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| 1 | Favorable lifestyle before diagnosis associated with lower risk of screen-detected advanced colorectal neoplasia显示文摘AIM: To investigate the association between adherence to health recommendations and detection of advanced colorectal neoplasia(ACN) in colorectal cancer(CRC) screening.METHODS: A total of 14832 women and men were invited to CRC screening, 6959 in the fecal immunochemical test arm and 7873 in the flexible sigmoidoscopy arm. These were also sent a self-reported lifestyle questionnaire to be completed prior to their first CRC screening. A lifestyle score was created to reflect current adherence to healthy behaviors in regard to smoking, body mass index, physical activity, alcohol consumption and food consumption, and ranged from zero(poorest) to six(best). Odds ratios(ORs) and 95%CIs were calculated using multivariable logistic regression to evaluate the association between the single lifestyle variables and the lifestyle score and the probability of detecting ACN.RESULTS: In all 6315 women and men completed the lifestyle questionnaire, 3323(53%) in the FIT arm and 2992(47%) in the FS arm. This was 89% of those who participated in screening. ACN was diagnosed in 311(5%) participants of which 25(8%) were diagnosed with CRC. For individuals with a lifestyle score of two, three, four, and five-six, the ORs(95%CI) for the probability of ACN detection were 0.82(0.45-1.16), 0.43(0.28-0.73), 0.41(0.23-0.64), and 0.41(0.22-0.73), respectively compared to individuals with a lifestyle score of zero-one. Of the single lifestyle factors, adherence to non-smoking and moderate alcohol intake were associated with a decreased probability of ACN detection compared to being a smoker or having a high alcohol intake 0.53(0.42-0.68) and 0.63(0.43-0.93) respectively.CONCLUSION: Adopted healthy behaviors were inversely associated with the probability of ACN detection. Lifestyle assessment might be useful for risk stratification in CRC screening. | Markus D Knudsen Thomas de Lange Edoardo Botteri Dung-Hong Nguyen Helge Evensen Chloé B Steen Geir Hoff Tomm Bernklev Anette Hjartaker Paula Berstad | 2016 | World Journal of Gastroenterology2016，22，27： | 3 |
| 2 | Quality of life after curative liver resection: A single center analysis显示文摘AIM: To evaluate quality of life (QoL) after curative liver resection and identify variables associated with decreased QoL. METHODS: From October 2001 to July 2004, 323 patients underwent liver resection. At 3-36 mo after discharge, 188 patients were disease free. QoL was assessed using the Short Form (SF)-12 Health Survey with mental and physical component scales (SF-12 MCS and PCS), supplemented with generic questions concerning pain and liver-specific items. RESULTS: Sixty-eight percent (128/188) returned the questionnaire, which was completed in 75% (96/128) of cases. Median SF-12 PCS and MCS were 46.7 (inter- quartile range: 34.2-53.9) and 54.1 (42.8-58.2). Fifty percent were pain free with a median symptom score of 1.75 (1.38-2.13). PCS was higher after major hepatec-tomy [57% (55/96)] compared to minor resection (P = 0.0049), which represented an improved QoL. QoL was not affected by sex but by age compared to the general German population. MCS was higher after liver surgery for metastatic disease [55.9 (47.5-58.8)] compared to primary carcinoma [49.6 (36.5-55.1)] and benign disease [49.2 (37.7-56.3)] (P = 0.0317). There was no correlation between length of postoperative period and QoL. Pain, def iciencies in everyday life and a high symptom score significantly decreased MCS and PCS. CONCLUSION: Most patients were only marginally affected even after major liver resection; however, minor complications were associated with decreased SF-12 MCS and PCS and need careful attention. | Helge Bruns Kirsten Krtschmer Ulf Hinz Anette Brechtel Monika Keller Markus W Büchler Peter Schemmer | 2010 | World Journal of Gastroenterology2010，16，19： | 2 |
| 3 | Bacte-riocins of propionic acid bacteria 显示文摘 | Helge H Therese F Dag A B | 2002 | EPD Science2002，10，： | 1 |
| 4 | Bacteriocins of propionic acid bacteria 显示文摘 | Helge H Therese F Dag A B | 2002 | EPD Science2002，10，： | 1 |
| 5 | Ultra-thick lithography for advanced packaging and MEMS 显示文摘 | Chad B Rafiqul I Helge L | 2002 | Proceedings of SPIE2002，4690，： | 1 |
| 6 | Studies of plasma membrane fatty acid-binding protein and other lipid-binding proteins in human skeletal muscle显示文摘 | Roepstorff C Helge J and Vistisen B | 2004 | Proceedings of the Nutrition Society2004，63，： | 1 |
| 7 | Pharmaceuticals and personal care products (PPCPs) in surface and treated waters of Louisiana, USA and Ontario, Canada 显示文摘 | Glen R B Helge R Deborah A G | 2003 | Science of the Total Environment2003，311，13： | 1 |
| 8 | Effect of gas composition and gas utilisation on the dynamic response of a proton exchange membrane fuel cell 显示文摘 | Helge Weydahl Steffen Mφller -Hoist Bφrre Bφrresen | 2008 | Journal of Power Sources2008，180，： | 1 |
| 9 | Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects 显示文摘 | Bruun JM Helge JW Richelsen B | 2006 | Am J Physiol Endocrinol Metab2006，290，5： | 1 |
| 10 | Interaction of training and diet on metabolism and endurance during exercise in man 显示文摘 | Helge JW Richter EA Kiens B | 1996 | J Physiol1996，492，1： | 1 |
| 11 | Whole-body fat oxidation determined by graded exercise and indirect calorimetry:a role for muscle oxidation capacity?显示文摘 | Nordby P Saltin B Helge J W | 2006 | Scandinavian Journal of Medicine and Scieence in Sport2006，16，： | 1 |
| 12 | Sensitivity analysis of 18 different potential evapotranspi- ration models to observed climatic change at German climate sta- tions显示文摘 | HELGE B | 2011 | Climatic Change2011，104，72： | 1 |
| 13 | Adaptive slicing using stepwise uniform refinement显示文摘 | Sabourian Emmannel Houser Scott A Bφhn Jan Helge | 1996 | Rapid Portotyping Journal1996，2，4： | 1 |
| 14 | Correspondence of the fine-scale spatial variation in soil chemistry and the herb layer vegetation in beech forests显示文摘 | HELGE B PIT U | 2005 | Forest Ecology and Management2005，210，： | 1 |
| 15 | The use of weightbear- ing radiographs to assess the stability of supination - exter- nal rotation fractures of the ankle 显示文摘 | Martin W Helge B Gerhard F | 2010 | Archives of Orthopae- dic and Trauma Surgery2010，130，5： | 1 |
| 16 | Interleukin-18in plasma and adipose tissue:effects of obesity,insulin resistance,and weight loss显示文摘 | Bruun JM Stallknecht B Helge JW | 2007 | Eur J Endocrinol2007，157，： | 1 |
| 17 | Interstitial glycerol concentrations in human skeletal muscle and adipose tissue during graded exercise显示文摘 | Stal knecht B Kiens B Helge JW | | 0，，04： | 1 |
| 18 | Evaluation of potential bias in observing fish with a DIDSON acoustic camera显示文摘 | Michal T Jaroslava F Helge B | 2014 | Fisheries Research2014，155，4： | 1 |
| 19 | Effects of slow and fast pyrolysis biochar on soil C and N turnover dynamics 显示文摘 | Esben W B Per A Helge E | 2012 | Soil Biology & Biochemistry2012，46，1： | 1 |
| 20 | Impact of a fat - rich diet on endurance in man: role of the dietary period显示文摘 | Helge JW Wulff B Kiens B | 1998 | Med Sci Sports Exerc1998，30，3： | 1 |
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