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| 1 | Outcome of patients with acute, necrotizing pancreatitis requiring drainage-does drainage size matter?显示文摘AIM:To assess the outcome of patients with acute necrotizing pancreatitis treated by percutaneous drainage with special focus on the influence of drainage size and number. METHODS:We performed a retrospective analysis of 80 patients with acute pancreatitis requiring percutaneous drainage therapy for infected necroses. Endpoints were mortality and length of hospital stay. The influence of drainage characteristics such as the median drainage size, the largest drainage size per patient and the total drainage plane per patient on patient outcome was evaluated. RESULTS:Total hospital survival was 66%. Thirty-four patients out of all 80 patients (43%) survived acute necrotizing pancreatitis with percutaneous drainage therapy only. Eighteen patients out of all 80 patients needed additional percutaneous necrosectomy (23%). Ten out of these patients required surgical necrosectomy in addition, 6 patients received open necrosectomy without prior percutaneous necrosectomy. Elective surgery was performed in 3 patients receiving cholecystectomy and one patient receiving resection of the parathyroid gland. The number of drainages ranged from one to fourteen per patient. The drainage diameter ranged from 8 French catheters to 24 French catheters. The median drainage size as well as the largest drainage size used per patient and the total drainage area used per patient did not show statistically significant influence on mortality. CONCLUSION:Percutaneous drainage therapy is an effective tool for treatment of necrotizing pancreatitis.Large bore drainages did not prove to be more effective in controlling the septic focus. | T Bruennler J Langgartner S Lang CE Wrede F Klebl S Zierhut S Siebig F Mandraka F Rockmann B Salzberger S Feuerbach J Schoelmerich OW Hamer | 2008 | World Journal of Gastroenterology2008，14，5： | 23 |
| 2 | Significance of scintigraphy for the localisation of obscure gastrointestinal bleedings显示文摘AIM: To determine the role of scintigraphy in patients with gastrointestinal (GI) bleeding of unknown localisation. METHODS: We performed retrospective analyses on 92 patients receiving scintigraphies from 1993 to 2000 in the University of Regensburg hospital, which were done for localisation of GI bleeding as a diagnostic step after an unsuccessful endoscopy. In addition to the scintigraphies, further diagnostic steps such as endoscopy, angiography or operations were performed. In some of the scintigraphies with negative results, a provocation test for bleeding with heparinisation was carried out. RESULTS: 73% of all scintigraphies showed a positive result. In 4.5% of the positive results, the source was located in the stomach, in 37% the source was the small bowel, in 25% the source was the right colon, in 4.5% the source was the left colon, and in 20% no clear localisation was possible. Only 4% of all scintigraphies were false positive. A reliablepositive scintigraphy was independent of the age of the examined patient. A provocation test for bleeding with heparin resulted in an additional 46% of positive scintigraphies with a reliable localisation in primary negative scintigraphies. CONCLUSION: Our results show that scintigraphy and scintigraphy with heparin provocation tests are reliable procedures. They enable a reliable localisation in about half of the obscure GI-bleeding cases. Scintigraphy is superior to angiography in locating a bleeding. It is shown that even in the age of video capsule endoscopy and double-balloon enteroscopy, scintigraphy provides a reliable and directed localization of GI bleeding and offers carefully targeted guidance for other procedures. | Tanja Brünnler Frank Klebl Sascha Mundorff Christoph Eilles Michael Reng Hans von Korn Jürgen Schlmerich Julia Langgartner Stefan Grüne | 2008 | World Journal of Gastroenterology2008，14，32： | 3 |
| 3 | Frequency and outcome of patients with nonthyroidal illness syndrome in a medical intensive care unit 显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
| 4 | Comparison of the pharmacokinetics of piperacillin and sulbactam during in-termittent and continuous intravenous infusion显示文摘 | Langgartner J Lehn N Gluck T | 2007 | Chemo-therapy2007，53，： | 1 |
| 5 | Frequency and outcome of patients with nonthyroidal illness syndrome in a medical intensive care unit 显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
| 6 | Frequency and outcome of patients with nonthyroidal illness syndrome in a medical intensive care unit 显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
| 7 | Combined skin disinfection with chlorhexidine/propanol and aqueous povidone-iodine reduces bacterial colonisation of central venous catheters显示文摘 | Langgartner J Linde HJ Lehn N | 2004 | Intensive Care Med2004，30，6： | 1 |
| 8 | Frequency and outcome of patients with nonthyroidal illness syndrome in a medical intensive care unit 显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
| 9 | Frequency and outcome of patients with nonthyroidal illness syndrome in a medical intensive care unit显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
| 10 | Fre- quency and outcome of patients with nonthyroidal illness syndrome in a medical intensive care unit显示文摘 | PLIKAT K LANGGARTNER J BUETI'NER R | 2007 | Metabolism2007，56，2： | 1 |
| 11 | Combined skin disinfection with c - hlorhexidine/propanol and aqueous povidone - iodine reduces bacterial colonisat - ion of central venous catheters显示文摘 | Langgartner J Linde HJ Reng M | 2004 | Intensive Care Med2004，30，6： | 1 |
| 12 | Frequency and outcome of patients with nonthyroidal illness syndrome in a medical inten- sive care unit 显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
| 13 | Frequency and outcome of patients with nonthyroidal illness syndrome in a medical inten- sive care unit 显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
| 14 | Comparison of the pharmacokinetics of piperacillin and sulbactam during intermittent and continuous intravenous infusion 显示文摘 | Langgartner J Lehn N Gltiek T | 2007 | Chemotherapy2007，53，5： | 1 |
| 15 | Frequencyand outcome of patients with nonthyroidal illness syn-drome in a medical intensive care unit显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
| 16 | Frequency and outcome of patients with nonthyroidal illness syndrome in a medical intensive care unit 显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
| 17 | Dengue Virus Infection Transmitted by Needle Stick Injury显示文摘 | Langgartner J Audebert F Scholmerich J | 2002 | J Infect2002，44，4： | 1 |
| 18 | Pharmacokinetics of meropenem during intermittent and continuous intravenous application in patients treated by continuous renal replacement therapy显示文摘 | LANGGARTNER J VASOLD A GLOCK T | 2008 | Intens Care Med2008，34，6： | 1 |
| 19 | Frequency and outcome of patients with nonthyroidal illness syndrome in a medical intensive care unit显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
| 20 | Frequency and out- come of patients with nonthyroidal illness syndrome in amedical in- tensive care unit显示文摘 | Plikat K Langgartner J Buettner R | 2007 | Metabolism2007，56，2： | 1 |
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