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| 1 | 老年糖尿病病人心脏病的治疗问题显示文摘许多实验室和临床研究指出老化和糖尿病过程可能引起心脏功能及其结构的改变。这些改变与心肌缺血无关。上述两种情况伴有间质胶原的积聚使左室舒张期顺应性降低,并有心室弛缓率降低。在亚临床状态时,衰老的心肌细胞增大,但在糖尿病时并无此种情况描述。在亚临床状态病人中一部分可进展为收缩期功能异常、心力衰竭和心律失常。但尚无确切证据说明两种状态下弥散性心肌病变是由于心壁内小血管病造成的。治疗上需要特别注意强心剂的应用。 | Regan T J 王桂珍 杨德发 | 1990 | 国外医学(老年医学分册)1990，11，3： | 7 |
| 2 | Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review显示文摘Human papillomavirus(HPV) has been implicated in the pathogenesis of a subset of oropharyngeal squamous cell carcinoma. As a result, traditional paradigms in relation to the management of head and neck squamous cell carcinoma have been changing. Research into HPVrelated oropharyngeal squamous cell carcinoma is rapidly expanding, however many molecular pathological and clinical aspects of the role of HPV remain uncertain and are the subject of ongoing investigation. A detailed search of the literature pertaining to HPV-related oropharyngeal squamous cell carcinoma was performed and information on the topic was gathered. In this article, we present an extensive review of the current literature on the role of HPV in oropharyngeal squamous cell carcinoma, particularly in relation to epidemiology, risk factors, carcinogenesis, biomarkers and clinicalimplications. HPV has been established as a causative agent in oropharyngeal squamous cell carcinoma and biologically active HPV can act as a prognosticator with better overall survival than HPV-negative tumours. A distinct group of younger patients with limited tobacco and alcohol exposure have emerged as characteristic of this HPV-related subset of squamous cell carcinoma of the head and neck. However, the exact molecular mechanisms of carcinogenesis are not completely understood and further studies are needed to assist development of optimal prevention and treatment modalities. | Robbie SR Woods Esther M O'Regan Susan Kennedy Cara Martin John J O'Leary Conrad Timon | 2014 | World Journal of Clinical Cases2014，2，6： | 5 |
| 3 | 澳大利亚人乳头状瘤病毒疫苗计划实施5年对年轻人群生殖器疣患病情况的影响:国家调查数据分析显示文摘目的评估2007年中开始的澳大利亚人乳头状瘤病毒(HPV)疫苗计划对生殖器疣患病情况的影响。设计国家调查数据趋势分析。数据来源数据收集于2004--2011年度澳大利亚8所性健康服务机构;其中2所最大的临床中心收集了自我报告的本中心2009年度HPV疫苗现状。研究对象2004--2011年度首次就诊的85770名澳大利亚出生的国民;其中7686(9.0%)名患生殖器疣。主要结局测量比较前疫苗时期(2004—2007年中)和疫苗时期(2007年中-2001年末)不同人群生殖器疣新发病率变化趋势。结果疫苗时期21岁以下和21~30岁女性诊断患有生殖器疣的比例明显下降,发病率分别从2007年度的11.5%和11.3%下降至2011年度的0.85%和3.1%,P均〈0.001。在30岁以上的女性中未发现发病率的明显下降。在21岁以下和21~30岁异性恋男性人群中疫苗时期生殖器疣的发病率较前疫苗时期明显下降,分别由2007年度12.1%和18.2%下降至2011年度2.2%和8.9%,P均〈0.001。30岁以上的异性恋男性人群中发病率无明显下降。2011年235名21岁以下女性在使用HPV疫苗后无新发生殖器疣病例。结论年轻女性生殖器疣发病率的显著下降和2011年度部分年轻女性使用疫苗后的零发病率,说明HPV疫苗获得实验室外的良好功效。异性恋男性生殖器疣发病率的显著下降可能是由于群体免疫所致。 | Hammad Ali,lecturer Basil Donovan, professor HandanWand,senior lecturer Tim R H Read, sexual health physician David G Regan,senior lecturer Andrew E Grulich, professor Christopher K FaMey, professor Rebecca J Guy, associate professor 尹婕(译) 潘凌亚(校) | 2013 | 英国医学杂志中文版2013，16，4： | 4 |
| 4 | 综合老化腐蚀试验显示文摘介绍了综合老化腐蚀试验,包括其循环试验条件、腐蚀试验结果验证及试验方法的改进,指出该方法是检验工业防护涂层实用性的最有效试验方法之一。 | J Quill J Gauntner S Fowler J Regan 张恒 孙杏蕾 | 2015 | 上海涂料2015，53，5： | 3 |
| 5 | Advanced oxidation processes for treating groundwater contaminated with TCE and PCE:pilot scale evaluations显示文摘 | Aieta E M Regan K M Lang J S | 1998 | AWWA1998，80，： | 1 |
| 6 | Percutaneous nephrostomy with extensions of the technique: step by step 显示文摘 | DYER R B REGAN J D KAVANAGH P V | 2002 | Radiographics2002，22，： | 1 |
| 7 | Ultrasonic endoscope显示文摘 | DiMagno E P Buxton J L Regan P T Hattery R R Wilson D A Suarez J R | 1980 | Lancet1980，1，： | 1 |
| 8 | Simvastatin reduces human atrial myofibroblast proliferation independently of cholesterol lowering via inhibition of RhoA显示文摘 | Porter K E Turner N A O'Regan D J | 2004 | Cardiovasc Res2004，61，4： | 1 |
| 9 | Evolutionary relationships among ammonia-and nitrite-oxidizing bacteria 显示文摘 | Teske A Aim E Regan J M | 1994 | Journal of Bacteriology1994，176，21： | 1 |
| 10 | Approximation algorithms for the bid construction problem in combinatorial auctions for the procurement offreight transportation contracts显示文摘 | Song J Regan A | 2005 | Transportation Research: Part B2005，39，10： | 1 |
| 11 | 查看详情显示文摘 | Regan S P Marozas J A Craxton R S Kelly J H Donaldson W R Jaanimagi P A Jacobs-Perkins D Keck R L Kessler T J Mey-erhofer D D Sangster T C Seka W Smalyuk V A Sknpsky S Zuegel J D | | 0，，： | 1 |
| 12 | Analysis of ammonia loss mechanisms in microbial fuel cells treating animal wastewater显示文摘 | Kim J R Yi Z Regan J M | 2008 | Biotechnology&Bioengineering2008，99，5： | 1 |
| 13 | Driver distraction: The effects of concurrent in-vehicle tasks, road environment complexity and age on driving performance显示文摘 | HORBERRY T ANDERSON J REGAN M A | 2006 | Accident Analysis and Prevention2006，38，1： | 1 |
| 14 | Randomized phase Ⅲ trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma显示文摘 | McDermott D F Regan M Clark J I | 2005 | J Clini Oncol2005，23，1： | 1 |
| 15 | Analgesic effects of lowdoes ropivacaine for interscalene brachial plexus block for out-painent shoulder surgery-a dose-finding study显示文摘 | Krone SC Chan VW Regan J | 2001 | Beg Anesth Pain Med2001，26，5： | 1 |
| 16 | Electricity-preducing bacterial communities in microbial fuel cells 显示文摘 | Logan B E Regan J M | 2006 | Trends in Microbiology2006，14，： | 1 |
| 17 | Car-bonic anhydrase IX and pathological features as predic-tors of outcome in patients with metastatic clear-cell re-nal cell carcinoma receiving vascular endothelial growthfactor-targeted therapy显示文摘 | Choueiri T K Regan M M Rosenberg J E | 2010 | BJU Int2010，106，6： | 1 |
| 18 | Selective use of peri-operative steroids in pituitary tumor surgery: escape from dogma 显示文摘 | Regan J Watson J | 2013 | Front Endocrinol (Lausanne)2013，4，： | 1 |
| 19 | Hydrogen and methane production from swine wastewater using microbial electrolysis cells 显示文摘 | Wagner R C Regan J M Oh S E | 2009 | Water Research2009，43，： | 1 |
| 20 | Heat stability and freeze-thaw stability of oil-in-water emulsions stabilized by sodium caseinate-maltodextrin conjugates显示文摘 | O'Regan J Mulvihill D M | 2010 | Food Chemistry2010，119，1： | 1 |
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