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| 1 | Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame显示文摘导致的 pluripotent 的产生从体的细胞的茎(iPS ) 细胞被定义 reprogramming 抄写因素(TF ) 的同时的病毒的 transduction 成功地完成了。然而,这个过程为基因交货要求多重病毒的向量。作为结果,产生了 iPS 房间港口在他们的染色体的众多的病毒的集成地点。这能增加基因 mutagenesis 和 genomic 不稳定性的概率,并且介绍重要障碍给研究和 iPS 房间的临床的申请研究。在这篇论文,我们在场定义因素是的一个简单 lentivirus reprogramming 在系统经由自我劈开的 2A 序列熔化了在里面框架进一个单个开的读物框架(ORF ) 。一个 GFP 标记下游地被放 transgene 启用 transgene 表示追踪。我们证明这个 polycistronic 表示系统高效地产生 iPS 房间。产生 iPS 房间有正常 karyotypes 并且类似于鼠标在形态学和基因表示的胚胎的干细胞。而且,他们能在 vitro 并且在 vivo 试金在两个区分进三胚胎的细菌层的房间类型。显著地,大多数这些 iPS 房间仅仅怀有病毒的向量的一个单个拷贝。这个系统提供一个珍贵工具因为 iPS 房间的产生,和我们的数据建议在每个房间的 transduced reprogramming TF 的表示的平衡为 reprogramming 进程是必要的。更重要地,当由非集成的基因交货系统交付了时,这重新设计的单个 ORF 将没有基因修正便于人的 iPS 房间的有效产生。 | Lijian Shao Wei Feng Yan Sun Hao Bai Jun Liu Caroline Currie Jaejung Kim Rafael Gama Zack Wang Zhijian Qian Lucy Liaw Wen-Shu Wu | 2009 | Cell Research2009，19，3： | 12 |
| 2 | Highly efficient CdSe quantum-dot-sensitized TiO 2 photoelectrodes for solar cell applications显示文摘 | Sheng-Qiang Fan Duckhyun Kim Jeum-Jong Kim Dong Woon Jung Sang Ook Kang Jaejung Ko | 2009 | Electrochemistry Communications2009，，6： | 1 |
| 3 | Chemiluminescence properties of eopolyesters containing red and blue ehromophores 显示文摘 | Lee Chil-Won Joo Sang-Woo Ko Jaejung | 2002 | Synthetic Metals2002，126，6： | 1 |
| 4 | Malgun (Clear) Cell Change in Helicobacter pylori Gastritis Reflects Epithelial Genomic Damage and Repair显示文摘 | Jaejung Jang Seungkoo Lee Yusun Jung Kyuyoung Song Manabu Fukumoto Victor E. Gould Inchul Lee | 2003 | The American Journal of Pathology2003，，4： | 1 |
| 5 | “Malgun” (clear) Cell Change of Gastric Epithelium in Chronic Helicobacter pylori Gastritis显示文摘 | Hunkyung Lee Jaejung Jang Yunjung Kim Sangho Ahn Mikyung Gong Eunsuk Choi Inchul Lee | 2000 | Pathology - Research and Practice2000，，8： | 1 |
| 6 | Chemiluminescence properties of copolyesters containing red and blue chromophores显示文摘 | Lee Chil-Won Joo Sang-Woo Ko Jaejung | 2002 | Synthetic Metals2002，126，6： | 1 |
| 7 | Chemiluminescence properties of polymeric blue fluorophores containing diphenylanthracene unit显示文摘 | Park Hoon-Young Geum Neri Ko Jaejung | 2002 | Dyes and Pigments2002，54，7： | 1 |
| 8 | Super-resolution visible photoactivated atomic force microscopy显示文摘Imaging the intrinsic optical absorption properties of nanomaterials with optical microscopy(OM)is hindered by the optical diffraction limit and intrinsically poor sensitivity.Thus,expensive and destructive electron microscopy(EM)has been commonly used to examine the morphologies of nanostructures.Further,while nanoscale fluorescence OM has become crucial for investigating the morphologies and functions of intracellular specimens,this modality is not suitable for imaging optical absorption and requires the use of possibly undesirable exogenous fluorescent molecules for biological samples.Here we demonstrate super-resolution visible photoactivated atomic force microscopy(pAFM),which can sense intrinsic optical absorption with~8 nm resolution.Thus,the resolution can be improved down to~8 nm.This system can detect not only the first harmonic response,but also the higher harmonic response using the nonlinear effect.The thermoelastic effects induced by pulsed laser irradiation allow us to obtain visible pAFM images of single gold nanospheres,various nanowires,and biological cells,all with nanoscale resolution.Unlike expensive EM,the visible pAFM system can be simply implemented by adding an optical excitation sub-system to a commercial atomic force microscope. | Seunghyun Lee Owoong Kwon Mansik Jeon Jaejung Song Seungjun Shin HyeMi Kim Minguk Jo Taiuk Rim Junsang Doh Sungjee Kim Junwoo Son Yunseok Kim Chulhong Kim | 2017 | Light(Science & Applications)2017，6，1： | 0 |
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