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| 1 | Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia显示文摘AIM To summarize the reported Middle East respiratory syndrome-coronavirus(MERS-Co V) cases, the associated clinical presentations and the outcomes. METHODS We searched the Saudi Ministry of Health website, the World Health Organization website, and the Flutracker website. We also searched MEDLINE and Pub Med for the keywords: Middle East respiratory syndromecoronavirus, MERS-Co V in combination with pediatric, children, childhood, infancy and pregnancy from the initial discovery of the virus in 2012 to 2016. The retrieved articles were also read to further find other articles. Relevant data were placed into an excel sheet and analyzed accordingly. Descriptive analytic statistics were used in the final analysis as deemed necessary.RESULTS From June 2012 to April 19, 2016, there were a total of 31 pediatric MERS-Co V cases. Of these cases 13(42%) were asymptomatic and the male to female ratio was 1.7:1. The mean age of patients was 9.8 ± 5.4 years. Twenty-five(80.6%) of the cases were reported from the Kingdom of Saudi Arabia. The most common source of infection was household contact(10 of 15 with reported source) and 5 patients acquired infection within a health care facility. Using real time reverse transcriptase polymerase chain reaction of pediatric patients revealed that 9 out of 552(1.6%) was positive in the Kingdom of Saudi Arabia. CONCLUSION Utilizing serology for MERS-CoV infection in Jordan andSaudi Arabia did not reveal any positive patients. Thus, the number of the pediatric MERS-CoV is low; the exact reason for the low prevalence of the disease in children is not known. | Jaffar A Al-Tawfiq Rana F Kattan Ziad A Memish | 2016 | World Journal of Clinical Pediatrics2016，5，4： | 8 |
| 2 | Comparison of 1,800 Laparoscopic and Open Partial Nephrectomies for Single Renal Tumors显示文摘 | Inderbir S. Gill Louis R. Kavoussi Brian R. Lane Michael L. Blute Denise Babineau J. Roberto Colombo Igor Frank Sompol Permpongkosol Christopher J. Weight Jihad H. Kaouk Michael W. Kattan Andrew C. Novick | 2007 | The Journal of Urology2007，，1： | 5 |
| 3 | 临床意义上的前列腺癌的预测标准化:可能吗?显示文摘近几十年来,对前列腺癌的生物学和流行病学的深入研究已经使前列腺癌的治疗取得了很大进展。很多前列腺癌可以在发病早期被发现,并且有多种有效的治疗手段。然而,仍无明确的数据表明这些早期诊断和治疗能够有效地控制前列腺癌的死亡率。这可能是由于接受治疗的一大部分癌症患者的恶性程度较低,即使不予治疗亦不会对患者的健康和生存期产生影响。基于过度治疗现象的存在,在当代的医疗过程中,积极监测以观后效被认为是一种有效的治疗方式。如何区别不具临床意义的肿瘤与高度恶性、高致死率的肿瘤,对为患者选择积极监测还是立即干预的治疗方案来说至关重要。本章节总结了风险分组和列线图等多种预测模型对于低度恶性肿瘤的预测能力及它们在局限性前列腺癌的治疗中所起的作用。 | Carver T Nguyen Michael W Kattan | 2012 | Asian Journal of Andrology2012，14，3： | 3 |
| 4 | Dilemma of first line regimens in metastatic pancreatic adenocarcinoma显示文摘Pancreatic cancer is one of the deadliest cancers,ranking fourth among cancer-related deaths. Despite all the major molecular advances and treatment breakthroughs, mainly targeted therapies, the cornerstone treatment of metastatic pancreatic cancer(m PC) remains cytotoxic chemotherapy. In 2016, more than 40 years after the introduction of gemcitabine in the management of m PC, the best choice for first-line treatment has not yet been fully elucidated. Two main strategies have been adopted to enhance treatment efficacy. The first strategy is based on combining non-cross resistant drugs, while the second option includes the development of newer generations of chemotherapy. More recently, two new regimens, FOLFIRINOX and gemcitabine/nab-paclitaxel(GNP), have both been shown to improve overall survival in comparison with gemcitabine alone, at the cost of increased toxicity. Therefore, the best choice for first line therapy is a matter of debate. For some authors, FOLFIRINOX should be the first choice in patients with an Eastern Cooperative Oncology Group score(0-1) given its lower hazard ratio. However, others do not share this opinion. In this paper, we review the main comparison points between FOLFIRINOX and GNP. We analyze the two pivotal trials to determine the similarities and differences in study design. In addition, we compare the toxicity profile of the two regimens as well as the impact on quality of life. Finally, we present studies revealing real life experiences and review the advantages and disadvantages of possible second-line therapies including their cost effectiveness. | Marwan Ghosn Tony Ibrahim Tarek Assi Elie El Rassy Hampig Raphael Kourie Joseph Kattan | 2016 | World Journal of Gastroenterology2016，22，46： | 2 |
| 5 | E-CADHERIN IMMUNOSTAINING OF BLADDER TRANSITIONAL CELL CARCINOMA, CARCINOMA IN SITU AND LYMPH NODE METASTASES WITH LONG-TERM FOLLOWUP显示文摘 | ROBERT R. BYRNE SHAHROKH F. SHARIAT RICHARD BROWN MICHAEL W. KATTAN RONALD A. MORTON THOMAS M. WHEELER SETH P. LERNER | 2001 | The Journal of Urology2001，，5： | 2 |
| 6 | The role of peripheral perfusion markers and lactate in septic shock resuscitation显示文摘Septic shock leads to progressive hypoperfusion and tissue hypoxia.Unfortunately,numerous uncertainties exist around the best monitoring strategy,as available techniques are mere surrogates for these phenomena.Never-theless,central venous oxygen saturation(ScvO 2),venous-to-arterial CO 2 gap,and lactate normalization have been fostered as resuscitation targets for septic shock.Moreover,recent evidence has challenged the central role of lactate.Following the ANDROMEDA-SHOCK trial,capillary refill time(CRT)has become a promissory target,considering the observed benefits in mortality,treatment intensity,and organ dysfunction.Interpretation of CRT within a multimodal approach may aid clinicians in guiding resuscitative interventions and stop resuscitation earlier,thus avoiding the risk of morbid fluid overload.Integrative assessment of a patient’s perfusion status can be easily performed using bedside clinical tools.Based on its fast kinetics and recent supporting evidence,targeting CRT(within a holistic assessment of perfusion)may improve outcomes in septic shock resuscitation. | Eduardo Kattan Glenn Hernández | 2022 | Journal of Intensive Medicine2022，2，1： | 2 |
| 7 | Dissemination of Acinetobacter baumannii clones with OXA-23 Carbapenemase in Colombian hospitals显示文摘 | Villegas MV Kattan JN Correa A | 2007 | Antimicrob Agents Chemother2007，51，6： | 1 |
| 8 | Dissemination of Acinetobacter baumannii clones with OXA-23 carbapenemase in Colombian Hospitals显示文摘 | Villegas MV Kattan JN Correa A | 2007 | Antimicrob Agents Chemother2007，51，6： | 1 |
| 9 | The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma显示文摘 | Rosenstreich DL Eggleston P Kattan M | 1997 | N Engl J Med1997，336，： | 1 |
| 10 | A preoperative nomogram for disease recurrence following radical prostatectomy for prostate cancer显示文摘 | Kattan M W Eastham J A Stapleton A M | 1998 | J Natl Cancer Inst1998，90，10： | 1 |
| 11 | Doctor, what are my chances of having a positive sentinel node? A validated nomogrant for risk estimation 显示文摘 | Bevilacqua JL Kattan MW Fey JV | 2007 | J Clin Oncol2007，25，24： | 1 |
| 12 | A preoperative nomogram for disease recurrence following radical prostatectomy for prostate cancer显示文摘 | Kattan MW Eastham JA Stapleton AM | 1998 | J Natl Cancer Inst1998，90，10： | 1 |
| 13 | Role of manganese superoxide dismutase on growth and invasive properties of human estrogen- independent breast cancer cells显示文摘 | Kattan Z Minig V Leroy P | 2008 | Breast Cancer Res Treat2008，108，20： | 1 |
| 14 | Nomograms for predict-ing graft function and survival in living donor kidney transplantation based on the UNOS Registry显示文摘 | Tiong HY Goldfarb DA Kattan MW | 2009 | J Urol2009，181，3： | 1 |
| 15 | The inpact of internal spermatic artery ligation during laparoscopic varicocelectomy on recurrence tate and short post operative outcome显示文摘 | Said Kattan | 2001 | Scand J Urol Nephrol2001，35，3： | 1 |
| 16 | Folfox-6 combination as the first-line treatment of locally advanced and/or metastatic pancreatic cancer显示文摘 | Ghosn M Farhat F Kattan J | 2007 | Am J Clin Oncol2007，30，1： | 1 |
| 17 | Postoperative nomogram for 12 - year sarcoma - specific death 显示文摘 | Kattan MW Leung DH Brennan MF | 2002 | J Clin Oncol2002，20，3： | 1 |
| 18 | Prediction of two-phasepressure gradients of refrigerants in horizontal tubes显示文摘 | Ould Didi M B Kattan N Thome J R | 2002 | International Journal of Refrigeration2002，25，7： | 1 |
| 19 | Re: Updated nomogram to predict pathologic stage of prostate cancer given prostate--specific antigen level, clinical stage, and biopsy gleason score (Partin Tables) based on cases from 2000 to 2005显示文摘 | Kattan MW | 2007 | Eur Urol2007，52，5： | 1 |
| 20 | Doctor, what are my chances of having a positive sentinel node? A validated nomogram for risk estimation 显示文摘 | Bevilaequa JL Kattan MW Fey JV | 2007 | J Clin Oncol2007，25，24： | 1 |
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