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| 1 | Multifunctional core/satellite polydopamine@Nd^3+- sensitized upconversion nanocomposite: A single 808 nm near-infrared light-triggered theranostic platform for in vivo imaging-guided photothermal therapy显示文摘重要变细并且过热,在水里由刺激乐队(980 nm ) 的吸收引起了,是主要障碍在在里面做 lanthanide 的 upconversion nanoparticles (UCNP ) 的 vivo 申请。因此,有 808 nm 刺激的适当地组织的 Nd 3+-doped UCNP 能是一种有希望的选择。此处,我们开发了 core-shell-shell 作为成像代理人组织了 Nd 3+-sensitized UCNP,并且装饰了他们到 polydopamine (PDA ) 的表面上构造新奇多功能的核心 / 卫星 nanotheranostic (PDA@UCNPs ) 为在 vivo 成像指导 photothermal 治疗使用单身者 808 nm 激光照耀。core-shell-shell 组织了设计启用的突出的 upconversion 光性质和强壮的 X 光检查变细,从而为优秀 upconversion luminescence/computed 断层摄影术使 nanocomposites 成为潜在的候选人双形式的成像。另外, PDA 核心不仅提供高 photothermal 变换效率和突出的 antitumor 效果,而且由于它的自然特征赋予站台以柔韧的 biocompatibility。因此,这多功能的 nanocomposite 能是在未来 oncotherapy 的有希望的 theranostic,与高治疗学的有效性但是低副作用。这研究将刺激在设计 bio-application-compatible 使多功能的 nanocomposites 感兴趣,特别为在 vivo 的癌症诊断和治疗。 | Xing Ding Jianhua Liu Dapeng Liu Junqi Li Fan Wang Leijiao Li Yinghui Wang Shuyan Song Hongjie Zhang | 2017 | Nano Research2017，10，10： | 16 |
| 2 | 2-Year GLOBE Trial Results: Telbivudine Is Superior to Lamivudine in Patients With Chronic Hepatitis B显示文摘 | Yun–Fan Liaw Edward Gane Nancy Leung Stefan Zeuzem Yuming Wang Ching Lung Lai E. Jenny Heathcote Michael Manns Natalie Bzowej Junqi Niu Steven–Huy Han Seong Gyu Hwang Yilmaz Cakaloglu Myron J. Tong George Papatheodoridis Yagang Chen Nathaniel A. Brown Efs | 2009 | Gastroenterology2009，，2： | 13 |
| 3 | Expert consensus on dental caries management显示文摘Dental Caries is a kind of chronic oral disease that greatly threaten human being’s health.Though dentists and researchers struggled for decades to combat this oral disease,the incidence and prevalence of dental caries remain quite high.Therefore,improving the disease management is a key issue for the whole population and life cycle management of dental caries.So clinical difficulty assessment system of caries prevention and management is established based on dental caries diagnosis and classification.Dentists should perform oral examination and establish dental records at each visit.When treatment plan is made on the base of caries risk assessment and carious lesion activity,we need to work out patient-centered and personalized treatment planning to regain oral microecological balance,to control caries progression and to restore the structure and function of the carious teeth.And the follow-up visits are made based on personalized caries management.This expert consensus mainly discusses caries risk assessment,caries treatment difficulty assessment and dental caries treatment plan,which are the most important parts of caries management in the whole life cycle. | Lei Cheng Lu Zhang Lin Yue Junqi Ling Mingwen Fan Deqin Yang Zhengwei Huang Yumei Niu Jianguo Liu Jin Zhao Yanhong Li Bin Guo Zhi Chen Xuedong Zhou | 2022 | International Journal of Oral Science2022，14，2： | 8 |
| 4 | Mass production of Co3O4@CeO2 core@shell nanowires for catalytic CO oxidation显示文摘在这研究,公司 3 O 4@CeO2 core@shell nanowires 成功地经由公司的热分解被准备(公司 3)0.5(OH) | Jiangman Zhen Xiao Wang Dapeng Liu Zhuo Wang Junqi Li Fan Wang Yinghui Wang Hongjie Zhang | 2015 | Nano Research2015，8，6： | 4 |
| 5 | Solid ion transition route to 3D S-N-codoped hollow carbon nanosphere/graphene aerogel as a metal-free handheld nanocatalyst for organic reactions显示文摘新奇没有金属的体积 nanocatalyst, S-N-codoped 空碳 nanosphere/graphene aerogel (SNC-GA-1000 ) ,成功地用一条灵巧、干净的稳固的离子转变线路被制作了。在这个方法, ZnS 被用作难模板和 S 来源,当 polydopamine 充当一个减少的代理人和碳来源时。在高退火温度, Zn 金属被减少并且蒸发,离开仅仅自由的 S 蒸汽扩散进碳层。有趣地,同样获得的 SNC-GA-1000 比卸掉的赤裸的 S-N-codoped 碳 nanospheres 在器官的减小反应展出许多更高催化的活动。与 ZnS@polydopamine 核心壳 nanospheres (ZnS@PDA ) 装载的 graphene 氧化物表的热水的减小负担得起三维的体积 graphene aerogel。尽管 nanosized 催化剂展出高催化的活动,他们的随后的分离不总是是令人满意的,成为处理以后困难。这条途径完成在活动和可分性之间的一宗交易。更重要地,由于 3D,结构的自然,如此的体积和手持 nanocatalysts 能容易被分开并且再循环。 | Jing Pan Shuyan Song Junqi Li Fan Wang Xin Ge Shuang Yao Xiao Wang Hongjie Zhang | 2017 | Nano Research2017，10，10： | 3 |
| 6 | 2-Year GLOBE Trial Results: Telbivudine Is Superior to Lamivudine in Patients With Chronic Hepatitis B显示文摘 | Yun–Fan Liaw Edward Gane Nancy Leung Stefan Zeuzem Yuming Wang Ching Lung Lai E. Jenny Heathcote Michael Manns Natalie Bzowej Junqi Niu Steven–Huy Han Seong Gyu Hwang Yilmaz Cakaloglu Myron J. Tong George Papatheodoridis Yagang Chen Nathaniel A. Brown Efs | 2009 | Gastroenterology2009，，2： | 1 |
| 7 | Diamond & Related Materials显示文摘 | Xu Junqi Fan Huiqing Liu Weiguo | 2008 | 17(2):1942008，17，2： | 1 |
| 8 | Diamond & Related Materials显示文摘 | Xu Junqi Fan Huiqing Kousaka Hiroyuki | 2007 | 16(1):1612007，16，1： | 1 |
| 9 | Surface & Coating Technology显示文摘 | Xu Junqi Fan Huiqing Kousaka Hiroyuki | 2007 | 201(15):66312007，201，15： | 1 |
| 10 | Problems of durability and reinforcement measures for underground structures in China显示文摘In this paper,the bolt-and cable-supported structures mainly refer to anchored cables,anchored bolts,soil nails and other commonly used reinforcing and supporting structures in geotechnical engineering,as well as reinforced soil structures in permanent works.They are often used in combination,or formed into composite bolt-and cable-supported structures,with other traditional construction methods and relevant measures.Distinct characteristics of such structures are that they are most often invisible,exposed to more severe underground corrosive environments and with strict durability requirements.A number of serious durability problems of underground structures are discussed and major achievements and advances in China and abroad in terms of durability and reinforcement measures for underground structures are reviewed,followed by comprehensive analyses.Some suggestions for those problems are put forward. | Xianming Zeng Zhenyu Wang Junqi Fan Lin Zhao Dalu Lin Jian Zhao | 2011 | Journal of Rock Mechanics and Geotechnical Engineering2011，3，3： | 1 |
| 11 | 2-Year GLOBE Trial Results: Telbivudine Is Superior to Lamivudine in Patients With Chronic Hepatitis B显示文摘 | Yun–Fan Liaw Edward Gane Nancy Leung Stefan Zeuzem Yuming Wang Ching Lung Lai E. Jenny Heathcote Michael Manns Natalie Bzowej Junqi Niu Steven–Huy Han Seong Gyu Hwang Yilmaz Cakaloglu Myron J. Tong George Papatheodoridis Yagang Chen Nathaniel A. Brown Efs | 2009 | Gastroenterology2009，，2： | 1 |
| 12 | An asynchronous and synchronous coupling approach in the networked rapid product development显示文摘 | NI Yanrong FAN Feiya YAN Junqi | 2003 | International Journal of Advance Manufacturing Technology2003，22，12： | 1 |
| 13 | 2-Year GLOBE Trial Results: Telbivudine Is Superior to Lamivudine in Patients With Chronic Hepatitis B显示文摘 | Yun–Fan Liaw Edward Gane Nancy Leung Stefan Zeuzem Yuming Wang Ching Lung Lai E. Jenny Heathcote Michael Manns Natalie Bzowej Junqi Niu Steven–Huy Han Seong Gyu Hwang Yilmaz Cakaloglu Myron J. Tong George Papatheodoridis Yagang Chen Nathaniel A. Brown Efs | 2009 | Gastroenterology2009，，2： | 1 |
| 14 | Junctional and somatic hypermutation-induced CX4C motif is critical for the recognition of a highly conserved epitope on HCV E2 by a human broadly neutralizing antibody显示文摘Induction of broadly neutralizing monoclonal antibodies(bNAbs)that bind to the viral envelope glycoproteins is a major goal of hepatitis C virus(HCV)vaccine research.The study of bNAbs arising in natural infection is essential in this endeavor.We generated a human antibody,8D6,recognizing the E2 protein of HCV isolated from a chronic hepatitis C patient.This antibody shows broadly neutralizing activity,which covers a pan-genotypic panel of cell culture-derived HCV virions(HCVcc).Functional and epitope analyses demonstrated that 8D6 can block the interaction between E2 and CD81 by targeting a highly conserved epitope on E2.We describe how the 8D6 lineage evolved via somatic hypermutation to achieve broad neutralization.We found that the V(D)J recombination-generated junctional and somatic hypermutation-induced disulfide bridge(C-C)motif in the CDRH3 is critical for the broad neutralization and binding activity of 8D6.This motif is conserved among a series of broadly neutralizing HCV antibodies,indicating a common binding model.Next,the 8D6 inferred germline(iGL)was reconstructed and tested for its binding affinity and neutralization activity.Interestingly,8D6 iGL-mediated relatively strong inhibition of the 1b genotype PR79L9 strain,suggesting that PR79L9 may serve as a potential natural viral strain that provides E2 sequences that induce bNAbs.Overall,our detailed epitope mapping and genetic studies of the HCV E2-specific mAb 8D6 have allowed for further refinement of antigenic sites on E2 and reveal a new mechanism to generate a functional CDRH3,while its iGL can serve as a probe to identify potential HCV vaccine strains. | Chunyan Yi Jing Xia Lan He Zhiyang Ling Xuesong Wang Yu Yan Jiangjun Wang Xinhao Zhao Weiguo Fan Xiaoyu Sun Ronghua Zhang Sheng Ye Rongguang Zhang Yongfen Xu Liyan Ma Yaguang Zhang Honglin Zhou Zhong Huang Junqi Niu Gang Long Junxia Lu Jin Zhong Bing Sun | 2021 | Cellular & Molecular Immunology2021，18，3： | 0 |
| 15 | Study on Optimization of Culture Conditions for Wild Isaria cicadae Miquel Liquid Strain显示文摘[Objectives] To study the effect of different culture conditions on the growth of wild I. cicadae Miq. liquid strain. [Methods]The I. cicadae Miq. strain was inoculated into the liquid culture medium with different carbon sources,nitrogen sources,micronutrients and p H,cultured in the constant temperature shaking incubator with rotating speed of 120 r/min at 19℃,and the mycelium pellet diameter,density and weight were compared between different treatments. [Results] The results showed that the optimum components of I. cicadae Miq.strain liquid included soluble starch,milk powder and vitamin B_(12),and the optimum p H was 5. 0-6. 0. [Conclusions] Soluble starch was the most suitable carbon source for the culture medium of I. cicadae Miq. liquid strain; milk powder was the most suitable nitrogen source for the culture medium of I. cicadae Miq. liquid strain; the most suitable p H was 5. 0-9. 0 for the mycelial growth of I. cicadae Miq.; the formula and mixture ratio of the optimum culture medium for the growth of liquid strain were determined. | Chunqin XIE Zheng CAO Junmin FAN Junqi XU Jun JIA | 2018 | Medicinal Plant2018，9，1： | 0 |
| 16 | Expert consensus on irrigation and intracanal medication in root canal therapy显示文摘Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear. The vapor lock effect in the apical region has yet to be solved, impeding irrigation efficacy and resulting in residual infections and compromised treatment outcomes. | Xiaoying Zou Xin Zheng Yuhong Liang Chengfei Zhang Bing Fan Jingping Liang Junqi Ling Zhuan Bian Qing Yu Benxiang Hou Zhi Chen Xi Wei Lihong Qiu Wenxia Chen Wenxi He Xin Xu Liuyan Meng Chen Zhang Liming Chen Shuli Deng Yayan Lei Xiaoli Xie Xiaoyan Wang Jinhua Yu Jin Zhao Song Shen Xuedong Zhou Lin Yue | 2024 | International Journal of Oral Science2024，16，1： | 0 |
| 17 | A Method for Predicting Service Deprecation in Service Systems显示文摘An increasing number of web services are being invoked by users to create user applications(e.g.,mashups). However, over time, a few good services in service systems have become deprecated, i.e., the service is initially available and is invoked by service users, but later becomes unavailable. Therefore, the prediction of service deprecation has become a key issue in creating reliable long-term user applications. Most existing research has overlooked service deprecation in service systems and has failed to consider long-term service reliability when making service recommendations. In this paper, we propose a method for predicting service deprecation, which comprises two components: Service Comprehensive Feature Modeling(SCFM) for extracting service features relevant to service deprecation and Deprecated Service Prediction(DSP) for building a service deprecation prediction model. Our experimental results on a real-world dataset demonstrate that our method yields an improved Area-Under-the-Curve(AUC) value over existing methods and thus has better accuracy in service deprecation prediction. | Bofei Xia Yushun Fan Cheng Wu Bing Bai Junqi Zhang | 2017 | Tsinghua Science and Technology2017，22，1： | 0 |
| 18 | Stock Price Forecasting: An Echo State Network Approach显示文摘Forecasting stock prices using deep learning models suffers from pro-blems such as low accuracy,slow convergence,and complex network structures.This study developed an echo state network(ESN)model to mitigate such pro-blems.We compared our ESN with a long short-term memory(LSTM)network by forecasting the stock data of Kweichow Moutai,a leading enterprise in China’s liquor industry.By analyzing data for 120,240,and 300 days,we generated fore-cast data for the next 40,80,and 100 days,respectively,using both ESN and LSTM.In terms of accuracy,ESN had the unique advantage of capturing non-linear data.Mean absolute error(MAE)was used to present the accuracy results.The MAEs of the data forecast by ESN were 0.024,0.024,and 0.025,which were,respectively,0.065,0.007,and 0.009 less than those of LSTM.In terms of con-vergence,ESN has a reservoir state-space structure,which makes it perform faster than other models.Root-mean-square error(RMSE)was used to present the con-vergence time.In our experiment,the RMSEs of ESN were 0.22,0.27,and 0.26,which were,respectively,0.08,0.01,and 0.12 less than those of LSTM.In terms of network structure,ESN consists only of input,reservoir,and output spaces,making it a much simpler model than the others.The proposed ESN was found to be an effective model that,compared to others,converges faster,forecasts more accurately,and builds time-series analyses more easily. | Guang Sun Jingjing Lin Chen Yang Xiangyang Yin Ziyu Li Peng Guo Junqi Sun Xiaoping Fan Bin Pan | 2021 | Computer Systems Science & Engineering2021，36，3： | 0 |
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