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| 1 | A concept for multiterawatt fibre lasers based on coherent pulse stacking in passive cavities显示文摘Since the advent of femtosecond lasers,performance improvements have constantly impacted on existing applications and enabled novel applications.However,one performance feature bearing the potential of a quantum leap for high-field applications is still not available:the simultaneous emission of extremely high peak and average powers.Emerging applications such as laser particle acceleration require exactly this performance regime and,therefore,challenge laser technology at large.On the one hand,canonical bulk systems can provide pulse peak powers in the multi-terawatt to petawatt range,while on the other hand,advanced solid-state-laser concepts such as the thin disk,slab or fibre are well known for their high efficiency and their ability to emit high average powers in the kilowatt range with excellent beam quality.In this contribution,a compact laser system capable of simultaneously providing high peak and average powers with high wall-plug efficiency is proposed and analysed.The concept is based on the temporal coherent combination(pulse stacking)of a pulse train emitted from a high-repetition-rate femtosecond laser system in a passive enhancement cavity.Thus,the pulse energy is increased at the cost of the repetition rate while almost preserving the average power.The concept relies on a fast switching element for dumping the enhanced pulse out of the cavity.The switch constitutes the key challenge of our proposal.Addressing this challenge could,for the first time,allow the highly efficient dumping of joule-class pulses at megawatt average power levels and lead to unprecedented laser parameters. | Sven Breitkopf Tino Eidam Arno Klenke Lorenz von Grafenstein Henning Carstens Simon Holzberger Ernst Fill Thomas Schreiber Ferenc Krausz Andreas Tunnermann Ioachim Pupeza Jens Limpert | 2014 | Light(Science & Applications)2014，3，1： | 11 |
| 2 | Watt-scale super-octave mid-infrared intrapulse difference frequency generation显示文摘The development of high-power,broadband sources of coherent mid-infrared radiation is currently the subject of intense research that is driven by a substantial number of existing and continuously emerging applications in medical diagnostics,spectroscopy,microscopy,and fundamental science.One of the major,long-standing challenges in improving the performance of these applications has been the construction of compact,broadband mid-infrared radiation sources,which unify the properties of high brightness and spatial and temporal coherence.Due to the lack of such radiation sources,several emerging applications can be addressed only with infrared(IR)-beamlines in largescale synchrotron facilities,which are limited regarding user access and only partially fulfill these properties.Here,we present a table-top,broadband,coherent mid-infrared light source that provides brightness at an unprecedented level that supersedes that of synchrotrons in the wavelength range between 3.7 and 18μm by several orders of magnitude.This result is enabled by a high-power,few-cycle Tm-doped fiber laser system,which is employed as a pump at 1.9μm wavelength for intrapulse difference frequency generation(IPDFG).IPDFG intrinsically ensures the formation of carrierenvelope-phase stable pulses,which provide ideal prerequisites for state-of-the-art spectroscopy and microscopy. | Christian Gaida Martin Gebhardt Tobias Heuermann Fabian Stutzki Cesar Jauregui Jose Antonio-Lopez Axel Schulzgen Rodrigo Amezcua-Correa Andreas Tunnermann Ioachim Pupeza Jens Limpert | 2018 | Light(Science & Applications)2018，7，1： | 8 |
| 3 | E-cadherin adhesion molecule and syndecan-1 expression in various thyroid pathologies 显示文摘 | Mitselou A Ioachim E Peschos D | 2007 | Exp Onco12007，29，1： | 1 |
| 4 | hnmunohistochemical study of extracellular matrix com- ponents in epiretinal membranes of vitreoprolfferative retinopa- thy and proliferative diabetic retinopathy 显示文摘 | Ioachim E Stefaniotou M Gorezis S Tsanou E Psilas K Agnan- tis NJ | 2005 | Eur J Ophthal- tool2005，15，3： | 1 |
| 5 | Fleet assignment and routing with schedule synchronization constraints 显示文摘 | I Ioachim J Desrosiers F Soumis | 1999 | European Journal of Operational Research1999，119，1： | 1 |
| 6 | lmmunohistochemical study of extracellular matrix components in epiretinal membranes of vitreoproliferative retinopathy and proliferative diabetic retinopathy 显示文摘 | Ioachim E Stefaniotou M Gorezis S | 2005 | Eur J Ophthalmol2005，15，3： | 1 |
| 7 | Glycoprotein CD44 expression in benign, prema- lignant and malignant epithelial lesions of the larynx: an immunohistochemical study including correlation with Rb, p53, ki-67 and PCNA 显示文摘 | IOACHIM E ASSIMAK O D GOUSSIA A C | 1999 | Histol Histopathol1999，14，： | 1 |
| 8 | Thrombospondin-1 expression in breast cancer:prognostic significance and association with p53 alterations,tumour angiogenesis and extracellular matrix components显示文摘 | Ioachim E Damala K Tsanou E | 2012 | Histol Histopathol2012，27，： | 1 |
| 9 | Prognostic evaluation of metallothionein expression in human colorectal neoplasms显示文摘 | Ioachim EE Goussia AC Agnantis NJ | 1999 | J Clin Pathol1999，52，12： | 1 |
| 10 | Expression of organic anion - transporting polypeptides 1B3,1 B1, and 1 A2 in human pancreatic cancer reveals a new class of potential therapeutic targets显示文摘 | Kounnis V Ioachim E Svoboda M | 2011 | Once Targets Ther2011，4，： | 1 |
| 11 | Clinicopathological study of the expression of hsp27 , ps2, cathepsin D and metallothionein in primary invasive breast cancer 显示文摘 | Ioachim E Taanou E Briasoulis E | 2003 | Breast2003，12，2： | 1 |
| 12 | Clinicopathological study of the expression of hsp27, pS2, cathepsin D and metal othionein in primary invasive breast cancer显示文摘 | Ioachim E Tsanou E Briasoulis E | 2003 | Breast2003，12，2： | 1 |
| 13 | Matrix metalloproteinase expression in human breast cancer: an immunohistochemical study including correlation with cathepsin D, type Ⅳ collagen, laminin, fibronectin, EGFR, c-erbB-2, P53, steroid receptors status and proliferative indices显示文摘 | Ioachim EE Athanassiadou SE Kamina S | 1998 | Anticancer Res1998，18，： | 1 |
| 14 | Immunohistochemical expression of cathepsin D in correlation with extracellular matrix component,steroid receptor status and proliferative indices in breast cancer显示文摘 | Ioachim E Kamina S Kontostolis M | 1997 | Virchows Arch1997，431，5： | 1 |
| 15 | Immunohistochemical expression of extracellular matrix components tenascin,fibronectin,collagen type Ⅳ and laminin in breast cancer:their prognostic value and role in tumour invasion and progression显示文摘 | IOACHIM E CHARCHANTI A BRIASOULIS E | 2002 | Eur J Cancer2002，38，18： | 1 |
| 16 | Immunohistochemical evaluation of cathepsin D expression in colorectal tumours:a correlation with extracellular matrix components,p53,pRb,bcl-2,c-erbB-2,EGFR and proliferation indices显示文摘 | Ioachim EE Goussia AC Machera M | 1999 | Anticancer Res1999，19，3： | 1 |
| 17 | Expression of the cell-cycle regulatory protein( cyclins D1 and E) in endometrial carcinomas:correlations with homone receptor status, proliferating indices, tumor suppressor gene products ( p53, pRb ) , and clinicopathological parameters显示文摘 | Mitselou A Ioachim E Zagorianakou N | 2004 | Eur J Gynaecol Oncol2004，25，6： | 1 |
| 18 | Ceramic materials Ba (1<ce:hsp sp='0.12'/>?<ce:hsp sp='0.12'/> x ) Sr x TiO 3 for electronics — Synthesis and characterization显示文摘 | C. Berbecaru H.V. Alexandru C. Porosnicu A. Velea A. Ioachim L. Nedelcu M. Toacsan | 2008 | Thin Solid Films2008，，22： | 1 |
| 19 | Expression pattems of cyclins D1, E and cyclin-dependent kinase inhibitors p21 and p27 in urothelial carcinoma : correlation with other cell-cycle-related proteins (Rb, 163, Ki-67 and PCNA) and clinicopathological features显示文摘 | Ioachim E Michael M Stavropoulos N E | 2004 | Urol Int2004，73，1： | 1 |
| 20 | Hypoxia-inducible factors HIF-1alpha and HIF-2alpha expression in bladder cancer and their associations with other angiogenesis-related proteins显示文摘 | Ioachim E Michael M Salams M | 2006 | Urol 1nt2006，77，3： | 1 |
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