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| 1 | Features of extrahepatic metastasis after radiofrequency ablation for hepatocellular carcinoma显示文摘BACKGROUND Extrahepatic metastasis(EHM)of hepatocellular carcinoma(HCC)is associated with poor outcomes.However,the clinical features and risk factors of EHM of HCC after radiofrequency ablation(RFA)remain unclear.AIM To elucidate the characteristics and risk factors of EHM after RFA for HCC.METHODS From January 2008 to December 2017,we retrospectively enrolled 661 patients who underwent RFA as first-line treatment for HCC at 2 tertiary hospitals.The inclusion criteria were age≥18 years,a diagnosis of HCC,and treatment-naivety.Abdominal computed tomography(CT)or magnetic resonance imaging(MRI)and alpha-fetoprotein measurements were routinely performed at 1 mo after RFA and followed-up at intervals of 3-6 mo.Univariate analyses were performed using the chi-squared test or Student’s t-test,and univariate and multivariate analyses were performed via logistic regression,as appropriate.RESULTS EHM was diagnosed in 44 patients(6.7%)during a median follow-up period of 1204 days.The 10-year cumulative rate of HCC recurrence and EHM was 92.7%and 33.7%,respectively.Initial recurrence was most often intrahepatic,and the rate of extrahepatic recurrence at initial recurrence was only 1.2%.The median time to the diagnosis of EHM was 2.68 years,and 68.2%of patients developed EHM within 2 years of the first recurrence,regardless of recurrence-free survival and 75.0%of patients developed EHM within 5 years after first recurrence.EHM was mostly diagnosed via abdominal CT/MRI in 33(75.0%)and 38 of 44 patients(86.4%)with EHM had either positive abdominal CT scan results or serum AFP level elevation.In multivariate analysis,recurrence-free survival<2 years,ablation zone/tumor size<2,and alpha-fetoprotein level>400 IU/mL were associated with a high EHM risk.CONCLUSION EHM occurs following multiple intrahepatic recurrences after RFA and combined contrast-enhanced abdominal CT and serum AFP were useful for surveillance.Patients especially with high-risk factors require close follow-up for EHM. | Jae H Yoon Young J Goo Chae-Jun Lim Sung K Choi Sung B Cho Sang S Shin Chung H Jun | 2020 | World Journal of Gastroenterology2020，26，32： | 3 |
| 2 | Experiments on Vision Guided Docking of an Autonomous Underwater Vehicle Using One Camera 显示文摘 | Park J Y Jun B H | 2009 | Ocean Engineering2009，36，1： | 1 |
| 3 | Fuzzy filters of MTL-algebras显示文摘 | Jun Y B Xu Y Zhang X H | 2005 | Information Sciences2005，175，： | 1 |
| 4 | ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery显示文摘 | JUNG C H JUN C B RO S H | 2009 | Molecular Biology of the Cell2009，20，7： | 1 |
| 5 | Evolution of Precipitates in the Nb-Ti-V Microalloyed HSLA Steels During Reheating 显示文摘 | Hong S G Jun H J Kang K B | 2003 | Seripta Materialia2003，48，： | 1 |
| 6 | Cyclophosphamide inhibits the development of diabetes in the diabetes-prone BB rat 显示文摘 | Sobel D O Ahvazi B Jun H S | 2000 | Diabetologia2000，43，8： | 1 |
| 7 | Applications of soft sets in ideal theory of BCK/BCI-algebras显示文摘 | Jun Y B Park C H | 2008 | Information Sciences2008，178，： | 1 |
| 8 | Experiments on vision guideddocking of an autonomous underwater vehicle using one cam-era显示文摘 | Park J Y Jun B H Lee P M | 2009 | Ocean Engineering2009，36，1： | 1 |
| 9 | Synthesis of dimethyl carbonate from CH3OH and CO2 with Ce1-xZrx O2 catalysts 显示文摘 | Han G B Park N K Jun J H | 2004 | Studies in Surface Science and Catalysis2004，153，： | 1 |
| 10 | H-ideals in lattice implication algebras显示文摘 | Jun Y B Roh E H Xu Yang | 1998 | Bull Korean Math Soc1998，35，1： | 1 |
| 11 | On L-fuzzy ideals in semiring I 显示文摘 | Jun Y B Chinju Neggers J Tuscaloosa Kim H S Chongju | 1998 | Czechoslovak Mathematical Journal1998，48，4： | 1 |
| 12 | Fuzzy soft set theory applied to BCK/BCI algebras显示文摘 | Jun Y B Lee K J Park C H | 2010 | Computers and Mathematics with Applications2010，59，： | 1 |
| 13 | Occurrence and removal of pharmaceuti- cals, caffeine and DEET in wastewater treatment plants of Beijing, Chi- na显示文摘 | Qian S Jun H Shu B | 2010 | Water Research2010，44，： | 1 |
| 14 | A Hierarchical Real-Time Control Architecture for a Semi-Autonomous Underwater Vehicle 显示文摘 | Li J H Jun B H Pan M L | 2005 | Ocean Engineering2005，32，13： | 1 |
| 15 | Characterization of urban stormwater runoff显示文摘 | Jun H L Woong B | 2000 | Water Resources2000，34，6： | 1 |
| 16 | Fuzzy filters of MTL-algebras显示文摘 | Jun Y B Xu Y Zhang X H | 2005 | Information Sciences2005，175，： | 1 |
| 17 | Adaptive probabilities of crossover and mutation in genetic algorithms 显示文摘 | ZHANG Jun CHUNG H S H HU B J | 1994 | IEEE Trans Syst Man and Cybernetics1994，24，4： | 1 |
| 18 | Comparative study of YBCO film growth in the cold wall type and hot wall type MOCVD processes 显示文摘 | Kim C J Jun B H Kim H J et ell | 2005 | Physica C : Superconductivity and its Applications2005，，： | 1 |
| 19 | Polymerization of aqueous lactic acid to prepare high molecular weight poly(lactic acid) by chain extending with hexamethylone diisocyannate显示文摘 | Kim B O Jun H S | 1995 | Poly Bull1995，35，4： | 1 |
| 20 | Polymerization ofaqueous lactic acid to prepare high molecular weightpoly(lactic acid)by chain-extending with hexamethylenediisocyanate显示文摘 | WOO S I KIM B O JUN H S | 1995 | Polym Bull1995，35，4： | 1 |
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