，1： | 1 |
| 11 | The relationship of neuro-psychological abilities to specific domains of functional capacity inolder schizophrenia patients 显示文摘 | Evans JD Heaton RK Paulsen JS | 2003 | Biol Psychiatry2003，53，： | 1 |
| 12 | Longitudinal studies of cognition and functional outcome in schizophrenia:implications for MATRICS显示文摘 | Green MF Kern Rs Heaton RK | 2004 | Schizophr Res2004，72，1： | 1 |
| 13 | Life quality of patients with chronic obstructive pulmonary disease显示文摘 | Sweeny AJM Grant I Heaton RK | 1982 | Arch Inter Med1982，，142： | 1 |
| 14 | Longitudinal studies of cognition and functional outcome in schizophrenia:implications for MATRICS显示文摘 | Green MF Kern RS Heaton RK | 2004 | Schizophr Res2004，72，： | 1 |
| 15 | Ixtngitudinal studies of cognition andfunctionaloutcome in srhizophreniarim plications for MATRICS显示文摘 | Green MF Kem RS Heaton RK | 2004 | SchizophRes2004，72，1： | 1 |
| 16 | White matter dementia in chronic toluene abuse 显示文摘 | FiLley CM Heaton RK Rosenberg NL | 1990 | Neurology1990，40，31： | 1 |
| 17 | Stability and course of neuropsychological deficits in schizophrenia显示文摘 | Heaton RK Gladsjo JA Palmer BW | 2001 | Arch Gen Psychiatry2001，58，： | 1 |
| 18 | Psychologic effects ofcontinuous and nocturnal Oxygen therapy in hypoxemic chronicobstructive pulmonary disease 显示文摘 | Heaton RK Grant I Mcsweeny AJ | 1983 | Archives of internal medicine1983，143，10： | 1 |
| 19 | Is it possible to be schizophrenic yet neuropsychologically normal? 显示文摘 | Palmer BW Heaton RK Paulsen JS | 1997 | Neuropsy- chology1997，11，3： | 1 |
| 20 | HIV-associated neu- rocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors 显示文摘 | Heaton RK Franklin DR Ellis R J | 2011 | J Neurovirol2011，17，： | 1 |
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