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| 1 | New oral pharmacotherapeutic agents for venous thromboprophylaxis after total hip arthroplasty显示文摘Patients undergoing total hip arthroplasty(THA)are at high risk for developing venous thromboembolism and,therefore,require short term prophylaxis with antithrombotic agents.Recently,target specific oral anticoagulants(TSOA)including the direct thrombin inhibitor,dabigatran,and the factorⅩa inhibitors rivaroxaban,apixaban,and edoxaban have been approved for THA thrombopropylaxis in various countries.The TSOAs provide a rapid acting,oral alternative to parenteral agents including low-molecular weight heparins(LMWH)and fondaparinux;and compared to warfarin,they do not require routine laboratory monitoring and possess much fewer drug-drug interactions.Based on phaseⅢclinical studies,TSOAs have established themselvesas an effective and safe option for thromboprophylaxis after THA compared to LMWH,particularly enoxaparin,but require additional evaluation in specific populations such as the renally impaired or elderly.The ability to monitor and reverse these TSOAs in the case of bleeding complications or suspected sub-or supra-therapeutic anticoagulation is of importance,but remains investigational.This review will focus on the drug-specific characteristics,efficacy,safety,and economic impact of the TSOAs for thromboprophylaxis following THA,as well as the aspects of therapeutic monitoring and anticoagulation reversal in the event of bleeding complications or a need for urgent reversal. | Garrett B Aikens Jacob R Osmundson Michael P Rivey | 2014 | World Journal of Orthopedics2014，5，3： | 3 |
| 2 | Efficient hydrolytic hydrogenation of cellulose in the presence of Ru-loaded zeolites and trace amounts of mineral acid显示文摘 | GEBOERS J VAN DE VYVER S CARPENTIER K JACOBS P SELS B | 2011 | Catal Commun2011，47，19： | 1 |
| 3 | A genomewide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer显示文摘 | HUNTER D J KRAFT P JACOBS K B | 2007 | Nature genetics2007，39，7： | 1 |
| 4 | GFAP and SIOOB are biomarkers of traumatic brain injury: an observa- tional cohort study显示文摘 | Vos P E Jacobs B Andriessen T M | 2010 | Neurology2010，75，20： | 1 |
| 5 | The formation of patterns in non-equilibrium growth显示文摘 | Jacob B Garik P | 1990 | Nature1990，343，： | 1 |
| 6 | 查看详情显示文摘 | Van de Vyver S Thomas J Geboers J Keyzer S Smet M Dehaen W Jacobs P A Sels B F | | 0，，09： | 1 |
| 7 | Randomised phase II study of cisplatin and 5-fluorouracil (5-FU) versus cisplatin alone in advanced squamous cell oesophageal cancer显示文摘 | H Bleiberg T Conroy B Paillot A.J Lacave G Blijham J.H Jacob L Bedenne M Namer P De Besi F Gay L Collette T Sahmoud | 1997 | European Journal of Cancer1997，，8： | 1 |
| 8 | Two-component waterborne polyurethane coating显示文摘 | Jacobs P B YU P C | 1993 | Journal of Coatings Technology1993，65，822： | 1 |
| 9 | GFAP and S100B are biomarkers of traumatic brain injury:an observational cohort study显示文摘 | Vos P E Jacobs B Andriessen TM | | 0，，20： | 1 |
| 10 | Sedimentary ag-gregates in the Peoria Loess of Nebraska,USA显示文摘 | Mason J A Jacobs P M Greene R S B | 2003 | Catena2003，57，： | 1 |
| 11 | Ginkgo biloba: A living fossil显示文摘 | Jacobs B P Browner W S | 2000 | Am J Med2000，108，： | 1 |
| 12 | Ginkgo biloba : a living fossil 显示文摘 | Jacobs B P Browner W S | 2000 | The A- merican Journal of Medicine2000，108，4： | 1 |
| 13 | Suprapubic catheter insertion using an ultrasound-guided technique and literature review显示文摘 | Jacob P Rai B P Todd A W | | 0，，06： | 1 |
| 14 | Genome sequence and analysis of the tuber crop potato显示文摘 | Xu X Pan S Cheng S Zhang B Mu D Ni P Zhang G Yang S Li R Wang J Orjeda G Guzman F Tones M Lnzano R Ponce O Martinez D De la Cruz G Chakrabarti S K Patil V U Skryabin K G Kuznetsov B B Ravin N V Kolganova T V Beletsky A V Mardanov A V Di Genova A Bolser D M Martin D M Li G Yang Y Kuang H Hu Q Xiong X Bishop G J Sagredo B Mejia N Zagorski W Gromadka R Gawor J Szczesny P Huang S Zhang Z Liang C He J Li Y He Y Xu J Zhang Y Xie B Du Y Qu D Bonierbale M Ghislain M Herrera Mdel R Giuliano G Pietrella M Perrotta G Faeella P O 'Brien K Feingold S E Barreiro L E Massa G A Diambra L Whitty B R Vaillancourt B Lin H Massa A N Geoffroy M Lundback S DellaPenna D Buell C R Sharma S K Marshall D F Waugh R Bryan G J Destefanis M Nagy I Milbourne D Thomson S J Fiefs M Jacobs J M Nielsen K L Sonderkaer M Iovene M Tortes G A Jiang J Veilleux R E Bachem C W de Boer J Bonn T Kloosterman B van Eck H Datema E Hekkert B Goverse A van Ham R C Visser R G | 2011 | Nature2011，475，7355： | 1 |
| 15 | The development of a tool to assess quality of cost estimates显示文摘 | Jacobs P Finlayson G Faienza B | 2002 | Disease Management&Health Outcomes2002，10，2： | 1 |
| 16 | Smoking, HIV and non-fatal tuberculosis in an urban African population显示文摘 | Ramin B Kam D Feleke B Jacob B Jha P | 2008 | Int Tuber Lung Dis2008，12，6： | 1 |
| 17 | Recent advances in the catalytic conversion of cellulose显示文摘 | VAN DE VYVER S GEBOERS J JACOBS P A SELS B F | 2011 | ChemCatChem2011，3，1： | 1 |
| 18 | Comparison of techniques for decompressive lumbar laminecto my:the minimally invasive versus the 'classic' open approach 显示文摘 | Rahman M Summers L E Richter B Mimran R I Jacob R P | 2008 | Minim Invasive Neurosurg2008，51，： | 1 |
| 19 | First world-wide interlaboratory study on polybrominated diphenyl ethers(PBDE) 显示文摘 | Jacob D B Wim P | 2002 | Chemosphere2002，46，： | 1 |
| 20 | Proce- dures for strain based assessment of pipeline dents 显示文摘 | Noronba D B Martins R R Jacob B P | 2010 | International Journal of Pressure Vessels and Piping2010，87，5： | 1 |
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