|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Should antibiotics be administered before arthroscopic knee surgery? A systematic review of the literature显示文摘AIM To explore the current evidence surrounding the administration of prophylactic antibiotics for arthroscopic knee surgery. METHODS Databases were searched from inception through May of 2018 for studies examining prophylactic antibiotic use and efficacy in knee arthroscopy. Studies with patient data were further assessed for types of arthroscopic procedures performed,number of patients in the study,use of antibiotics,and outcomes with the intention of performing a pooled analysis. Data pertaining to 'deep tissue infection' or 'septic arthritis' were included in our analysis. Reported data on superficial infection were not included in our data analysis. For the pooled analysis,a relative risk ratio was calculated and χ~2 tests were used to assess for statistical significance between rates of infection amongst the various patient groups. Post hoc power analyses were performed to compute the statistical power obtained from our sample sizes. Number needed to treat analyses were performed for statistically significant differences by dividing 1 by the difference between the infection rates of the antibiotic and no antibiotic groups. An alpha value of 0.05 was used for our analysis. Study heterogeneity was assessed by Cochrane's Q test as well as calculation of the I^2 value.RESULTS A total of 49682 patients who underwent knee ar-throscopy for a diverse set of procedures across 19 studies met inclusion critera for pooled analysis. For those not undergoing graft procedures,there were 27 cases of post-operative septic arthritis in 34487 patients(0.08%) who received prophylactic antibiotics and 16 cases in 10911(0.15%) who received none [risk ratio(RR) = 0.53,95% confidence interval(CI): 0.29-0.99,P = 0.05]. A sub-group analysis in which bony procedures were excluded was performed which found no significant difference in infection rates between patients that received prophylactic antibiotics and patients that did not(P > 0.05). All anterior cruciate ligament reconstruction studies used prophylactic antibiotics,but two studies investigating the effect of soaking the graft in vancomycin in addition to standard intravenous(IV) prophylaxis were combined for analysis. There were 19 cases in 1095 patients(1.74%) who received IV antibioitics alone and no infections in 2034 patients who received IV antibiotics and had a vancomycin soaked graft(RR = 0.01,95%CI: 0.001-0.229,P < 0.01).CONCLUSION Prophylactic antibiotics are effective in preventing septic arthritis following simple knee arthroscopy. In procedures involving graft implantation,graft soaking reduces the rate of infection. | John Carney Nathanael Heckmann Erik N Mayer Ram K Alluri Carleton Thomas Vangsness George F Hatch Ⅲ Alexander E Weber | 2018 | World Journal of Orthopedics2018，9，11： | 2 |
| 2 | Molecular mechanism of stop codon recognition by eRF1 : a wobble hypothesis for peptide anticodons 显示文摘 | Muramatsu T Heckmann K Kitanaka C | 2001 | FEBS Lett2001，488，3： | 1 |
| 3 | Nuclear processes in Euplotes octocarinatus during conjugation显示文摘 | Kuhlmann HW Heckmann K | 1991 | Eur J Protistol1991，26，34： | 1 |
| 4 | High-strength large-diameter pipe for long-distance high-pressure gas pipelines显示文摘 | Graef M K Hillenbrand H G Heckmann C J | 2004 | International Journal of Offshore and Polar Engineering2004，14，1： | 1 |
| 5 | The macronuclear gamma-tubulin-encoding gene of Euplotes octocarinatus contains two introns and an in-frame TGA显示文摘 | Liang A Heckmann K | 1993 | Gene1993，136，12： | 1 |
| 6 | Noise adaptive stream weighting in audio-visual speech recognition显示文摘 | Heckmann M Berthommier F Kroschel K | 2002 | EUR- ASIP Journal on Applied Signal Processing2002，2002，1： | 1 |
| 7 | Analysis of micronuclear,macronuclear and cDNA sequences encoding the regulatory subunit of cAMP-dependent protein kinase of Euplotes octocarinatus:evidence for a ribosomal frameshift显示文摘 | Tan M Heckmann K Brunen-Nieweler C | 2001 | J Eukaryot Microbiol2001，48，1： | 1 |
| 8 | A single-blinded trial of methotrexate versus azathioprine as steroid-sparing agents in gener- alized myasthenia gravis 显示文摘 | Heckmann JM Rawoot A Bateman K | 2011 | BMC Neuro12011，11，： | 1 |
| 9 | Isolation of Micronuclei from Euplotes Octocarinatus and Iidentification of An internal Eliminated Sequence in the Micronuclear Gene Encoding γ-tubulin2显示文摘 | TAN M BRUNEN-Nieweler C HECKMANN K | 1999 | Eur J Protistol1999，35，： | 1 |
| 10 | Vascu-lar abnormalities in reflex sympathetic dystrophy (CRPSI):mechanisms and diagnostic value 显示文摘 | Wasner G Schattschneider J Heckmann K | 2001 | Brain2001，124，3： | 1 |
| 11 | High- strength large-diameter pipe for long-distance high-pressure gas pipelines 显示文摘 | Graef M K Hillenbrand H G Heckmann C J | 2004 | International Journal of Offshore and Polar Engineering2004，14，1： | 1 |
| 12 | Quasicontinuous domains and the smyth powerdomain显示文摘 | Heckmann R Keimel K | 2013 | Electronic Notes in Theoretical Computer Science2013，298，： | 1 |
| 13 | Ecological integrity of remnant montane forests along an urban gradient in the Sierra Nevada显示文摘 | Heckmann K E Manley P N Schlesinger M D | 2008 | For Ecol Manag2008，255，： | 1 |
| 14 | Analysis of micronuclear, macronuclear and cDNA sequences encoding the regulatory subunit of cAMP-dependent protein kinase of Euplotes octocarinatus : evidence for a ribosomal frameshift 显示文摘 | Tan M Heckmann K Brunen-Nieweler C | 2001 | J Eukaryot Microbiol2001，48，1： | 1 |
| 15 | High-strength large-diameter pipe for long-distance high-pressure gas piplines显示文摘 | Graef M K Hillenbrand H G Heckmann C J | 2004 | International Journal of Offshore and Polar Enginerring2004，14，1： | 1 |
| 16 | Gammar-tubulin is permanently associated with basal bodies in ciliates显示文摘 | LIANG A RUIZ F HECKMANN K | 1996 | Europ Cell Biol1996，，70： | 1 |
| 17 | Molecular mechanism of stop codon recognition by eRFI: a wobble hypothesis for peptide anticodons 显示文摘 | Muramatsu T Heckmann K Kitanaka C | 2001 | FEBS Lett2001，488，3： | 1 |
| 18 | Gamones are secreted in Euplotes octocarinatus via the cortical ampules 显示文摘 | KUSCH J HECKMANN K | 1988 | Europ J Protistol1988，23，： | 1 |
| 19 | UGA is translated as cysteine in pheromone 3 of Euplotes octocarinatus显示文摘 | MEYER F SCHMIDT H J HECKMANN K | 1991 | Proc Natl Acad Sci1991，88，： | 1 |
| 20 | Express of the pheromone 3-encoding gene of Euplotes octocarinatus using a novel bacterial secretion vector显示文摘 | BRUNEN-NIEWELER C MEYER F HECKMANN K | 1994 | Gene1994，150，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员