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    题名 作者 年代 出处 被引量
1Non-suicidal self-harm is linked to suicidal thoughts in Chinese adolescents with mood disorders:a cross-sectional report显示文摘Non-suicidal self-injury (NS SI) refers to any intentional,self-inflicted behavior that causes direct damage to body tissues (Kerr et al.,2010),and has emerged as a challenging public health issue worldwide,especially among adolescents.The most common presentations of NSSI include skin-cutting,severe scratching,and burning (Whitlock et al,2006).Yixin WANG Jianbo LAI Chanchan HU Hongbo MENG Duo LYU Shaohua HU 2021Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021,22,3:5
2High-level expression and purification of Plutella xylostella acetylcholinesterase in Pichia pastoris and its potential application显示文摘The acetylcholinesterase 2(AChE2)cloned from Plutella xylostella was first successfully expressed in methylotrophic yeast Pichia pastoris GS115.One transformant with high-level expression of the recombinant AChE(rAChE,23.2 U mL^(-1)in supernatant)was selected by plating on increasing concentrations of antibiotic G418 and by using a simple and specific chromogenic reaction with indoxyl acetate as a substrate.The maximum production of r ACh E reached about 11.8 mg of the enzyme protein per liter of culture.The r ACh E was first precipitated with ammonium sulfate(50%saturation)and then purified with procainamide affinity column chromatography.The enzyme was purified 12.1-fold with a yield of 22.8%and a high specific activity of 448.3 U mg^(-1).It was sensitive to inhibition by methamidophos and pirimicarb,the calculated 50% inhibitory concentration(IC_(50))values of the two pesticides were 0.357 and 0.888 mg L^(-1),respectively,and the calculated 70% inhibitory concentration(IC_(70))values were 0.521 and 0.839 mg L^(-1),respectively.The results suggested that it has a potential application in the detection of pesticide residues.LIU Niu CHE Jun LAI Duo WEN Jin-jun XU Han-hong 2017Journal of Integrative Agriculture2017,16,6:2
3Promotion of the efficient metabolic maturation of human pluripotent stem cell-derived hepatocytes by correcting specification defects显示文摘Dongxin Zhao Song Chen Shuguang Duo Chengang Xiang Jun Jia Mina Guo Wei Lai Shichun LU Hongkui Deng 2013Cell Research2013,23,1:2
4Corrigendum to‘Dual ultra-wideband(UWB)radar-based sleep posture recognition system:Towards ubiquitous sleep monitoring’[Engineered Regeneration 4(2023)36-43]显示文摘The authors regret that the name of the ethic committee that approved the study and the reference number was omitted from the published paper.In this research,all participants signed an informed consent after receiving an oral and written description of the experiment before the start of the experiment.The study was approved by the Human Subjects Ethics HSEARS20210127007.Derek Ka-Hei Lai Li-Wen Zha Tommy Yau-Nam Leung Andy Yiu-Chau Tam Bryan Pak-Hei So Hyo Jung Lim Daphne Sze Ki Cheung Duo Wai-Chi Wong James Chung-Wai Cheung 2023Engineered Regeneration2023,4,2:0
5A Novel Model for Context Conflict Resolution Basec on Set Pair Analysis显示文摘DUO Lin LAI Xiaoyang LIU Zengli CHEN Xi 2014China Communications2014,11,A02:0
6Dual ultra-wideband(UWB)radar-based sleep posture recognition system:Towards ubiquitous sleep monitoring显示文摘Sleep posture monitoring is an essential assessment for obstructive sleep apnea(OSA)patients.The objective of this study is to develop a machine learning-based sleep posture recognition system using a dual ultra-wideband radar system.We collected radiofrequency data from two radars positioned over and at the side of the bed for 16 patients performing four sleep postures(supine,left and right lateral,and prone).We proposed and evaluated deep learning approaches that streamlined feature extraction and classification,and the traditional machine learning approaches that involved different combinations of feature extractors and classifiers.Our results showed that the dual radar system performed better than either single radar.Predetermined statistical features with random forest classifier yielded the best accuracy(0.887),which could be further improved via an ablation study(0.938).Deep learning approach using transformer yielded accuracy of 0.713.Derek Ka-Hei Lai Li-Wen Zha Tommy Yau-Nam Leung Andy Yiu-Chau Tam Bryan Pak-Hei So Hyo-Jung Lim Daphne Sze Ki Cheung Duo Wai-Chi Wong James Chung-Wai Cheung 2023Engineered Regeneration2023,4,1:0
7建立具有体内胚内和胚外发育潜能的多能干细胞显示文摘文章简介在已知的体外培养的干细胞类型当中,多能干细胞具有最高的发育潜能,能够形成构成成年个体的所有细胞类型。但是,多能干细胞很难在体内发育过程中形成胚外的胎盘组织。Yang Yang Bei Liu Jun Xu Jinlin Wang Jun Wu Cheng Shi Yaxing Xu Jiebin Dong Chengyan Wang Weifeng Lai Jialiang Zhu Liang Xiong Dicong Zhu Xiang Li Weifeng Yang Takayoshi Yamauchi Atsushi Sugawara Zhongwei Li Fangyuan Sun Xiangyun Li Chen Li Aibin He Yaqin Du Ting Wang Chaoran Zhao Haibo Li Xiaochun Chi Hongquan Zhang Yifang Liu Cheng Li Shuguang Duo Ming Yin 沈浣 Juan Carlos Izpisua Belmonte 邓宏魁 2018科学新闻2018,0,4:0
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