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| 1 | A new procedure to estimate the rainfall erosivity factor based on Tropical Rainfall Measuring Mission(TRMM) data显示文摘Soil erosion by water is the most important land degradation problem worldwide.In this paper a new procedure was developed to estimate the rainfall-runoff erosivity factor(R)based on Tropical Rainfall Measuring Mission(TRMM)satellite-estimated precipitation data,which consists of 3-h rainfall intensity data.In this method,R was calculated as the product of the maximum 180-min rainfall intensity and the rainfall energy.This procedure was applied to the Daling River basin in Liaoning Province,China,R in terms of yearly,monthly and event-based rainfall in 2005 was computed separately using TRMM 3B42 data.The TRMM data showed a significant correlation with the interpolated rain-gauge data.Furthermore,because the TRMM data are based on rainfall intensity,they can represent the impact on erosion more accurately.It reflects both the spatial distribution and the intensity of rainfall.The procedure is a new approach to estimate the rainfall erosivity for soil water erosion modeling,especially in areas lacking rain-gauge stations. | ZHU Qiang CHEN XiuWan FAN QiXiang JIN HePing LI JiRen | 2011 | Science China(Technological Sciences)2011，54，9： | 15 |
| 2 | The expression of glucose regulated protein-94 in colorectal carcinoma cells treated by sodium butyrate显示文摘The expression of glucose regulated protein 94 (GRP94)during the treatment of human colorectal carcinoma cell lineClone A cells with sodium butyrate was studied. Sodium butyrate (SB) can cause functional and morphological effects on Clone A cells including growth arrest at Go/G1 stage and cell differentiation as observed by morphological changes, MTT and flow cytometry assays, as well as reduced Grp94 gene expression as shown by Northern blot and Western blot assays. The possible mechanism of the correlation between Grp94 gene expression and tumor growth inhibition and cell differentiation is briefly discussed. | WU YI DI JIN DAN SONG( Fax: (024)23256087 E-mail: jdsong@sun10.cmu.edu.cn)(Key Laboratory of Cell Biology, Ministry of Public Health of ChinaInstitute of Medical Molecular Biology, China Medical University, 92 Beier Rd. Heping District, Shenyang 110001, | 2000 | Cell Research2000，10，2： | 9 |
| 3 | Secondary Austenite Morphologies in Fusion Zone of Welded Joint after Postweld Heat Treatment with a Continuous Wave Laser显示文摘In order to improve the weldability of duplex stainless steels,obtaining more secondary austenite in the weld metal is an effective way.Therefore,optimizing the secondary austenite by changing its morphology,volume fraction and stability may be expected to enhance the ductility of the weld.The secondary austenite morphologies in the fusion zone of the laser continuously heat treated welds of 2205 duplex stainless steel were investigated.The secondary austenite morphologies were found to be influenced by different laser power level.The secondary austenite with penniform,freely grown and dendritic shape appeared in the course of 4,6 and 8 kW continuous heat treatment,respectively.It was found that there were three kinds of morphologies of secondary austenite in the fusion zone treated by different power,i.e.,widmannst¨atten austenite,grain boundary austenite and intragranular austenite.The results demonstrated that the mechanism of the secondary austenite formation was a displacement mechanism during the initial austenite lath formation and a diffusion mechanism during cooling.The nitrides provided the nitrogen for the transformation and at the same time acted as nucleation sites for the secondary austenite. | Heping Liu Xuejun Jin | 2012 | Journal of Materials Science & Technology2012，28，3： | 6 |
| 4 | An ultrahigh strength steel produced through deformation-induced ferrite transformation and Q&P process显示文摘In this work,DIFT technology and Q&P process were combined in order to introduce ultrafine-grained ferrite into the matrix of martensite and retained austenite to develop a new kind of advanced high strength steel,and two kinds of steels were investigated by this novel combined process.The newly designed process resulted in a sophisticated microstructure of a large amount of ferrite(about 5 m in diameter),martensite and a considerable amount of retained austenite for TRIP 780 steel.The ultimate tensile strength can reach about 1200 MPa with elongation above 16% for TRIP 780,that is much higher than the one solely treated by Q&P process.Tensile tests showed that both steels with the novel combined process achieved a good combination of strength and ductility,indicating that the new process is promising for the new generation of advanced high strength steels. | CHEN MingMing WU RiMing LIU HePing WANG Li SHI Jie DONG Han JIN XueJun | 2012 | Science China(Technological Sciences)2012，55，7： | 3 |
| 5 | Effect of adjuvant therapy with electroacupuncture on bone turnover markers and interleukin 17 in patients with rheumatoid arthritis显示文摘OBJECTIVE: To evaluate the effect of electroacupuncture as an adjuvant treatment with first-line medications on bone metabolism biomarkers and interleukin-17(IL-17) in the peripheral blood of patients with rheumatoid arthritis(RA).METHODS: Sixty RA patients were randomized into three groups. The control group was treated with methotrexate plus leflunomide(MTX + LEF),the acupuncture group was treated with simple needling plus MTX + LEF, and the patients in the electroacupuncture(EA) group were treated with EA plus MTX + LEF. EA or acupuncture was applied every other day for a total of 10 times over a treatment period of 8 weeks.RESULTS: In all three treatment groups, serum levels of the bone metabolism markers PICP, N-MID,and B-ALP were elevated and the concentrations of the inflammatory markers β-CTx, IL-17, CRP, and TRACP-5b were reduced after treatment. These differences were significant for the EA group but not the other groups(P < 0.05).CONCLUSION: EA could effectively reduce the suffering and improve the quality of life of RA patients. It is a promising adjuvant therapy for enhancing the effectiveness of clinical therapeutics. | Zeng Chuang Bai Xuejing Qin Heping Wang Hong Rong Xiaofeng Yan Jin | 2019 | Journal of Traditional Chinese Medicine2019，39，4： | 2 |
| 6 | Arabidopsis Synaptotagmin 2 Participates in Pollen Germination and Tube Growth and Is Delivered to Plasma Membrane via Conventional Secretion显示文摘Arabidopsis synaptotagmin (SYT2 ) 2 被报导了在体的房间参予一条异乎寻常的能分泌的小径。我们的结果证明 SYT2 主要在 Arabidopsis thaliana 的花粉被表示。展出的 syt2 T-DNA 和 RNA 干扰异种线的花粉减少了全部的萌芽并且阻碍了花粉试管生长。在 SYT2 对不同、补缀的分隔空间局部性,但是能与 Golgi 标记, BODIPY TR C5 ceramide 和 GmMan1-mCherry 共同本地化的花粉 tubeindicates 的 SYT2-GFP 熔化蛋白质的表示的分析。然而,对在 Arabidopsis 暂停房间的血浆膜局部性的 SYT2-DsRed-E5was,除了 Golgi 仪器。在血浆膜的 SYT2 的本地化被在花粉试管染色的 immunofluorescence 进一步支持。而且, brefeldin Atreatment 禁止了 SYT2 的运输到血浆膜并且引起了 SYT2 聚集并且形成扩大分隔空间。SYT2-C2AB 领域的截断也在 Golgi 仪器导致了 SYT2 的保留。phospholipid 有约束力的试金显示出的 invitro SYT2-C2AB 领域以一种钙依赖者方式绑在 phospholipid 膜。一起拿,我们的结果显示了那 SYT2 为花粉萌芽和花粉试管生长被要求,并且涉及常规 exocytosis。 | Hui Wang Shengcheng Han Wei Siao Chunqing Song Yun Xiang Xiaorong Wu Pengyu Cheng Hongjuan Li JAn Jasik Karol Micieta JAn Turna Boris Voigtt Frantisek Baluska Jin Liu Yingdian Wang Heping Zhao | 2015 | Molecular Plant2015，8，12： | 2 |
| 7 | Phase transformation and mechanical properties in laser continuous heat treatment welds 显示文摘 | Liu Heping Lu Xianwen Jin Xuejun | 2011 | Materials and Design2011，，32： | 1 |
| 8 | cGAS guards against chromosome endto-end fusions during mitosis and facilitates replicative senescence显示文摘As a sensor of cytosolic DNA, the role of cyclic GMP-AMP synthase (cGAS) in innate immune response is well established, yet how its functions in different biological conditions remain to be elucidated. Here, we identify cGAS as an essential regulator in inhibiting mitotic DNA double-strand break (DSB) repair and protecting short telomeres from end-to-end fusion independent of the canonical cGAS-STING pathway. cGAS associates with telomeric/subtelomeric DNA during mitosis when TRF1/TRF2/POT1 are deficient on telomeres. Depletion of cGAS leads to mitotic chromosome end-to-end fusions predominantly occurring between short telomeres. Mechanistically, cGAS interacts with CDK1 and positions them to chromosome ends. Thus, CDK1 inhibits mitotic non-homologous end joining (NHEJ) by blocking the recruitment of RNF8. cGAS-deficient human primary cells are defective in entering replicative senescence and display chromosome end-to-end fusions, genome instability and prolonged growth arrest. Altogether, cGAS safeguards genome stability by controlling mitotic DSB repair to inhibit mitotic chromosome end-to-end fusions, thus facilitating replicative senescence. | Xiaocui Li Xiaojuan Li Chen Xie Sihui Cai Mengqiu Li Heping Jin Shu Wu Jun Cui Haiying Liu Yong Zhao | 2022 | Protein & Cell2022，13，1： | 1 |
| 9 | Therapeutic potential of C1632 by inhibition of SARS-CoV-2 replication and viral-induced inflammation through upregulating let-7显示文摘Dear Editor,The COVID-19 pandemic caused by SARS-CoV-2 has led to acute respiratory distress syndrome(ARDS)with a high rate of death.An excessive inflammatory response,caused by virus infection,is associated with severe clinical manifestations that may lead to death of patients.1 Therefore,the blockage of virus replication and suppression of hyper-inflammatory response are beneficial for COVID-19 treatment.However,the drug targeting both virus and hyper-inflammation,as far as we know,is not available yet. | Chen Xie Yanlian Chen Dongling Luo Zhen Zhuang Heping Jin Haoxian Zhou Xiaocui Li Haijun Lin Xiaohui Zheng Jing Zhang Peihui Wang Jincun Zhao Yong Zhao Hui Huang | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 1 |
| 10 | Enhanced mechanical properties of a hot stamped advanced high-strength steel treated by quenching and partitioning process显示文摘 | Liu Heping Lu Xianwen Jin Xuejun | 2011 | Scripta Materialia2011，64，8： | 1 |
| 11 | Martensitic microstructural transformations from the hot stamping, quenching and partitioning process显示文摘 | Liu Heping Jin Xuejun Dong Han | 2011 | Materials Characterization2011，62，2： | 1 |
| 12 | Application of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)combined with magnetic resonance spectroscopy(MRS)in prostate cancer diagnosis显示文摘Objective The aim of the study was to investigate the application of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)combined with magnetic resonance spectroscopy(MRS)in prostate cancer diagnosis.Methods In the outpatient department of our hospital(Sichuan Cancer Hospital,Chengdu,China),60 patients diagnosed with prostate disease were selected randomly and included in a prostate cancer group,60 patients with benign prostatic hyperplasia were included in a proliferation group,and 60 healthy subjects were included in a control group,from January 2013 to January 2017.Using Siemens Avanto 1.5 T high-field superconducting MRI for DCE-MRI and MRS scans,after the MRS scan was completed,we used the workstation spectroscopy tab spectral analysis,and eventually obtained the crest lines of the prostate metabolites choline(Cho),creatine(Cr),citrate(Cit),and the values of Cho/Cit,and(Cho+Cr)/Cit.Results Participants who had undergone 21-s,1-min,and 2-min dynamic contrast-enhanced MR revealed significant variations among the three groups.The spectral analysis of the three groups revealed a significant variation as well.DCE-MRI and MRS combined had a sensitivity of 89.67%,specificity of 95.78%,and accuracy of 94.34%.Conclusion DCE-MRI combined with MRS is of great value in the diagnosis of prostate cancer. | Yakun He Min Wang Heping Deng Jin Ren | 2021 | Oncology and Translational Medicine2021，7，1： | 1 |
| 13 | Rare earth elements of aeolian deposits in Northern China and their implications for determining the provenance of dust storms in Beijing显示文摘 | Xiaoping Yang Yongsheng Liu Chaozhu Li Yuling Song Heping Zhu Xindi Jin | 2006 | Geomorphology2006，，4： | 1 |
| 14 | Design, Development and Implementation of Three Gorges Project Management System显示文摘This paper presents an analytic description of the background, general objective, design, development and implementation course of the Three Gorges Project Management System (TGPMS), puts forward a universal system structure of software management for a big scale project, and states some key factors for building a successful system through analysis of the course of building TGPMS. | Jin Heping (China Yangtze TGP Development Corporation, Yichang, Hubei\ 443002) | 2003 | 工程科学(英文版)2003，1，1： | 1 |
| 15 | Combustion synthesis of AlN–SiC solid solution particles显示文摘 | Chen Kexin Jin Haibo Zhou Heping José M.F. Ferreira | 2000 | Journal of the European Ceramic Society2000，，14： | 1 |
| 16 | Enhanced mechanical properties of a hot stamped advanced high-strength steel treated by quenching and partitioning process显示文摘 | Heping Liu Xianwen Lu Xuejun Jin Han Dong Jie Shi | 2010 | Scripta Materialia2010，，8： | 1 |
| 17 | Time-resolved characterization of laser-induced plasma from fresh potatoes显示文摘 | Wenqi Lei Vincent Motto-Ros Myriam Boueri Qianli Ma Dacheng Zhang Lijuan Zheng Heping Zeng Jin Yu | 2009 | Spectrochimica Acta Part B: Atomic Spectroscopy2009，，9： | 1 |
| 18 | Cardioprotection of salidroside from ischemia,/reperfusion injury by increasing N-acetylglucosamine linkage to cellular proteins 显示文摘 | WU Tiejin ZHOU Heping JIN Zhenxiao | 2009 | European Journal of pharmacology2009，613，13： | 1 |
| 19 | Martensitic micro?structural transformation from the hot stamping, quenching and partitioning process 显示文摘 | Liu Heping Jin Xuejun Dong Han | 2011 | Materials Characterization2011，62，2： | 1 |
| 20 | 1B50-1, a mAb Raised against Recurrent Tumor Cells, Targets Liver Tumor-Initiating Cells by Binding to the Calcium Channel α2δ1 Subunit显示文摘 | Wei Zhao Limin Wang Haibo Han Kemin Jin Na Lin Ting Guo Yangde Chen Heping Cheng Fengmin Lu Weigang Fang Yu Wang Baocai Xing Zhiqian Zhang | 2013 | Cancer Cell2013，，： | 1 |
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