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| 1 | Membrane fouling reduction through electrochemically regulating flocs aggregation in an electro-coagulation membrane reactor显示文摘Coupling coagulation and applied electric field is an efficient method to regulate cake layer porosity and hydrophilicity for alleviating ultrafiltration membrane(UF) fouling. However,the Al/Fe flocs aggregation behavior are induced from electric field and determine the cake layer structure, which has not been studied comparatively yet. Herein, the anti-fouling performance in an efficient electro-coagulation membrane reactor(ECMR, in which UF membrane modules are placed between electrodes) was investigated with Al/Fe anode and various electrochemical parameters from the viewpoint of regulating flocs aggregation.Both the cake layers formed from Al and Fe flocs under an electric field were more porous and hydrophilic in comparison with that formed without electric fields, resulting in an enhanced water flux under higher electric field strength. Comparing with Fe flocs, Al flocs had a faster growth rate and larger size, facilitating membrane pore block resistant, which was more pronounced in a higher current density. Furthermore, the cake layer formed from Al flocs was more porous than that formed from Fe flocs. Therefore, the anti-fouling performance of ECMR with Al anode was superior to that of ECMR with Fe anode. When the electric field strength increased from 0 to 10 V/cm, the normalized specific flux was improved from 71.2% to 89.4% for ECMR(Al) and from 48.1% to 70.1% for ECMR(Fe) at 30 min. | Kai Zhao Jingqiu Sun Chengzhi Hu Jiuhui Qu | 2019 | Journal of Environmental Sciences2019，31，9： | 6 |
| 2 | Arabidopsis transcription factor TCP4 represses chlorophyll biosynthesis to prevent petal greening显示文摘Green petals pose a challenge for pollinators to distinguish flowers from leaves,but they are valuable as a specialty flower trait.However,little is understood about the molecular mechanisms that underlie the development of green petals.Here,we report that CINCINNATA(CIN)-like TEOSINTE BRANCHED 1/CYCLOIDEA/PCF(TCP)proteins play key roles in the control of petal color.The septuple tcp2/3/4/5/10/13/17 mutant produced flowers with green petals due to chlorophyll accumulation.Expression of TCP4 complemented the petal phenotype of tcp2/3/4/5/10/13/17.We found that chloroplasts were converted into leucoplasts in the distal parts of wild-type petals but not in the proximal parts during flower development,whereas plastid conversion was compromised in the distal parts of tcp2/3/4/5/10/13/17 petals.TCP4 and most CIN-like TCPs were predominantly expressed in distal petal regions,consistent with the green–white pattern in wild-type petals and the petal greening observed in the distal parts of tcp2/3/4/5/10/13/17 petals.RNA-sequencing data revealed that most chlorophyll biosynthesis genes were downregulated in the white distal parts of wild-type petals,but these genes had elevated expression in the distal green parts of tcp2/3/4/5/10/13/17 petals and the green proximal parts of wild-type petals.We revealed that TCP4 repressed chlorophyll biosynthesis by directly binding to the promoters of PROTOCHLOROPHYLLIDE REDUCTASE(PORB),DIVINYL REDUCTASE(DVR),and SUPPRESSOR OF OVEREXPRESSION OF CO 1(SOC1),which are known to promote petal greening.We found that the conversion of chloroplasts to leucoplasts and the green coloration in the proximal parts of petals appeared to be conserved among plant species.Our findings uncover a major molecular mechanism that underpins the formation of petal color patterns and provide a foundation for the breeding of plants with green flowers. | Xinhui Zheng Jingqiu Lan Hao Yu Jingzhe Zhang Yi Zhang Yongmei Qin Xiao-Dong Su Genji Qin | 2022 | Plant Communications2022，3，4： | 4 |
| 3 | Real-time crash prediction on freeways using data mining and emerging techniques显示文摘Recent advances in intelligent transportation system allow traffic safety studies to extend from historic data-based analyses to real-time applications. The study presents a new method to predict crash likelihood with traffic data collected by discrete loop detectors as well as the web-crawl weather data. Matched case–control method and support vector machines(SVMs) technique were employed to identify the risk status. The adaptive synthetic over-sampling technique was applied to solve the imbalanced dataset issues. Random forest technique was applied to select the contributing factors and avoid the over-fitting issues. The results indicate that the SVMs classifier could successfully classify 76.32% of the crashes on the test dataset and 87.52% of the crashes on the overall dataset,which were relatively satisfactory compared with the results of the previous studies. Compared with the SVMs classifier without the data, the SVMs classifier with the web-crawl weather data increased the crash prediction1.72%, showing the potential value of the massive web weather data. Mean impact value method was employed to evaluate the variable effects, and the results are identical with the results of most of previous studies.are identical with the results of most of previous studies.The emerging technique based on the discrete traffic data and web weather data proves to be more applicable on realtime safety management on freeways. | Jinming You Junhua Wang Jingqiu Guo | 2017 | Journal of Modern Transportation2017，25，2： | 3 |
| 4 | Identification of the candidate genes associated with cellular rejection in pig-to-human xenotransplantation显示文摘To identify the genes associated with cellular rejection in pig-to-human xenotransplantation, the suppression subtractive hybridization (SSH) was used in screening the up-regulated genes from a co-culture of human peripheral blood mononuclear cells (PBMCs) and porcine vascular endothelial cell line PIEC. The up-regulated cDNAs were cloned into pGEM-T Easy vector and then sequenced. Nucleic acid homology searches were performed using the BLAST program. A subtracted cDNA library including about 300 clones with the expected up-regulated genes was obtained. Twenty-four of these clones were analyzed by sequencing and homology comparison was made. These clones represent the genes of human perforin (PRF1), proteasome, lymphocyte specific interferon regulatory factor/interferon regulatory factor 4 (LSIRF/IRF 4), muscleblind-like (MBNL) protein and a porcine expressed sequence tag (EST) which has 81% homology with human oxidative-stress responsive 1 (OSR 1). These genes might be the candidate genes which are associated with cellular rejection in pig-to-human xenotransplantation. | HU Weimin, CHENG Jingqiu, LI Youping , LI Shengfu, LU Xiaofeng and WAN Lin(Laboratory of Transplant Engineering and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China) | 2002 | Progress in Natural Science:Materials International2002，12，9： | 3 |
| 5 | Establishment of a rhesus monkey model of middle cerebral artery ischemia and reperfusion using a microcatheter embolization method显示文摘Nonhuman primates are closest to humans in terms of lineage,and middle cerebral artery ischemia/reperfusion responses of nonhuman primates are most similar to ischemic stroke in humans.Therefore,nonhuman primates could be utilized to simulate the process of ischemic stroke in the human.Few studies,however,have reported the use of endovascular technology to establish a rhesus monkey stroke model.In the present study,seven adult,male,rhesus monkeys were selected and,following anesthesia,a microcatheter was inserted into one side of the middle cerebral artery via the femoral artery to block blood flow,thereby resulting in middle cerebral artery occlusion.After 2 hours,the microcatheter was withdrawn to restore the middle cerebral artery blood flow and to establish ischemia/reperfusion.Results from angiography and magnetic resonance angiography confirmed occlusion and reopening of the middle cerebral artery.Magnetic resonance imaging revealed the existence of ischemic brain lesions,and neurological examination showed sustained functional deficits following surgery.The rhesus monkey middle cerebral artery ischemia/reperfusion models established by microcatheter embolization had the advantage of non-craniotomy invasion and reproducibility.The scope and degree of ischemic damage using this model was controllable.Therefore,this nonhuman primate model is an ideal model for cerebral ischemia and reperfusion. | Jie Yang Jian Guo Hongbo Zheng Muke Zhou Li He Wenying Cao Li Xiao Jiachuan Duan Qiyong Gong Xiaoqi Huang Hongxia Li Li Wang Jingqiu Cheng | 2010 | Neural Regeneration Research2010，5，15： | 2 |
| 6 | Design and Application of Third-order Denitration Online Control Technology显示文摘In order to alleviate the pressure of environmental protection and further strengthen the monitoring and control of NOx emission of thermal power units, combining with the transformation of boiler low-nitrogen burner, combustion optimization, static and dynamic ratio of air and coal, and SCR denitration system process, third-order NOx online control technology was designed and applied, which takes the combustion security, boiler efficiency and environmental evaluation into account and provide reference for thermal power units to deepen energy conservation and emission reduction. | Wang Li Wang Yanjin Kang Jingqiu | 2019 | Meteorological and Environmental Research2019，10，4： | 2 |
| 7 | Xenozoonoses in xenotransplantation显示文摘Pig to human xenotransplantation is one of the possible ways to solve the problem of organ shortage, but the potential risk of xenozoonoses hinders the progress of xenotransplantation. Among pathogens that might cause xenozoonoses, porcine endogenous retrovirus (PERV) is undoubtedly the most noticeable. Current researches show that PERV exists in pigs' genomes and is able to express in multiple tissues and organs in pigs. Other experiments also show that PERV could successfully infect several human cell lines in vitro and could infect SCID mice through pig to mouse islet transplantation. The discussion and research on the risk of PERV is one of the hottest topics in current xenotransplantation, but the question of whether PERV will transmit to human through xenotransplantation has not been answered due to the lack of suitable animal models. More work should be done to evaluate the risk of xenozoonoses caused by PERV after pig to human xenotransplantation. | ZHANG Li, BU Hong, LI Youping and CHENG Jingqiu(Key Laboratory of Transplant Engineering and Immunology, Ministry of Health, West China Hospital, Sichuan University, Chengdu 610041, China) | 2003 | Progress in Natural Science:Materials International2003，13，1： | 2 |
| 8 | Activation of Signal Transducer and Activator of Transcription 5 (STAT5) in Splenocyte Proliferation of Asthma Mice Induced by Ovalbumin显示文摘To investigate the role of signal transducer and transcriptional activator 5 (STAT5) activated in ovalbumin (OVA)-induced splenocyte proliferation of asthma mice, an asthma mouse model was set up by intraperitoneal injection and aspiration of OVA with nebulizer. The proliferation of splenocytes isolated from the asthma mice was detected by [3H] thymidine incorporation. The phosphorytation of STAT5 was examined by Western blotting and STAT5-DNA binding was measured by electrophoretic mobility shift assay (EMSA). OVA could pronouncedly induce the splenocyte proliferation of asthma mice in a dose-dependent manner compared with control groups. Phosphorylation of STAT5 and STAT5-DNA binding were observed in splenocytes from asthma mice induced by OVA at 1 h and 3 h. These results indicated that STAT5 signal pathway played an important role in lymphocyte proliferation of asthma mice induced by OVA. Cellular & Molecular Immunology.2004;1(6):471-474. | GuopingLi ZhigangLiu PeixingRan JingQiu NanshanZhong | 2004 | Cellular & Molecular Immunology2004，1，6： | 2 |
| 9 | 金台村重建项目,巴中,中国显示文摘金台村位于四川省巴中市南江县,是2008年512大地震受灾最严重的地区之一。该地震导致近500万人无家可归,受灾区据估计有80%的建筑受到不同程度的毁坏。灾后重建随即展开。然而2011年7月的一次大雨后,山体滑坡导致金台村附近许多刚建完及正在修建的房屋再次遭受破坏。尽管损失惨重,当地居民却无从获得任何额外援助。 | 林君翰 约书亚.伯尔乔夫 zhang jingqiu(译) | 2018 | 世界建筑2018，，8： | 2 |
| 10 | Separation and prepa- ration ofmacerals in Shenfu coals by flotation 显示文摘 | ShuXinqian Wang Zuna Xu Jingqiu | 2002 | Fuel2002，81，4： | 1 |
| 11 | A Study of Cultural Facilities Utilization Based on Questionnaires-A Case Study of Gymnasiums, Museums and Galleries in Beijing 显示文摘 | Shaolu Yu Jingqiu Zhang | 2009 | Asian Social Science2009，，4： | 1 |
| 12 | Numerical calculation of short-circuit electromagnetic forces on the transformer winding显示文摘 | TANG Yunqiu QIAO Jingqiu XU Zihong | | 0，，02： | 1 |
| 13 | Dye-Capping Gold Nanocluster:Photoinduced Morphological Changes in Gold/Rhodamine 6G Nanoassemblies显示文摘 | Nirmala Chandrasekharan Prashant V Kamat Jingqiu Hu Guilford Jones Ⅱ | 2000 | J Phys Chem B2000，104，11： | 1 |
| 14 | Locus of control and the three components of commitment to change显示文摘 | Jingqiu Chen Lei Wang | 2007 | Personality and lndivldual Differences2007，42，： | 1 |
| 15 | Recent advances in the managements of type 2 diabetes mellitus and natural hypoglycemic substances显示文摘Diabetes has become a global concern at present,among which type 2 diabetes mellitus(T2DM)accounts for approximately 90%-95%of patients.T2DM is a type of metabolic disorder syndrome that results from a genetic defect,and it is based on insulin resistance and an insulin secretion disorder.The occurrence of T2DM is usually the outcome of both genetic and environmental factors and their interactions.The etiology and pathogenesis of diabetes have not been fully elucidated,and no radical therapeutic cure has been found.Patients with T2DM suffer from complications such as the development of a chronic hyperglycemic condition and even serious metabolic disorders and organ damage in the body and depression and dementia,in addition to other chronic complications.Many studies have suggested that diet is crucial in the development of diabetes and the control of blood glucose.Natural substances have the characteristics of low toxicity and few side effects and may be key to the development of diabetic health products and preventive treatments.This paper reviews the etiology,pathogenesis,risks,treatments and diets related to T2DM to summarize the types of recently available natural products,from both local and foreign sources,for lowering blood glucose at home and their application in supplementary hypoglycemic foods.The key findings and conclusions suggest that there are various known T2DM-inducing factors,including genetic and environmental factors and three types of hybrid factors. | Chong Ning Yuhan Jiao Jiaqi Wang Weiwei Li Jingqiu Zhou Yi-Chieh Lee Dik-Lung Ma Chung-Hang Leung Rugang Zhu Hui-Min David Wang | 2022 | Food Science and Human Wellness2022，11，5： | 1 |
| 16 | Study on the fabrication of orange micro-LED arrays for display显示文摘 | Jin Xia Liang Jingqiu Wang Weibiao | 2005 | SPIE2005，6030，： | 1 |
| 17 | 靶向肾癌中的E3连接酶接头蛋白SPOP的小分子抑制剂显示文摘近年来肾癌发病率上升幅度在恶性肿瘤中排名第一。临床治疗表明,肾癌对放疗和化疗均不敏感,以索拉非尼和舒尼替尼为代表的靶向抗肿瘤药物是晚期肾癌的一线治疗药物,但对转移性肾癌的疗效十分有限,并且容易产生耐药。因此,发现并确证治疗肾癌特异性药物作用新靶标是一项十分紧迫并意义重大的任务。 | Zhong-Qiang Guo Tong Zheng Baoen Chen Cheng Luo Sisheng Ouyang Shouzhe Gong Jiafei Li Liu-Liang Mao Fulin Lian Yong Yang Yue Huang Li Li Jing Lu Bidong Zhang Luming Zhou Hong Ding Zhiwei Gao Liqun Zhou Guoqiang Li Ran Zhou Ke Chen Jingqiu Liu Yi Wen Likun Gong Yuwen Ke Shang-Dong Yang Xiao-Bo Qiu Naixia Zhang Jin Ren Dafang Zhong 杨财广 刘江 蒋华良 | 2017 | 科学新闻2017，19，4： | 1 |
| 18 | Design principles for the area density of dimple patterns显示文摘 | WANG Xiaolei WANG Jingqiu ZHANG Bo | 2015 | Proceedings of the Institution of Mechanical Engineers Part J: Journal of Engineering Tribology2015，229，4： | 1 |
| 19 | The Practical Value of Applying Chemical Biliary Duct Embolization to Chemical Hepatectomy for Treatment of Hepatolithiasis显示文摘 | Fuyu Li Jingqiu Cheng Sheng He Ning Li Mingming Zhang Jiahong Dong Lisheng Jiang Nansheng Cheng Xianzhe Xiong | 2005 | Journal of Surgical Research2005，，2： | 1 |
| 20 | Loss-of-function of sox3 causes follicle development retardation and reduces fecundity in zebrafish显示文摘Folliculogenesis is essential for production of female gametes in vertebrates.However,the molecular mechanisms underlying follicle development,particularly apoptosis regulation in ovary,remain elusive.Here,we gen erated sox3 knockout zebrafish lines using CRISPR/Cas9.sox3 knockout led to follicle development retardation and a reduced fecundity in females.Comparative analysis of transcriptome between sox3^-/-and wild-type ovaries revealed that Sox3 was invoIved in pathways of ovarian steroidogenesis and apoptosis.Knockout of sox3 promoted follicle apoptosis and obvious apoptosis signals were detected in somatic cells of stages III and IV follicles of sox3^-/-ovaries.Moreover,Sox3 can bind to and activate the promoter of cyp19a1a.Up-regulation of Cyp19a1a expression promoted 17β-estradiol synthesis,which inhibited apoptosis in follicle development.Thus,Sox3 functions as a regulator of Cyp19a1a expression,via 17β-E2 linking apoptosis suppression,which is implicated in improving female fecundity. | Qiang Hong Cong Li Ruhong Ying Heming Lin Jingqiu Li Yu Zhao Hanhua Cheng Rongjia Zhou | 2019 | Protein & Cell2019，10，5： | 1 |
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