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1Meeting report:a hard look at the state of enamel research显示文摘The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines(ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research(NIDCR). Discussion topics included model organisms, stem cells/cell lines, and tissues/3 D cell culture/organoids. Scientists from a number of disciplines,representing institutions from across the United States, gathered to discuss advances in our understanding of enamel, as well as future directions for the field.ophir d klein olivier duverger wendy shaw rodrigo s lacruz derk joester janet moradian-oldak megan k pugach j timothy wright sarah e millar ashok b kulkarni john d bartlett thomas gh diekwisch pamela den besten james p simmer 2017International Journal of Oral Science2017,9,4:3
2脂氧合酶介导的杀虫剂N-位脱甲基作用的体外实验显示文摘目的 探讨细胞色素P450加单氧酶系以外的代谢途径对杀虫剂的脱烷基作用 ,检测脂氧合酶 (LOX)介导的灭害威等的N 位脱甲基作用。方法 通过Nash反应检测大豆脂氧合酶 (SLO)对灭害威作用产生甲醛的量 ,反映其介导杀虫剂的N 位脱甲基反应速率。结果 SLO对灭害威的脱甲基作用与反应时间以及SLO浓度、灭害威和过氧化氢的浓度呈依赖关系。在最佳反应条件下 ,SLO产生甲醛的最大反应速度 (Vmax)为 1 8nmol·min- 1 ·nmol- 1 。SLO对灭害威的米氏常数 (Km)值为 3 .4mmol/L ,对过氧化氢的Km值为 2 35μmol/L。去甲二氢愈创木酸 (NDGA)、棉子醇 (gossypol)和芬宁东(phenidone)对脱甲基反应的强烈抑制作用提示 ,SLO起催化作用。还原型谷胱甘肽 (GSH)或二硫苏糖醇参与反应时 ,甲醛的累积量明显降低 ,表明SLO对灭害威脱甲基作用时 ,产生自由基。丁羟基甲苯(BHT)和丁羧基苯甲醚 (BHA)对甲醛的产生的抑制作用进一步支持这一论点。除灭害威外 ,发现其他的杀虫剂也发生N 位脱甲基作用 ,只是相对反应速率较低。胡建安 Kulkarni Arun P 2002中华劳动卫生职业病杂志2002,20,6:3
3Time and pH Dependent Colon Specific, Pulsatile Delivery of Theophylline for Nocturnal Asthma显示文摘Mastiholimath V S Dandagi P M Samata Jain S Gadad A P Kulkarni A R 2007International Journal of Pharmaceutics2007,328,:1
4Improved selectivity in the toluene alkylation reaction through understanding and optimising the process variables显示文摘BREEN J P BURCH R KULKARNI M 2007Appl Catal A: General2007,316,12:1
5Deformation and Fracture Behavior of Cast and Extruded 7075Al-SiCP Composites at Room and Elevated Temperature显示文摘Kulkarni M D Pobi P S Prasad R C 1996Mater Trans JIM1996,37,:1
6Superhydrophobic silica aerogels based on methyltrimethoxysilane precursor显示文摘Venkateswara R Kulkarni M M Amalnerkar D P 2003J Non-crystalline Solids2003,330,:1
7A comprehensive review of direct carbon fuel cell technology显示文摘Giddey S Badwal S P S Kulkarni A 2012Progress in Energy and Combustion Science2012,38,3:1
8Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced lupus nephritis 显示文摘Lech M Skuginna V Kulkarni O P 2010J Pathol2010,220,5:1
9Smart grid communica- tions: Overview of research challenges,solutions,and stand- ardization activities显示文摘Fan Z Kulkarni P Gormus S 2013IEEE Communications Surveys Tutorials2013,15,1:1
10Improved selectivity in the toluene alkylation reaction through understanding and optimising the process variables 显示文摘Breen J P Burch R Kulkarni M 2007Applied Catalysis A General2007,316,1:1
11Digital circuit applications of resonant tunneling devices 显示文摘Maznmder P Kulkarni S Bhattacharya M 2000Proceedings of IEEE2000,86,4:1
12显示文摘Rao C N R Kulkarni G U Thomas P J 2000Chem Soc Rev2000,29,1:1
13显示文摘Patro P K Kulkarni A R Gupta S M 2007Phys B: Condensed Matter2007,400,12:1
14Effect of 5-HT1A and 5- HT2A/2C receptor modulation on neuroleptic-induced vacuous chewing movements显示文摘NAIDU P S KULKARNI S K 2001Eur J Pharmacol2001,428,1:1
15Cancer/testis anti?gens and urological malignancies 显示文摘Kulkarni P Shiraishi T Rajagopalan K et aI 2012Nat Rev U rol2012,9,7:1
16查看详情显示文摘Humphry K J Kulkarni P M Weitz D A Morris J F Stone H A 0,,:1
17Basmati rice : a review显示文摘Bhattacharjee P Singhal R S Kulkarni P R 2002International Journal of Food Science & Technology2002,37,1:1
18An ant colony approach for clustering 显示文摘SHELOKAR P S JAPARAMAN V K KULKARNI B D 2004Analytica Chimica Acta2004,,509:1
19A proteomic analysis of adult rat bone reveals the presence of cartilage/chondrocyte markers显示文摘SCHREIWEIS M A BUTLER J P KULKARNI N H 2007Journal of Cellular Biochemistry2007,101,:1
20显示文摘Khanna P K Kulkarni M V Singh N 2006Materials Chemistry and Phys2006,95,:1
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