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| 1 | Cytomegalovirus positive ulcerative colitis:A single center experience and literature review显示文摘AIM:To compare the clinical outcome of cytomegalovirus(CMV)-positive ulcerative colitis(UC) patients with and without antiviral therapy.METHODS:This was a retrospective case-controlled study.The database of UC patients in our institution was scanned for documented presence of CMV on colonic biopsies.Demographics,clinical data,endoscopy findings and pathology reports were extracted from the patients' charts and electronic records.When available,the data from colonoscopies preceding and following the diagnosis of colonic CMV infection were also ex-tracted.The primary outcomes of the study were colectomy/death during hospitalization and the secondary outcomes were colectomy/death through the course of the follow-up.RESULTS:Thirteen patients were included in the study,7(53.5%) of them were treated with gancyclovir and 6(46.5%) were not.Patients treated with antivirals presented with a more severe disease and 57% of them were treated with cyclosporine or infliximab before initiation of gancyclovir,while none of the patients without antivirals required rescue therapy.One patient died and another patient underwent urgent colectomy during hospitalization,both of them from the gancyclovir-treatment group.For the entire follow-up time(13 ± 13 mo),a total of 3 colectomies and one death occurred,all among the antiviral-treated patients(for colectomy:3/7 vs 0/6 patients,P = 0.19;for combined adverse outcome:4/7 vs 0/6 patients,P = 0.07).In 9/13 patients,immunohistochemistry for CMV was performed on biopsies obtained during a subsequent colonoscopy and was positive in one patient only.CONCLUSION:Gancyclovir-treated patients had a more severe disease and outcome,probably unrelated to antiviral therapy.Immunohistochemistry-CMV-positive patients with mild disease may recover without antiviral therapy. | Uri Kopylov Gila Sasson Bella Geyshis Michal Tepperberg Oikawa Iris Barshack Rami Eliakim Shomron Ben-Horin | 2013 | World Journal of Gastrointestinal Pathophysiology2013，4，1： | 10 |
| 2 | Structural basis for hyperpermeability of tumor vessels in advanced lung adenocarcinoma complicated with pleural effusion显示文摘 | Maya Damianovich Goni Hout Siloni Iris Barshack David A. Simansky Debora Kidron Erel Dar Camila Avivi Amir Onn | 2013 | Clinical Lung Cancer2013，，： | 1 |
| 3 | Transplantation of human bone marrow mesenchymal stem cells as a thin subretinal layer ameliorates retinal degeneration in a rat model of retinal dystrophy显示文摘 | Adi Tzameret Ifat Sher Michael Belkin Avraham J. Treves Amilia Meir Arnon Nagler Hani Levkovitch-Verbin Iris Barshack Mordechai Rosner Ygal Rotenstreich | 2014 | Experimental Eye Research2014，，： | 1 |
| 4 | Allicin inhibits spontaneous and TNF-α induced secretion of proinflammatory cytokines and chemokines from intestinal epithelial cells显示文摘 | Alon Lang Maor Lahav Emad Sakhnini Iris Barshack Herma H. Fidder Benjamin Avidan Eitan Bardan Rami Hershkoviz Simon Bar-Meir Yehuda Chowers | 2004 | Clinical Nutrition2004，，5： | 1 |
| 5 | Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice显示文摘 | Yehuda Kamari Aviv Shaish Einav Vax Shay Shemesh Michal Kandel-Kfir Yaron Arbel Sarita Olteanu Iris Barshack Shahar Dotan Elana Voronov Charles A. Dinarello Ron N. Apte Dror Harats | 2011 | Journal of Hepatology2011，，5： | 1 |
| 6 | Flare-up of ulcerative colitis after systemic corticosteroids: A strong case for Strongyloides显示文摘Super-imposed infection with intestinal organisms can mimic a flare-up of underlying disease in patients with inflammatory bowel disease (IBD). We report a case of patient with long standing ulcerative colitis (UC), who presented with abdominal pain, diarrhea and low- grade fever after receiving systemic corticosteroids for an unrelated disorder. Despite a negative stool examination, a peripheral eosinophilia reappeared upon tapering down of a corticosteroid dose. Subsequently, duodenal biopsies showed evidence for Strongyloides, presumably acquired 20 years ago when the patient was residing in Brazil. The patient fully recovered following anti-helmintic therapy. This case underscores the importance of considering Strongyloides in the work-up of flaring-up IBD patients, even if a history of residing or traveling to endemic areas is in the distant past. | Shomron Ben-Horin Iris Barshack Yehuda Chowers Meir Mouallem | 2008 | World Journal of Gastroenterology2008，14，27： | 1 |
| 7 | Erythropoietin improves myocardial performance in doxorubicin-induced cardiomyopathy显示文摘 | Saher Hamed Iris Barshack Galia Luboshits | 2006 | Eur Heart J2006，27，15： | 1 |
| 8 | Effect of beta blocker combined with COX-2 inhibitor on colonic anastomosis in rats显示文摘 | Barak Benjamin Ofir Hazut Lee Shaashua Marganit Benish Niv Zmora Iris Barshack Aviad Hoffman Shamgar Ben-Eliyahu Oded Zmora | 2010 | International Journal of Colorectal Disease2010，，12： | 1 |
| 9 | Erythropoietin improves myocardial performance in doxorubicin-induced eardiomyopathy 显示文摘 | Hamed Saher Barshack Iris Luboshits Galia | 2006 | Eur Heart J2006，27，15： | 1 |
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