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| 1 | Clinical analysis of propofol deep sedation for 1,104 patients undergoing gastrointestinal endoscopic procedures:A three year prospective study显示文摘瞄准:在经历 gastros 拷贝和结肠镜检查的病人上分析 propofol 的血液动力学、呼吸的效果。方法:在这未来的研究,在三年的一个时期上进行了, 1,104 个病人参考了一一样的天官方补给的内视镜检查法过程被分析。所有病人被给一丸 propofol 大丸药(0.5-1.5 mg/kg ) 。动脉的血压(BP ) 在 3 min 间隔和心搏率被监视,氧饱和(SpO2 ) 被脉搏血氧定量法连续地记录。分析数据获得以前被执行,在期间,并且在过程以后。结果:在吝啬的动脉压的统计上重要的减小被表明(P <
0.001 ) 什么时候与干预前价值,而是严重低血压相比,在 60 毫米汞柱下面定义为收缩血压,在仅仅 5 个病人(0.5%) 被注意。氧饱和从 96.5% ~ 94.4 % 减少了(P <
0.001 ) 。在氧饱和的批评减少(<
90%) 在 27 个病人(2.4%) 被记录。结论:如果小心地滴定,我们的结果证明 propofol 向好镇静提供了优秀疼痛控制,短复原时间和没有重要血液动力学的副作用。所有病人(并且特别 ASA III 组) 要求监视并且一个麻醉学者关心。 | Stojanka Gaparovi Nadan Rustemovi Milorad Opai Marina Premuzi Andelko Korui Jadranka Bozikov Tamara Bates | 2006 | World Journal of Gastroenterology2006，12，2： | 41 |
| 2 | Role of Ki-67 as a prognostic factor in gastrointestinal stromal tumors显示文摘AIM:To investigate primarily the prognostic value of Ki-67,as well as other parameters,in gastrointestinal stromal tumors(GISTs).METHODS:Ki-67,c-KIT,platelet-derived growth factor receptor-alpha(PDGFRα),smooth muscle actin(SMA),CD34,S100 were stained for immunohistochemistry which was performed on formalin-fixed,paraffinembeded sections on representative block from each case.Proliferation index counted by Ki-67 antibody was calculated as a number of positive nuclear reaction over 100 cells.Immunoreactivity for c-KIT and PDGFRα was evaluated semiquantitatively(weak,intermediate,strong) and for c-KIT type of reactivity was analyzed(cytoplasmic,membrane and 'dot-like' staining).Immunoreactivity for SMA,CD34 and S100 were was evaluated as positive or negative antigen expression.Pathologic parameters investigated in this study included tumor size,cell type(pure spindle,pured epitheloid mixed spindle and epitheloid),mitotic count,hemorrhage,necrosis,mucosal ulceration.Clinical data included age,gender,primary tumor location and spread of disease.χ 2 test and Student's t-test were used for comparisons of baseline characteristics.The Cox's proportional hazard model was used for univariable and multivariable analyses.Survival rates were calculated by Kaplan-Meier method and statistical significance was determined by the log-rank test.RESULTS:According to the stage of disease,there were 36 patients with localized disease,29 patients with initially localized disease but with its recurrence in the period of follow up,and finally,35 patients had metastatic disease from the very beginning of disease.Tumor originated most commonly in the stomach(41%),small intestine was the second most common location(36%).The mean size of primary tumors was 6.5 cm.The mean duration of follow-up was 60 mo.Multiple parameters were analyzed for their effect on overall survival,but no one reached statistical significance(P = 0.06).Analysis of time to progression/relapse in initially localized disease(univariate analysis),tumor size,mitotic count,Ki-67 and type of d-KIT distribution(cytoplasmic vs membrane/'dot-like') showed statistically significant correlation.In multivariate analysis in the group of patients with localized disease,there were only 2 parameters that have impact on relapse,Ki-67 and SMA(P < 0.0001 and P < 0.034,respectively).Furthermore,Ki-67 was analyzed in localized diseasevs localized with recurrence and metastatic disease.It was shown that there is a strict difference between these 2 groups of patients(median value was 2.5 for localized disease vs 10.0 for recurrent/metastatic disease,P < 0.0001).It was also shown that the cut-off value which is still statistically significant in terms of relapse on the level of 6%.The curves for survival on that cut-off level are significantly different(P < 0.04,Cox F).CONCLUSION:Ki-67 presents a significant prognostic factor for GIST recurrence which could be of great importance in evaluating malignant potential of disease. | Borislav Belev Iva Bri Juraj Prejac Zrna Antunac Golubi Damir Vrbanec Jadranka Bozikov Ivan Aleri Marko Boban Jasminka Jaki Razumovi | 2013 | World Journal of Gastroenterology2013，19，4： | 14 |
| 3 | Pre-and intraoperative predictors of acute kidney injury after liver transplantation显示文摘BACKGROUND Acute kidney injury(AKI)after liver transplantation(LT)is a frequent and multifactorial event related to increased morbidity and mortality.Risk factors for AKI after LT still need to be clarified.AIM To identify the predictors of acute kidney injury after liver transplantation.METHODS The frequency and pre-and intraoperative predictors of AKI within the first 7 d after LT were evaluated in adult liver transplant candidates in a single LT center in Croatia.AKI was defined according to the Kidney Disease:Improving Global Outcomes criteria.RESULTS Out of 205 patients(mean age 57±10 years;73.7%males,52.7%with alcoholrelated liver disease)93(45.36%)developed AKI,and the majority of them(58.06%)had stage 1.Only 5.38%of patients required renal replacement therapy after LT.The majority of patients(82.8%)developed AKI within the first two days after the procedure.Multivariate logistic regression identified pre-LT body mass index(OR=1.1,95%CI:1.05-1.24)and red blood cell transfusion(OR=1.66,95%CI:1.09-2.53)as independent predictors of early post-LT AKI occurrence.30-d survival after LT was significantly better for patients without AKI(P=0.01).CONCLUSION Early AKI after LT is a frequent event that negatively impacts short-term survival.The pathogenesis of AKI is multifactorial,but pre-LT BMI and intraoperative volume shifts are major contributors. | Anna Mrzljak Lucija Franusic Jadranka Pavicic-Saric Tomislav Kelava Zeljka Jurekovic Branislav Kocman Danko Mikulic Ivan Budimir-Bekan Mladen Knotek | 2020 | World Journal of Clinical Cases2020，8，18： | 4 |
| 4 | Is Helicobacter pylori infection a risk factor for disease severity in systemic sclerosis?显示文摘 | Mislav Radi? Du?anka Martinovi? Kaliterna Damir Bonacin Jadranka Morovi? Vergles Josipa Radi? Damir Fabijani? Vedran Kova?i? | 2013 | Rheumatology International2013，，11： | 3 |
| 5 | BOWL-SHAPED POLY(3,4-ETHYLENEDIOXYTHIOPHENE)/γ-Fe_2O_3 COMPOSITES WITH ELECROMAGNETIC FUNCTION显示文摘In this paper, electromagnetic poly(3,4-ethylenedioxythiophene)/γ-Fe2O3 (PEDOT/γ-Fe2O3 ) micro-bowls, 1 2 μm in diameter, were prepared by a simple environment-friendly process. In this method, the aqueous solution of cetyltrimethylammonium bromide (CTAB) instead of any organic solvent was used. FeCl3 acted as a source of Fe Ⅲ for the formation of γ-Fe2O3 and as an oxidant for the polymerization of 3,4-ethylenedioxythiophene (EDOT). The bowl-shaped morphology of PEDOT/γ-Fe2O3 composites was strongly influenced by the concentration of CTAB, FeCl2 , ammonia solution and the reaction temperature. The saturation magnetization of PEDOT/γ-Fe2O3 micro-bowls increased with the increase of FeCl2 concentration and reached 6.20 Am2 /kg at the FeCl2 concentration of 0.30 mol/L. The conductivity of the PEDOT/γ-Fe2O3 composites was in the range of 101 S/cm. The electrical and magnetic sources of PEDOT/γ-Fe2O3 micro-bowls were confirmed by SEM-EDX, TEM, XRD and XPS spectra. And the possible formation mechanism of PEDOT//γ-Fe2O3 was proposed. | 张志明 Yue Wang Qiong Li Liang-min Yu Jadranka Travas-Sejdic Li-juan Zhang | 2013 | Chinese Journal of Polymer Science2013，31，3： | 2 |
| 6 | Emerging and neglected zoonoses in transplant population显示文摘Zoonoses represent a problem of rising importance in the transplant population.A close relationship and changes between human,animal and environmental health(“One Health”concept)significantly influence the transmission and distribution of zoonotic diseases.The aim of this manuscript is to perform a narrative review of the published literature on emerging and neglected zoonoses in the transplant population.Many reports on donor-derived or naturally acquired(re-)emerging arboviral infections such as dengue,chikungunya,West Nile,tick-borne encephalitis and Zika virus infection have demonstrated atypical or more complicated clinical course in immunocompromised hosts.Hepatitis E virus has emerged as a serious problem after solid organ transplantation(SOT),leading to diverse extrahepatic manifestations and chronic hepatitis with unfavorable outcomes.Some neglected pathogens such as lymphocytic choriomeningitis virus can cause severe infection with multi-organ failure and high mortality.In addition,ehrlichiosis may be more severe with higher casefatality rates in SOT recipients.Some unusual or severe presentations of borreliosis,anaplasmosis and rickettsioses were also reported among transplant patients.Moreover,toxoplasmosis as infectious complication is a well-recognized zoonosis in this population.Although rabies transmission through SOT transplantation has rarely been reported,it has become a notable problem in some countries.Since the spreading trends of zoonoses are likely to continue,the awareness,recognition and treatment of zoonotic infections among transplant professionals should be imperative. | Anna Mrzljak Rafaela Novak Nenad Pandak Irena Tabain Lucija Franusic Ljubo Barbic Maja Bogdanic Vladimir Savic Danko Mikulic Jadranka Pavicic-Saric Vladimir Stevanovic Tatjana Vilibic-Cavlek | 2020 | World Journal of Transplantation2020，10，3： | 2 |
| 7 | 十五肽BPC157减弱慢性苯丙胺诱导的行为障碍(英文)显示文摘AIM: To investigate the effect of pentadecapeptide BPC 157 on chronic exposure to amphetamine in rats, particularly the changes commonly referred in chronic amphetamine studies as tolerance ( lesser grade of stereotyped behavior, without increased excitability) and reverse tolerance (ie, prominent stereotyped behavior and heightened startle response upon late amphetamine challenges). METHODS: After initial application (initial single dose-regimen), amphetamine (10 mg/kg, ip) was given once daily till d 5 ( continuous administration-regimen), and thereafter on d 8, 16, and 46 (intermittent administration regimen). For stereotyped behavior and heightened startle response the observation period was 120 min after amphetamine application, and each animal was observed for 10 s in 5 min intervals. Pentadecapeptide BPC 157 (10 μg/kg or 10 ng/kg, ip) or saline (5.0 mL/kg, ip) were given only at the beginning of the experiment, simultaneously with the initial dose of amphetamine. RESULTS: In relation to | Predrag SIKIRIC, Nikola JELOVAC, Andjelka JELOVAC-GJELDUM, Goran DODIG, Mario STARESINIC, Tornislav ANIC, Ivan ZORICIC, Davor RAK, Darko PEROVIC, Gorana ARALICA, Gojko BULJAT, Ingrid PRKACEV, Martina LOVRIC-BENCIC, Jadranka SEPAROVIC, Sven SEIWERTH, Rudolf RUCMAN, Marijan PETEK, Branko TURKOVIC, Tihomil ZIGER, AJenka BOBAN-BLAGAIC, Vlado BEDEKOVIC, Ante TONKIC, Slaven BABIC ( Department of Pharmacology, Medical Faculty University of Zagreb, Croatia) | 2002 | Acta Pharmacologica Sinica2002，23，5： | 2 |
| 8 | Histological characteristics of sugar beet leaves potentially linked to drought tolerance显示文摘 | Jadranka LukoviC Ivana MaksimoviC Lana ZoriC | 2009 | Industrial Crops and Products2009，30，： | 1 |
| 9 | Prevalidation in pharmaceutical analysis(part I)Fundamentals and critical discussion显示文摘 | VLADIMIR G JADRANKA V | 2004 | J Pharm Biomed Anal2004，35，： | 1 |
| 10 | Socio-political factors and the failure of innovation policy in Croatia as a country in transition显示文摘 | Jadranka Svarc | 2006 | Research Policy2006，，35： | 1 |
| 11 | Complex coacervation in gelatin/sodium caseinate mixtures显示文摘 | Jadranka Milanovi? Lidija Petrovi? Verica Sovilj Jaroslav Katona | 2014 | Food Hydrocolloids2014，，： | 1 |
| 12 | Referentni rasponi hematolo?kih i biokemijskih pokazatelja u ovaca pasmine dalmatinska pramenka utvr?eni bootstrap metodom na malom uzorku.显示文摘 | Aleksandar Vojta Ana Shek-Vugrove?ki Lada Radin Ma?a Efendi? Jadranka Pejakovi? Miljenko ?impraga | 2011 | Veterinary Archives2011，，1： | 1 |
| 13 | Study of flammability and thermal properties of high-impact polystyrene nanocomposites显示文摘 | Zvonimir Katancic Jadranka Travas-Sejdic Zlata Hrnjak-Mur- gi | 2011 | Polymer Degradation ~ Stabil- ity2011，96，12： | 1 |
| 14 | Electrochemically controlled drug delivery based on intrinsically conducting polymers 显示文摘 | Darren S Jadranka T-S Anthony R | 2010 | Journal of Controlled Release2010，146，1： | 1 |
| 15 | Platelet-related hemostasis before and after-hemodialysis with five different anticoagulation methods显示文摘 | Masa K Rafael P Jadranka BP | 2013 | International Journalof Artificial Organs2013，36，36： | 1 |
| 16 | Svojstva biomedieinskih Co-Cr-Mo shitina显示文摘 | Prosper M Tanja M Jadranka M | 1998 | Metalurglja ( Metallurgy)1998，37，1： | 1 |
| 17 | Development and prevalidation of a method for phenol determination by solid - phase spectrophotome- try 显示文摘 | Jadranka V Shiro M Kazuhisa Y | 2007 | Microchim Acta2007，159，： | 1 |
| 18 | Comparison of sensory properties,shelf-life and microbiological safety of industrial sausages produced with autochthonous and commercial starter cultures显示文摘 | JADRANKA F DRAGAN K SNJEZANA K | 2014 | Food Technology and Biotechnology2014，52，3： | 1 |
| 19 | Effect of increased diaphragm activation on diaphragm power spectrum center frequency显示文摘 | JADRANKA S JENNIFER B LARS L | 2005 | Respiratory Physiology & Neurobiology2005，146，1： | 1 |
| 20 | Prevalidation in pharmaceutical analysis Part I:Fundamentals and critical discussion显示文摘 | Vladimir Grdinic Jadranka Vukovi | 2004 | Journal of Pharmaceutical and Biomedical Analysis2004，，35： | 1 |
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