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| 1 | Current surgical management of pancreatic endocrine tumor liver metastases显示文摘BACKGROUND: The management of metastatic disease in pancreatic endocrine tumors (PETs) demands a multidisciplinary approach and the cooperation of several medical specialties. The role of surgery is critical, even when a radical excision cannot always be achieved. DATA SOURCES: A PubMed search of relevant articles published up to February 2011 was performed to identify current information about PET liver metastases regarding diagnosis and management, with an emphasis on surgery. RESULTS: The early diagnosis of metastases and their accurate localization, most commonly in the liver, is very important. Surgical options include radical excision, and palliative excision to relieve symptoms in case of failure of medical treatment. The goal of the radical excision is to remove the primary tumor bulk and all liver metastases at the same time, but unfortunately it is not feasible in most cases. Palliative excisions include aggressive tumor debulking surgeries in well-differentiated carcinomas, trying to remove at least 90% of the tumor mass, combined with other additional destructive techniques such as hepatic artery embolization or chemoembolization to treat metastases or chemoembolization to relieve symptoms in cases of rapidly growing tumors. The combination of chemoembolization and systemic chemotherapy results in better response and survival rates. Other local destructive techniques include ethanol injection, cryotherapy and radiofrequency ablation. CONCLUSION: It seems that the current management of PETs can achieve important improvements, even in advanced cases. | Theodoros E Pavlidis Kyriakos Psarras Nikolaos G Symeonidis Efstathios T Pavlidis Athanasios K Sakantamis | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 5 |
| 2 | Absolute reaction rate of chlorine atoms with chloroiodomethane显示文摘 | KYRIAKOS G DIMITRIS Y A | 1999 | J Phys Chem A1999，103，： | 1 |
| 3 | Focal hematopoietic hyperplasia of thefib-a form of pseudotumor显示文摘 | Edelstein G Kyriakos M | 1984 | Skeletal Radiol1984，11，2： | 1 |
| 4 | The Bright Side and Dark Side of Embedded Ties in Busi- ness-to-business Innovation 显示文摘 | Noordhoff C S Kyriakos K Christine M Pieter P Benedict G C D | 2011 | Journal of Marketing2011，75，5： | 1 |
| 5 | Indications for the surgical management of pancreatic trauma: An update显示文摘Pancreatic trauma is rare compared to other abdominal solid organ injuries,accounting for 0.2%-0.3% of all trauma patients. Moreover, this type of injury may frequently be overlooked or not readily appreciated on initial clinical examinations and investigations. The organ injury scale determines the severity of the trauma. Nonetheless, there are conflicting recommendations for the best strategy in severe cases. Overall, conservative management of induced severe traumatic pancreatitis is adequate. Modern imaging modalities such as ultrasound scanning and computed tomography scanning can detect injuries in fewer than 60% of patients. However, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography(ERCP) have diagnostic accuracies approaching 90%-100%. Thus, management options include ERCP and stent placement or distal pancreatectomy in cases of complete gland transection and wide drainage only for damage control surgery, which can prevent mortality but increases the risk of morbidity. In the majority of cases, surgical intervention is not required and should be reserved for only severe grade Ⅲ to grade Ⅴ injuries. | Efstathios Theodoros Pavlidis Kyriakos Psarras Nikolaos G Symeonidis Georgios Geropoulos Theodoros Efstathios Pavlidis | 2022 | World Journal of Gastrointestinal Surgery2022，14，6： | 1 |
| 6 | STOLAS:Switching Technologies for Optically Labeled Signals显示文摘 | Kyriakos G Vlachos Idelfonso T Monroy Koonen A M J | 2003 | IEEE Optical Communications2003，915，： | 1 |
| 7 | Effect of ionizing radiation on physicochemical and mechanical properties of coral monolayer and multilayer semirigid plastics packaging materials显示文摘 | ANTONIOS E G KYRIAKOS A R MICHAEL G K | 2004 | Radiation Physics and Chemistry2004，69，： | 1 |
| 8 | Effect of Ionizing Radiation on Physicochemical and Mechanical Properties of Commercial Monolayer and Multilayer Semi Rigid Plastics Packaging Materials显示文摘 | ANTONIOS E G KYRIAKOS A R MICHAEL G K | 2004 | Radiation Physics and Chemistry2004，69，5： | 1 |
| 9 | Multi-player non-zero- sum games: Online adaptive learning solution of coupled Hamilton-Jacobi equations 显示文摘 | KYRIAKOS G V FRANK L L | 2011 | Automatica2011，47，： | 1 |
| 10 | COVID-19 and liver injury in individuals with obesity显示文摘Coronavirus disease 2019 is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 that manifests as a variety of clinical manifestations,including liver damage commonly detected by a hepatocellular pattern from liver function tests.Liver injury is associated with a worse prognosis overall.Conditions associated with the severity of the disease include obesity and cardiometabolic comorbidities,which are also associated with nonalcoholic fatty liver disease(NAFLD).The presence of NAFLD,similarly to obesity,is associated with an unfavourable impact on the coronavirus disease 2019 outcome.Individuals with these conditions could present with liver damage and elevated liver function tests due to direct viral cytotoxicity,systemic inflammation,ischemic or hypoxic liver damage or drug side effects.However,liver damage in the setting of NAFLD could also be attributed to a pre-existing chronic low-grade inflammation associated with surplus and dysfunctional adipose tissue in these individuals.Here we investigate the hypothesis that a pre-existing inflammatory status is exacerbated after severe acute respiratory syndrome coronavirus 2 infection,which embodies a second hit to the underestimated liver damage. | Ioannis G Lempesis Eleni Karlafti Petros Papalexis George Fotakopoulos Kyriakos Tarantinos Vasileios Lekakis Stavros P Papadakos Evangelos Cholongitas Vasiliki E Georgakopoulou | 2023 | World Journal of Gastroenterology2023，29，6： | 0 |
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