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| 1 | Recent progress in organic solar cells(PartⅠmaterial science)显示文摘During past several years,the photovoltaic performances of organic solar cells(OSCs)have achieved rapid progress with power conversion efficiencies(PCEs)over 18%,demonstrating a great practical application prospect.The development of material science including conjugated polymer donors,oligomer-like organic molecule donors,fused and nonfused ring acceptors,polymer acceptors,single-component organic solar cells and water/alcohol soluble interface materials are the key research topics in OSC field.Herein,the recent progress of these aspects is systematically summarized.Meanwhile,the current problems and future development are also discussed. | Yahui Liu Bowen Liu Chang-Qi Ma Fei Huang Guitao Feng Hongzheng Chen Jianhui Hou Lingpeng Yan Qingya Wei Qun Luo Qinye Bao Wei Ma Wei Liu Weiwei Li Xiangjian Wan Xiaotian Hu Yanchun Han Yaowen Li Yinhua Zhou Yingping Zou Yiwang Chen Yongfang Li Yongsheng Chen Zheng Tang Zhicheng Hu Zhi-Guo Zhang Zhishan Bo | 2022 | Science China Chemistry2022，65，2： | 5 |
| 2 | Recent progress in organic solar cells(PartⅡdevice engineering)显示文摘1 Introduction Organic solar cells(OSCs)belong to a multidisciplinary field composed of chemistry,materials science,physics,engineering,etc.For a better reviewing of this field,we briefly divide the research field of OSCs into two parts:material science and device engineering.In our previous review,the material science part of OSCs,including conjugated polymer donors and acceptors,small molecular donors and acceptors. | Yahui Liu Bowen Liu Chang-Qi Ma Fei Huang Guitao Feng Hongzheng Chen Jianhui Hou Lingpeng Yan Qingya Wei Qun Luo Qinye Bao Wei Ma Wei Liu Weiwei Li Xiangjian Wan Xiaotian Hu Yanchun Han Yaowen Li Yinhua Zhou Yingping Zou Yiwang Chen Yuqiang Liu Lei Meng Yongfang Li Yongsheng Chen Zheng Tang Zhicheng Hu Zhi-Guo Zhang Zhishan Bo | 2022 | Science China Chemistry2022，65，8： | 3 |
| 3 | Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome显示文摘Organization of the genome into euchromatin and heterochromatin appears to be evolutionarily conserved and relatively stable during lineage differentiation.In an effort to unravel the basic principle underlying genome folding,here we focus on the genome itself and report a fundamental role for L1(LINE1 or LINE-1)and B1/Alu retrotransposons,the most abundant subclasses of repetitive sequences,in chromatin compartmentalization.We find that homotypic clustering of L1 and B1/Alu demarcates the genome into grossly exclusive domains,and characterizes and predicts Hi-C compartments.Spatial segregation of L1-rich sequences in the nuclear and nucleolar peripheries and B1/Alu-rich sequences in the nuclear interior is conserved in mouse and human cells and occurs dynamically during the cell cycle.In addition,de novo establishment of L1 and B1 nuclear segregation is coincident with the formation of higher-order chromatin structures during early embryogenesis and appears to be critically regulated by L1 and B1 transcripts.Importantly,depletion of L1 transcripts in embryonic stem cells drastically weakens homotypic repeat contacts and compartmental strength,and disrupts the nuclear segregation of L1-or B1-rich chromosomal sequences at genome-wide and individual sites.Mechanistically,nuclear co-localization and liquid droplet formation of L1 repeat DNA and RNA with heterochromatin protein HP1αsuggest a phase-separation mechanism by which L1 promotes heterochromatin compartmentalization.Taken together,we propose a genetically encoded model in which L1 and B1/Alu repeats blueprint chromatin macrostructure.Our model explains the robustness of genome folding into a common conserved core,on which dynamic gene regulation is overlaid across cells. | J.Yuyang Lu Lei Chang Tong Li Ting Wang Yafei Yin Ge Zhan Xue Han Ke Zhang Yibing Tao Michelle Percharde Liang Wang Qi Peng Pixi Yan Hui Zhang Xianju Bi Wen Shao Yantao Hong Zhongyang Wu Runze Ma Peizhe Wang Wenzhi Li Jing Zhang Zai Chang Yingping Hou Bing Zhu Miguel Ramalho-Santos Pilong Li Wei Xie Jie Na Yujie Sun Xiaohua Shen | 2021 | Cell Research2021，31，6： | 1 |
| 4 | A novel n-type conjugated polymer DOCN-PPV: Synthesis, optical, and electrochemical properties显示文摘 | Zou Yingping Hou Jianhui Yang Chunhe | 2006 | Macromolecules2006，39，26： | 1 |
| 5 | Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrin-targeted drug delivery显示文摘 | Chen Xiaoyuan Plasencia Carmen Hou Yingping | 2005 | Journal of Medical Chemistry2005，48，4： | 1 |
| 6 | MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide显示文摘 | Xiaoyuan Chen Ryan Park Yingping Hou Vazgen Khankaldyyan Ignacio Gonzales-Gomez Michel Tohme James R. Bading Walter E. Laug Peter S. Conti | 2004 | European Journal of Nuclear Medicine and Molecular Imaging2004，，8： | 1 |
| 7 | An Experimental Study on Relationship between the Uptake of Radioiodine(^125I).and Irradiation Dosage in Differential Thyroid Cancer Cells显示文摘 | Zhigang Li Yingping Hou Jing Wang Jinglan Deng | 2006 | Journal of US-China Medical Science2006，3，3： | 0 |
| 8 | Illuminating the structure and dynamics of chromatin by fluorescence labeling显示文摘chromosomal loci 地点和动力学的背景可视化为理解象 DNA 抄写,复制,和修理那样的许多基本 intra 原子的过程是关键的。这里的目的,我们将描述为染色质成像把方法标记的荧光的开发,包括把技术标记在的传统以及新兴的染色质修理并且实时 cells.We 将也讨论当前的问题并且在未来开发和把技术标记的染色质的应用程序提供一个观点。系统的文学搜索用 PubMed 被执行的方法。在过去的 50 年出版的研究为评论被考虑。超过 100 篇文章在这评论被引用。考虑敏感,特性,和空间与时间的分辨率,荧光标记和成像的结果是为染色质可视化的最流行的途径。在所有荧光灯的标记工具之中,染色体编辑的采纳工具例如故事和 CRISPR,为标记和染色质的成像有大潜力。结论尽管把技术标记的很多染色质是可得到的为修理并且实时房间,更多努力仍然清楚地被要求开发把能够非干扰地指向任意的序列允许的方法标记的荧光长期, genomic loci 和染色质的 multiplexing,和高产量的成像组织。新兴的工艺的进展将与单个分子的分辨率在单个房间的水平向染色质的全面描述构画出一个下一代的努力。 | Shipeng Shao Lei Chang Yingping Hou Yujie Sun | 2017 | Frontiers in Biology2017，12，4： | 0 |
| 9 | Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells显示文摘The eukaryotic genome is folded into higher-order conformation accompanied with constrained dynamics for coordinated genome functions.However,the molecular machinery underlying these hierarchically organized three-dimensional(3D)chromatin architecture and dynamics remains poorly understood.Here by combining imaging and sequencing,we studied the role of lamin B1 in chromatin architecture and dynamics.We found that lamin B1 depletion leads to detachment of lamina-associated domains(LADs)from the nuclear periphery accompanied with global chromatin redistribution and decompaction.Consequently,the interchromosomal as well as inter-compartment interactions are increased,but the structure of topologically associating domains(TADs)is not affected.Using live-cell genomic loci tracking,we further proved that depletion of lamin B1 leads to increased chromatin dynamics,owing to chromatin decompaction and redistribution toward nucleoplasm.Taken together,our data suggest that lamin B1 and chromatin interactions at the nuclear periphery promote LAD maintenance,chromatin compaction,genomic compartmentalization into chromosome territories and A/B compartments and confine chromatin dynamics,supporting their crucial roles in chromatin higher-order structure and chromatin dynamics. | Lei Chang Mengfan Li Shipeng Shao Chen Li Shanshan Ai Boxin Xue Yingping Hou Yiwen Zhang Ruifeng Li Xiaoying Fan Aibin He Cheng Li Yujie Sun | 2022 | Protein & Cell2022，13，4： | 0 |
| 10 | CTCF organizes inter-A compartment interactions through RYBP-dependent phase separation显示文摘Chromatin is spatially organized into three-dimensional structures at different levels including A/B compartments, topologically associating domains and loops. The canonical CTCF-mediated loop extrusion model can explain the formation of loops. However, the organization mechanisms underlying long-range chromatin interactions such as interactions between A–A compartments are still poorly understood. Here we show that different from the canonical loop extrusion model, RYBP-mediated phase separation of CTCF organizes inter-A compartment interactions. Based on this model, we designed and verified an induced CTCF phase separation system in embryonic stem cells (ESCs), which facilitated inter-A compartment interactions, improved self-renewal of ESCs and inhibited their differentiation toward neural progenitor cells. These findings support a novel and non-canonical role of CTCF in organizing long-range chromatin interactions via phase separation. | Chao Wei Lumeng Jia Xiaona Huang Jin Tan Mulan Wang Jing Niu Yingping Hou Jun Sun Pengguihang Zeng Jia Wang Li Qing Lin Ma Xinyi Liu Xiuxiao Tang Fenjie Li Shaoshuai Jiang Jingxin Liu Tingting Li Lili Fan Yujie Sun Juntao Gao Cheng Li Junjun Ding | 2022 | Cell Research2022，32，8： | 0 |
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