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| 1 | EGF promoter SNPs, plasma EGF levels and risk of breast cancer in Chinese women显示文摘 | Wang, Y. | 2008 | 南京医科大学学报(自然科学版)2008，28，12： | 32 |
| 2 | Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients显示文摘Human infection with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)causes coronavirus disease 2019(COVID-19)and there is no cure currently.The 3CL protease(3CLpro)is a highly conserved protease which is indispensable for CoVs replication,and is a promising target for development of broad-spectrum antiviral drugs.In this study we investigated the anti-SARS-CoV-2 potential of Shuanghuanglian preparation,a Chinese traditional patent medicine with a long history for treating respiratory tract infection in China.We showed that either the oral liquid of Shuanghuanglian,the lyophilized powder of Shuanghuanglian for injection or their bioactive components dose-dependently inhibited SARS-CoV-23CLpro as well as the replication of SARS-CoV-2 in Vero E6 cells.Baicalin and baicalein,two ingredients of Shuanghuanglian,were characterized as the first noncovalent,nonpeptidomimetic inhibitors of SARS-CoV-23CLpro and exhibited potent antiviral activities in a cell-based system.Remarkably,the binding mode of baicalein with SARS-CoV-23CLpro determined by X-ray protein crystallography was distinctly different from those of known 3CLpro inhibitors.Baicalein was productively ensconced in the core of the substrate-binding pocket by interacting with two catalytic residues,the crucial S1/S2 subsites and the oxyanion loop,acting as a“shield”in front of the catalytic dyad to effectively prevent substrate access to the catalytic dyad within the active site.Overall,this study provides an example for exploring the in vitro potency of Chinese traditional patent medicines and effectively identifying bioactive ingredients toward a specific target,and gains evidence supporting the in vivo studies of Shuanghuanglian oral liquid as well as two natural products for COVID-19 treatment. | Hai-xia Su Sheng Yao Wen-feng Zhao Min-jun Li Jia Liu Wei-juan Shang Hang Xie Chang-qiang Ke Hang-chen Hu Mei-na Gao Kun-qian Yu Hong Liu Jing-shan Shen Wei Tang Lei-ke Zhang Geng-fu Xiao Li Ni Dao-wen Wang Jian-ping Zuo Hua-liang Jiang Fang Bai Yan Wu Yang Ye Ye-chun Xu | 2020 | Acta Pharmacologica Sinica2020，41，9： | 32 |
| 3 | Prevalence and risk factors of fatty liver disease in Chengdu,Southwest China显示文摘BACKGROUND:Fatty liver disease(FLD)is increasingly recognized as one of the most common chronic liver diseases in China.This study aimed to investigate the prevalence and risk factors of FLD in Chengdu,Southwest China,and to provide a relevant basis for the prevention and intervention of FLD. METHODS:Altogether 9094 subjects(4721 men and 4373 women)of over 18 years old who had received a medical checkup in the West China Hospital of Sichuan University between January and December 2007 were evaluated for FLD.FLD was diagnosed by ultrasonography.Body mass index(BMI),height,body weight,blood pressure,fasting plasma glucose(FPG),triglycerides(TG),total cholesterol (TCh),alanine aminotransferase(ALT),hepatitis B surface antigen(HBsAg),high-density lipoprotein cholesterol (HDL-C),and low-density lipoprotein cholesterol(LDL-C) were measured using routine laboratory methods. RESULTS:The overall prevalence of FLD was 12.5%,which was more than 3-fold higher in males than in females (18.9%vs.5.7%,χ2=359.624,P<0.001).The prevalence increased with age in females and males of less than 50 years.The prevalence of alcoholic,suspected alcoholic,and non-alcoholic FLD was 2.6%,3.6%,and 6.3%,respectively. Multiple logistic regression analyses showed that 10 factors (male sex,age,BMI,FPG,hypertension,TG,TCh,HDL-C, LDL-C,and ALT abnormalities)were closely related to FLD. In heavy drinkers,obesity increased the risk of FLD by 23.78-fold(95%CI,10.22-55.33),but heavy drinking was only associated with a 2-fold(95%CI,1.50-2.66)increased risk in obese subjects.CONCLUSIONS:The prevalence of FLD among a health- checkup population in Chengdu,Southwest China was lower than the published for other areas of China.FLD in Chengdu adults was found to be closely associated with sex, age,BMI,and other metabolic syndrome features. | Li, Hong Wang, You-Juan Tan, Ke Zeng, Li Liu, Li Liu, Feng-Jun Zhou, Tao-You Chen, En-Qiang Tang, Hong | 2009 | Hepatobiliary & Pancreatic Diseases International2009，8，4： | 22 |
| 4 | Mouse miRNA-709 directly regulates miRNA-15a/16-1 biogenesis at the posttranscriptional level in the nucleus: evidence for a microRNA hierarchy system显示文摘MicroRNAs (miRNAs ) 是内长的 noncoding RNA (~ 22 nt ) 在细胞质在 post-transcriptional 水平调整目标基因表示。在房间原子核的要求功能的 argonaute 家庭蛋白质提示了我们假设那 miRNAs 的 miRNAs 和 miRNA 的存在的最近的发现可以也在房间原子核有规章的功能。在这研究,我们证明老鼠 miR-709 主要位于各种各样的房间类型的原子核并且它的原子本地化模式很快在 apoptotic 刺激之上变化。在房间原子核, miR-709 直接在 pri-miR-15a/16-1 上绑在一个 19-nt miR-709 识别元素并且阻止它处理成 pre-miR-15a/16-1,导致 miR-15a/16-1 成熟的抑制。而且,原子 miR-709 通过 miR-15a/16-1 小径参予房间 apoptosis 的规定。在摘要,现在的学习提供一 miRNA 能由直接在原子核指向他们的主要抄本控制另外的 miRNAs 的生物的续生说的第一条证据。 | Rui Tang Limin Li Dihan Zhu Dongxia Hou Ting Cao Hongwei Gu Jing Zhang Junyuan Chen Chen-Yu Zhang Ke Zen | 2012 | Cell Research2012，22，3： | 23 |
| 5 | Combined subfascial endoscopic perforator surgery and endovenous laser treatment without impact on the great saphenous vein for management of lower-extremity varicose veins显示文摘 | GAN Shu-jie QIAN Shui-xian ZHANG Ci MAO Jie-qi LI Ke TANG Jing-dong | 2013 | Chinese Medical Journal2013，，3： | 18 |
| 6 | Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles显示文摘颠倒使人重新住入肿瘤的房间(TRC ) 的药抵抗或起源的发展中的新奇途径像房间的癌症房间是迫切临床的需要改进癌症病人的结果。这里,我们显示出用肿瘤颠倒 TRC 的药抵抗的一条创新途径包含反肿瘤药的导出房间的 microparticles (T-MPs ) 。由比区分的癌症房间更可变形的优点, TRC 优先地收起 T-MPs 在进入房间以后释放反肿瘤药,它接着导致 TRC 的死亡。内在的机制包括防碍药流出并且支持这些药的原子入口。我们的调查结果在用有希望的临床的应用程序颠倒 TRC 的药抵抗在 T-MPs 的举起和一条新奇途径的有效性表明肿瘤房间柔软的重要性。 | Jingwei Ma Yi Zhang Ke Tang Huafeng Zhang Xiaonan Yin Yong Li Pingwei Xu Yanling Sun Ruihua Ma Tiantian Ji Junwei Chen Shuang Zhang Tianzhen Zhang Shunqun Luo Yang Jin Xiuli Luo Chengyin Li Hongwei Gong Zhixiong Long Jinzhi Lu Zhuowei Hu Xuetao Cao Ning Wang Xiangliang Yang Bo Huang | 2016 | Cell Research2016，26，6： | 17 |
| 7 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 8 | Parthenolide protects human lens epithelial cells from oxidative stress-induced apoptosis via inhibition of activation of caspase-3 and caspase-9显示文摘透镜的 apoptosis 上皮的房间作为奔流形成的普通基础被建议了,与是的氧化应力主要原因。这研究被执行对人的透镜的导致 oxidativestress 的 apoptosis 调查草药的成分 parthenolide 的保护的效果上皮(HLE ) 房间和可能的分子的机制包含了。HLE 房间(SRA01-04 ) 在 parthenolide (10, 20 和 50 microM ) 的不同剂量的缺席或存在与 50 microM H (2 ) O (2 ) 被孵化。到学习 apoptosis,房间被词法检查和 Annexin V-propidium 碘化物估计两倍染色的流动 cytometry;调查内在的分子的机制, caspase-3 和 caspase-9 的表示旁边是 assayed 西方的污点和量的 RT-PCR,和 caspase-3 和 caspase-9 的活动我们由 Chemicon caspase 的 remeasured 比色的活动试金工具包。为 18 h 与 H (2 ) O (2 ) 刺激了,, HLE 房间的高部分面对不同集中的 parthenolide 经历了 apoptosis, HLE 房间 apoptosis 堵住的剂量依赖者被观察。H (2 ) O (2 ) 在 HLE 房间导致的表示 ofcaspase-3 和 caspase-9 被 parthenolideboth 显著地在蛋白质和信使 rna 层次减少,并且 caspase-3 和 caspase-9 的激活被 parthenolide 也以一种剂量依赖者方式压制。在结论, parthenolide 通过 caspase-3 andcaspase-9 的激活的抑制阻止 HLEcells 氧化导致压力的 apoptosis,建议对奔流形成的潜在的保护的效果。 | Hangping Yao Xiajing Tang Xueting Shao Lei Feng Nanping Wu Ke Yao | 2007 | Cell Research2007，17，6： | 16 |
| 9 | Identification of mouse liver mitochondria-associated miRNAs and their potential biological functions显示文摘 | Zhen Bian Li-Min Li Rui Tang Dong-Xia Hou Xi Chen Chen-Yu Zhang Ke Zen | 2010 | Cell Research2010，20，9： | 15 |
| 10 | Risk factors analysis of postoperative intracranial infection in patients with recurrent glioma显示文摘To the editor:Neuroglioma is the most common neoplasm of central nervous system,which has particular clinical characteristics and prognosis after therapy.Combined modality therapy involving surgery,radiotherapy,and chemotherapy is considered the efficacious method currently to treating such disease.1 However,the recurrence of the lesion is still inevitable,of which the surgical removal is essential for prolonging survival time of patients. | TANG Ke ZHOU Jing-an | 2013 | Chinese Medical Journal2013，，9： | 14 |
| 11 | Estimating the crop leaf area index using hyperspectral remote sensing显示文摘The leaf area index(LAI) is an important vegetation parameter,which is used widely in many applications.Remote sensing techniques are known to be effective but inexpensive methods for estimating the LAI of crop canopies.During the last two decades,hyperspectral remote sensing has been employed increasingly for crop LAI estimation,which requires unique technical procedures compared with conventional multispectral data,such as denoising and dimension reduction.Thus,we provide a comprehensive and intensive overview of crop LAI estimation based on hyperspectral remote sensing techniques.First,we compare hyperspectral data and multispectral data by highlighting their potential and limitations in LAI estimation.Second,we categorize the approaches used for crop LAI estimation based on hyperspectral data into three types:approaches based on statistical models,physical models(i.e.,canopy reflectance models),and hybrid inversions.We summarize and evaluate the theoretical basis and different methods employed by these approaches(e.g.,the characteristic parameters of LAI,regression methods for constructing statistical predictive models,commonly applied physical models,and inversion strategies for physical models).Thus,numerous models and inversion strategies are organized in a clear conceptual framework.Moreover,we highlight the technical difficulties that may hinder crop LAI estimation,such as the 'curse of dimensionality' and the ill-posed problem.Finally,we discuss the prospects for future research based on the previous studies described in this review. | LIU Ke ZHOU Qing-bo WU Wen-bin XIA Tian TANG Hua-jun | 2016 | Journal of Integrative Agriculture2016，15，2： | 14 |
| 12 | Accurate and broadband manipulations of harmonic amplitudes and phases to reach 256 QAM millimeter-wave wireless communications by time-domain digital coding metasurface显示文摘We propose a theoretical mechanism and new coding strategy to realize extremely accurate manipulations of nonlinear electromagnetic harmonics in ultrawide frequency band based on a time-domain digital coding metasurface(TDCM).Using the proposed mechanism and coding strategy,we design and fabricate a millimeter-wave(mmWave) TDCM,which is composed of reprogrammable meta-atoms embedded with positive-intrinsic-negative diodes.By controlling the duty ratios and time delays of the digital coding sequences loaded on a TDCM,experimental results show that both amplitudes and phases of different harmonics can be engineered at will simultaneously and precisely in broad frequency band from 22 to33 GHz,even when the coding states are imperfect,which is in good agreement with theoretical calculations.Based on the fabricated high-performance TDCM,we further propose and experimentally realize a large-capacity mmWave wireless communication system,where 256 quadrature amplitude modulation,along with other schemes,is demonstrated.The new wireless communication system has a much simpler architecture than the currently used mmWave wireless systems,and hence can significantly reduce the hardware cost.We believe that the proposed method and system architecture can find vast application in future mmWave and terahertz-wave wireless communication and radar systems. | Ming Zheng Chen Wankai Tang Jun Yan Dai Jun Chen Ke Lei Zhang Cheng Zhang Jin Yang Lianlin Li Qiang Cheng Shi Jin Tie Jun Cui | 2022 | National Science Review2022，9，1： | 13 |
| 13 | Molecular Typing of Brucella Suis Collected from 1960s to 2010s in China by MLVA and PFGE显示文摘Brucellosis is a bacterial anthropozoonosis usually caused by Brucella abortus, Brucella melitensis, Brucella suis and Brucella canis. Brucella suis, the causative agent of swine brucellosis, is classified into five biovars and preferentially infects different animal hosts [1] . | LI Zhen Jun CUI Bu Yun CHEN Hai CHEN Jing Diao ZHAO Hong Yan PIAO Dong Ri JIANG Hai ZHANG Li TANG Xu KE Chang Wen YAO zhen TIAN Guo Zhong | 2013 | Biomedical and Environmental Sciences2013，26，6： | 13 |
| 14 | Molecular Typing of Leptospira interrogans Strains Isolated from Rattus tanezumi in Guizhou Province,Southwest of China显示文摘Objective To identify and type three leptospires isolated from Rattus tanezumi in Guizhou Province by using three molecular techniques (PFGE, MLVA, and MLST), reveal the molecular characteristic of causative agents of local leptospirosis and evaluate these three molecular methods based on their detection resolution and efficiency. Methods Three Leptospira strains were isolated from the kidney of Rattus tanezumi and cultured with EMJH medium. PFGE, MLVA, and MLST assays were applied to type the three strains isolated from Rattus tanezumi in Guizhou Province. Results PFGE, MLVA, and MLST typing showed that the three leptospiral isolates matched with leptospiral serogroup Icterohaemorrhagiae serovar Lai. The findings of the genotyping methods were consistent. MLVA and MLST defined genotypes, whereas PFGE allowed the recognition of additional subgroups within the genotypes, and the findings of molecular typing were also consistent with those of traditional techniques. Conclusion Three leptospiral isolates from Guizhou Province matched with leptospiral serogroup Icterohaemorrhagiae serovar Lai, and PFGE, MLVA, and MLST, as reliable molecular techniques for identifying and typing of Leptospira interrogans, would contribute to the active surveillance, outbreak investigation and source tracking for leptospirosis in Guizhou Province. | LI Shi Jun ZHANG Cui Cai LI Xiu Wen TIAN Ke Cheng TANG Guang Peng WANG Ding Ming LIU Ying NIE Yi Xin JIANG Xiu Gao | 2012 | Biomedical and Environmental Sciences2012，25，5： | 12 |
| 15 | Diagnostic accuracy of transient elastography (Fibro Scan) in detection of esophageal varices in patients with cirrhosis: A meta-analysis显示文摘AIM To investigate the diagnostic accuracy of Fibro Scan(FS) in detecting esophageal varices(EV) in cirrhotic patients.METHODS Through a systemic literature search of multiple databases, we reviewed 15 studies using endoscopy as a reference standard, with the data necessary to calculate pooled sensitivity(SEN) and specificity(SPE), positive and negative LR, diagnostic odds ratio(DOR) and area under receiver operating characteristics(AUROC). The quality of the studies was rated by the Quality Assessment of Diagnostic Accuracy studies-2 tool. Clinical utility of FS for EV was evaluated by a Fagan plot. Heterogeneity was explored using meta-regression and subgroup analysis. All statistical analyses were conducted via Stata12.0, MetaD isc1.4 and RevM an5.RESULTS In 15 studies(n = 2697), FS detected the presence of EV with the summary sensitivities of 84%(95%CI: 81.0%-86.0%), specificities of 62%(95%CI: 58.0%-66.0%), a positive LR of 2.3(95%CI: 1.81-2.94), a negative LR of 0.26(95%CI: 0.19-0.35), a DOR of 9.33(95%CI: 5.84-14.92) and an AUROC of 0.8262. FS diagnosed the presence of large EV with the pooled SEN of 0.78(95%CI: 75.0%-81.0%), SPE of 0.76(95%CI: 73.0%-78.0%), a positive and negative LR of 3.03(95%CI: 2.38-3.86) and 0.30(95%CI: 0.23-0.39) respectively, a summary diagnostic OR of 10.69(95%CI: 6.81-16.78), and an AUROC of 0.8321. A meta-regression and subgroup analysis indicated different etiology could serve as a potential source of heterogeneity in the diagnosis of the presence of EV group. A Deek's funnel plot suggested a low probability for publication bias.CONCLUSION Using FS to measure liver stiffness cannot provide high accuracy for the size of EV due to the various cutoff and different etiologies. These limitations preclude widespread use in clinical practice at this time; therefore, the results should be interpreted cautiously given its SEN and SPE. | Ke Pu Jing-Hong Shi Xu Wang Qian Tang Xin-Jie Wang Kai-Lin Tang Zhong-Qi Long Xing-Sheng Hu | 2017 | World Journal of Gastroenterology2017，23，2： | 12 |
| 16 | Synthesis and curing of a novel amino-containing phthalonitrile derivative显示文摘A novel phthalonitrile derivative containing an amino group, 3,5-bis(3,4-dicyanophenoxy)aniline (CPA), was synthesized via a nucleophilic displacement of 4-nitrophthalonitrile and 5-aminoresorcinol hydrochloride. The structure of CPA was confirmed by Fourier transform infrared spectra (FT-IR) and nuclear magnetic resonance (1H NMR). Thermal analysis performed on CPA revealed that the novel phthalonitrile derivative showed a self-promotion curing behavior and the resulting polymer exhibited outstanding heat-resistance. | Ke Zeng Ke Zhou Wen Rui Tang Yan Tang Hong Fei Zhou Tao Liu Yi Peng Wang Hai Bing Zhou Gang Yang | 2007 | Chinese Chemical Letters2007，18，5： | 12 |
| 17 | Highly selective catalytic reduction of NO_x by MnO_x–CeO_2–Al_2O_3 catalysts prepared by self-propagating high-temperature synthesis显示文摘We first present preparation of MnOx–CeO_2–Al_2O_3 catalysts with varying Mn contents through a self-propagating high-temperature synthesis(SHS) method, and studied the application of these catalysts to the selective catalytic reduction of NOxwith NH3(NH_3-SCR).Using the catalyst with 18 wt.% Mn(18 MnCe1Al2), 100% NO conversion was achieved at 200°C and a gas hourly space velocity of 15384 hr-1, and the high-efficiency SCR temperature window, where NO conversion is greater than 90%, was widened to a temperature range of 150–300°C. 18 MnCe1Al2 showed great resistance to SO_2(100 ppm)and H_2O(5%) at 200°C. The catalysts were characterized using X-ray diffraction, X-ray photoelectron spectroscopy, Brunauer–Emmett–Teller(BET) analysis, scanning electron microscopy, Fourier transform infrared spectroscopy, and H_2 temperature programmed reduction. The characterization results showed that the surface atomic concentration of Mn increased with increasing Mn content, which led to synergism between Mn and Ce and improved the activity in the SCR reaction. 18 MnCe1Al2 has an extensive pore structure,with a BET surface area of approximately 135.4 m^2/g, a pore volume of approximately 0.16 cm^3/g, and an average pore diameter of approximately 4.6 nm. The SCR reaction on 18 MnCe1Al2 mainly followed the Eley-Rideal mechanism. The performances of the MnOx–CeO_2–Al_2O_3 catalysts were good, and because of the simplicity of the preparation process,the SHS method is applicable to their industrial-scale manufacture. | Chao Wang Feng Yu Mingyuan Zhu Changjin Tang Ke Zhang Dan Zhao Lin Dong Bin Dai | 2019 | Journal of Environmental Sciences2019，31，1： | 11 |
| 18 | Identification of aberrant cell cycle regulation in Epstein-Barr virus-associated nasopharyngeal carcinoma by cDNA microarray and gene set enrichment analysis显示文摘 | Wenling Zhang Zhaoyang Zeng Yanhong Zhou Wei Xiong Songqing Fan Lan Xiao Donghai Huang Zheng Li Dan Li Minghua Wu Xiaoling Li Shourong Shen Rong Wang Li Cao Ke Tang Guiyuan Li | 2009 | Acta Biochimica et Biophysica Sinica2009，41，5： | 11 |
| 19 | Investigation of migration of pollutant at the base of Suzhou Qizishan landfill without a liner system显示文摘在它被操作 13 年了以后,我们在苏州垃圾堆的底调查了污染物质的移植。调查被在从淤泥的泥土存款拿的土壤样品上执行化学分析执行。氯化物,化学需氧量(货到付款) 和在土壤样品的重金属的集中用标准方法被决定。实验数据证明氯化物的最大的迁居深度是超过 10 m,当货到付款的最大的迁居深度在 1 和 3.5 m 之间变化了时。差别处于散开率和 leachate 土壤相互作用被归因于变化,这被相信。氯化物侧面也显示移流可以是在这个地点的主导的沾染物运输机制。Cu, Pb 和 Cr 的全部的内容主要离背景层次和这些金属的集中价值很靠近比中国土壤质量标准和欧洲标准指定的起点值低。在淤泥的泥土的表面的货到付款的水可引出的集中通常超过中国标准指定的极限值。毛孔水里的铜和铬的集中是 1 个 ∼2 数量级不到在土壤以内的这些重金属的全部的集中,暗示重金属是主要由土壤粒子吸附了。最后,补习方法为这个垃圾堆地点被建议。 | Hai-jian XIE | 2009 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2009，10，3： | 11 |
| 20 | Investigating the Transport Mechanism of PM2.5 Pollution during January 2014 in Wuhan, Central China显示文摘Severe haze pollution that occurred in January 2014 in Wuhan was investigated. The factors leading to Wuhan’s PM2.5 pollution and the characteristics and formation mechanism were found to be significantly different from other megacities, like Beijing. Both the growth rates and decline rates of PM2.5 concentrations in Wuhan were lower than those in Beijing, but the monthly PM2.5 value was approximately twice that in Beijing. Furthermore, the sharp increases of PM2.5 concentrations were often accompanied by strong winds. A high-precision modeling system with an online source-tagged method was established to explore the formation mechanism of five haze episodes. The long-range transport of the polluted air masses from the North China Plain (NCP) was the main factor leading to the sharp increases of PM2.5 concentrations in Wuhan, which contributed 53.4% of the monthly PM2.5 concentrations and 38.5% of polluted days. Furthermore, the change in meteorological conditions such as weakened winds and stable weather conditions led to the accumulation of air pollutants in Wuhan after the long-range transport. The contribution from Wuhan and surrounding cities to the PM2.5 concentrations was determined to be 67.4% during this period. Under the complex regional transport of pollutants from surrounding cities, the NCP, East China, and South China, the five episodes resulted in 30 haze days in Wuhan. The findings reveal important roles played by transregional and intercity transport in haze formation in Wuhan. | Miaomiao LU Xiao TANG Zifa WANG Lin WU Xueshun CHEN Shengwen LIANG Hui ZHOU Huangjian WU Ke HU Longjiao SHEN Jia YU Jiang ZHU | 2019 | Advances in Atmospheric Sciences2019，36，11： | 10 |
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