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| 1 | Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer显示文摘Inflammatory bowel diseases are characterised by inflammation that compromises the integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has evolved complex mechanisms to control and regulate bacterial interactions with the mucosal surface. Apical tight junction proteins are critical in the maintenance of epithelial barrier function and control of paracellular permeability. The characterisation of alterations in tight junction proteins as key players in epithelial barrier function in inflammatory bowel diseases is rapidly enhancing our understanding of critical mechanisms in disease pathogenesis as well as novel therapeutic opportunities. Here we give an overview of recent literature focusing on the role of tight junction proteins, in particular claudins, in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer. | Jonathan Landy Emma Ronde Nick English Sue K Clark Ailsa L Hart Stella C Knight Paul J Ciclitira Hafid Omar Al-Hassi | 2016 | World Journal of Gastroenterology2016，22，11： | 39 |
| 2 | 单程高增益1.9μm光纤气体拉曼激光器显示文摘报道了基于空心光子晶体光纤中氢气分子振动受激拉曼散射(SRS)的单程高增益1.9μm光纤气体激光器。用一个线偏振1064nm亚纳秒脉冲微芯激光器抽运一段长6.5m、充高压氢气的低损耗负曲率空心光纤,实现了到氢气分子一级振动斯托克斯波1907nm的有效转换。气压为2.3MPa时最大能量转换效率大于27%,相应的量子转换效率大于48%,激光平均功率约为10mW,峰值功率大于2000W。为实现高功率、窄线宽、大范围调谐的紧凑型中红外光纤激光器提供了一条潜在的有效途径。 | 王泽锋 于飞 William J Wadsworth Jonathan C Knight | 2014 | 光学学报2014，34，8： | 15 |
| 3 | The use of subtelomeric probes to study mental retardation 显示文摘 | Knight SJ Flint J | 2004 | Methods Cell Biol2004，75，： | 1 |
| 4 | Stimulation of c Jun kinase and mitogen-activated protein kinase by isehemia and reperfusion in the perfused rat heart 显示文摘 | KNIGHT R J BUXTON D B | 1996 | Biochemical and Biophysical Research Communications1996，218，： | 1 |
| 5 | Photonic crystal fibers 显示文摘 | KNIGHT J C | 2003 | Nature2003，424，7： | 1 |
| 6 | Clinical efficacy of a single injection of ceftiofur crystalline f ree acid sterile injectable suspension versus three daily injections of ceftiofur sodium sterile powder for t he treatment of foot rot in feedlot cattle显示文摘 | Van Donkersgoed J Dussault M Knight P | 2008 | Vet Ther2008，9，2： | 1 |
| 7 | Protection against heat stress-inducedoxidative damage in Arabidopsis involves calcium,abscisic acid,ethylene,and salicylic acid显示文摘 | Larkindale J Knight M R | 2002 | Plant Physiol2002，128，2： | 1 |
| 8 | Endlessly single-mode photonic crystal fiber显示文摘 | BIRKS T A KNIGHT J C RUSSELL P St J | 1997 | Opt Lett1997，22，96： | 1 |
| 9 | Endlessly single-mode photonic crystal fiber显示文摘 | Birks T A Knight J C Russell P St J | 1997 | Opt Lett1997，22，13： | 1 |
| 10 | Soliton Effects in Photonic Crystal Fibers at 800 nm显示文摘 | Wadsworth W J Knight J C Ortigosa-Blanch A | 2000 | Electron Lett2000，36，： | 1 |
| 11 | All si-lica single-mode optical fiber with photonic crystal cladding显示文摘 | Knight J C Birks T A Russell P St J | 1996 | Optics Letters1996，21，19： | 1 |
| 12 | Highly birefringence photonic crystal fibers显示文摘 | Ortigasta-Blanch A Knight J C Wadsworth W J | 2000 | Opt Lett2000，25，9： | 1 |
| 13 | Plant thermal hysteresis proteins显示文摘 | URRUTIA M E DUMAN J G KNIGHT C A | 1992 | Biochim Biophys Acta1992，1121，1： | 1 |
| 14 | Metabolic differences between 2-hydroxy-4-(methylthio) butanoic acid (HMB,Alimet) and D,1-methionine (DLM) during heat stress显示文摘 | Dibner J J Swick R A Knight C D | 1992 | Poult Sci1992，71，： | 1 |
| 15 | All-silica single-mode optical fiber with photonic crystal cladding显示文摘 | KNIGHT J C BIRKS T A RUSSELL P St J | 1996 | Opt Lett1996，21，19： | 1 |
| 16 | Control of mammary involution by insulin-like growth factor binding proteins:Role of prolactin显示文摘 | Flint D J Tonner E Knight C H | 2001 | Livestock Production Science2001，70，： | 1 |
| 17 | Neutrophilia and congestive heart failure after acute myocardia linfarction显示文摘 | Kyne L Hausdorff J M Knight E | 2000 | Am Heart J2000，139，： | 1 |
| 18 | Prdx! inbibits tumorigenesis via regulating PTEN/AKT activity显示文摘 | Cao J Schulte ] Knight A | 2009 | EMBO J2009，28，10： | 1 |
| 19 | Genome size evolu- tion in relation to leaf strategy and metabolic rates revisited 显示文摘 | Beaulieu J M Leitch I J Knight C A | 2007 | Annals of Botany2007，99，： | 1 |
| 20 | Inhibition of recrystallization of ice by inset thermal hysteresis proteins: a possible cryopro- tective role显示文摘 | Knight C A Duman J G | 1986 | Cryobiology1986，23，： | 1 |
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