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| 1 | Significance of hepatitis virus infection in the oncogenicinitiation of hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is one of the most common causes of cancer-related death worldwide. Chronic infection of hepatitis B virus(HBV) and/or hepatitis C virus(HCV) is a major risk factor in the development of the HCC, independently from excessive alcohol abuse and metabolic disease. Since the biology of HBV and HCV is different, their oncogenic effect may go through different mechanisms, direct and/or indirect. Viral hepatitis infection is associated with cellular inflammation, oxidative stress, DNA damage, that may lead to subsequent hepatic injuries such as chronic hepatitis, fibrosis, cirrhosis, and finally HCC. Direct oncogenic properties of these viruses are related with their genotypic characteristics and the ability of viral proteins to interact with host proteins, thus altering the molecular pathways balance of the cells. In addition, the integration of HBV DNA, especially the gene S and X, in a particular site of the host genome can disrupt chromosomal stability and may activate various oncogenic mechanisms, including those in hematopoietic cells. Recently, several studies also had demonstrated that viral hepatitis could trigger the population of hepatic cancer stem cells. This review summarize available pre-clinical and clinical data in literature regarding oncogenic properties of HBV and HCV in the early initiation of HCC. | Caecilia HC Sukowati Korri E El-Khobar Susan I Ie Beatrice Anfuso David H Muljono Claudio Tiribelli | 2016 | World Journal of Gastroenterology2016,22,4: | 18 |
| 2 | Seroepidemiology and occult hepatitis B virus infection in young adults in Banjarmasin, Indonesia显示文摘 | Erica Darmawan Turyadi Korri E. El‐Khobar Ni Ketut Dias Nursanty Meta D. Thedja David Handojo Muljono | 2015 | Virol2015,,2: | 2 |
| 3 | Cognition and International Entrepreneurship : Implications for Research on International Opportunity Recognition and Exploitation 显示文摘 | ZAHRA S A KORRI J YU J | 2005 | International Business Review2005,14,2: | 1 |
| 4 | Cognition and International Entre- preneurship: Implications for Research on International Opportu- nity Recognition and Exploitation 显示文摘 | Zahra S A Korri J S Yu J F | 2005 | International Business Re- view2005,14,2: | 1 |
| 5 | Note on the relationship between probabilistic and fuzzy clustering 显示文摘 | Korris Chung K F Wang S T Shen H B | 2004 | Soft Computing2004,8,7: | 1 |
| 6 | Note on the relationship between probabilistic and fuzzy clustering 显示文摘 | WANG Shi-tong Korris Chung K F SHEN Hong-bin | 2004 | Soft Computing2004,8,5: | 1 |
| 7 | Effect of artificial ocelusal interferences depends on previous experience of temporomandibular disorders显示文摘 | Le Bell Y J~ms~ T Korri S | 2002 | Acta Odontol Scand2002,60,4: | 1 |
| 8 | Towardbioelectronics:specific DNA recognition based on anoligonucleotide-functionalized polypyrrole显示文摘 | Korri Y H Garnier F Srivastava P | 1997 | J AmChem Soc1997,119,31: | 1 |
| 9 | Cognition and international entrepreneurship:implications for research on international opportunity recognition and exploitation显示文摘 | Zahra S A Korri J S Yu J F | 2005 | International Business Review2005,14,2: | 1 |
| 10 | Effect of artificial occlusal inter-ferences depends on previous experience of temporomandibular disor- ders 显示文摘 | Le BellY Jamsa T Korri S | 2002 | Acta Odontol Scand2002,60,4: | 1 |
| 11 | Role of hepatitis B virus in development of hepatocellular carcinoma:Focus on covalently closed circular DNA显示文摘Chronic infection with hepatitis B virus(HBV)remains a major global health problem,especially in developing countries.It may lead to prolonged liver damage,fibrosis,cirrhosis,and hepatocellular carcinoma.Persistent chronic HBV infection is related to host immune response and the stability of the covalently closed circular DNA(cccDNA)in human hepatocytes.In addition to being essential for viral transcription and replication,cccDNA is also suspected to play a role in persistent HBV infections or hepatitis relapses since cccDNA is very stable in non-dividing human hepatocytes.Understanding the pathogenicity and oncogenicity of HBV components would be essential in the development of new diagnostic tools and treatment strategies.This review summarizes the role and molecular mechanisms of HBV cccDNA in hepatocyte transformation and hepatocarcinogenesis and current efforts to its detection and targeting. | Claryssa Bianca Elizabeth Sidhartha Claudio Tiribelli Korri Elvanita El-Khobar Caecilia H C Sukowati | 2022 | World Journal of Hepatology2022,14,5: | 1 |
| 12 | Progressive paraparesis with sensorineural deafness and leukoencephalopathy revealing neurobrucellosis显示文摘 | Awada A Korri H Issa Z | 2011 | Rev Neurol(Paris)2011,167,: | 1 |
| 13 | A case of Kleine-Levin syndrome with a complete and sustained response to carbamazepine显示文摘 | E1 Hajj T Nasreddine S Korri H | 2009 | Epilepsy Behav2009,15,3: | 1 |
| 14 | Effect of artificial occlu-sal interferences depends on previous experience of tem-poromandibular disorders显示文摘 | Le Bell Y Jamsa T Korri S | 2002 | Acta Odontol Scand2002,60,: | 1 |
| 15 | Antioxidants in Foods: State of the science important to the food industry显示文摘 | John WF Kong AN Korry JH | 2011 | J Agrie Food Chem2011,59,: | 1 |
| 16 | Clustering analysis of gene expression data based on semisupervised visual clustering algorithm 显示文摘 | Korris Chung K F WANG Shi-tong DENG Zhao-hong | 2006 | Soft Computing2006,10,11: | 1 |
| 17 | Possibility theoretic clustering and its oreliminary application to large image segmentation 显示文摘 | Korris Chung K F WANG Shi-tong XU M | 2007 | Soft Computing2007,11,2: | 1 |
| 18 | Robust fuzzy clustering neural network based on epsiloninsensitive loss function显示文摘 | WANG Shi-tong Korris Chung K F DENG Zhao-hong | 2007 | Applied Soft Computing2007,7,2: | 1 |
| 19 | A cognitive approach to international entrepreneurship显示文摘 | Zahra S Korri J S and Yu J | 2005 | International Business Review2005,14,2: | 1 |
| 20 | Effect of artificial occlusal interferences depends on previous experience of temporo mandibular disorders显示文摘 | Bell YL Jamsa T Korri S | 2002 | Acta Odontol Scand2002,60,4: | 1 |