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| 1 | Response of blood pressure after percutaneous transluminal renal artery angioplasty and stenting显示文摘AIM: To evaluate the short and intermediate term out-come of percutaneous transluminal renal artery angioplasty (PTRA) and stenting particularly on blood pressure (BP) control and renal function and to evaluate predictors of poor BP response after successful PTRA and stenting. METHODS: We conducted a prospective analysis of all patients who underwent PTRA and stenting in our institute between August 2010 to September 2012. A total number of 86 patients were underwent PTRA and renal stenting. Selective angiography was done to confirm at least 70% angiographic stenosis. The predilatation done except few cases with critical stenosis, direct stenting was done in the rest of cases. All patients received aspirin 325 mg orally, and clopidogrel 300 mg orally within 24 h before the procedure. Heparin was used as the procedural anticoagulant agent. Optimal results with TIMI-Ⅲ flow obtained in all cases. Following stent placement, aspirin 150 mg orally once daily was continued for a minimum of 12 mo and clopidogrel 75 mg orally once daily for at least 4 wk. The clinical, radiological, electrocardiography, echocardiography and treatment data of all patients were recorded. The BP measurement, serum creatinine and glomerular filtration rate (GFR) were recorded before the procedure and 1 and 6 mo after PTRA. RESULTS: A total of 86 patients were included in the study. The mean age of study population was 55.87±11.85 years old and 67 (77.9%) of patients were male. There was a significant reduction in both systolic and diastolic BP at 1 mo after the procedure: 170.15±20.10 mmHg vs 146.60±17.32 mmHg and 98.38±10.55 mmHg vs 89.88±9.22 mmHg respectively (P=0.0000). The reduction in BP was constant throughout the follow-up period and was evident 6 mo after the procedure: 144.23±18.19 and 88.26±9.79 mmHg respectively (P=0.0000). However, no improvement in renal function was observed at any time during the follow-up period. After multivariate analysis, we found male sex, low GFR (<60 mL/min) and higher baseline mean BP as a poor predictors of successful outcome on BP response after PTRA and stenting. CONCLUSION: The PTRA and stenting can be considered as an effective therapeutic intervention for improving BP control with minimal effect on renal function. The male sex, higher baseline BP and low GFR are associated with poor BP response after successful PTRA and stenting. | Jayesh S Prajapati Sharad R Jain Hasit Joshi Shaurin Shah Kamal Sharma Sibasis Sahoo Kapil Virparia Ashok Thakkar | 2013 | World Journal of Cardiology2013，5，7： | 3 |
| 2 | Application of recombinant bovine viral diarrhea virus protein in the diagnosis of bovine viral diarrhea infection in cattle显示文摘 | Reddy J R Kwang J Kapil S | 1997 | Veterinary Microbiology1997，57，： | 1 |
| 3 | Microbial resistance to metals in the environment 显示文摘 | BRUINS MARK R SANJAY KAPIL OEHME FREDERICK W | 2000 | Ecotoxicology and Environmental Safety2000，45，： | 1 |
| 4 | Formulation develop- ment and systematic optimization of solid lipid nanoparticles of quercetin for improved brain delive' 显示文摘 | Dhawan S Kapil R Singh B | 2011 | J Pharm Pharmacol2011，63，3： | 1 |
| 5 | Signaling involved in hair follicle morphogenesis and development 显示文摘 | Pisal R Kapil D Daniel D et ol | 2014 | Mol Sci2014，15，1： | 1 |
| 6 | Formulation development and systematic optimization of solid lipid nanoparticles of QC for improved brain de- livery 显示文摘 | Dhawan S Kapil R Singh B | 2011 | J Pharm Pharmacol2011，63，3： | 1 |
| 7 | Pharmacokinetie prop- erties of combination oxyeodone plus racemic ibuprofen: two randomized, open-label, crossover studies in healthy adult volunteers显示文摘 | Kapil R Nohing A Roy P | 2004 | Clin Ther2004，26，12： | 1 |
| 8 | Pharmacokinetic prop-erties of combination oxycodone plus racemic ibuprofen:two randomized,open-label,crossover studies in healthy adult volunteers显示文摘 | Kapil R Nolting A Roy P | | 0，，12： | 1 |
| 9 | Microbial resistance to metals in the environment 显示文摘 | Bruins M R Kapil S Oehme F W | 2000 | Ecotoxicol Environ Saf2000，，45： | 1 |
| 10 | Growth of diamond thin films in a cyclic growth-etch oxy-acetylene flame process显示文摘 | Kapil R Mchta B R Vankar V D | 1998 | Thin Solid Films1998，322，： | 1 |
| 11 | Phaimacokinetic properties of combinatinon oxyeodone plus raeemic ibuprofen: two randomidzed,open label,erossovre ctudies in healthy adult volunteers 显示文摘 | Kapil R Nohing A Roy P | 2004 | Clin Ther2004，26，12： | 1 |
| 12 | Phannacokinefic properties of combination oxycodone plus racemic ibuprofen: two randomized, open-label, crossover studies in healthy aduk volunteers显示文摘 | Kapil R Nolfing A Roy P | 2004 | Clin Ther2004，26，12： | 1 |
| 13 | Serum levels of angiogenic and anti-angiogenic factors:their prognostic relevance in locally advanced hepatocellular carcinoma显示文摘 | Sharma B K Srinivasan R Kapil S | | 0，，1： | 1 |
| 14 | Microbial Resistance to Metals in the Environment显示文摘 | Bruins M R Kapil S Oehmel F W | 2000 | Ecotoxicology and Environmental Safety2000，4，： | 1 |
| 15 | Serum levels of angiogenic and anti-angiogenic factors: Their prognostic relevance in locally advanced hepatocellular carcinoma显示文摘 | Sharma BK Srinivasan R Kapil S | 2013 | Mol Cell Biochem2013，383，12： | 1 |
| 16 | Infectious bovine rhinotracheitis, parainflu- enza-3, and respiratory coronavirus 显示文摘 | Kapil S Basaraba R J | 1997 | Veterinary Clinics of North America and Food Animal Practice1997，13，： | 1 |
| 17 | Problems and limitations in thrombolysis of acute stroke patients at a tertiary care center显示文摘 | Sushma Gurav Kapil Zirpe R Wadia Manishprasad Pathak Abhijeet Deshmukh Rahul Sonawane Nikhil Goli | 2015 | Indian Journal of Critical Care Medicine2015，，： | 1 |
| 18 | Clinical and modecu-lar characteristics of nosocomial meticillin-resistant Staphylo-coccus aureus skin and soft tissue isolates from three Indianhospitals显示文摘 | Gadepalli R Dhawan B Kapil A | 2009 | J Hosp Infect2009，73，3： | 1 |
| 19 | Microbial resistance to metals in the environment显示文摘 | Brains M R Kapil S Oehme F W | 2000 | Ecotoxicology and Environmental Safety2000，45，： | 1 |
| 20 | Clinical and molecular charac- teristics of nosocomial meticill in resistant Staphylococcus aureus skin and sofl tissueisolates from three Indian hospitals 显示文摘 | Gadepalli R Dhawan B Kapil A | 2009 | J Hosp Infect2009，73，3： | 1 |
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