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29篇 您的检索式:作者名="Kang SL"
    题名 作者 年代 出处 被引量
1Emerging role of Hippo pathway in gastric and othergastrointestinal cancers显示文摘More evidence has underscored the importance of Hippo signaling pathway in gastrointestinal tissue homeostasis, whereas its deregulation induces tumorigenesis. Yes-associated protein 1(YAP1) and its close paralog TAZ, transcriptional co-activator with a PDZbinding motif, function as key effectors negatively controlled by the Hippo pathway. YAP1/TAZ exerts oncogenic activities by transcriptional regulation via physical interaction with TEAD transcription factors. In various cancers, Hippo pathway cross-talks with pro- or anti-tumorigenic pathways such as GPCR, Wnt/β-catenin, Notch and TGF-β signaling and is deregulated by multiple factors including cell density/junction and micro RNAs. As YAP1 expression is significantly associated with poor prognosis of gastric and other gastrointestinal cancers, detailed delineation of Hippo regulation in tumorigenesis provides novel insight for therapeutic intervention. In current review, we summarized the recent research progresses on the deregulation of Hippo pathway in the gastrointestinal tract including stomach and discuss the molecular consequences leading to tumorigenesis.Wei Kang Alfred SL Cheng Jun Yu Ka Fai To 2016World Journal of Gastroenterology2016,22,3:11
2Effect of Alley Cropping with Leucaena Leucocephala an Fertilizer Application on Yield of Vegetable Crops显示文摘PALADA MC KANG BT CLASSEN SL 1992Agroforstry Systems1992,,19:1
3Activation of the suceinate receptor hGPR91 in maeula clensa cells causes renin release显示文摘Vargas SL Toma I Kang JJ 2009J Am Soc Nephrol2009,20,5:1
4Activation of the succinate receptor GPR91 in macula densa cells causes renin release显示文摘Vargas SL Toma I Kang JJ 0,,05:1
5Activation of the succinate receptor GPR91 in macula densa cells causes renin release显示文摘Vargas SL Toma I Kang JJ 0,,5:1
6Vesicular gold assemblies based on host-guest inclusion and its controllable release of Doxorubicin 显示文摘Ha W Kang Y Peng SL Ding LS Zhang S Li BJ 2013Nanotechnology2013,24,49:1
7Prospective evaluation of the effect of an aminoglycoside dosing regimen on rates of observed nephrotoxicity and ototoxicity 显示文摘Rybak Mj Abate B J Kang SL 1999Antimicrob Agents Chemother1999,43,:1
8Transanal total mesorectal excision assisted by single-port laparoscopic surgery for low rectal cancer显示文摘Chert WH Kang L Luo SL 2015Tech Coloproctol2015,19,9:1
9Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice显示文摘Lee TH Kim SU Yu SL Kim SH Park DS Moon HB Dho SH Kwon KS Kwon HJ Han YH Jeong S Kang SW ShinHS Lee KK Rhee SG Yu DY 2003Blood2003,101,12:1
10Coassembly of inorganic mac- romolecule of exfoliated LDH nanosheets with cellulose 显示文摘Kang HL Huang GL Ma SL 2009J Phys Chem C2009,113,21:1
11Prospective evalu- ation of the elect of an aminoglycoside dosing regimen on rates of observed nephrotoxicity and ototoxicity显示文摘Rybak MJ Abate BJ Kang SL 1999Anti- microb Agents Chemother1999,43,7:1
12Evaluation of salivary aspiration inbrain-injured patients with tracheostomy 显示文摘Kang Y Chun MH Lee SL 2013Ann Rehabil Med2013,37,1:1
13Transanal total mesorectal exci-sion for rectal cancer: a preliminary report 显示文摘Kang L Chen WH Luo SL 2015Surg Endosc2015,,:1
14Transanal total mesorectal exci-sion assisted by single-port laparoscopic surgery for low rectal canc-er显示文摘Chen WH Kang L Luo SL 2015Tech Coloproctol2015,19,9:1
15Transanal Total Mesorectal Excision :Will It Be a Valid Alternative in Rectal Cancer Surgery? 显示文摘Chen WH Luo SL Kang L 2015AnnSurg2015,,:1
16Experimental Evaluation of Toughe-ning Mechanism s in A Ium ina Zirconia Composites 显示文摘Shin YS Rhee YW Kang SL 1999Am Ceram Soc1999,82,5:1
17Transanal total mesorectal ex- cision assisted by single-port laparoscopic surgery for low rec- tal cancer显示文摘Chen WH Kang L Luo SL 2015Tech Coloproctol2015,19,9:1
18Enantioselective synthesis of (3- indolyl) glycine derivatives via asymmetric Friedel-Crafts reaction between indotes and glyoxylate imines显示文摘Kang Q Zhao ZA You SL 2009Tetrahedron2009,65,8:1
19Prospective evaluation of the effect of an aminoglycoside dosing regimen on rates of observed nephrotoxicity and ototoxicity显示文摘 Abate BJ Kang SL 1999Antimicrob Agents Chemother1999,43,7:1
20Prospective evaluation of the effect of an aminoglycoside dosing regimen on rates of observed nephrotoxicity and ototoxicity 显示文摘Rybak MJ Abate BJ Kang SL 1999Antimicrob Agents Chemother1999,43,:1
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