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| 1 | Cancer stem cell markers CD133 and CD24 correlate with invasiveness and differentiation in colorectal adenocarcinoma显示文摘AIM:To verify that CD markers are available for detecting cancer stem cell populations and to evaluate their clinical significance in colon cancer.METHODS:Immunohistochemistry for CD133,CD24 and CD44 was performed on the tissue microarray of 523 colorectal adenocarcinomas.Medical records were reviewed and clinicopathological analysis was performed.RESULTS:In colorectal adenocarcinoma,128 of 523 cases(24.5%) were positive and 395 cases(75.5%) were negative for CD133 expression.Two hundred and sixty-four of 523 cases(50.5%) were positive and 259 cases(49.5%) were negative for CD24 expression.Five hundred and two of 523 cases(96%) were negative and 21 cases(4%) were positive for CD44 expression.Upon clinicopathological analysis,CD133 expression was present more in male patients(P = 0.002) and in advanced T stage cancer(P = 0.024).Correlation between CD24 expression and clinicopathological factors was seen in the degree of differentiation(P = 0.006).Correlation between CD44 expression and clinicopathological factors was seen in the tumor size(P = 0.001).Survival was not significantly related to CD133,CD24 and CD44 expression.CONCLUSION:CD markers were related to invasiveness and differentiation of colorectal adenocarcinoma.However,CD expression was not closely related to survival. | Dongho Choi Hyo Won Lee Kyung Yul Hur Jae Joon Kim Gyeong-Sin Park Si-Hyong Jang Young Soo Song Ki-Seok Jang Seung Sam Paik | 2009 | World Journal of Gastroenterology2009,15,18: | 14 |
| 2 | Undiagnosed Borrmann type Ⅱ gastric cancer due to necrosis and regenerative epithelium显示文摘Endoscopic biopsy is essential to the proper diagnosis and treatment of gastric cancer.Unfortunately,the results of endoscopic biopsy are not always the same as what is expected based on gross endoscopic findings.The results of endoscopic biopsy can be negative for malignancy in Borrmann typeⅣadvanced gastric cancer(AGCa)or gastric lymphoma.However,in the case of typeⅡAGCa,repeated biopsies negative for malignancy have not been reported.A 49-year-old male patient underwent esophagogastroduodenoscopy three times due to large gastric ulcer suspected to be Borrmann typeⅡcancer.However,three repeat endoscopic biopsies with multiple specimens showed necrosis and superficial regenerative epithelium without malignant findings.The patient underwent laparoscopic distal gastrectomy with D2 lymph node dissection.The surgical specimen revealed that the mucosal layer was completely replaced with regenerative epithelium without cancer cells. | Joon Hur Jae Hyuck Chang Byung Kee Kim Hoon Young Ko Jong Hwan Lee Soo Jeong Kim Mi Ae Song Tae Ho Kim Chang Whan Kim Sok Won Han | 2014 | World Journal of Gastroenterology2014,20,28: | 2 |
| 3 | Laparoscopy-Assisted Endoscopic Full-Thickness Resection with Basin Lymphadenectomy Based on Sentinel Lymph Nodes for Early Gastric Cancer显示文摘 | Hoon Hur Sun Gyo Lim Cheulsu Byun Joon Koo Kang Sung Jae Shin Kee Myung Lee Jin Hong Kim Yong Kwan Cho Sang-Uk Han | 2014 | Journal of the American College of Surgeons2014,,3: | 2 |
| 4 | CD133 + liver cancer stem cells modulate radioresistance in human hepatocellular carcinoma显示文摘 | Lian Shu Piao Wonhee Hur Taek-Kyun Kim Sung Woo Hong Sung Woo Kim Jung Eun Choi Pil Soo Sung Myeong Joon Song Byeong-Chel Lee Daehee Hwang Seung Kew Yoon | 2011 | Cancer Letters2011,,2: | 2 |
| 5 | Nomogram for prediction of pathologic complete remission using biomarker expression and endoscopic finding after preoperative chemoradiotherapy in rectal cancer显示文摘Objective:The aim of this study is to develop a nomogram for prediction of pathologic complete remission(p CR)after preoperative chemoradiotherapy(CRT)for rectal cancer.Methods:m RNA expression levels of seven molecular markers[p53,p21,Ki-67,vascular endothelial growth factor(VEGF),CD133,CD24,CD44]were measured by reverse transcriptase polymerase chain reaction(RTPCR)in 120 rectal cancers.Endoscopic findings of clinical complete remission(c CR)and biologic variables were used to construct nomogram in the training group(n=80),which was validated in the validation group(n=40).Results:m RNA expression levels of four markers(p53,p21,Ki67,CD133)correlated with p CR(24/80,30.0%)in the training group.Low expression of p53 and/or high expression of p21,Ki67 and CD133 showed greater p CR rate.p CR was shown in 18(69.2%)of 26 cases showing endoscopic c CR in the training group.Higher p CR rate was demonstrated in lower tumor location than middle tumor(19/49,38.8%vs.5/31,16.1%).A nomogram for prediction of p CR was developed from the multivariate prediction model using these six variables,which showed good discrimination ability in the training group[area under the curve(AUC)=0.945]and validation group(AUC=0.922).The calibration plot showed good agreement between actual and predicted p CR in both patient groups.Conclusions:Nomogram for assessment of p CR can be useful for making treatment decisions after CRT according to predicted responses. | Hyuk Hur Min Soo Cho Woong Sub Koom Joon Seok Lim Tae Il Kim Joong Bae Ahn Hoguen Kim Nam Kyu Kim | 2020 | Chinese Journal of Cancer Research2020,32,2: | 2 |
| 6 | Relationship Between Visceral Adiposity and Bone Mineral Density in Korean Adults显示文摘 | Han Seok Choi Kwang Joon Kim Kyoung Min Kim Nam Wook Hur Yumie Rhee Dae Suk Han Eun Jig Lee Sung-Kil Lim | 2010 | Calcified Tissue International2010,,3: | 1 |
| 7 | Digestion of municipal sludge by anaerobic sequencing batch reactor显示文摘 | Hur Joon Moo Chung Tai Hak | 1994 | Water Science and Technology1994,30,12: | 1 |
| 8 | Magnetic resonance imaging findings of the mass‐forming type of autoimmune pancreatitis: Comparison with pancreatic adenocarcinoma显示文摘 | Bo Yun Hur Jeong Min Lee Jeong Eun Lee Jae Yong Park Soo Jin Kim Ijin Joo Cheong Il Shin Jee Hyun Baek Jung Hoon Kim Joon Koo Han Byung Ihn Choi | 2012 | J Magn Reson Imaging2012,,1: | 1 |
| 9 | Digestion of municipal sludge by anaerobic sequencing batch reactor显示文摘 | Hur Joon Moo Tai Hak Chung | 1994 | Water Science and Technology1994,30,12: | 1 |
| 10 | Dynamic process response to sludge thickening behaviors in the anaerobic sequencing batch reactor treating high-solids-content waste 显示文摘 | Hur Joon Moo Chang Duck Chung Tai Hak | 1999 | Journal of Bioscience and Bioengineering1999,87,4: | 1 |
| 11 | Dynamic process response to sludge thickening behaviors in the anaerobic sequencing batch reactor treating high-solids-content waste显示文摘 | Chang Duck Chung Tai Hak | 1999 | Journal of Bioscience and Bioengineering1999,87,4: | 1 |
| 12 | New approaches to pathogenic gene function discovery with human squamous cell cervical carcinoma by gene ontology显示文摘 | Min-Jae Seo Su Mi Bae Yong-Wan Kim Yong Wook Kim Soo Young Hur Duck Young Ro Joon Mo Lee Sung Eun Namkoong Chong Kook Kim Woong Shick Ahn | 2004 | Gynecologic Oncology2004,,3: | 1 |
| 13 | CD133 + liver cancer stem cells modulate radioresistance in human hepatocellular carcinoma显示文摘 | Lian Shu Piao Wonhee Hur Taek-Kyun Kim Sung Woo Hong Sung Woo Kim Jung Eun Choi Pil Soo Sung Myeong Joon Song Byeong-Chel Lee Daehee Hwang Seung Kew Yoon | 2011 | Cancer Letters2011,,2: | 1 |
| 14 | Thymidylate Synthase Gene Polymorphism Affects the Response to Preoperative 5-Fluorouracil Chemoradiation Therapy in Patients With Rectal Cancer显示文摘 | Hyuk Hur Jeonghyun Kang Nam Kyu Kim Byung Soh Min Kang Young Lee Sang Joon Shin Ki Chang Keum Junjeong Choi Hoguen Kim Sung Ho Choi Mi-Young Lee | 2011 | International Journal of Radiation Oncology Biology Physics2011,,3: | 1 |
| 15 | SSJD14101300021761显示文摘 | Hee Joon Kim Choong Young Kim Young Hoe Hur Yang Seok Koh Jung Chul Kim Hyun Jong Kim Chol Kyoon Cho | 2014 | Surgery Today2014,,10: | 1 |
| 16 | Mature Landfill Leachate Treatment from an Abandoned Municipal Waste Disposal Site显示文摘 | Joon Moo Hur Jong An Park Bu Soon Son | 2001 | KoreanZ ChemEng2001,8,2: | 1 |
| 17 | Volumetric analysis and indocyanine green retention rate at 15 min as predictors of post‐hepatectomy liver failure显示文摘 | Hee Joon Kim Choong Young Kim Eun Kyu Park Young Hoe Hur Yang Seok Koh Hyun Jong Kim Chol Kyoon Cho | 2015 | HPB2015,,2: | 1 |
| 18 | Treatment of ovarian cancer with paclitaxel- or carboplatin-based intraperitoneal hyperthermic chemotherapy during secondary surgery显示文摘 | Jeong Hoon Bae Joon Mo Lee Ki Sung Ryu Yong Seok Lee Yong Gyu Park Soo Young Hur Woong Shik Ahn Seong Eun Namkoong | 2007 | Gynecologic Oncology2007,,1: | 1 |
| 19 | A prospective phase II trial of S-1 and cisplatin-based chemoradiotherapy for locoregionally advanced esophageal cancer显示文摘 | Hyun Chang Sung Kwan Shin Byoung Chul Cho Chang-Geol Lee Choong Bai Kim Dae Joon Kim Jin Gu Lee Jin Hur Chang Young Lee Mi Kyung Bae Hye Ryun Kim Sang Kil Lee Jun Chul Park Hyuk Lee Hyoung-Il Kim Hyunsoo Chung Jihye Cha Yong Chan Lee Joo-Hang Kim | 2014 | Cancer Chemotherapy and Pharmacology2014,,: | 1 |
| 20 | CD133 + liver cancer stem cells modulate radioresistance in human hepatocellular carcinoma显示文摘 | Lian Shu Piao Wonhee Hur Taek-Kyun Kim Sung Woo Hong Sung Woo Kim Jung Eun Choi Pil Soo Sung Myeong Joon Song Byeong-Chel Lee Daehee Hwang Seung Kew Yoon | 2011 | Cancer Letters2011,,2: | 1 |