|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Secondary non-resectable liver tumors:A single-center living-donor and deceased-donor liver transplantation case series显示文摘Background: During the last decades, deceased-donor liver transplantation (DDLT) has gained a place in the therapeutic algorithm of well-selected patients harbouring non-resectable secondary liver tumors. Living-donor LT (LDLT) might represent a valuable means to further expand this indication for LT. Methods: Between 1985 and 2016, twenty-two adults were transplanted because of neuroendocrine ( n = 18, 82%) and colorectal metastases ( n = 4, 18%);50% received DDLT and 50% LDLT. In LDLT, 4 (36%) right and 7 (64%) left grafts were used;the median graft-to-recipient-weight ratios (GRWR) were 1.03%(IQR 0.86%- 1.30%) and 0.59%(IQR 0.51%- 0.91%), respectively. Median post-LT follow-up was 64 months (IQR 17–107) in the DDLT group and 40 months (IQR 35–116) in the LDLT group. DDLT and LDLT recipients were compared in terms of overall survival, graft survival, postoperative complications and recurrence. Results: The 1- and 5-year actuarial patient survivals were 82% and 55% after DDLT, 100% and 100% after LDLT, respectively ( P < 0.01). One- and 5-year actuarial graft survivals were 73% and 36% after DDLT, 91% and 91% after LDLT ( P < 0.01). The outcomes of right or left LDLT were comparable. Donor hepatectomy proved safe, and one donor experienced a Clavien IIIb complication. Bilirubin peak was significantly lower after left hepatectomy compared with that after right hepatectomy [1.3 (IQR 1.2–2.2) vs. 3.3 (IQR 2.3–5.2) mg/dL;P = 0.02]. Conclusions: The more recent LDLT series compared favorably to our DDLT series in the treatment of secondary liver malignancies. The absence of portal hypertension and the use of smaller left grafts make recipient and donor surgeries safe. The safety of the procedures and lack of interference with the scarce allograft pool are expected to lead to a more frequent use of LDLT in the field of transplant oncology. | Jan Lerut Samuele Iesari Gaetan Vandeplas Tiziana Fabbrizio Kevin Ackenine Milton Eduardo Inostroza Nunez Mina Komuta Laurent Coubeau Olga Ciccarelli Eliano Bonaccorsi-Riani | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，5： | 2 |
| 2 | Mutations of the p53 gene in the stool of patients with respectable colorectal 显示文摘 | Eguchi S Kohara N Komuta K | 1996 | Cancer1996，77，8： | 1 |
| 3 | Histological diver- sity in cholangiocellular carcinoma reflects the different cholangio- cyte phenotypes 显示文摘 | Komuta M Govaere O Vandecaveye V | 2012 | Hepatology2012，55，6： | 1 |
| 4 | Administration of a polysaccharide from Grifola frondosa stimulates immune function of normal mice显示文摘 | KODAMA N KOMUTA K NANBA H | 2004 | J Med Food2004，7，2： | 1 |
| 5 | Assessment of Gd-EOB-DT- PA-enhaneed MRI for HCC and dysplastic nodules and compari- son of detection sensitivity versus MDCT显示文摘 | Inoue T Kudo M Komuta M | 2012 | J Gastroentero]2012，47，9： | 1 |
| 6 | Phase II study of S-1 monotherapy in platinum-refractory, ad- vanced non-small cell lung cancer显示文摘 | Shiroyama T Komuta K Imamura F | 2011 | Lung Cancer2011，74，1： | 1 |
| 7 | Bmi-1 gene is upregulated in early-stage hepatocellular caicinoma and correlates with ATP-binding cassette transporter B1 expression显示文摘 | Effendi K Mori T Komuta M | 2010 | Cancer Sci2010，101，3： | 1 |
| 8 | Effect of Maitake (Grifola frondosa)D-Fraction on the activation of NK cells in cancer patients显示文摘 | Kodama N Komuta K Nanba H | 2003 | J Med Food2003，6，4： | 1 |
| 9 | Detection of carcinoembryonic antigen mRNA in the mesenteric vein of patients with resectable colorectal cancer显示文摘 | Furui J Komuta K | 1998 | Surg Today1998，28，7： | 1 |
| 10 | Administration of a polysaccharide from Grifola frondosa stimulates immune function of normal mice显示文摘 | Kodama N Komuta K Nanba H | 2004 | J Med Food2004，7，2： | 1 |
| 11 | Pleiotrophin induces neurite outgrowth and up-regulates growth-associated protein (GAP)-43 mRNA through the ALK/GSK3β/β-catenin signaling in developing mouse neurons显示文摘 | Hiroko Yanagisawa Yukari Komuta Hitoshi Kawano Masashi Toyoda Kazunori Sango | 2009 | Neuroscience Research2009，，1： | 1 |
| 12 | Occurrence of hematog' enous metastasis and serum levels of thymidine phosphorylase in eoloreetal cancer显示文摘 | Haraguchi M Komuta K Akashi A | 2003 | Oncol Rep2003，10，： | 1 |
| 13 | Pleiotrophin induces neurite outgrowth and up-regulates growth-associated protein (GAP)-43 mRNA through the ALK/GSK3β/β-catenin signaling in developing mouse neurons显示文摘 | Hiroko Yanagisawa Yukari Komuta Hitoshi Kawano Masashi Toyoda Kazunori Sango | 2009 | Neuroscience Research2009，，1： | 1 |
| 14 | Phase Ⅱ study of S-1 monotherapy in platinum-refractory,advanced non-small cell lung cancer显示文摘 | Shiroyama T Komuta K Imamura F | | 0，，01： | 1 |
| 15 | Keratin 19: a key role player in the invasion of human hepatocellular carcinomas 显示文摘 | Govaere O Komuta M Berkers J | 2014 | Gut2014，63，4： | 1 |
| 16 | Enhanced quanumyield in porphyin hetye rodimer solar cell 显示文摘 | Takahashi K Nanbu H Komuta T | 1993 | Chem Lett1993，25，2： | 1 |
| 17 | Clinical diagnosis and staging of cholangiocarcinoma 显示文摘 | Blechacz B Komuta M Roskams T | 2011 | Nat Rev Gastroenterol Hepatol2011，8，： | 1 |
| 18 | Effect s of D-Fraction,a polysac charide from Grifola frondosa on tumor growth involve activation of NK cells显示文摘 | Kedama N Komuta K Sakai N | 2002 | Biol Pharm Bull2002，39，： | 1 |
| 19 | Attempt to rescue discarded human liver grafts by end ischemic fypothermic oxygenated machine perfusion显示文摘 | Vekemans K van Pelt J Komuta M | 2011 | Transplantation Proceedings2011，，09： | 1 |
| 20 | Accelerated expres- sion of a Myc target gene MinaS3 in aggressive hepatocellular carci- noma显示文摘 | Ogasawara S Komuta M Nakashima O | 2010 | Hepatol Res2010，40，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员